scholarly journals Human Uterine Biopsy: Research Value and Common Pitfalls

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Alison Maclean ◽  
Areege Kamal ◽  
Meera Adishesh ◽  
Rafah Alnafakh ◽  
Nicola Tempest ◽  
...  
Keyword(s):  
Current Understanding ◽  
Future Research ◽  
Human Uterus ◽  
Oncology Research ◽  
Human Fertility ◽  
Different Types ◽  
Health And Disease ◽  
The Common ◽  
Common Problems

The human uterus consists of the inner endometrium, the myometrium, and the outer serosa. Knowledge of the function of the uterus in health and disease is relevant to reproduction, fertility, embryology, gynaecology, endocrinology, and oncology. Research performed on uterine biopsies is essential to further the current understanding of human uterine biology. This brief review explores the value of the uterine biopsy in gynaecological and human fertility research and explores the common problems encountered when analysing data generated from different types of uterine biopsies, with the aim of improving the quality, reproducibility, and clinical translatability of future research.

scholarly journals Endocrine Disrupting Chemicals: Current Understanding, New Testing Strategies and Future Research Needs

2021 ◽  
Vol 22 (2) ◽  
pp. 933
Author(s):  
Maria E. Street ◽  
Karine Audouze ◽  
Juliette Legler ◽  
Hideko Sone ◽  
Paola Palanza
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Endocrine System ◽  
Current Understanding ◽  
Future Research ◽  
Developmental Origins ◽  
Research Needs ◽  
Important Class ◽  
Testing Strategies ◽  
Endocrine Disrupting ◽  
Health And Disease

Endocrine disrupting chemicals (EDCs) are exogenous chemicals which can disrupt any action of the endocrine system, and are an important class of substances which play a role in the Developmental Origins of Health and Disease (DOHaD) [...]

scholarly journals New diagnostic approach of the different types of isolated craniosynostosis

2020 ◽  
Author(s):  
Sophia A. J. Kronig ◽  
Otto D. M. Kronig ◽  
Henri A. Vrooman ◽  
Jifke F. Veenland ◽  
Léon N. A. Van Adrichem
Keyword(s):  
Diagnostic Approach ◽  
Future Research ◽  
Data Set ◽  
Skull Shape ◽  
Anterior Plagiocephaly ◽  
Different Types ◽  
The Common ◽  
Diagnostic Flowchart ◽  
And Control ◽  
Ct Slices

Abstract In this study, we diagnose skull shape deformities by analysing sinusoid curves obtained from standardized computed tomography (CT) slices of the skull for the common craniosynostoses (scaphocephaly, brachycephaly, trigonocephaly, right- and left-sided anterior plagiocephaly). Scaphocephaly has a high forehead peak and low troughs, in contrast to brachycephaly. Anterior plagiocephaly has asymmetry and shifting of the forehead peak. Trigonocephaly has a high and narrow frontal peak. Control patients have a symmetrical skull shape with low troughs and a high and broader frontal peak. Firstly, we included 5 children of every group of the common craniosynostoses and additionally 5 controls for extraction and calculation of characteristics. A diagnostic flowchart was developed. Secondly, we included a total of 51 craniosynostosis patients to validate the flowchart. All patients were correctly classified using the flowchart. Conclusion: Our study proposes and implements a new diagnostic approach of craniosynostosis. We describe a diagnostic flowchart based on specific characteristics for every type of craniosynostosis related to the specific skull deformities and control patients. All variables are expressed in number; therefore, we are able to use these variables in future research to quantify the different types of craniosynostosis. What is Known:• Premature fusion of one or more cranial sutures results in a specific cranial shape.• Clinical diagnosis is relatively simple; however, objective diagnosis based on distinctive values is difficult. What is New:• Using external landmarks and curve analysis, distinctive variables, and values for every type of craniosynostosis related to the specific skull deformities were determined and used to create a diagnostic flowchart for diagnosis.• Validation with an independent data set of 51 patients showed that all patients were correctly classified.

scholarly journals Current Understanding of the Biomechanics of Ventricular Tissues in Heart Failure

2019 ◽  
Vol 7 (1) ◽  
pp. 2 ◽  
Author(s):  
Wenqiang Liu ◽  
Zhijie Wang
Keyword(s):  
Heart Failure ◽  
Mechanical Properties ◽  
Computational Models ◽  
Ventricular Dysfunction ◽  
Important Determinant ◽  
Current Understanding ◽  
Future Research ◽  
Research Directions ◽  
Future Research Directions ◽  
The Common

Heart failure is the leading cause of death worldwide, and the most common cause of heart failure is ventricular dysfunction. It is well known that the ventricles are anisotropic and viscoelastic tissues and their mechanical properties change in diseased states. The tissue mechanical behavior is an important determinant of the function of ventricles. The aim of this paper is to review the current understanding of the biomechanics of ventricular tissues as well as the clinical significance. We present the common methods of the mechanical measurement of ventricles, the known ventricular mechanical properties including the viscoelasticity of the tissue, the existing computational models, and the clinical relevance of the ventricular mechanical properties. Lastly, we suggest some future research directions to elucidate the roles of the ventricular biomechanics in the ventricular dysfunction to inspire new therapies for heart failure patients.

