scholarly journals A Systematic Review of Real-Time Medical Simulations with Soft-Tissue Deformation: Computational Approaches, Interaction Devices, System Architectures, and Clinical Validations

2020 ◽  
Vol 2020 ◽  
pp. 1-30 ◽  
Author(s):  
Tan-Nhu Nguyen ◽  
Marie-Christine Ho Ba Tho ◽  
Tien-Tuan Dao

Simulating deformations of soft tissues is a complex engineering task, and it is even more difficult when facing the constraint between computation speed and system accuracy. However, literature lacks of a holistic review of all necessary aspects (computational approaches, interaction devices, system architectures, and clinical validations) for developing an effective system of soft-tissue simulations. This paper summarizes and analyses recent achievements of resolving these issues to estimate general trends and weakness for future developments. A systematic review process was conducted using the PRISMA protocol with three reliable scientific search engines (ScienceDirect, PubMed, and IEEE). Fifty-five relevant papers were finally selected and included into the review process, and a quality assessment procedure was also performed on them. The computational approaches were categorized into mesh, meshfree, and hybrid approaches. The interaction devices concerned about combination between virtual surgical instruments and force-feedback devices, 3D scanners, biomechanical sensors, human interface devices, 3D viewers, and 2D/3D optical cameras. System architectures were analysed based on the concepts of system execution schemes and system frameworks. In particular, system execution schemes included distribution-based, multithread-based, and multimodel-based executions. System frameworks are grouped into the input and output interaction frameworks, the graphic interaction frameworks, the modelling frameworks, and the hybrid frameworks. Clinical validation procedures are ordered as three levels: geometrical validation, model behavior validation, and user acceptability/safety validation. The present review paper provides useful information to characterize how real-time medical simulation systems with soft-tissue deformations have been developed. By clearly analysing advantages and drawbacks in each system development aspect, this review can be used as a reference guideline for developing systems of soft-tissue simulations.

Author(s):  
Christian Willberg ◽  
Harald Berger ◽  
Ulrich Gabbert

Endoscopic techniques require small perforation holes only as entries for optical and surgical instruments; such enabling the treatment of injuries with a minimized damage of the surrounding health tissue. But the surgeon has to operate in a 3D domain by looking at a distorted 2D image at the screen. It is well known, that a good surgeon needs a continuous training to perform such operations reliable in a top quality. To overcome the high costs and tight ethical restrictions of animal based education and training has result in an increasing development and application of virtual surgery simulators [1]. One of the main issues of surgery simulators is to ensure simultaneously the real time performance of the device, the high-level image representation and an acceptable force-feedback behavior. The basics of such simulators are mathematical models of the involved soft tissues, which have to perform in a realistic physical manner, with dynamic nonlinear large deformations, including the interaction of the different constituents (instrument/organ, organ/organ, organ by itself, cutting, bleeding etc). In the paper the focus is on realistic organ models and the realization of a fast contact search and reaction algorithm.


2021 ◽  
pp. 1-16
Author(s):  
Dan Luo ◽  
Yu Zhang ◽  
Jia Li ◽  
Jisheng Li

Virtual surgery robot can accurately modeling of surgical instruments and human organs, and realistic simulation of various surgical phenomena such as deformation of organic tissues, surgery simulation system can provide operators with reusable virtual training and simulation environment. To meet the requirement of virtual surgery robot for the authenticity and real-time of soft tissue deformation and surgical simulation in liver surgery, a new method is proposed to simulate the deformation of soft tissue. This method combines the spring force, the external force of the system, and the constraint force produced by the constraint function of the position-based dynamics. Based on the position-based dynamics, an improved three-parameter mass-spring model is added. In the calculation of the elastic force, the nonlinearity and viscoelasticity of the soft tissue are introduced, and the joint force of the constraint projection process and the constraint force of the position-based dynamics is used to modify mass points movement. The method of position-based dynamics based on biological characteristics, not only considers the biomechanical properties of biological soft tissue as an organic polymer such as viscoelasticity, nonlinearity, and incompressibility but also retains the rapidity and stability of the position based dynamic method. Through the simulation data, the optimal side length of tetrahedral mesh in the improved three-parameter model is obtained, and the physical properties of the model are proved. The real-time simulation of the liver and other organs is completed by using the Geomagic touch force feedback device, which proves the practicability and effectiveness of this method.


