HeucheraCreme Brulee and Mahogany Medicinal Value under Water Stress and Oligosaccharide (COS) Treatment

Food borne pathogens cause serious human illnesses and diseases and their control using natural bioactive compounds becomes essential for the progress of agricultural and food industries. Developing novel tools to enhance the medicinal values of traditional horticultural medicinal crops is one of the promising methods for achieving food borne pathogens control. In this study, oligosaccharide water solutions were applied toHeucheraCreme Brulee and Mahogany subjected to a normal irrigation interval (2 days) or to prolonged irrigation intervals (6 days) for 6 weeks. Plant morphological, physiological, and metabolic markers associated with the bioactivity of leaf extracts against selected microbes. Oligosaccharide-treated plants showed significant increases in all morphological parameters during normal and prolonged irrigation intervals as compared to those of the controls. Morphological improvement associated with a significant increase in chlorophyll, carbohydrates, proline, K, Ca, phenols, and free and total ascorbate and antioxidants. Superoxide dismutase, catalase, and ascorbate peroxidase activities were higher, while H2O2accumulated to a lower extent in oligosaccharide-treated plants. These morphological and metabolic changes associated with increased antibacterial and antifungal activities of leaf extracts and their activities were comparable to antibiotics and antifungal agents (minimum inhibitory concentrations values were 0.5 -0.20 mg−1mL for bacteria and 0.08 -0.20 mg−1mL for fungi in Mahogany). The application of oligosaccharide and/or water stress might be of great value for producing natural bioactive compounds for food borne pathogens control.

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In vitro Antioxidant and Antimicrobial Effects of Ceratostigma plumbaginoides

Natural Product Communications ◽

10.1177/1934578x1601101010 ◽

2016 ◽

Vol 11 (10) ◽

pp. 1934578X1601101 ◽

Cited By ~ 2

Author(s):

Hosam O. Elansary ◽

Kowiyou Yessoufou ◽

Eman A. Mahmoud ◽

Krystyna Skalicka-Woźniak

Keyword(s):

Bioactive Compounds ◽

Diethyl Ether ◽

Ornamental Plants ◽

Antioxidant Properties ◽

Antimicrobial Activities ◽

Leaf Extracts ◽

Antifungal Activities ◽

Antibacterial And Antifungal Activities ◽

Antibacterial And Antifungal

Bioactive compounds, including phenols, flavonoids, and tannins, were quantified in leaves, stems and roots of methanol, n-butanol, diethyl ether and n-hexane extracts of Ceratostigma plumbaginoides Bunge. (Plumbaginaceae) ornamental plants. The antioxidant capacity was measured by the DPPH and linoleic acid assays. The total bioactive compounds, as well as the antioxidant capacities, were the highest in the leaves compared with stems and roots. The methanolic, n-butanol, diethyl ether and n-hexane leaf extracts varied in their antibacterial and antifungal activities. In general, the most sensitive bacterium to leaf extracts was Bacillus cereus and the most resistant was Staphyllococcus aureus, while the most sensitive fungus was Aspergillus flavus and the most resistant one was Penicillium ochrochloron. As the methanolic leaf extract was the most active, it was subjected to column chromatography and two compounds were isolated and identified as 1 (5-hydroxy-2-methyl-1,4-naphthoquinone / plumbagin) and 2 (3,3′-biplumbagin). Compounds 1 and 2 showed the highest antibacterial and antifungal activities compared with other extracts tested. The MIC and MBC values for the most active compound 1 were in the range of 0.001 – 0.09 and 0.004 – 0.21 mg mL−1, while MIC and MFC were determined as 0.001 – 0.11 and 0.002 – 0.19 mg mL−1, respectively. The isolated compounds and leaf extracts showed also equal or higher antimicrobial activities compared with antibiotics/commercial reagents which indicate that the plant might be useful for drug development. This is the first report on the antibacterial and antifungal activities, as well as the antioxidant properties of the tested plant parts and isolated compounds.

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Valorization of Sicanaodorifera (Vell.) Naudin Epicarp as a Source of Bioactive Compounds: Chemical Characterization and Evaluation of Its Bioactive Properties

Foods ◽

10.3390/foods10040700 ◽

2021 ◽

Vol 10 (4) ◽

pp. 700

Author(s):

Bianca R. Albuquerque ◽

Maria Inês Dias ◽

Carla Pereira ◽

Jovana Petrović ◽

Marina Soković ◽

...

