scholarly journals Backpropagation Neural Network Algorithm-Based Color Doppler Ultrasound Detection of Gestational Diabetes Mellitus and Perinatal Outcomes

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Xiaoqing Zhang ◽  
Yinsu Lou ◽  
Sunhao Hu ◽  
Dan Zhu
Keyword(s):  
Diabetes Mellitus ◽  
Pregnant Women ◽  
Color Doppler ◽  
Perinatal Outcomes ◽  
Color Doppler Ultrasound ◽  
Related Risk ◽  
History Of ◽  
Group A ◽  
Family History Of Hypertension ◽  
Group B

In this work, the related risk factors and perinatal outcomes of pregnant women with gestational diabetes mellitus (GDM) were analyzed based on color Doppler ultrasound (CDU) diagnosis. Backpropagation (BP) algorithm-based CDU imaging algorithm (BPC) was constructed in this study and applied in CDU images of 80 pregnant women with GDM. Besides, amplitude and phase estimation (APES) and low-complexity adaptive beam (LCA) algorithms were introduced for comparison with BPC in turn. It was found that Dice similarity coefficient (96.44%), sensitivity (95.45%), and specificity (91.56%) of BPC were greater than those of APES (83.97%, 85.84%, 78.45%) and LCA (84.74%, 86.29%, 82.35%), while its running time (6.44 ± 1.39 s) was shorter than that of APES (11.87 ± 2.41 s) and LCA (13.76 ± 1.54 s) ( P < 0.05 ). Pregnant women in the experimental group (group B) were older than those in the control group (group A) ( P < 0.05 ). The pulsatility index (PI) and renal artery resistance index (RI) of fetuses in group B (0.95 ± 0.15) were higher than those of group A (0.57 ± 0.24) ( P < 0.05 ). In addition, pregnancy age, family history of hypertension, and abortion history were positively correlated with GDM ( P < 0.05 ). In conclusion, BPC could not only improve diagnosis accuracy in fetuses’ CDU images but also shorten calculation time. Pregnancy age, family history of hypertension, and abortion history were the related risk factors for GDM in pregnant women.

Diabetes mellitus: An adverse prognosis in cancer patients—Study of a cohort treated at Instituto Oncológico Henry Moore (IOHM).

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e18212-e18212
Author(s):  
Ernesto Gil Deza ◽  
Julio Cesar Bragagnolo ◽  
Eduardo L. Morgenfeld ◽  
Marta Dragosky ◽  
Natasha Gercovich ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cox Regression ◽  
Diabetic Patients ◽  
Cancer Evolution ◽  
Oncological Treatment ◽  
Oral Hypoglycemics ◽  
History Of ◽  
Group A ◽  
Group B ◽  
Adverse Factor

e18212 Background: Numerous studies have evaluated the unfavorable impact of diabetes mellitus (DM) on cancer evolution. The objective of this paper is to study the coexistence of DM and cancer diagnosis; and its influence on the evolution of a cohort followed at IOHM. Methods: Between 9/26/2012 and 11/28/2018 all new patients (Pt) admitted to IOHM filled out a Past Medical History Form (PMHF) (ASCO 2013 ABST. e17539) with their preexisting clinical conditions.The database was locked and anonymized. Those with a history of DM or who were taking insulin and/ or oral antidiabetics were selected (Group A). The stage and evolution of their tumors were compared with those of non-diabetic patients (Group B). Results: Out of 15,617 Pt, 1,829 Pt (11,7%) had DM (Group A); 1,087 Pt were being treated with oral hypoglycemics (59%); 178 Pt with insulin (10%) and 564 Pt (31%) were not on antidiabetics drugs. They were compared to 13,788 Pt without DM (Group B). Oncological treatment was similar in both groups. Mortality was greaterin DM Patients adjusted by sex, age, PS, BMI, Dx and stage; Multivariate Cox Regression (p = 0.0001). The results are presented in the chart below. Conclusions: 1) In a cohort of 15,617 cancer Pt, 11,7% had DM. 2) DM Pt's tumors were more advanced. 3) Under similar treatments, DM Pt presented higher mortality. 4) Based on this, we advocate for DM in oncological Pt to be considered as an independent adverse factor.[Table: see text]

scholarly journals Evaluation of complements serum level (C3 and C4) in pregnant women with history of toxoplasmosis

