scholarly journals Clinical Effect and Aesthetic Observation of All-on-4 Immediate Loading Implant Denture in Severe Periodontitis

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Zhe Cheng ◽  
Wanlai Zheng
Keyword(s):  
Clinical Effect ◽  
Effective Rate ◽  
Good Effect ◽  
Immediate Loading ◽  
Control Group ◽  
Observation Group ◽  
Severe Periodontitis ◽  
Tnf Α ◽  
Periodontal Index ◽  
Significant Difference

Objective. To explore the clinical effect and aesthetics of All-on-4 immediate loading implant denture in severe periodontitis. Methods. Totally, 60 patients with dentition loss caused by severe periodontitis who were admitted to our hospital from February 2017 to February 2019 were selected. The patients were randomly divided into the observation group (n = 30) and the control group (n = 30) according to different restoration methods. The control group was used in traditional implant restoration treatment, and the observation group was used in All-on-4 immediate loading implant denture restoration. The clinical effect, periodontal index, aesthetic effect, and complications of the two groups were compared, and the levels of serum leptin (LEP), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), and interleukin-6 (IL-6) were measured. Results. The total effective rate of the observation group (83.33%) was higher than that of the control group (60.00%) ( P < 0.05 ). After treatment, the plaque index, gingival sulcus bleeding index, and depth of exploration of the two groups were lower than those before treatment ( P < 0.05 ), and there was no significant difference between the two groups ( P > 0.05 ). After treatment, the serum LEP, TNF-α, CRP, and IL-6 in both groups were lower than before treatment, and the serum LEP, TNF-α, CRP, and IL-6 in the observation group were lower than that in the control group ( P < 0.05 ). The aesthetic rate of teeth in the observation group (90.00%) was higher than that in the control group (66.67%) ( P < 0.05 ). There was no significant difference in the total incidence of complications between the two groups ( P > 0.05 ). Conclusion. All-on-4 immediate loading implant denture has a good effect in the treatment of severe periodontitis, which is conducive to maintaining periodontal health, reducing the level of inflammation, improving aesthetics, and has high safety.

scholarly journals Analysis of Clinical Effect of Treating Arrhythmia with Stable Heart Granules

2013 ◽  
Vol 2 ◽  
pp. 7
Author(s):  
Li Liu
Keyword(s):  
Clinical Practice ◽  
Adverse Reactions ◽  
Clinical Effect ◽  
Total Effective Rate ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
The Difference ◽  
And Control ◽  
Group Observation

<p><strong>Objective: </strong>To study the clinical effect on the treatment of cardiac arrhythmia, and further guide the clinical treatment. <strong>Method: </strong>From January 2011 to January 2013, 100 patients with arrhythmia were randomly divided into observation group and control group with 50 cases in each group. Observation group patients given oral Stable heart granule treatment, while control group was treated with oral propafenone treatment. The therapeutic effect and adverse reactions of the two groups were observed and compared. <strong>Results: </strong>The total effective rate of the observation group was higher than control group and incidence of adverse reactions was lower than control group, the difference was statistically significant, <em>p</em> &lt; 0.05. The use of stable heart particles in the treatment of arrhythmia produce significant effect. <strong>Conclusion: </strong>Clinical effect for Stable heart granule on arrhythmia was significant and should widely entrenched in clinical practice.</p>

scholarly journals Treatment of knee osteoarthritis with traditional Chinese medicine sloughingClinical efficacy study

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Liang Wen
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Knee Osteoarthritis ◽  
Western Medicine ◽  
Clinical Effect ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Group A ◽  
Group B

Objective: To explore the clinical effect of the treatment of knee osteoarthritis with traditional Chinese medicine.Methods: 152 patients with knee osteoarthritis who were treated in our hospital from July 2018 to April 2020 were divided into two groups. Group A (control group) was treated with conventional western medicine, i.e. celecoxib 200 mg capsule +Glucosamine hydrochloride capsule 0.75g, group B (observation group): the treatment of traditional Chinese medicine sloughing using our experience formula, and further comparative evaluation of the treatment effect of the two groups. Results: the effective rate was 75% in the control group and 92% in the observation group. Conclusion: in the treatment of knee osteoarthritis, traditional Chinese medicine is more effective than western medicine.