Keyword(s):

Phenolic Compounds ◽

Bioactive Compounds ◽

Food Additives ◽

Chemical Characterization ◽

Dry Weight ◽

Bioactive Molecules ◽

High Concentration ◽

Minimal Inhibitory Concentrations ◽

Antibacterial And Antifungal Activities ◽

Antibacterial And Antifungal

Fruit bio-residues can be interesting for the recovery of bioactive molecules, such as phenolic compounds, tocopherols, vitamins, among others. These compounds can be targeted at the food industry and used for the development of functional foods or as food additives. In some cases, fruit epicarps are converted into by-products with non-commercial value, and generally, these fruit parts have a higher content in bioactive compounds than the fruit pulp. From this perspective, S. odorifera, a Brazilian fruit, has an inedible epicarp that could be explored to obtain biological compounds. Therefore, the aims of this study were to evaluate the chemical composition and the antioxidant, anti-proliferative, anti-inflammatory, and antimicrobial bioactivities of this by-product. S. odorifera epicarp showed a total of four organic acids, four phenolic compounds, highlighting the high concentration of anthocyanins (24 ± 1 mg/g dry weight (dw)) and high content of tocopherols (366 ± 2 mg/100 g dw). The hydroethanolic extract showed considerable antioxidant activity (EC50 values of 48.2 ± 0.5 and 27 ± 1 µg/mL for TBARS and OxHLIA assays, respectively), as also antibacterial and antifungal activities (minimal inhibitory concentrations (MICs) ≤ 2.2 mg/mL). The results obtained in this study suggest that Sicana odorifera epicarp represents a reliable option for the development of novel natural-based colorants with functional/bioactive proprieties.

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Analysis and the potential applications of essential oil and leaf extracts of Silene armeria L. to control food spoilage and food-borne pathogens

European Food Research and Technology ◽

10.1007/s00217-008-0885-z ◽

2008 ◽

Vol 227 (6) ◽

pp. 1613-1620 ◽

Cited By ~ 11

Author(s):

Vivek K. Bajpai ◽

Nguyen Thi Dung ◽

O. Jun Kwon ◽

Sun Chul Kang

Keyword(s):

Essential Oil ◽

Food Spoilage ◽

Leaf Extracts ◽

Food Borne Pathogens ◽

Food Borne ◽

Control Food ◽

Potential Applications ◽

Silene Armeria

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Bioactive Compounds and its Autochthonous Microbial Activities of Extract and Clove Oil (Syzygium aromaticum L.) on Some Food Borne Pathogens

Asian Journal of Biological Sciences ◽

10.3923/ajbs.2011.35.43 ◽

2010 ◽

Vol 4 (1) ◽

pp. 35-43 ◽

Cited By ~ 10

Author(s):

B. Joseph ◽

S. Sujatha

Keyword(s):

Bioactive Compounds ◽

Syzygium Aromaticum ◽

Clove Oil ◽

Microbial Activities ◽

Food Borne Pathogens ◽

Food Borne

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BIOACTIVE COMPOUNDS, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF TWO Cirsium SPECIES

Acta Scientiarum Polonorum Hortorum Cultus ◽

10.24326/asphc.2019.5.21 ◽

2019 ◽

Vol 18 (5) ◽

pp. 213-221 ◽

Cited By ~ 1

Author(s):

Dumrul Gulen ◽

Temine Sabudak ◽

Hakime H. Orak ◽

Hilmican Caliskan ◽

Merve Ozer

Keyword(s):

Antibacterial Activity ◽

Antifungal Activity ◽

Bioactive Compounds ◽

Antifungal Activities ◽

E Coli ◽

Inhibition Effect ◽

Antibacterial And Antifungal Activities ◽

Hexane Extracts ◽

Phytochemical Compounds ◽

Antibacterial And Antifungal

In the GC-MS analysis, 81 bioactive phytochemical compounds were identified in the hexane extracts of Cirsium creticum and Cirsium italicum. Terpenoids constituted the main fractions of C. italicum (70.95 %) while hydrocarbons were most abundant compounds of C. creticum (41.11 %). The antibacterial activity and antifungal activity of extracts from two Cirsium species was tested by using microdilution methods. According to the results of antibacterial activity, highest inhibition effect of C. creticum was found on B. subtilis, E. coli and P. aeruginosa. The highest inhibition effect of C. italicum was found on B. subtilis. In the results of antifungal activity, highest inhibition effect of C. creticum was found on P. chrysogenum and highest inhibition effect of C. italicum was found on C. krusei. The present work is the first report on hexane extracts compounds of two Cirsium species as well as the antibacterial and antifungal activities.

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Antibacterial and antifungal activities of leaf extracts of Phyllanthus amaru Schum and Thonn.

