scholarly journals Utility of Nuclear Morphometry in Predicting Grades of Diffusely Infiltrating Gliomas

ISRN Oncology ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-8
Author(s):  
Dibyajyoti Boruah ◽  
Prabal Deb

Introduction. The ability to reliably differentiate neoplastic from nonneoplastic specimen and ascertain the tumour grade of diffusely infiltrating gliomas (DIGs) is often challenging. Aims and Objective. To evaluate utility of image morphometry in identifying DIG areas and to predict tumour grade. Materials and Methods. Image morphometry was used to analyze the following nuclear features of 30 DIGs and 10 controls (CG): major axis of nucleus (MAJX), minor axis of nucleus (MINX), nuclear area (NA), nuclear perimeter (NP), nuclear roundness (NR), nuclear density (ND), and percentage of total nuclear area (%TNA). Results. Statistically significant differences in all parameters, except NR, were observed between all groups, with strong positive correlation with tumour grade (r>0.7). The mean values were maximum for HGG and minimum for CG. For NR, the difference between CG/HGG was statistically significant, unlike CG/LGG and LGG/HGG. It was observed that NA distributions for CG were nearly Gaussian type with smaller range, while gliomas displayed erratic pattern with larger range. NA and NP exhibited strong positive correlation with ND. Conclusion. Image morphometry has immense potential in being a powerful tool to distinguish normal from neoplastic tissue and also to differentiate LGG from HGG cases, especially in tiny stereotactic biopsies.

2010 ◽  
Vol 19 (3-4) ◽  
Author(s):  
K. Černis ◽  
I. Eglitis ◽  
I. Wlodarczyk ◽  
J. Zdanavičius ◽  
K. Zdanavičius

AbstractA project for astrometric and photometric observations of asteroids at the Baldone Observatory is described. One of the most important results of the project is the discovery of 2008 OS9, a 600 meter asteroid of the NEO Apollo group. The results of its astrometric and photometric observations at the Molėtai and Baldone observatories are presented. From the brightness variation with the 0.27 mag amplitude, a rotation period of 8.430 ± 0.005 h is determined. Close approaches of the asteroid to Earth and Venus during the next millenium are predicted. The mean values of secular changes in the semi-major axis, eccentricity and inclination are computed with and without the Yarkovsky and YORP effects. A negative value of the difference between the value of semi-major axis computed with the Yarkovsky and YORP effects and without them, da/dt, may indicate retrograde rotation of the asteroid.


2004 ◽  
Vol 35 (2) ◽  
pp. 119-137 ◽  
Author(s):  
S.D. Gurney ◽  
D.S.L. Lawrence

Seasonal variations in the stable isotopic composition of snow and meltwater were investigated in a sub-arctic, mountainous, but non-glacial, catchment at Okstindan in northern Norway based on analyses of δ18O and δD. Samples were collected during four field periods (August 1998; April 1999; June 1999 and August 1999) at three sites lying on an altitudinal transect (740–970 m a.s.l.). Snowpack data display an increase in the mean values of δ18O (increasing from a mean value of −13.51 to −11.49‰ between April and August), as well as a decrease in variability through the melt period. Comparison with a regional meteoric water line indicates that the slope of the δ18O–δD line for the snowpacks decreases over the same period, dropping from 7.49 to approximately 6.2.This change points to the role of evaporation in snowpack ablation and is confirmed by the vertical profile of deuterium excess. Snowpack seepage data, although limited, also suggest reduced values of δD, as might be associated with local evaporation during meltwater generation. In general, meltwaters were depleted in δ18O relative to the source snowpack at the peak of the melt (June), but later in the year (August) the difference between the two was not statistically significant. The diurnal pattern of isotopic composition indicates that the most depleted meltwaters coincide with the peak in temperature and, hence, meltwater production.


1969 ◽  
Vol 60 (4) ◽  
pp. 579-585
Author(s):  
K. Schollberg ◽  
E. Seiler ◽  
J. Holtorff

ABSTRACT The urinary excretion of testosterone and epitestosterone by women in late pregnancy has been studied. The mean values of 22 normal women in pregnancy mens X are 12.9 ± 9.2 μg/24 h in the case of testosterone and 16.1 ± 16.2 μg/24 h in the case of epitestosterone. Both values do not differ significantly from those of non-pregnant females. The excretion values of mothers bearing a male foetus (17.3 ± 8.9 μg/24 h) are higher than those of mothers with a female foetus (6.4 ± 4.8 μg/24 h). The difference is statistically significant with P = 0.01.


2013 ◽  
Vol 24 (5) ◽  
pp. 482-486 ◽  
Author(s):  
Marili Doro Andrade Deonizio ◽  
Gilson Blitzkow Sydney ◽  
Antonio Batista ◽  
Roberto Pontarolo ◽  
Paulo Ricardo Bittencourt Guimarães ◽  
...  