scholarly journals Docetaxel HIPEC Combined with Endostar versus Docetaxel HIPEC Alone in Treatment of Malignant Ascites：A Retrospective Study

2021 ◽  
Author(s):  
Jing Wu ◽  
Hao Jiang ◽  
Liting Chen ◽  
Bingqi Yu ◽  
Zhibing Wu
Keyword(s):  
Qualitative Data ◽  
Adverse Reactions ◽  
Clinical Effect ◽  
Objective Response ◽  
Malignant Ascites ◽  
Control Group ◽  
Observation Group ◽  
Improvement Rate ◽  
Significant Difference

Abstract Objective：The purpose of this study is to retrospectively observe the clinical efficacy and adverse reactions of docetaxel hyperthermic intraperitoneal chemotherapy (HIPEC) combined with endostar in treatment of malignant ascites. Methods：56 cases of malignant ascites admitted to Zhejiang Hospital from July 2019 and October 2020 had received no less than second-line chemotherapy. The observation group (n = 29) was treated with endostar 60mg d1,4,7 Q3W intraperitoneal injection combined with docetaxel 60mg/m2 d4 HIPEC Q3W for 2 cycles. The control group (n = 27) was just treated with docetaxel 60mg/m2 d1 HIPEC Q3W for 2 cycles. The general clinical data and qualitative data of the treatment results were processed by SPSS26.0 using χ2 test, and quantitative data were processed by t test. When P < 0.05, statistical data can be considered statistically significant.Results：There were significant differences between the observation group and the control group in objective response rate (ORR) (65.5% vs 37.0%，P=0.033)，in the improvement rate of KPS (48.3% vs 22.2%, P=0.042)，also in the median control time (57dvs 45d，P=0.027). The incidence of III to IV adverse reactions was low, and no treatment-related death was observed. There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion：Endostar combined with docetaxel HIPEC has good clinical effect on malignant ascites and can improve patients’ quality of life, and the adverse reactions can be tolerated.

scholarly journals The Efficacy of Tripterygium Glycosides Combined with LMWH in Treatment of HSPN in Children

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Yan Jin ◽  
Yanzheng Wang ◽  
Sai Wang ◽  
Qiongqiong Zhao ◽  
Donghua Zhang ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Clinical Symptoms ◽  
Effective Rate ◽  
Control Group ◽  
Clinical Effects ◽  
Observation Group ◽  
Significant Difference ◽  
Before And After ◽  
Qilu Hospital ◽  
Tripterygium Glycosides

Objective. This study aimed to explore the clinical efficacy and relevant mechanism of Tripterygium glycosides combined with low molecular weight heparin calcium (LMWH) in the treatment of Henoch–Schönlein purpura nephritis (HSPN) in children. Methods. 64 cases of children patients with HSPN treated at Qilu Hospital (Qingdao) from January 2015 to May 2020 were selected and randomly divided into the control group and the observation group and 32 cases in each group. Conventional medical treatment was applied in the two groups, besides which the control group was given LMWH while the observation group was given Tripterygium glycosides based on the control group. The clinical efficacy and the indexes of clinical symptoms of the two groups were compared. Immune globulin level, fibrinogen content (FIB), prothrombin time (PT), platelet level (PLT), and activated partial thromboplastin time (APTT) level of the two groups were compared before and after the treatment. Results. The total effective rate in the observation group was significantly higher than that of the control group, and the recurrence rate in the observation group was lower than that in the control group. After treatment, urine red blood cell count and 24 h urine protein were obviously better than those of the control group. There was no statistically significant difference in PT between the two groups of children before and after treatment. The levels of PLT and FIB in the two groups of patients after treatment were significantly lower than before treatment, and the PLT levels in the observation group were lower than those in the control group. Conclusion. The combination of Tripterygium glycosides and LMWH had good clinical effects in the treatment of children with HSPN, and it could improve the clinical symptoms, the mechanism of which might be related to the increase of PT, a decrease of PLT, and the improvement of coagulation function.

