scholarly journals Fascia and Primo Vascular System

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Chun Yang ◽  
Yi-kuan Du ◽  
Jian-bin Wu ◽  
Jun Wang ◽  
Ping Luan ◽  
...  
Keyword(s):  
Vascular System ◽  
Circulatory System ◽  
Holistic Approach ◽  
The Body ◽  
Research Progress ◽  
Acupuncture Points ◽  
Cellular Mechanisms ◽  
Anatomical Basis ◽  
Functional Aspects ◽  
New Research

The anatomical basis for the concept of acupuncture points/meridians in traditional Chinese medicine (TCM) has not been resolved. This paper reviews the fascia research progress and the relationship among acupuncture points/meridians, primo vascular system (PVS), and fascia. Fascia is as a covering, with common origins of layers of the fascial system despite diverse names for individual parts. Fascia assists gliding and fluid flow and holds memory and is highly innervated. Fascia is intimately involved with nourishment of all cells of the body, including those of disease and cancer. The human body’s fascia network may be the physical substrate represented by the meridians of TCM. The PVS is a newly found circulatory system; recent increased interest has led to new research and new discoveries in the anatomical and functional aspects of the PVS. The fasciology theory provides new insights into the physiological effects of acupuncture needling on basic cellular mechanisms including connective tissue mechanotransduction and regeneration. This view represents a theoretical basis and means for applying modern biomedical research to examining TCM principles and therapies, and it favors a holistic approach to diagnosis and treatment.

scholarly journals Defining research priorities in dystonia

Neurology ◽  
2020 ◽  
Vol 94 (12) ◽  
pp. 526-537 ◽  
Author(s):  
Codrin Lungu ◽  
Laurie Ozelius ◽  
David Standaert ◽  
Mark Hallett ◽  
Beth-Anne Sieber ◽  
...  
Keyword(s):  
Research Priorities ◽  
Large Data ◽  
Therapeutic Interventions ◽  
Research Progress ◽  
Data Sets ◽  
Cellular Mechanisms ◽  
Research Technology ◽  
Current State ◽  
History Of ◽  
New Research

ObjectiveDystonia is a complex movement disorder. Research progress has been difficult, particularly in developing widely effective therapies. This is a review of the current state of knowledge, research gaps, and proposed research priorities.MethodsThe NIH convened leaders in the field for a 2-day workshop. The participants addressed the natural history of the disease, the underlying etiology, the pathophysiology, relevant research technologies, research resources, and therapeutic approaches and attempted to prioritize dystonia research recommendations.ResultsThe heterogeneity of dystonia poses challenges to research and therapy development. Much can be learned from specific genetic subtypes, and the disorder can be conceptualized along clinical, etiology, and pathophysiology axes. Advances in research technology and pooled resources can accelerate progress. Although etiologically based therapies would be optimal, a focus on circuit abnormalities can provide a convergent common target for symptomatic therapies across dystonia subtypes. The discussions have been integrated into a comprehensive review of all aspects of dystonia.ConclusionOverall research priorities include the generation and integration of high-quality phenotypic and genotypic data, reproducing key features in cellular and animal models, both of basic cellular mechanisms and phenotypes, leveraging new research technologies, and targeting circuit-level dysfunction with therapeutic interventions. Collaboration is necessary both for collection of large data sets and integration of different research methods.

scholarly journals Are Primo Vessels (PVs) on the Surface of Gastrointestine Involved in Regulation of Gastric Motility Induced by Stimulating Acupoints ST36 or CV12?

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaoyu Wang ◽  
Hong Shi ◽  
Hongyan Shang ◽  
Yangshuai Su ◽  
Juanjuan Xin ◽  
...  
Keyword(s):  
Gastric Motility ◽  
Electric Stimulation ◽  
Circulatory System ◽  
The Body ◽  
Inhibition Rate ◽  
Anatomical Basis ◽  
Significant Difference ◽  
Acupuncture Meridian ◽  
The Relationship ◽  
Stimulation Of