Journal of Pharmacognosy and Phytotherapy ◽

10.5897/jpp2013.0261 ◽

2017 ◽

Vol 9 (1) ◽

pp. 6-10 ◽

Cited By ~ 2

Author(s):

C.T. Senjobi ◽

A. O. Ettu ◽

C.O. Otujo

Keyword(s):

Leaf Extracts ◽

Antifungal Activities ◽

Antibacterial And Antifungal Activities ◽

Antibacterial And Antifungal

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Caralluma europaea (Guss.) N.E.Br.: Anti-Inflammatory, Antifungal, and Antibacterial Activities against Nosocomial Antibiotic-Resistant Microbes of Chemically Characterized Fractions

Molecules ◽

10.3390/molecules26030636 ◽

2021 ◽

Vol 26 (3) ◽

pp. 636

Author(s):

Fatima Ez-Zahra Amrati ◽

Mohammed Bourhia ◽

Hamza Saghrouchni ◽

Meryem Slighoua ◽

Andriy Grafov ◽

...

Keyword(s):

Bioactive Compounds ◽

Chemical Characterization ◽

Antibacterial Activities ◽

Antibiotic Resistant ◽

Traditional Medicines ◽

Gram Positive Bacteria ◽

Antibacterial And Antifungal Activities ◽

The Family ◽

Anti Inflammatory ◽

Antibacterial And Antifungal

Caralluma europaea (Guss.) N.E.Br.: (C. europaea) is a wild medicinal plant belonging to the family Apocynaceae. It is commonly used in traditional medicines for treating several diseases. The present work aims to evaluate the anti-inflammatory, antibacterial, and antifungal potentials of C. europaea fractions including hydro ethanol (ET CE), n-butanol (But CE), and polyphenol (Poly CE). The chemical composition of hydroethanol, n-butanol, and polyphenol-rich fractions from C. europaea were determined using GC-MS after silylation. The anti-inflammatory effect of hydroethanol, n-butanol, and polyphenol-rich fractions was studied by carrageenan-induced paw edema. Antibacterial and antifungal activities of hydroethanol, n-butanol, and polyphenol-rich fractions against Gram-positive bacteria, Gram-negative bacteria, and yeasts were assessed using the disc diffusion and micro-dilution assays. The findings of the chemical characterization affirmed the presence of interesting bioactive compounds in C. europaea fractions. The polyphenol-rich fraction was the best inhibitor of edema by75.68% after 6 h of treatment. The hydroethanol fraction was the most active against both bacteria and yeasts. This study contributes to society as it provides potential bioactive compounds in C. europaea extract, which may help in fighting nosocomial antibiotic-resistant microbes.

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Antimicrobial activities of secondary metabolites of endophytic fungi isolated from Catharanthus roseus

Journal of Health Sciences ◽

10.17532/jhsci.2017.421 ◽

2017 ◽

Vol 7 (1) ◽

pp. 15-22 ◽

Cited By ~ 4

Author(s):

Mark O. Akpotu ◽

Peter M. Eze ◽

Chika C. Abba ◽

Blessing O. Umeokoli ◽

Charles U. Nwachukwu ◽

...

Keyword(s):

Secondary Metabolites ◽

Bioactive Compounds ◽

Endophytic Fungi ◽

Catharanthus Roseus ◽

High Performance ◽

Antimicrobial Activities ◽

Antibacterial And Antifungal Activities ◽

Rice Medium ◽

Antibacterial And Antifungal ◽

Promising Source

Introduction: Recently, several endophytes have been shown to possess the potentials to synthesize novel bioactive compounds that have found use for drug discovery. We isolated endophytic fungi associated with Catharanthus roseus collected from the river banks of Amassoma in Southern Nigeria, and identified some of their bioactive secondary metabolites. Methods: The fungi were subjected to solid-state fermentation on rice medium and the metabolites were extracted using ethyl acetate. The fungal crude extracts were screened for antimicrobial activity and were also subjected to high-performance liquid chromatography-diode-array detection (HPLC-DAD) analysis for the identification of the bioactive compounds. Results: The fungal extracts showed both antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.0625 to 1 mg/mL. The HPLC-DAD analysis of the extracts suggested the presence of citreoisocoumarin, citreoisocoumarinol, questinol, hydroxyemodin, acropyrone, methyl 2-(4-hydroxyphenyl) acetate, nigricinol, and cladosporin. Conclusion: The results of this study suggest that endophytic fungi associated with C. roseus could be a promising source of novel bioactive compounds with pharmaceutical and industrial importance.

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