This study evaluated the influence of apical patency, root filling removal technique and cleaning of the apical foramen, concerning the amount of debris extruded during root canal retreatment. Forty mandibular incisors were randomly assigned to 4 groups - GIM (n=10), GIIM (n=10), GIPT (n=10) and GIIPT (n=10), which were named according to leaving (I) or not (II) apical patency during canal preparation and filling removal technique (manual - M or ProTaper system - PT). After filling material removal, each specimen of each group had the apical foramen cleaned by sizes 15, 20 and 25 instruments, generating 12 subgroups: GIM15, GIM20, GIM25, GIIM15, GIIM20, GIIM25, GIPT15, GIPT20, GIPT25, GIIPT15, GIIPT20 and GIIPT25. Extruded filling debris was collected by a Milipore filtration system, an HV-durapore, 0.45 µm pore filter with a 25 mm diameter. The filters were weighed before and after the collection on an analytical scale (10–5 g), and the difference was calculated. The mean weight of extruded filling debris was analyzed statistically by Kruskal-Wallis and Friedman ANOVA tests (α=0.05). The mean values found in the groups (in mg) were: GIM (0.95±0.94), GIIM (0.47±0.62), GIPT (0.30±0.31) and GIIPT (0.32±0.44). There was no statistically significant difference among any of the groups or subgroups (p>0.05). ProTaper provided the smallest amount of extruded filling material, regardless of presence or absence of apical patency, followed by manual technique, without and with apical patency. Additional amounts of debris were collected during cleaning of the apical foramen, regardless of the instrument, presence/absence of patency or root filling removal technique.


2021 ◽  
Vol 9 (2) ◽  
pp. 3780-3784
Author(s):  
P.Vani ◽  
◽  
Sharan B Singh M ◽  

Introduction: Cigarette smoking is a prime risk factor for cardiovascular morbidity and mortality. Chronic smoking results in autonomic dysfunction leading to increased cardiovascular risk in smokers. The present study was planned to study the effect of smoking on the Cardiovascular Autonomic Functions among smokers. Materials and Methods: Fifty male subjects who were in the age group of 25 to 45 years. They were grouped into 25 smokers and 25 non-smokers. The participant subjects were selected among the staff members, residents and the patients from the routine OPD in SVIMS. Prior to study, they were informed about the procedure and the purpose of the study tests and written consents were obtained from them. The Cardiovascular Autonomic Function Tests were assessed by using a POLYGRAPH which was available in the department. Results and Conclusion: After applying the ‘t’-test for the difference between the two sample means, it was observed that there was a highly significant difference between the mean values of the BMI(i.e.p<0.01) and the para-sympathetic function tests among the smokers and the non – smokers(i.e.p<0.00). The Resting Heart Rate had significantly increased and the Deep breathing difference, the postural tachycardial index (Response to standing) and the Valsalva Ratio had significantly decreased in the smokers as compared to those in the non – smokers. After applying the ‘t’-test for the difference between the two sample means, it was observed that there was no significant difference between the mean values of the Postural hypotension test (i.e. p>0.05) and that there was a highly significant difference between the mean values of the Sustained handgrip test in the smokers and the non – smokers (i.e. p<0.00). KEY WORDS: Cardiovascular autonomic function tests, Smoking, Resting heart rate.


2017 ◽  
Vol 11 (1) ◽  
pp. 1041-1048 ◽  
Author(s):  
Mehmet Bekir Unal ◽  
Kemal Gokkus ◽  
Evrim Sirin ◽  
Eren Cansü

Objective: The main objective of this study is to evaluate the availability of lateral antebrachial cutaneous nerve (LACN) autograft for acute or delayed repair of segmented digital nerve injuries. Patients and Methods: 13 digital nerve defects of 11 patients; treated with interposition of LACN graft that harvested from ipsilateral extremity were included in the study. Mean follow up period was 35, 7 months. The mean time from injury to grafting is 53, 3 days. The results of the mean 2PDT and SWMT values of injured /uninjured finger at the end of follow up period were evaluated with Paired T test. The correlation between the defect length and the difference of 2PDT, SWMT values between the uninjured and injured finger at the end of follow up period; were evaluated with Pearson - correlation analysis. Results: The mean value of our 2PDT and SWMT results are ~5,923, ~3, 52, respectively in which can be interpreted between the normal and diminished light touch. The defect length and difference percentage of SWMT values is positively and significantly correlated statistically. Mean length of interposed nerve grafts was 18.5 mm. The age of the patient and the mean values of 2PDT and SWMT with the difference % of 2PDT and % of SWMT are not statistically correlated. Conclusion: Based on results regarding sensory regaining at recipient side and negligible sensory deficit at harvesting side, we suggest that lateral antebrachial cutaneous nerve might be a valuable graft option for digital nerve defects.