scholarly journals Mono-6-Substituted Cyclodextrins—Synthesis and Applications

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 5065
Author(s):  
Petr Kasal ◽  
Jindřich Jindřich
Keyword(s):  
Covalent Binding ◽  
Synthetic Methods ◽  
Optimal Solutions ◽  
Glucose Unit ◽  
Intended Purpose ◽  
Wide Range ◽  
Different Types ◽  
The Common ◽  
Common Problems ◽  
Number Of Publications

Cyclodextrins are well known supramolecular hosts used in a wide range of applications. Monosubstitution of native cyclodextrins in the position C-6 of a glucose unit represents the simplest method how to achieve covalent binding of a well-defined host unit into the more complicated systems. These derivatives are relatively easy to prepare; that is why the number of publications describing their preparations exceeds 1400, and the reported synthetic methods are often very similar. Nevertheless, it might be very demanding to decide which of the published methods is the best one for the intended purpose. In the review, we aim to present only the most useful and well-described methods for preparing different types of mono-6-substituted derivatives. We also discuss the common problems encountered during their syntheses and suggest their optimal solutions.

Applying Possessive pronoun in Writing Sentences: Exploring Students’ Ability and Problems in a Mixed Method Study

2019 ◽  
Vol 1 (3) ◽  
pp. 79-83
Author(s):  
Eka Utami Putri ◽  
Syahdan Syahdan
Keyword(s):  
Mixed Method ◽  
Simple Random Sampling ◽  
Average Score ◽  
Mixed Method Study ◽  
Z Score ◽  
Possessive Pronoun ◽  
Efl Students ◽  
The Common ◽  
Common Problems ◽  
Essay Test

The purpose of this research was to find out the students' ability in applying Possessive pronoun in writing sentences and the problems encounter it.  This mixed method study employs an explanatory design to reveals it. 53 students out of 105 students from1st semester EFL students from one reputable University in Pekanbaru, Indonesia, were invited to this study. These 53 students were selected using simple random sampling and enrolled for an essay test and interview to see the students' ability and explaining the problems. The data analysis using SPSS showed that the average score of students was 52.98. Meanwhile for the median is 48, the mode is 20. The score of Standard Deviation is 27.93, Variance is 780.25, and Range is 84.  Z-Score was found 41.5%, which is means higher than average and 58.5% while, students' ability was indicated below the average. It showed that the students were low ability in applying possessive pronoun in writing sentences. The study also found the common problems, i.e., (1) students still mixed up between possessive pronoun and possessive adjectives. (2) students used the wrong pattern in using a possessive pronoun. (3) students did not understand clearly about a possessive pronoun, (4) experiencing difficulties in learning possessive pronoun. 

Overview of Subsynchronous Oscillation in Grid-connected Wind Farm

2020 ◽  
Vol 13 (7) ◽  
pp. 969-979
Author(s):  
Xu Pei-Zhen ◽  
Lu Yong-Geng ◽  
Cao Xi-Min
Keyword(s):  
Power Systems ◽  
Wind Turbine ◽  
Large Scale ◽  
Wind Farm ◽  
Wind Farms ◽  
Induction Generator ◽  
Future Research ◽  
Stable Operation ◽  
Subsynchronous Oscillation ◽  
Different Types

Background: Over the past few years, the subsynchronous oscillation (SSO) caused by the grid-connected wind farm had a bad influence on the stable operation of the system and has now become a bottleneck factor restricting the efficient utilization of wind power. How to mitigate and suppress the phenomenon of SSO of wind farms has become the focus of power system research. Methods: This paper first analyzes the SSO of different types of wind turbines, including squirrelcage induction generator based wind turbine (SCIG-WT), permanent magnet synchronous generator- based wind turbine (PMSG-WT), and doubly-fed induction generator based wind turbine (DFIG-WT). Then, the mechanisms of different types of SSO are proposed with the aim to better understand SSO in large-scale wind integrated power systems, and the main analytical methods suitable for studying the SSO of wind farms are summarized. Results: On the basis of results, using additional damping control suppression methods to solve SSO caused by the flexible power transmission devices and the wind turbine converter is recommended. Conclusion: The current development direction of the SSO of large-scale wind farm grid-connected systems is summarized and the current challenges and recommendations for future research and development are discussed.