2020 ◽  
Vol 54 (4) ◽  
pp. 289-296
Author(s):  
Adeeba Ali ◽  
Anil K. Chandna ◽  
Anshul Munjal

Background: Concerns about the accuracy and reliability of soft tissue landmarks using two-dimensional (2D) and three-dimensional (3D) imaging. Objective: The aim of the systematic review is to estimate accuracy and reliability of soft tissue landmarks with 2D imaging and 3D imaging for orthodontic diagnosis planning and treatment planning purposes. Data Sources: Electronic database search was performed in MEDLINE via PubMed, Embase via embase.com, and the Cochrane library website. Selection Criteria: The data were extracted according to two protocols based on Centre for Evidence-Based Medicine (CEBM) critical appraisal tools. Next, levels of evidence were categorized into three groups: low, medium, and high. Data Synthesis: Fifty-five publications were found through database search strategies. A total of nine publications were included in this review. Conclusion According to the available literature, 3D imaging modalities were more accurate and reliable as compared to 2D modalities. Cone beam computed tomography (CBCT) was considered the most reliable imaging tool for soft tissues.


Author(s):  
Khrystyna Zhurakivska ◽  
Giuseppe Troiano ◽  
Marco Montella ◽  
Lorenzo Lo Muzio ◽  
Luca Fiorillo ◽  
...  

Malignant fibrous histiocytoma is one of the most common soft tissue sarcomas in adults. It occurs only occasionally in oral soft tissues, and knowledge about its characteristics is based on a limited number of cases reported in the literature. Malignant fibrous histiocytoma belongs to the group of soft tissue sarcomas and makes up less than 10% of soft tissue sarcomas. For therapeutic purposes, complete exeresis of the lesion (macroscopic and microscopic) is performed because they have frequent recurrences. As for complementary therapy in addition to surgery, neither radiotherapy nor chemotherapy have been shown to reduce the risk of death related to the disease. Often patients complain of a swelling that grows in a short period of time. It is quite common for patients to report trauma in the area, which is not the cause, but rather the event that allows diagnosis. The mass usually does not cause pain unless it compresses an adjacent nerve structure. The aim of this study is to systematically review the scientific literature in order to identify the most recent studies concerning malignant fibrous histiocytomas localized in oral soft tissues and report their main data. The main outcomes of this study concern the immunohistochemical, molecular, and clinical aspects of this pathology. A systematic review of articles in the electronic databases pubmed, Scopus, and Web of Science was performed. After the selection process, 11 studies met the inclusion criteria and were included in the review. The mean age of the patients was 50.8 years old. The lesions affected various parts of the oral cavity, showing predominantly storiform–pleomorphic patterns. All cases except one were treated with surgical resection and radiation therapy. Although some data emerged from this review, they remain limited to a few case reports. Further studies are necessary in order to standardize the approach to patients affected by oral malignant fibrous histiocytoma (MFH).


2016 ◽  
Vol 16 (08) ◽  
pp. 1640016 ◽  
Author(s):  
JING YANG ◽  
LINGTAO YU ◽  
LAN WANG ◽  
HONGYANG LI ◽  
QI AN

In recent years, virtual surgical simulation has been one of the hot direction of digital medical research, it is mainly used in teaching, training, diagnosis, preoperative planning, rehabilitation and modeling and analysis of surgical instruments. The modeling of soft tissue of human organs is the basis to realize the virtual surgical simulation. The quasi-linear viscoelastic (QLV) theory has been proposed by Fung, and it was widely used for modeling the constitutive equation of soft tissues. The purpose of this study is to determine the mechanical characterization of the liver soft tissue based on the PHANTOM Omni Haptic devices. Five parameters are included in the constitutive equation with QLV theory, which must be determined experimentally. The specimens were obtained from fresh porcine liver tissues in vitro. The liver tissues were cut into 14[Formula: see text]mm[Formula: see text][Formula: see text][Formula: see text]14[Formula: see text]mm[Formula: see text][Formula: see text][Formula: see text]14[Formula: see text]mm cubes. Two types of unconfined compression tests were performed on cube liver specimens. Puncture tests were performed on the complete liver. The material parameters of the QLV constitutive equation were obtained by fitting the experimental data. These parameters will provide the references for the computational modeling of the liver in the virtual surgical simulation.


2015 ◽  
Vol 41 (5) ◽  
pp. 612-619 ◽  
Author(s):  
André Barbisan ◽  
Cintia Santana Dias ◽  
Paula Furlan Bavia ◽  
Vitor Marques Sapata ◽  
João Batista César-Neto ◽  
...  

