scholarly journals Comorbidities and Environmental Factors Associated with Atopic Dermatitis in Children and Adults in Dermatology-Venereology in Cotonou, Benin

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Bérénice Dégboé ◽  
Félix Atadokpèdé ◽  
Christabelle Nguessie ◽  
Alida Kouassi ◽  
Nadège Elégbédé ◽  
...  

Introduction. The objective of this work was to document the comorbidities and environmental factors associated with atopic dermatitis (AD) in dermatology Venereology in Cotonou. Methods. A cross-sectional, prospective, and analytical study included, from January 2016 to December 2018, in the Dermatology-Venereology Department of the National Teaching Hospital Hubert Koutoukou Maga (CNHU-HKM) of Cotonou, children and adults after free and informed consent, in whom the diagnosis of AD was retained according to the criteria of the United Kingdom Working Party. Severity was assessed using SCORAD (severity scoring of atopic dermatitis). Results. The overall prevalence of AD was 7.7%. AD was more frequent in children (56.8% and 40.6%) and adults (59.8% and 37.4%) from urban and periurban areas (0.003 <  p < 0.034 ). It was more frequent in children who regularly dewormed and those with complete vaccination (0.001 <  p < 0.01 ). In 54.8% of children and 58.9% of adults, flare-ups occurred during the warm season. The main associated comorbidities were rhinitis and conjunctivitis in both children (49.7% and 36.1%, respectively) and adults (32.7% and 26.2%, respectively). The main triggering factors in children were heat (43.2%), pneumallergens (28.4%), and skin irritants (22.6%). In adults, we noted skin irritants (58.9%), heat (47.7%), and psychological factors (34.6%). In adults, the use of detergent soaps was associated with lichenified and severe AD (0.003 <  p < 0.006 ) and that of lightening soaps with acute AD ( p = 0.042 ). Conclusion. AD in the Dermatology-Venereology Department of the CNHU-HKM of Cotonou was associated with comorbidities. It was influenced by environmental factors related to the tropical climate and by skin irritants or allergens.

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e042380
Author(s):  
Courtney J Pedersen ◽  
Mohammad J Uddin ◽  
Samir K Saha ◽  
Gary L Darmstadt

ObjectiveDescribe the pattern of atopic disease prevalence from infancy to adulthood.DesignCross-sectional household survey.SettingCommunity-based demographic surveillance site, Mirzapur, Bangladesh.Participants7275 individuals in randomly selected clusters within 156 villages.Primary and secondary outcome measuresThe 12-month prevalence of atopic dermatitis (by UK Working Party Criteria (UK criteria) and International Study of Asthma and Allergies in Childhood (ISAAC)), asthma and rhinitis (by ISAAC); disease severity (by ISAAC); history of ever receiving a medical diagnosis.ResultsChildren aged 2 years had the highest prevalence of atopic dermatitis—18.8% (95% CI 15.2% to 22.4%) by UK criteria and 14.9% (95% CI 11.6% to 18.1%) by ISAAC— and asthma (20.1%, 95% CI 16.4% to 23.8%). Prevalence of rhinitis was highest among 25–29 year olds (6.0%, (95% CI% 4.5 to 7.4%). History of a medical diagnosis was lowest for atopic dermatitis (4.0%) and highest for rhinitis (27.3%) and was significantly associated with severe disease compared with those without severe disease for all three conditions (atopic dermatitis: 30.0% vs 11.7%, p=0.015; asthma; 85.0% vs 60.4%, p<0.001; rhinitis: 34.2% vs 7.3%, p<0.001) and having a higher asset-based wealth score for asthma (29.7% (highest quintile) vs 7.5% (lowest quintile), p<0.001) and rhinitis (39.8% vs 12.5%, p=0.003). Prevalence of having >1 condition was highest (36.2%) at 2 years and decreased with age. Having atopic dermatitis (ISAAC) was associated with significantly increased odds ratios (OR) for comorbid asthma (OR 5.56 (95% CI 4.26 to 7.26)] and rhinitis (3.68 (95% CI 2.73 to 4.96)). Asthma and rhinitis were also strongly associated with each other (OR 8.39 (95% CI 6.48 to 10.86)).ConclusionsAtopic disease burden was high in this rural Bangladeshi population. Having one atopic condition was significantly associated with the presence of another. Low incidence of ever obtaining a medical diagnosis highlights an important opportunity to increase availability of affordable diagnosis and treatment options for all age groups.