Antecedents and Consequences of Gossip in Work Groups

2019 ◽  
pp. 416-434
Author(s):  
Bianca Beersma ◽  
Gerben A. van Kleef ◽  
Maria T. M. Dijkstra
Keyword(s):  
Social Order ◽  
Information Exchange ◽  
Work Groups ◽  
Psychological Theory ◽  
Future Research ◽  
Group Norms ◽  
Group Effectiveness ◽  
Interpersonal Aggression ◽  
Different Types ◽  
Antecedents And Consequences

This chapter provides an overview of the antecedents and consequences of gossip in work groups. First, the chapter reviews the different motives for gossip in work groups (i.e., bonding, entertainment, emotional venting, information exchange, maintenance of group norms/social order, and interpersonal aggression) and links each motive to psychological theory. Second, the chapter reviews the different types of influence that gossip can have on various indicators of group effectiveness. Reflecting on the motives underlying gossip in work groups, as well as on its outcomes, it argues that future research should start integrating the diverse insights provided by earlier research on both gossip motives and outcomes, and it provides a number of suggestions for doing so.

scholarly journals Advantages and potential challenges of data management in e-maintenance

2019 ◽  
Vol 25 (3) ◽  
pp. 378-396 ◽  
Author(s):  
Arian Razmi-Farooji ◽  
Hanna Kropsu-Vehkaperä ◽  
Janne Härkönen ◽  
Harri Haapasalo
Keyword(s):  
Data Management ◽  
Design Methodology ◽  
Management Practices ◽  
Future Research ◽  
Conceptual Approach ◽  
Content Type ◽  
Different Types ◽  
Maintenance Systems ◽  
Industry Leader ◽  
Practical Implications

Purpose The purpose of this paper is twofold: first, to understand data management challenges in e-maintenance systems from a holistically viewpoint through summarizing the earlier scattered research in the field, and second, to present a conceptual approach for addressing these challenges in practice. Design/methodology/approach The study is realized as a combination of a literature review and by the means of analyzing the practices on an industry leader in manufacturing and maintenance services. Findings This research provides a general understanding over data management challenges in e-maintenance and summarizes their associated proposed solutions. In addition, this paper lists and exemplifies different types and sources of data which can be collected in e-maintenance, across different organizational levels. Analyzing the data management practices of an e-maintenance industry leader provides a conceptual approach to address identified challenges in practice. Research limitations/implications Since this paper is based on studying the practices of a single company, it might be limited to generalize the results. Future research topics can focus on each of mentioned data management challenges and also validate the applicability of presented model in other companies and industries. Practical implications Understanding the e-maintenance-related challenges helps maintenance managers and other involved stakeholders in e-maintenance systems to better solve the challenges. Originality/value The so-far literature on e-maintenance has been studied with narrow focus to data and data management in e-maintenance appears as one of the less studied topics in the literature. This research paper contributes to e-maintenance by highlighting the deficiencies of the discussion surrounding the perspectives of data management in e-maintenance by studying all common data management challenges and listing different types of data which need to be acquired in e-maintenance systems.

scholarly journals Advances in Forest Robotics: A State-of-the-Art Survey

Robotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 53
Author(s):  
Luiz F. P. Oliveira ◽  
António P. Moreira ◽  
Manuel F. Silva
Keyword(s):  
Future Research ◽  
Navigation Systems ◽  
Public And Private ◽  
Environmental Preservation ◽  
The Public ◽  
Forest Exploitation ◽  
Different Types ◽  
Scientific Papers ◽  
Great Relevance ◽  
Robotic Applications

The development of robotic systems to operate in forest environments is of great relevance for the public and private sectors. In this sense, this article reviews several scientific papers, research projects and commercial products related to robotic applications for environmental preservation, monitoring, wildfire firefighting, inventory operations, planting, pruning and harvesting. After conducting critical analysis, the main characteristics observed were: (a) the locomotion system is directly affected by the type of environmental monitoring to be performed; (b) different reasons for pruning result in different locomotion and cutting systems; (c) each type of forest, in each season and each type of soil can directly interfere with the navigation technique used; and (d) the integration of the concept of swarm of robots with robots of different types of locomotion systems (land, air or sea) can compensate for the time of executing tasks in unstructured environments. Two major areas are proposed for future research works: Internet of Things (IoT)-based smart forest and navigation systems. It is expected that, with the various characteristics exposed in this paper, the current robotic forest systems will be improved, so that forest exploitation becomes more efficient and sustainable.

scholarly journals Circadian Blood Pressure Rhythm in Cardiovascular and Renal Health and Disease

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 868
Author(s):  
Jiayang Zhang ◽  
Ruoyu Sun ◽  
Tingting Jiang ◽  
Guangrui Yang ◽  
Lihong Chen
Keyword(s):  
Blood Pressure ◽  
Circadian Rhythm ◽  
Molecular Mechanisms ◽  
Current Understanding ◽  
Renal Outcomes ◽  
Circadian Blood Pressure ◽  
Health And Disease ◽  
The Relationship

Blood pressure (BP) follows a circadian rhythm, it increases on waking in the morning and decreases during sleeping at night. Disruption of the circadian BP rhythm has been reported to be associated with worsened cardiovascular and renal outcomes, however the underlying molecular mechanisms are still not clear. In this review, we briefly summarized the current understanding of the circadian BP regulation and provided therapeutic overview of the relationship between circadian BP rhythm and cardiovascular and renal health and disease.

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