scholarly journals Efficacy of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the Management of Malignant Ascites

2020 ◽  
Author(s):  
Jie Jiao ◽  
Chengzhen Li ◽  
Guanying Yu ◽  
Lei Zhang ◽  
Xiaoyan Shi ◽  
...  
Keyword(s):  
Intraperitoneal Chemotherapy ◽  
Adverse Reactions ◽  
Total Effective Rate ◽  
Malignant Ascites ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Short Term ◽  
Significant Difference ◽  
The Difference

Abstract Objective: The purpose of this study is to compare the difference of clinical efficacy between conventional intraperitoneal chemotherapy and HIPEC, so as to explore the clinical application value and advantages of HIPEC.Design: A retrospective analysis was conducted on 80 patients with malignant ascites admitted to our hospital from June 2017 to June 2019. The general clinical data and qualitative data of the treatment results of 80 patients with malignant ascites were processed by SPSS19.0 using χ2 test and quantitative data were processed by t test. P <0.05, statistical data can be considered statistically significant.Results: 1. There was no significant change in vital signs and temperature in the observation group during the treatment, and the difference was not statistically significant 2. The short-term total effective rate of patients in the observation group was 91.11%, and the short-term total effective rate of the patients in the control group was 40%.3. There was no significant difference in the incidence of adverse reactions between the two groups of patients.Conclusion: Intraperitoneal hyperthermic chemotherapy combined with intravenous chemotherapy can significantly control malignant ascites, and has small adverse reactions, which is worthy of clinical promotion and application.

scholarly journals Effect of Buyang Huanwu Decoction Combined with Acupuncture on Sequelae of Cerebral Stroke

2020 ◽  
Vol 185 ◽  
pp. 03018
Author(s):  
Jian Guo ◽  
Deqi Ren ◽  
Xuehui Chang
Keyword(s):  
Barthel Index ◽  
Clinical Effect ◽  
Effective Rate ◽  
Control Group ◽  
Cerebral Stroke ◽  
Clinical Effects ◽  
Buyang Huanwu Decoction ◽  
Nihss Score ◽  
Significant Difference ◽  
Experimental Group

Objective: To explore the clinical effect of the combined use of Buyang Huanwu Decoction and acupuncture in the treatment of patients with sequelae of stroke. Methods: The research work was carried out in our hospital. The study started from September 2018 to September 2019. A total of 100 patients were selected and randomly grouped into experimental group and control group, both groups were given Buyang Huanwu Decoction for intervention, the experimental group were added acupuncture treatment methods on this basis to explore the clinical effects of different intervention methods. Results: There were 4 patients with ineffective treatment in the experimental group, the effective rate was 92.00%, and the effective rate in the control group was 74.00%. The effective rate of the experimental group was higher, and the data was significantly different (P<0.05). After treatment, the FMA, NIHSS score and Barthel index of the patients in the experimental group were (32.66±6.51), (7.11±3.54) and (90.34±9.87) respectively. The FMA score and Barthel index were significantly higher than the control group, and the NIHSS score was lower than the control group, data differences are significant (P<0.05). At the same time, before treatment, there was no significant difference in the scores of TCM syndromes. After treatment, the patients in the experimental group had less hemiplegia, skewed eyes and mouth, eccentric sensation abnormality and consciousness coma scores than that of the control group. The data difference is quite large (P<0.05), the experimental group had better effect. Conclusion: The combined treatment of Buyang Huanwu Decoction and acupuncture in the treatment of patients with sequelae of stroke has a significant clinical effect, which can improve the quality of life of patients, improve the nerve function of patients, and have a positive effect on clinical development.