2020 ◽  
Vol 48 (2) ◽  
pp. 175-181
Author(s):  
A. Akan ◽  
E. Dibek-Mısırlıoğlu ◽  
E. Civelek ◽  
E. Vezir ◽  
C.N. Kocabaş

2020 ◽  
Vol 34 (8) ◽  
pp. 1764-1772
Author(s):  
J.P. Thyssen ◽  
Y. Andersen ◽  
A.‐S. Halling ◽  
H.C. Williams ◽  
A. Egeberg

Author(s):  
Hai Minh Vu ◽  
Long Hoang Nguyen ◽  
Huong Lan Thi Nguyen ◽  
Giang Thu Vu ◽  
Cuong Tat Nguyen ◽  
...  

Falls and recurrent falls cause great health and social consequences in older people. However, these problems are poorly understood in Vietnam. A cross-sectional study was performed at seven hospitals in Thai Binh province, Vietnam, to investigate the individual and environmental factors associated with recurrent falls among elderly patients hospitalized due to fall injuries in Vietnam. A history of recurrent falls within the last 12 months, sociodemographic, health, and clinical characteristics, as well as environmental conditions, were obtained via self-reported interviews. Multivariate logistic and Poisson regression models were used to identify associated factors. Overall, the mean fall episodes in the last 12 months were 1.8 (Standard deviation—SD = 1.2) episodes, and the 12-month prevalence of recurrent falls was 40.5%. The individual risk factors included not receiving fall prevention guidelines, walking with devices, loss of sensation in hand or foot, and using pain relief medications. The environmental risk factors comprised having too-high stairs and not having dry, clean, and nonslippery bathrooms. This study highlights a significantly high 12-month prevalence of recurrent falls in older patients hospitalized after falls in Vietnam. Moreover, regular assessments of functional disabilities and hazardous environmental conditions, as well as the provision of prevention programs, have potential to prevent falls and recurrent falls.


2021 ◽  
Vol 12 ◽  
Author(s):  
Yi Feng Wen ◽  
Peng Fang ◽  
Jia-xi Peng ◽  
Shengjun Wu ◽  
Xufeng Liu ◽  
...  

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 is challenging the dental community to an unprecedented degree. Knowledge of the increased risk of infection in dental settings has been disseminated to the public and guidelines have been formulated to assist dental attendance decision-making. However, dental attendance behaviors incompatible with treatment need is not uncommon in clinical settings. Important gaps remain in the knowledge about how psychological factors are affecting dental attendance behaviors during the COVID-19 epidemic. In this cross-sectional study, a questionnaire survey was performed during February and March 2020. A total of 342 and 294 dental patients who attended and avoided dental visits, respectively, were included. The participants were classified into four groups based on dental attendance behavior and emergent/urgent dental treatment need. Bivariate analysis was performed to investigate factors associated with dental attendance. Multivariable logistic regression based on principal component scores was performed to identify major psychological constructs associated with unnecessary dental avoidance and attendance. Among all the factors explored, inability to wear masks during dental treatment (P &lt; 0.001; effect size: 0.32) was most closely associated with the overall pattern of dental attendance among participants. Multivariable regression suggested that unnecessary dental avoidance was associated with perceived risk of infection in general and in dental settings (odds ratio [95% CI]: 0.62 [0.53, 0.72]; p &lt; 0.001), perceived impact of COVID-19 and dental problems on general health (0.79 [0.65, 0.97]; 0.021), and personal traits such as trust and anxiety (0.77 [0.61, 0.98]; 0.038). Unnecessary dental attendance was associated with optimism toward the epidemic (1.68 [1.42, 2.01]; &lt;0.001) and trust (1.39 [1.13, 1.74]; 0.002). Multidisciplinary efforts involving dental and medical professionals as well as psychologists are warranted to promote more widespread adoption, among the general public, of dental attendance behaviors compatible with dental treatment need during the COVID-19 epidemic.


2020 ◽  
Vol 14 (8) ◽  
pp. 2737-2745
Author(s):  
Ibrahim Mama Cisse ◽  
Adébayo Alassani ◽  
Mènonli Adjobimey ◽  
Rose Mikponhoue ◽  
Antoine Vikkey Hinsou ◽  
...  

