Improved Left Ventricular Diastolic Function with Exercise Training in Hypertension: A Doppler Imaging Study
Objective.To study the effects of 6 months’ exercise training on ventricular function in hypertensive patients.Methods.Both groups received routine anti-hypertensive pharmacological therapy and one received a 6 months’ exercise program in addition. All patients underwent incremental cardiopulmonary exercise test and echocardiography in baseline and after 6 months.Results.(1) In 6 months’ follow-up, PeakVO2, Powermax(max workload), AT (anaerobic threshold), VO2AT(VO2at anaerobic threshold), tAT(time from beginning to anaerobic threshold) (), were increased in the exercise group. HRrest(Heart rate at rest) was decreased (). LAVI (left atrial volume index), peak mitral filling velocities during early (E) and late (A) diastole E/A ratio, DT(deceleration time of the mitral E wave), IVST(Interventricular septum thickness in diastole), tissue Doppler indice Mean Ea/Aa ratio () were also improved. (2) Correlation analysis: 4 variates had significant effect on change of PeakVO2in the exercise group: age (), change of HRrest(), change of E/A (), change of Mean Ea/Aa (); Through analyzing 2 groups patients’ baseline values, their age (), VO2AT(), HRrest(), LAVI (), E/A () were found to be independent predictors of MeanEa/Aa. -value under .05 was considered statistically significant.Conclusion.6 months’ exercise could enhance hypertensive patients’ aerobic exercise level and diastolic function to a certain extent.