Previous studies showed primo vessels (PVs), which were referred to as Bonhan ducts (BHDs) and a part of circulatory system by Kim, located in different places of the body. The BHDs system was once considered as the anatomical basis of classical acupuncture meridian but not clearly identified by other investigators. In the present study, we tried to address the relationship between PVs and meridians through detecting the modulation of gastric motility by stimulating the PVs on the surface of stomach or intestine, as well as acupoints Zusanli (ST36) and Zhongwan (CV12). The results showed electric stimulation of the PVs had no effect on the gastric motility. While stimulating CV12 inhibited gastric motility significantly in PVs-intact and PVs-cut rats, there is no significant difference between the inhibition rate of the PVS-intact and the PVS-cut rats. Stimulating at ST36 increased gastric motility significantly in both the PVs-intact and the PVs-cut rats, yet there was no significant difference between the facilitation rate of the both groups. Taken together, the PVs on the surface of stomach or intestine did not mediate the regulation of gastric motility induced by stimulating at the acupoints ST36 or CV12.

scholarly journals Role of Ayurvedic Anticoagulant and Antioxidant Treatment in Covid-19

2021 ◽  
pp. 64-70
Author(s):  
Amrut.S. Salunke ◽  
Adarsh Ramkalap Sharma ◽  
Sonali Sunil Tadasarkar
Keyword(s):  
Respiratory System ◽  
Virus Disease ◽  
Circulatory System ◽  
Holistic Approach ◽  
The Body ◽  
Future Research ◽  
Antioxidant Treatment ◽  
New Approach ◽  
Corona Virus

Corona virus disease is caused by severe acute respiratory syndrome Corona virus 2[SARS-CoV-2] infections attacking multisystem of the human body at a time, of which respiratory system, immune system and circulatory system are most affected. The complications of the disease arise or it becomes more pronounced, after the cytokinine storm phase becomes established leading to hypercoagulative state affecting the circulatory and respiratory system. In Ayurveda, there is a holistic approach in treating the disease and the body as a whole. Drugs such as Haridra, Tulasi, Guduchi, Yashtimadhu, Twak, Triphala, Lavang, Maricha, Pippali etc and few Visha Dravyas like Langali, Dravanti etc can be used a single drug or a group of drugs with their phytochemical properties and active principles leading to delay and prevention of hyper coagulable states thereby preventing the cascade of complications caused by COVID, additionally having anti-inflammatory and immune-modulatory effect. Scientific research on these drugs may reveal a new approach for management and prevention of COVID related complications and can be a subject of future research interest.

The Blood Vascular System of Nephtys (Annelida, Polychaeta)

1956 ◽  
Vol s3-97 (38) ◽  
pp. 235-249
Author(s):  
R. B. CLARK
Keyword(s):  
Body Wall ◽  
Vascular System ◽  
Close Association ◽  
Circulatory System ◽  
Ventral Surface ◽  
Blood Stream ◽  
Neurosecretory Cells ◽  
The Body ◽  
Dorsal Vessel ◽  
The Brain

The four longitudinal vessels of the circulatory system of Nephtys californiensis are dorsal, sub-intestinal, and neural, the latter being paired. There is a complete longitudinal circulation; the dorsal vessel communicates with the sub-intestinal by way of the proboscidial circulation and with the neural by way of the circum-oral vessels. In each middle and posterior segment segmental vessels from each of the longitudinal trunks carry blood to and from the parapodia and body-wall. The segmental circulation is completed by a circum-intestinal vessel connecting the dorsal and subintestinal vessels in each segment and an intersegmental branch connecting the dorsal and sub-intestinal segmental vessels. A trans-septal branch of the neural segmental vessel communicates with the sub-intestinal segmental vessel. This arrangement is modified in anterior segments which house the muscular, eversible pharynx, and no blood-vessels cross the coelom except by running through the body-wall. On anatomical grounds and by comparison with other polychaetes it seems likely that segmental is subordinate to longitudinal circulation. There are no endothelial capillaries such as have been described in some other polychaetes; instead there are numerous blindending vessels the walls of which are composed of the same three layers as other vessels and which are probably contractile. The dorsal vessel, where it is in contact with the ventral surface of the supra-oesophageal ganglion, forms a plexus in close association with a modified part of the brain capsule and a special axonal tract within the ganglion. It is thought that by way of this ‘cerebro-vascular complex’, hormones produced in the neurosecretory cells of the brain pass into the blood-stream.

scholarly journals Review of Evidence Suggesting That the Fascia Network Could Be the Anatomical Basis for Acupoints and Meridians in the Human Body

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Yu Bai ◽  
Jun Wang ◽  
Jin-peng Wu ◽  
Jing-xing Dai ◽  
Ou Sha ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Biomedical Research ◽  
Human Body ◽  
Theoretical Basis ◽  
Holistic Approach ◽  
Acupuncture Points ◽  
Clinical Observations ◽  
Anatomical Basis ◽  
Scan Data