Le paludisme demeure un problème de santé publique au Bénin malgré l’utilisation des moustiquaires. La présente étude avait pour objectif de déterminer la prévalence du paludisme à Tourou et d’identifier les facteurs comportementaux et environnementaux associés en période de faible endémicité. Il s’agissait d’une étude transversale, descriptive à visée analytique menée dans la population de Tourou. Le diagnostic du paludisme était fait par un test de diagnostic rapide. L’analyse des données a été faite par le logiciel SPSS version 21. Les facteurs de risque du paludisme ont été déterminés par régression logistique. Une p inférieure à 0,05 a été considérée comme significative. Au total 390 sujets ont été inclus dans l’étude. Une prédominance féminine (50,6%) est observée avec un sex-ratio de 0,97. Sur les 390 sujets, 145 étaient infectés par le paludisme soit prévalence du 37,4%. Le fait de dormir dehors (OR : 1,31) et après 23 heures (OR : 5,12) étaient des facteurs comportementaux à risque du paludisme tandis que l’absence d’eaux stagnantes (OR : 0,67) et celle des mauvaises herbes (OR : 0,67) étaient les facteurs environnementaux protecteurs contre le paludisme. La présente étude a montré que les facteurs environnementaux et comportementaux sont associés au paludisme dans la localité de Tourou. La lutte contre le paludisme devra considérer en plus de l’éradication du vecteur l’assainissement de l’environnement et le changement du mode de vie.Mots clés : Paludisme, Prévalence, Facteurs associés, Bénin.   English Title: Behavioral and environmental factors associated with malaria in Tourou (Benin) during periods of low endemicityMalaria remains a public health problem in Benin despite the use of mosquito nets. The objective of the present study was to determine the prevalence of malaria in Tourou and to identify behavioral and environmental factors associated to malaria in times of low endemicity. This was a cross-sectional, descriptive, analytical study carried out in the population of Tourou. The diagnosis of malaria was made by a rapid diagnostic test. Data analysis was done by SPSS version 21 software. Factors risk factor with malaria was determined by logistic regression. A p less than 0.05 was considered significant. A total of 390 subjects were included in the study. A female predominance (50.6%) was observed with a sex ratio of 0.97. Of the 390 subjects, 145 were infected with malaria and the prevalence was 37.4%. Sleeping outside (OR: 1.31) and after 11 p.m. (OR: 5.12) were behavioral risk factors for malaria, while the absence of standing water (OR: 0.67) and that of weeds (OR: 0.67) were the protective environmental factors against malaria. The present study has shown that environmental and behavioral factors were associated with malaria in the locality of Tourou. The fight against malaria will have to consider in addition to the eradication of the vector the sanitation of the environment and the change of lifestyle.Keys words: Malaria, prevalence, associated factors, Benin.


2020 ◽  
Author(s):  
Masanja Robert ◽  
Jim Todd ◽  
Bernard J Ngowi ◽  
Sia Msuya ◽  
Angella Ramadhani ◽  
...  

Abstract Background: Tuberculosis (TB) disease is a common opportunistic infection among people living with HIV (PLHIV). WHO recommends at least six months of isoniazid Preventive Therapy (IPT) to reduce the risk of active TB. It is important to monitor completion of IPT, as a suboptimal dose may not protect PLHIV from TB infection. This study determined IPT completion and its determinants among PLHIV aged 15 years or more in Dar es Salaam region, Tanzania. Methods: A Cross-sectional analytical study was conducted using secondary analysis of routine data from 58 care and treatment clinics in Dar es Salaam region. The study recruited clients who screened negative for TB symptoms and initiated IPT between January 2013 and June 2017. Modified Poisson regression model with robust standard errors were used to estimate prevalence ratios (PR) and 95% confidence interval (CI) for factors associated with IPT completion. Multilevel analysis was used to account the health facility random effects in order to estimate independent factors associated with IPT completion. Results : A total of 29,382 clients were initiated on IPT, with 21,808 (74%) female. Overall 17,092 (58%) completed IPT, increasing from 42% (773/1,857) in year 2013 to 76% (2,929/3,856) in 2017. Multilevel multivariable model accounting for health facility as clusters, found that clients with CD4 counts between 100 to 349 cells/ had 3% lower prevalence of IPT completion as compared to those with 100 cells/ (PR:0.97: 95%CI:0.94-1.01). Patients who were not on ART had 46% lower IPT completion compared to those were on ART (PR: 0.54: 95%CI: 0.45-0.64). There was lower IPT completion among clients who transferred to another clinic compared to those attended the same clinic where they were initiated IPT (PR: 0.63: 95% CI (0.54-0.74). Conclusion: IPT completion is low at care and treatment clinics although it increased over time. Lower IPT completion was seen in PLHIV with CD4 counts between 100 to 349 cells/ , those who transferred to other clinics and those not on ART. Thus it indicates the need for better IPT interventions with greater support PLHIV in those groups.


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