2007 ◽  
Vol 24 (2) ◽  
pp. 457-462 ◽  
Author(s):  
Lucélia Donatti ◽  
Edith Fanta

The Antarctic fish Trematomus newnesi (Boulenger, 1902) occurs from benthic to pelagic habitats, in seasonally and daily varied photic conditions that induce retinomotor movements. Fish were experimentally kept under constant darkness or light, and 12Light/12Dark for seven days. The retinomotor movement of the pigment epithelium was established through the pigment index, while that of the cones was calculated as the length of the myoid. The retinomotor movement of the pigment epithelium in T.newnesi,revealed that the adaptation to constant light occurred in the one hour of exposure, remaining constant for the next seven days. However, the adaptation to constant darkness, was slower. The difference between the mean values of the pigment indices in the time intervals of sampling was significant in the first hours of the experiment, and only after six hours they were not significant any more. The myoid of cones became elongated in darkness and contracted in light. In the experiments where T.newnesiwas exposed initially to 12 hours light followed by 12 hours darkness 12 was evidenced that the speed and intensity of the retinomotor movements was higher when darkness changed into light, than when light changed into darkness.


2020 ◽  
Vol 91 (1) ◽  
pp. 81-87
Author(s):  
Balaji Rajkumar ◽  
Ratna Parameswaran ◽  
Anantanarayanan Parameswaran ◽  
Devaki Vijayalakshmi

ABSTRACT Objectives To evaluate the tongue and oral cavity proper volume in pre- and post-bilateral sagittal split osteotomy (BSSO) patients, and to establish whether there was a correlation between them. Materials and Methods A retrospective study that evaluated 12 patients' pre- and post-surgical computed tomography records satisfying the inclusion criteria. Borders were defined for measurement of tongue and oral cavity proper volume. The volume assessment was carried out using 3D slice software. Results The mean difference of tongue volume was 5.7 ± 1.7 cm3, which showed high statistical significance. The mean difference of oral cavity proper volume (OCVP) was 6.9 ± 3.4 cm3 and indicated high statistical significance. A very strong positive correlation existed between pre- and post-surgical tongue volume. Positive correlation was also evident between pre and post - surgical OCVP. Medium positive correlation was noted when the difference between pre- and post-surgical tongue and OCVP were assessed. Conclusions There was a significant change in volume of tongue and oral cavity proper after BSSO advancement surgery. The space around the tongue, position of tongue, and maxillary and mandibular relationship influence the volume of tongue and oral cavity proper.


Author(s):  
Tega A Emurigho ◽  
Canice O.O Kabuo ◽  
Arinze N Ifegbo

The physical and engineering properties of fresh and dried tiger nut (Cyperus esculentus) were determined at moisture content of 41.20% and 16.40% on wet basis respectively. The mean values for the three principal axes (length, width and thickness) were 9.52mm, 8.16mm, and 8.16mm for fresh tiger nut and 9.14mm, 7.72mm and 8.03mm for dried tiger nut respectively, showing a decrease with decrease in moisture content and was significantly different at p?0.05. The mean values of the bulk density, true density and porosity of both fresh and dried tiger nut were 0.59g/cm3 , 0.97g/cm3 , 40.61 and 0.58g/cm3, 0.94g/cm3 , 40.35 respectively and were not significantly different at p?0.05. The mean angle of repose and coefficient of static friction over formica, stainless steel, glass and plywood surfaces of fresh tiger nut were 50.11o , 2.73, 2.45, 2.22 and 1.77 while that of dried tiger nut were 48.23o , 2.41, 2.03, 2.11 and 2.00 respectively. The mean rupture force increased with compression force of 90.08N on the major axis to 116.88N for fresh tiger nut and from 120.55N to 161.10N for dried tiger nut and were significantly different at p?0.05. These properties determined are necessary in the design and fabrication of hoppers, conveyor equipment and the force tiger nut can withstand before it is ruptured.


2017 ◽  
Vol 61 (4) ◽  
pp. 5-11 ◽  
Author(s):  
C. S. Ibe ◽  
S. O. Salami ◽  
N. Wanmi

Abstract As a sequel to the current advancement in ethology, this study was designed to provide information on the brain size of the African grasscutter at specific postnatal periods and to extrapolate these findings to the behaviour of the rodent in its natural habitat. Brain samples were extracted from African grasscutter neonates on postnatal day 6, juveniles on postnatal day 72 and adults on postnatal day 450 by basic neuro-anatomical techniques. The weight, volume and dimensions of the brain samples were determined in absolute and relative terms. Their encephalisation quotient was also computed. There was a very strong positive correlation between nose-rump length and brain length in the neonates. The relative brain weight of neonates, juveniles and adults were 3.84 ± 0.12 %, 2.49 ± 0.07 % and 0.44 ± 0.03 %, respectively. The differences were significant (P < 0.05). The encephalisation quotient of juveniles was 1.62 ± 0.03 while that of the adult was 0.49 ± 0.02. The difference was significant (P < 0.05). The results were extrapolated to the animal’s cognitive ability, and compared with other rodents. It was concluded that the juvenile African grasscutter may have higher cognitive ability than the adult rodent, thus, juveniles should be preferred in physiological studies of memory and cognition.


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