The anatomical basis for the concept of meridians in traditional Chinese medicine (TCM) has not been resolved. This paper reviews the evidence supporting a relationship between acupuncture points/meridians and fascia. The reviewed evidence supports the view that the human body's fascia network may be the physical substrate represented by the meridians of TCM. Specifically, this hypothesis is supported by anatomical observations of body scan data demonstrating that the fascia network resembles the theoretical meridian system in salient ways, as well as physiological, histological, and clinical observations. This view represents a theoretical basis and means for applying modern biomedical research to examining TCM principles and therapies, and it favors a holistic approach to diagnosis and treatment.

scholarly journals Anoikis Resistance: An Essential Prerequisite for Tumor Metastasis

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Yong-Nyun Kim ◽  
Kyung Hee Koo ◽  
Jee Young Sung ◽  
Un-Jung Yun ◽  
Hyeryeong Kim
Keyword(s):  
Cancer Cells ◽  
Cancer Metastasis ◽  
Epithelial Mesenchymal Transition ◽  
Vascular System ◽  
The Body ◽  
Membrane Microdomains ◽  
Cellular Mechanisms ◽  
Anoikis Resistance ◽  
Mesenchymal Transition ◽  
Technological Advances

Metastasis is a multistep process including dissociation of cancer cells from primary sites, survival in the vascular system, and proliferation in distant target organs. As a barrier to metastasis, cells normally undergo an apoptotic process known as “anoikis,” a form of cell death due to loss of contact with the extracellular matrix or neighboring cells. Cancer cells acquire anoikis resistance to survive after detachment from the primary sites and travel through the circulatory and lymphatic systems to disseminate throughout the body. Because recent technological advances enable us to detect rare circulating tumor cells, which are anoikis resistant, currently, anoikis resistance becomes a hot topic in cancer research. Detailed molecular and functional analyses of anoikis resistant cells may provide insight into the biology of cancer metastasis and identify novel therapeutic targets for prevention of cancer dissemination. This paper comprehensively describes recent investigations of the molecular and cellular mechanisms underlying anoikis and anoikis resistance in relation to intrinsic and extrinsic death signaling, epithelial-mesenchymal transition, growth factor receptors, energy metabolism, reactive oxygen species, membrane microdomains, and lipid rafts.

scholarly journals Мальформации как нарушение фрактальной структуры кровеносной системы организма

2020 ◽  
Vol 90 (9) ◽  
pp. 1506
Author(s):  
В. Антонов ◽  
П. Ефремов
Keyword(s):  
Heat Transfer ◽  
Blood Flow ◽  
Life Support ◽  
Vascular System ◽  
Circulatory System ◽  
Flow Simulation ◽  
Simulation Software ◽  
Heat Fluxes ◽  
The Body ◽  
Model Base

The article contains a description of mathematical models, the bases of which is the representation of the body circulatory system as a multifractal object. As examples, we consider the solution of two problems. The first issue is related to the normal state of the body’s life support system, namely, heat transfer in human skin. The model base is the equations of hydrodynamics and heat transfer. Quantitative results of calculating heat fluxes in three layers of the dermis are presented. The second issue deals with a violation of fractality due to the presence of arteriovenous malformation in the brain vascular system. The SolidWorks 2017 Flow Simulation software product serves as the basis for the implementation of a blood flow model in the presence of malformation. As a result of the simulation, data on the velocities and blood flow in the vessels were obtained for various cases of malformations.

Chōng $$ an Ancient Chinese Description of the Vascular System?

2014 ◽  
Vol 32 (3) ◽  
pp. 279-285 ◽  
Author(s):  
Vivien Shaw
Keyword(s):  
Internal Medicine ◽  
Blood Vessels ◽  
Human Body ◽  
Vascular System ◽  
Vena Cava ◽  
Vascular Anatomy ◽  
The Body ◽  
Acupuncture Points ◽  
Chinese Texts ◽  
The Ancient Chinese