The aim of the present study was to conduct a systematic review of the literature to compare soft tissue aspects of immediate and delayed implant placement in esthetic areas. This review of literature was conducted in the following databases: MEDLINE (PubMed), Lilacs, Scielo, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL). For those studies that met the inclusion/exclusion criteria, the results were analyzed and summarized according to the treatment protocol used for implant placement. The primary parameters taken into consideration were papilla level (PL) and marginal mucosa level (MML) around implants. Four randomized controlled trials (RCT) were selected for analysis, but all were deemed as being of poor quality according to quality assessment. No studies reported any statistically significant differences concerning the soft tissue esthetic parameters analyzed around immediate or delayed implants at any follow-up periods reported. However, PL results seemed to be more reliable than were MML results, due to the PL standardization of the method of analysis, which showed a tendency for poorer results around immediately placed implants. In conclusion, although the results are based on only a few poor quality RCTs, both treatment options for implant placement demonstrated similar outcomes in the esthetic area, especially when PL was considered.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Benedictine Yen Chen Khor ◽  
James Woodburn ◽  
Lisa Newcombe ◽  
Ruth Barn

Abstract Background Diabetes mellitus is associated with changes in soft tissue structure and function. However, the directionality of this change and the extent to which either tissue thickness or stiffness contributes to the pathogenesis of diabetes-related foot ulcerations is unclear. Hence, this systematic review aims to summarise the existing evidence for soft tissue structural differences in the feet of people with and without diabetes. Methods In compliance with MOOSE and PRISMA guidelines, AMED, CINAHL, MEDLINE, ProQuest Health & Medical Collection, ProQuest Nursing & Allied Health Database, and Web of Science electronic databases were systematically searched for studies published from database inception until 1st October 2020 [Prospero CRD42020166614]. Reference lists of included studies were further screened. Methodological quality was appraised using a modified critical appraisal tool for quantitative studies developed by McMaster University. Results A total of 35 non-randomised observational studies were suitable for inclusion. Within these, 20 studies evaluated plantar tissue thickness, 19 studies evaluated plantar tissue stiffness, 9 studies evaluated Achilles tendon thickness and 5 studies evaluated Achilles tendon stiffness outcomes. No significant differences in plantar tissue thickness were found between people with and without diabetes in 55% of studies (11/20), while significantly increased plantar tissue stiffness was found in people with diabetes in 47% of studies (9/19). Significantly increased Achilles tendon thickness was found in people with diabetes in 44% of studies (4/9), while no significant differences in Achilles tendon stiffness were found between people with and without diabetes in 60% of studies (3/5). Conclusions This systematic review found some evidence of soft tissue structural differences between people with and without diabetes. However, uncertainty remains whether these differences independently contribute to diabetes-related foot ulcerations. The heterogeneity of methodological approaches made it difficult to compare across studies and methodological quality was generally inadequate. High-quality studies using standardised and validated assessment techniques in well-defined populations are required to determine more fully the role of structural tissue properties in the pathogenesis of diabetes-related foot ulcerations.


2019 ◽  
Vol 14 (4) ◽  
pp. 040802 ◽  
Author(s):  
Brandaan G. R. Zigterman ◽  
Casper Van den Borre ◽  
Annabel Braem ◽  
Maurice Y. Mommaerts

Author(s):  
Adeeb Sidani ◽  
J. Duarte ◽  
J. Santos Baptista ◽  
Mário Vaz ◽  
João Poças Martins ◽  
...  

Building Information Modelling (BIM) is used in construction projects to improve efficiency. In general, it improves project management and monitoring, reduces time and costs, strengthens collaboration among stakeholders, and reduces risks and injuries. Sensor technologies with various functionalities are being implemented in the construction site. Technologies such as tracking workers and transmitting real-time site inspections to support the BIM tools in various fields are being used. To evaluate sensor technologies’ usability and effectiveness in Architecture, Engineering, Construction and Operations (AECO) sector, a literature review adapting PRISMA Statement is proposed. Consequently, this document represents a complementary manuscript as a PRISMA Protocol (PRISMA-P). Relevant articles are collected from top electronic databases in the construction field. This review aims to investigate the sensor connected BIM models and the technologies being utilised in the AECO sector, investigating the targeted groups, construction field, and the system architectures being used. Furthermore, the study will examine the case studies of the implemented sensors to evaluate each technology’s effectiveness. Finally, the reliability of the tools and future proposals is projected.


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