scholarly journals Clinical effect of Zoledronic Acid in the treatment of Senile Osteoporosis

2020 ◽  
Vol 36 (7) ◽  
Author(s):  
Li Kong ◽  
Kai Zuo ◽  
Long Ma
Keyword(s):  
Bone Mineral Density ◽  
Zoledronic Acid ◽  
Bone Mineral ◽  
Adverse Reactions ◽  
Clinical Effect ◽  
Control Group ◽  
Observation Group ◽  
Mineral Density ◽  
Senile Osteoporosis ◽  
Significant Difference

Objective: To investigate the clinical efficacy of zoledronic acid in the treatment of senile osteoporosis. Methods: One hundred and six cases of senile osteoporosis who visited to our hospital from August 2017 to December 2018 for treatment were selected and randomly divided into a control group and an observation group. The control group was treated with conventional therapy, while the observation group was treated with zoledronic acid in addition to the treatment of the control group. Bone mineral density, pain degree, therapeutic effect and adverse reactions of the two groups were compared. Results: The total effective rate of the observation group was 96.67%, higher than 80.00% of the control group (P<0.05); the bone mineral density of lumbar vertebrae, femoral neck and Ward’ area in the two groups increased after 6 months of treatment, and the bone mineral density of the observation group increased more than that of the control group (P<0.05); the pain degree of the observation group was lower than that of the control group after 6 months of treatment, and the difference was significant (P<0.05). There was no significant difference in the occurrence of adverse reactions between the two groups (P>0.05). Conclusion: Zoledronic acid is helpful to alleviate clinical symptoms, reduce the degree of bone pain, and promote the increase of bone mass, and has high safety in the treatment of senile osteoporosis, which is worth promotion. doi: https://doi.org/10.12669/pjms.36.7.1964 How to cite this:Kong L, Zuo K, Ma L. Clinical effect of Zoledronic Acid in the treatment of Senile Osteoporosis. Pak J Med Sci. 2020;36(7):1703-1707.   doi: https://doi.org/10.12669/pjms.36.7.1964 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Clinical Observation of Self-Made Yin-Tonifying Ophiopogonis Decoction Combined with Rehabilitation New Liquid in the Treatment of Reflux Esophagitis with Deficiency of Stomach Yin

2021 ◽  
Vol 5 (4) ◽  
pp. 112-116
Author(s):  
Liang Wang ◽  
Li Liu ◽  
Zhenghui Liu
Keyword(s):  
Reflux Esophagitis ◽  
Clinical Effect ◽  
Clinical Observation ◽  
Random Number ◽  
Clinical Symptoms ◽  
Total Effective Rate ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Random Number Table

Objective: To observe the efficacy of Yin-tonifying Ophiopogonis Decoction combined with Rehabilitation New Liquid in the treatment of reflux esophagitis (RE). Methods: Seventy-four patients with RE were included in the study and they were divided into an observation group and a control group using the random number table method with 37 cases in each group. The patients in the control group were given oral Yin-tonifying Ophiopogonis Decoction whereas the patients in the observation group were additionally treated with the Rehabilitation New Liquid. The clinical efficacy, traditional Chinese medicine (TCM) symptoms, and the efficiency of gastroscopy were compared between the two groups. Results: The total effective rate of clinical symptoms, TCM symptoms, and gastroscopy results between the observation group and the control group were significantly different (P < 0.05) and were statistically significant. Conclusion: The clinical effect of Yin-tonifying Ophiopogonis Decoction combined with the Rehabilitation New Liquid in the treatment of RE is significant.