The objectives of this research are, first, to establish if the extraordinary acupuncture meridian known as Chōng $$ Penetrating Vessel or Sea of Blood, is in essence a description of certain macroscopic parts of the underlying vascular system and, second, by extension, to show that it is likely that cadaveric dissection would have been used as a tool to arrive at this understanding. Generally accepted scholarly opinion holds that the ancient Chinese rarely used dissection in order to explore the anatomy of the human body, and that the meridians are therefore invisible metaphysical structures corresponding to lines drawn on the body. However, the seminal text, ‘The Yellow Emperor's Classic of Internal Medicine’, describes using palpation to examine the living and dissection to examine the dead. This implies that the original authors of these texts were observing physical structures visible to the naked eye. Dissection has therefore been used to compare the descriptions of the Chōng meridian in ‘The Yellow Emperor's Classic of Internal Medicine’ with the vascular anatomy of the human body. Fifteen acupuncture points located on various different ordinary meridians but bearing the same name, Chōng $$ were also examined to see if they bore any relationship to the vascular system. The dissections clearly show that the Chōng meridian correlates to certain main blood vessels in the body, in particular the vena cava. Similarly, most Chōng acupuncture points have a strong correspondence with blood vessels, marking terminal arteries on the hands, feet and forehead and anastomoses on the face, body and feet. These findings strongly suggest that the ancient Chinese texts relating to this meridian are likely to have been a ‘description’ of the vascular system. Furthermore, the ancient Chinese apparently had a high degree of anatomical skill in the practice of dissection and acute powers of observation.

scholarly journals Analytical Method of Human Systemic and Global Circulation

2021 ◽  
pp. 13-33
Author(s):  
Francis Egenti Nzerem ◽  
Eucharia C. Nwachukwu
Keyword(s):  
Vascular System ◽  
Voltage Drop ◽  
Circulatory System ◽  
The Body ◽  
Topological Constraints ◽  
Global Circulation ◽  
Cardio Vascular ◽  
Electrical Impulses ◽  
In Virtue Of ◽  
Flow Circuit

Abstract The human circulatory system is one of the admirable rhythms of nature. The heart and the vasculature are constitutive structures. The vasculature consists of arterial and venous appurtenances which are arranged in an idealized network capable of enhancing circulation. The crux of this study is the representation of the cardiovascular system as a network in which electrical constraints apply. As a network, the system is amenable to graph analytic treatment; as edge-nodal parameters ensue, topological constraints apply. In virtue of cardiac auto-rhythmicity, electrical impulses are driven through the vessels to the body cells. As a rule, the vessels must elicit a modicum of resistance. This work weaponized the elements of graph theory and electrical properties of the heart in elucidating the flow mechanism associated with the cardio-vascular system. The voltage drop across the connecting vessels (idealized as wires) was carefully depicted and analyzed by the method of matrices. When the cardiac function is within physiological definition a vascular compartment may be a liability in the event of poor circulation. Therefore the knowledge of vascular resistive capacities, which this work portrayed, is a sine-qua-non to the assessment of flow integrity of the system under consideration. MSC 2010 No.: 05C21, 92C42, 92B25. Keywords: Cardiovascular, Network, Matrices, Flow, Circuit, Edges and Nodes, Wave propagation, Bifurcation.

scholarly journals The size of the aorta in warm-blooded animals and its relationship to the body weight and to the surface area expressed in a formula

1912 ◽  
Vol 86 (584) ◽  
pp. 39-56 ◽  
Keyword(s):  
Body Weight ◽  
Vascular System ◽  
Circulatory System ◽  
The Body ◽  
Accurate Data ◽  
Quantitative Correlation ◽  
Pathological Conditions ◽  
Cardio Vascular ◽  
The Individual ◽  
Satisfactory Manner

In recent years it has become increasingly evident that many of the most important problems of physiology and of experimental pathology cannot be investigated in a satisfactory manner until accurate data have been made available regarding the quantitative differences which are exhibited by the organs, tissues, and fluids of the body in normal animals of different species and of varying weights. Results obtained with animals of any given weight cannot be applied, even within one and the same species, to yield con­clusions regarding animals of a different weight until it has been determined with precision how the various organs and tissues of the body are related to the size of the individual. Moreover, it will not be possible to compare one species with another, or to apply the results deduced from any given species to any other species of animal, until we can establish the existence of some kind of quantitative correlation between the measurements in different species. That this will prove to be possible seems likely from an examination of the results already obtained by us in studying the various factors which influence the circulatory system and determine the size of the heart (1). In connection with our study of the blood and cardio-vascular system under normal and pathological conditions, it was shown that the blood volume of normal animals of any given species is proportional to their body surface, and follows the formula B = W n / k , where k is a constant for the species and n is approximately 0.70-0.72 (2), (3). Accordingly it became of interest, in view of the theories which have been put forward regarding the volume of the blood and the size of the aorta in chlorotic conditions, to endeavour to determine how the size of the aorta is related to the weight of the individual in any given species of animal.

Sign in / Sign up

Export Citation Format

Share Document