scholarly journals Histamine Blood Concentration in Ischemic Heart Disease Patients

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Vladimir Zdravkovic ◽  
Suzana Pantovic ◽  
Gvozden Rosic ◽  
Aleksandra Tomic-Lucic ◽  
Nemanja Zdravkovic ◽  
...  

The aim of this study was to investigate histamine blood concentration in subjects suffering from different types of ischemic heart diseases during the period of eight days. Our results showed that the histamine blood level was associated with different types of ischemic heart diseases. The blood histamine level in all investigated patients was significantly higher when compared to control subjects (44.87 ± 1.09 ng mL−1), indicating the increase of histamine release in patients suffering from coronary diseases. In patients suffering from ACS-UA and ACS-STEMI, the second day peak of histamine level occurs (90.85 ± 6.34 ng mL−1and 121.7 ± 6.34 ng mL−1, resp.) probably as the reperfusion event. Furthermore, our data suggest that histamine can be additional parameter of myocardial ischemia along with cardiac specific enzymes and may prove to be an excellent single prognostic marker for multitude of ischemic heart diseases.

2021 ◽  
Vol 19 (3) ◽  
pp. 130-132
Author(s):  
Sarath Kumar Reddy B ◽  

Background: Ischemic heart disease (IHD) is one of the principle causes of morbidity and of mortality in women1. Ischemic heart disease may manifest clinically as either chronic stable angina or acute coronary syndrome2 (ACS). Traditional risk factors (hypertension, diabetes, etc.) contribute to the development of IHD in both women and men. Some risk factors are unique to women (e.g., pregnancy-related complications, menopause), which cause increased mortality in women Aim: To study the risk factors and clinical profile of ischemic heart disease in women. Materials And Methods: Hospital-based prospective, cross-sectional study done in 50 patients with ischemic heart disease. Patients with a history of Chest pain suggestive of ischemic heart diseases and Electrocardiogram and cardiac biomarkers suggestive of ischemic heart disease were included in the study. Results: Maximum incidence of ischemic heart diseases is seen in the 6th decade. Mean age is 58.92 + 2.8years. 64%of the patients presented with chest pain, and 36% patients presented without any chest pain. After chest pain, the most common symptom was palpitations, seen in 56% patients, followed by sweating (44%). 30% presented to the medical facility within 3hours. 88% were diagnosed with acute coronary syndrome, and 12% were diagnosed with chronic stable angina. Women specific risk factors include the pregnancy-related complications seen in 10% patients, menopause attained in 86% patients, PCOS seen in 08% patients, use of oral contraceptive pills noticed in 08% patients, Other risk factors identified were hypothyroidism in 16% patients, connective tissue disorders like rheumatoid arthritis seen in 12% of the patients. Conclusion: Awareness regarding atypical symptoms as well as other symptoms of IHD should be created among women to avoid delayed complications. Simple lifestyle modifications like physical activity, diet modifications, etc., will reduce the number of women at risk for IHD.


Author(s):  
Hsin-I Shih ◽  
Tzu-Yuan Chao ◽  
Yi-Ting Huang ◽  
Yi-Fang Tu ◽  
Tzu-Ching Sung ◽  
...  

Natural disasters have negative health impacts on chronic diseases in affected populations. Severely affected areas are usually rural areas with limited basic infrastructure and a population have that has limited access to optimal healthcare after a disaster. Patients with cardiovascular diseases are required to maintain quality care, especially after disasters. A population-based case-control study enrolled adults from the National Health Insurance Registry who had ischemic heart disease and cerebrovascular disease histories and lived in the area affected by Typhoon Morakot in 2009. Monthly medical visits for acute cerebrovascular and ischemic heart diseases markedly increased at approximately 1–2 months after the typhoon. Survival analysis during the two years following the typhoon indicated a significant increase in mortality in adults with an acute ischemic heart disease history who lived in the severely affected area. Mortality hazard analysis showed that among affected adults with previous cerebrovascular diseases and acute ischemic heart diseases, patients with diabetes (adjusted hazard ratio [HR]: 1.3–1.7), Chronic Kidney Disease (CKD) (adjusted HR: 2.0–2.7), chronic obstructive pulmonary diseases (COPD) and asthma (adjusted HR: 1.7–2.1), liver cirrhosis (adjusted HR: 2.3–3.3) and neoplasms (adjusted HR: 1.1–2.1) had significantly increased mortality rates. Consequently, high-quality and accessible primary healthcare plans should be made available to maintain and support affected populations after disasters.


2011 ◽  
Vol 2 (1) ◽  
pp. 51-54
Author(s):  
Ol'ga Leonidovna Barbarash ◽  
Yuliya Vyacheslavovna Bayrakova ◽  
Evgeniya Mikhaylovna Kurguzova

Summary. The need for statins in patients with acute and chronic forms of coronary heart disease is now beyond doubt. However, there is still a view that from the perspective of safety it is necessary to cancel statins before a surgery and reinstitute them after a surgery. This review examines the feasibility and safety of preoperative statin therapy in patients with ischemic heart diseases before planned coronary bypass surgery.


World Science ◽  
2019 ◽  
Vol 2 (11(51)) ◽  
pp. 4-11
Author(s):  
Mostovyi S. ◽  
Dynnyk O. ◽  
Marunchyn N.

