Psoriatic Arthritis and Diabetes: A Population-Based Cross-Sectional Study

Temporomandibular joint (TMJ) is commonly involved in various immune-mediated rheumatic disorders accounting for significant disability and impaired quality of life. The aim of our study was to assess inflammatory and immune parameters in patients with TMJ arthritis related to rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) and to identify potential relation with severity and dysfunction of TMJ pathology. We performed a cross-sectional study in a cohort of 433 consecutive RA, 32 JIA, 258 AS, and 103 PsA. Only patients presenting with clinically significant TMJ involvement (273) related to their rheumatic condition were included in the final analysis. TMJ involvement is traditionally described in chronic inflammatory rheumatic disorders, particularly in patients with higher levels of inflammation as detected in rheumatoid arthritis and psoriatic arthritis. Disease activity and severity, as well as biological and positive serological assessments (rheumatoid factor, anti-cyclic citrullinated peptide, IL-1) remain significant determinants of the severity of TMJ arthritis.

Download Full-text

Prevalence of disabilities and non-communicable diseases in an elderly population in the Telangana state, India: a population-based cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2020-041755 ◽

2021 ◽

Vol 11 (2) ◽

pp. e041755

Author(s):

Srinivas Marmamula ◽

Satya Brahmanandam Modepalli ◽

Thirupathi Reddy Kumbham ◽

Rajesh Challa ◽

Jill E Keeffe

Keyword(s):

Elderly Population ◽

Self Care ◽

The Elderly ◽

Population Based ◽

Cross Sectional Study ◽

Communicable Diseases ◽

Self Report ◽

Sectional Study ◽

Cross Sectional ◽

Non Communicable Diseases

ObjectivesTo assess the prevalence of disabilities (vision, hearing, mobility, cognitive, self-care and communication) and non-communicable diseases (NCDs) among the elderly population in two districts in Telangana, India.DesignPopulation-based cross-sectional study using a cluster random sampling method to select the study clusters.SettingElderly population in Khammam and Warangal districts were recruited. Detailed interviews were conducted by trained community health workers. Personal and demographic information such as age, gender, level of education and a self-report of NCDs was collected. The Washington Disability Questionnaire was administered to assess the presence of disabilities.Participants1821 participants aged ≥60 years, 54.5% were women, and 73.3% had no education.Primary outcome measurePrevalence of disabilities and NCDs.ResultsOverall, the prevalence of at least disability was 20.3% (95% CI 16.3 to 24.9). The prevalence of self- reported disabilities were: seeing (5.9%; 95% CI 4.4 to 7.8), mobility (12.8%; 95% CI 9.7 to 16.8), hearing (3.6%; 95% CI 2.7 to 4.8), cognition (4.8%; 95% CI 3.5 to 6.7), self-care (3.3%; 95% CI 2.3 to 4.7) and communication (1.8%; 95% CI 1.2 to 2.6). Overall, the prevalence of at least one NCD was 34.2% (95% CI 30.9 to 37.7). Hypertension was the most common systemic condition (25.4%; 95% CI 22.4 to 28.7), followed by diabetes (9.0%; 95% CI 7.3 to 11.0), and body pains (muscle-skeletal) (9.9%; 95% CI 8.1 to 12.2).ConclusionEvery fifth elderly person in the districts of Khammam and Warangal in Telangana had at least one self-reported disability. Besides, a third of the elderly had at least one NCD. There is a definite need to develop comprehensive public health strategies to address disabilities and NCDs in Telangana.

Download Full-text

Association between pyrethroid exposure and cardiovascular disease: A national population-based cross-sectional study in the US

Environment International ◽

10.1016/j.envint.2021.106545 ◽

2021 ◽

Vol 153 ◽

pp. 106545

Author(s):

Qingping Xue ◽

An Pan ◽

Ying Wen ◽

Yichao Huang ◽

Da Chen ◽

...

Keyword(s):

Cardiovascular Disease ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

National Population ◽

The Us

Download Full-text

Prevalence and risk factors of Helicobacter pylori infection in Wuwei, a high‐risk area for gastric cancer in northwest China: An all‐ages population‐based cross‐sectional study

Helicobacter ◽

10.1111/hel.12810 ◽

2021 ◽

Author(s):

Xiaofeng Wang ◽

Xiaochuang Shu ◽

Qiang Li ◽

Youpeng Li ◽

Zhaofeng Chen ◽

...

Keyword(s):

Risk Factors ◽

Gastric Cancer ◽

Helicobacter Pylori ◽

Northwest China ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Risk Area ◽

Cross Sectional ◽

High Risk Area

Download Full-text

Myopia, corneal endothelial cell density and morphology in a Japanese population-based cross-sectional study: the JPHC-NEXT Eye Study

Scientific Reports ◽

10.1038/s41598-021-85617-4 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Naohiko Aketa ◽

Miki Uchino ◽

Motoko Kawashima ◽

Yuichi Uchino ◽

Kenya Yuki ◽

...

Keyword(s):

Endothelial Cell ◽

Cell Density ◽

Contact Lenses ◽

Population Based ◽

Cross Sectional Study ◽

Corneal Endothelial Cell ◽

Endothelial Cell Density ◽

Sectional Study ◽

Cross Sectional ◽

Corneal Endothelial Cell Density

AbstractThis population-based cross-sectional study was performed to determine the mean corneal endothelial cell density (ECD), coefficient of variation (CV), and hexagonality (HEX), and their associations with myopia in Japanese adults living in Chikusei city. Of 7109 participants with available data, 5713 (2331 male and 3382 female) participants were eligible for analysis. After assessing the relationship between participant characteristics and spherical equivalent refraction (SER), the association of SER with the abnormal value of ECD (< 2000 cells/mm), CV (≥ 0.40), and HEX (≤ 50%) were determined using the logistic regression models adjusting for potential confounders (age, intraocular pressure, keratometric power, height, and antihypertensive drug use). In male participants, there was no statistically significant relationships between SER and endothelial parameters. In female participants, compared to emmetropia, SER ≤ − 6 D had significantly higher odds ratio (OR) of having the abnormal value of CV (OR = 2.07, 95% confidence interval [CI] 1.39–3.10) and HEX (OR = 2.04, 95% CI 1.29–3.23), adjusted for potential confounders, indicating that the high myopia was associated with the abnormal values of CV and HEX. Further adjustment for contact lenses wear partly attenuated these associations. Association between the SER and ECD was not detected.

Download Full-text