Analysis of quality control group of departments on improving effect of PICC maintenance quality in outpatient children with tumor

2021 ◽  
Vol 7 (5) ◽  
pp. 3029-3034
Author(s):  
Qingmei Yi ◽  
Xi Li ◽  
Tingtin Cheng ◽  
Xiaofen Hou ◽  
ZhiGuo Li ◽  
...  
Keyword(s):  
Quality Control ◽  
Clinical Effect ◽  
Service Evaluation ◽  
Control Group ◽  
Observation Group ◽  
Knowledge Level ◽  
Related Risk ◽  
Significant Difference ◽  
Tumor Management ◽  
Outpatient Children

To explore the clinical effect of quality control group of departments on improving PICC maintenance quality in outpatient children with tumor. Methods: A total of 4100 children with tumor who were treated in our outpatient department of intravenous therapy from January to December 2020 were divided into observation group (July to December 2020: after the establishment of quality control department) and control group (January to June 2020: before the establishment of quality control group of departments). In the control group, conventional PICC treatment management and maintenance measures were used. In the observation group, quality control group was used to manage, and moreover, the PICC maintenance quality, the incidence rate of PICC-related risk events and the level of PICC maintenance knowledge and satisfaction evaluation were compared between the two groups. Results: (1) Comparing the PICC maintenance quality between the two groups, the rate of absence of PICC maintenance during the course of tumor management in the observation group (1.14%) was significantly lower than that in the control group (4.00%), and there was significant difference in the PICC maintenance quality between the two groups (P<0.05). (2) Comparing the relative indexes of children with tumor: Before intervention, there was no significant difference in the relative indexes of children with tumor (PICC maintenance knowledge level) between the two groups (P>0.05), but after intervention, the relative indexes of children with tumor (PICC maintenance knowledge level, and service evaluation recognition degree) in the observation group were significantly higher than that in the control group (P<0.05). (3) Comparing the probability of PICC-related risk events between the two groups: In the course of tumor management, PICC-related complications were observed in the observation group (3.59%, 3.18%), which were significantly lower than those in the control group (11.95%, 11.37%) (P<0.05). Conclusion: The application of quality control group of departments in the management of PICC in outpatient children with tumor has obvious clinical effect. It can effectively improve the level of maintenance knowledge and service satisfaction of family members, optimize the quality of maintenance, reduce the rate of lack of maintenance and risk related to PICC, and is worthy of being popularized in clinical practice.

scholarly journals Effects of Misoprostol and Oxytocin Combined with Calcium Gluconate on Delivery Time of Parturient with High-risk Postpartum Hemorrhage and Neonatal Outcomes

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Rongfang Chen ◽  
Wenwen Shuo
Keyword(s):  
High Risk ◽  
Calcium Gluconate ◽  
Apgar Score ◽  
Postpartum Hemorrhage ◽  
Effective Rate ◽  
Control Group ◽  
Observation Group ◽  
Delivery Time ◽  
Significant Difference ◽  
The Difference

Objective: To investigate the effect of misoprostol and oxytocin combined with calcium gluconate on parturient with high-risk postpartum hemorrhage. Methods: The clinical data of 80 parturient with high-risk postpartum hemorrhage who were treated in our hospital from July 2016 to July 2019 were retrospectively analyzed. According to different treatment methods, they were divided into control group (treated with misoprostol combined with oxytocin, 40 cases) and observation group (treated with misoprostol and oxytocin combined with calcium gluconate, 40 cases), compared the clinical efficacy, delivery time, postpartum hemorrhage 2 hour after delivery, postpartum hemorrhage 24 hours after delivery and Apgar score of the newborns at 1min after birth. Results: The total effective rate (95.00%) in the observation group was higher than that in the control group (77.50%), and the difference was statistically significant (P<0.05). The third delivery stage in the observation group was shorter than that in the control group, and the postpartum hemorrhage volume was less than that in the control group. The difference was statistically significant (P<0.05). There was no significant difference in Apgar score of the two groups of newborns (P>0.05). Conclusion: Misoprostol and oxytocin combined with calcium gluconate is effective in treating high-risk postpartum hemorrhage parturient, which not only can effectively reduce postpartum hemorrhage and shorten the delivery time, but also is beneficial for neonatal outcome and worthy of clinical application.

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