Introduction. It is known that patients with ischemic heart diseases have endothelial dysfunction, but there is lack of research about microcirculation in these patients with diffuse liver diseases, especially diagnosed with digital capillaroscopy. Aim. To investigate hemodynamic disorders and microcirculation in patients with chronic ischemic heart disease depending on the presence of diffuse liver diseases and its severity with the digital capillaroscopy. Materials and methods. Our prospective study included 187 patients according to the criteria of inclusion. The data of echocardiography and digital capillaroscopy were analysed. Results. In our research in patients with ejection fraction less than 40% there was revealed thickening of the wall of the left ventricle, low blood supply in arterial and venous parts of capillaries. Patients with ejection fraction less than 40% and progressive diffuse liver diseases had advanced thickening of the wall of the left ventricle. Patients with liver cirrhosis had more adverse changes in hemodynamics. Patients with ischemic heart disease and diffuse liver disease had the worst capillary blood supply. Patients with ejection fraction less than 40% and diffuse liver diseases had structural changes of capillaries such as bi-, trifurcation and bushy forms. Conclusions. So, diffuse liver diseases, especially severe, cause endothelial dysfunction in patients with ischemic heart diseases. Digital capillaroscopy is a noninvasive method for microcirculation diagnosis and patients’ monitoring.


2012 ◽  
Vol 7 (2) ◽  
pp. 73-75 ◽  
Author(s):  
Shohda Khatun ◽  
Ashis Kumar Biswas ◽  
Sojeeb Dhar ◽  
Rajan Karmakar ◽  
Md Abu Siddique ◽  
...  

The aim of the stuey is to evaluate the association of periodontal condition of patients with Ischemic Heart disease at a university hospital in Bangladesh. This study was done at Bangabandhu Sheikh Mujib Medical University. Two group of patients was selected. Case group of 25 patients with history ischemic heart disease was selected at OPD of cardiology department another control group 25 patient was selected at dental OPD of BSMMU. Data were analyzed by SPSS, Version 10. In this study, The mean age (±SD) of patients was 50.4±8.49 years in the case group and 49.6±10.9 years in the control group. 50 patients consisting of 26 males (52%) and 24 females (48%) were examined. Study showed that probing depth, plaque index, gingival index, bleeding index, gingival recession and clinical attachment level is more in patient with ischemic heart diseases. This study showed higher incidence and more severe periodontal diseases in patients with ischemic heart diseases. DOI: http://dx.doi.org/10.3329/uhj.v7i2.10842 University Heart. Journal Vol. 7, No. 2, July 2011


2005 ◽  
Vol 62 (5) ◽  
pp. 343-348 ◽  
Author(s):  
Sandra Sipetic ◽  
Hristina Vlajinac ◽  
Vesna Stefanovic ◽  
Dejana Stanisavljevic

During the period between 1990 and 2002 in Belgrade population, almost every second person aged 30-69 years, died of some cardiovascular disease (CVD). Men, as compared to women, had higher standardized mortality rates from CVD (1.7 times), ischemic heart diseases (2.5 times), other heart diseases (1.6 times), and cerebrovascular diseases (1.3 times). During that period, the mortality from CVD increased by 18.6% in men, and by 10.0% in women. The increase in cerebrovascular disease mortality was 32.6% for men and 17.2% for women. Mortality from ischemic heart disease decreased twice as much in men (17.0%) than in woman (8.5%). In both sexes, the average age-specific mortality rates from CVD creased with the age. In women, the average age-specific mortality rates were 5 years behind those in men. In both sexes aged 30-34 years, the average mortality rate from CVD increased by 22.2% in men and by 14.1% in women, respectively.


Author(s):  
Dmitriy Okun'

The paper describes a fragment of the knowledge base of drug therapy for ischemic heart disease, hosted on the IACPaaS platform. Generally accepted medical terminology is used in the formation of knowledge.


2018 ◽  
Vol 3 (Issue 1) ◽  
pp. 16
Author(s):  
Leilim Actaiyeva ◽  
Kuat Abzaliyev ◽  
Simbat Abzaliyeva ◽  
Gulum Aldangarova

We present review of current evidence on ischemic heart disease in women. The risk factors, clinical manifestations, diagnosis and treatment  and prevention of ischemic heart diseases in women are discussed.


1976 ◽  
Vol 25 (1) ◽  
pp. 271-275 ◽  
Author(s):  
Ulf de Faire

From January 1971 to March 1973 all twin pairs in the Swedish Twin Registry below the age of 70, who became death-discordant, were continuously recorded. A total of 205 (78%) of the surviving cotwins were examined with respect to different manifestations of ischemic heart diseases (IHD) and several “environmental” and “biometric” risk factors. Among the death-discordant pairs, the cause of death was IHD in 57 pairs and other than IHD in 148 pairs. Analyses revealed that the prevalence rate of myocardial infarction, angina pectoris, pathologic Q-wave, and ST depressions in connection with exercise, were significantly higher among the surviving cotwins whose partners had died from IHD than those whose partners had died from other causes. The same trends were seen for most of the risk factors measured both singly and in combination, although not very pronounced. The results indicate a substantial genetic influence in the development of IHD. The genetic influence is possibly transmitted not only through some of the risk factors measured, but also through other factors, still unknown.


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