2011 ◽  
Vol 5 (2) ◽  
pp. 12-16
Author(s):  
Dunya F. Salloom ◽  
Harith S. AL-Warid ◽  
Ali H. Abbas
Keyword(s):  
Immune Response ◽  
Serum Level ◽  
Pregnant Women ◽  
Normal Pregnancy ◽  
Igm Antibodies ◽  
History Of ◽  
Group A ◽  
Group B ◽  
Group D

C3 and C4 serum level were evaluated in 30 pregnant women which divided into groups: Group A16 (53.3%) (Pregnant women with history of abortion and positive anti toxoplasma IgM antibodies), Group B10 (33%) (Normal pregnancy women with no history of abortion or Toxoplasmosis.), Group C6 (20%) (Pregnant women with history of two abortion and positive anti toxoplasma IgM), group D 10 (33.3%) (Pregnant women with history of only one abortion and positive anti- toxoplasma IgM), group E 4 (13.3%) (Pregnant women with history of only one abortion and negative anti-toxoplasma IgM). The results showed that highest level of both C3 and C4 in women with positive anti toxplasma IgM and history of one or two abortion/abortions while the lowest level of these two complements were in women with negative anti toxplasma IgM even they had one abortion or no abortion. There is significant differences in concentration of C3 ( 189.7 ± 20.3 mg/dl ) and C4 ( 59.3 ± 7.5 mg/dl ) in group A and C3 ( 189.6 ± 17.7 mg/dl ) and C4 ( 63.08 ± 4.7 mg/dl) when compared with group B and E, and the result showed statistical differences in C4 concentration between group C and D at P< 0.05. We conclude that complement was play role in immune response of pregnant women especially against toxoplasmosis that cause abortion to these women.

scholarly journals An Effective and Simple Way to Establish Elastase-Induced Middle Carotid Artery Fusiform Aneurysms in Rabbits

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Yanxia Lyu ◽  
Jie Luo ◽  
Yonghong Zhang ◽  
ChaoJia Wang ◽  
AnRong Li ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Carotid Artery ◽  
Color Doppler ◽  
Cerebral Aneurysms ◽  
Basic Research ◽  
Color Doppler Ultrasound ◽  
Middle Part ◽  
Medication Group ◽  
Group A ◽  
Group B

Objective. Elastase-induced aneurysms in rabbits have been proposed as a preclinical tool for device development, but there is still much deficiency in those aneurismal models. So we need to explore the efficient and convenient animal models for the investigation of intracranial aneurysms. Then, we compared and analyzed three methods of elastase-induced carotid artery aneurysms in rabbits and aimed to find a simple, effective, and reproducible method for creating elastase-induced aneurysms. Methods. 42 standard feeding male adult Japanese white rabbits (3.05±0.65 kg) were randomly divided into 3 groups and treated with elastase ablation to create common carotid artery (RCCA) aneurysm models: Group A (root-RCCA medication group, n=12), Group B (mid-RCCA medication group, n=18), and Group C (ligated RCCA+medication group, n=12). For Group A, the origin of the RCCA was blocked by two temporary aneurysm clips, and the resulting 2 cm cavity was infused with elastase for 20 min, then the clip was removed and the RCCA was not ligated. For Group B, the middle part of RCCA was treated the same way as Group A and the RCCA was not ligated. For Group C, the middle part of RCCA was treated as Group B, but the distal RCCA was ligated. After the aneurysm models were created for 3 weeks, prior to sacrificing the animals, color Doppler ultrasound and angiography were performed for blood flow measurements inside the aneurysms. Histological analysis (such as SMA-α, CD31, CD34, CD68, collagen IV, and Ki67) and the other relevant indexes were compared between the ideal model’s aneurysmal tissues and the human intracranial aneurysm’s tissues to confirm whether we have successfully established elastase-induced aneurysm models. Results. Compared with human intracranial aneurysm specimens by the color Doppler ultrasound, angiography, and changes in the inner diameter of arteries, all three methods have successfully established the elastase-induced aneurysm models. Histology showed that biological responses were similar to both human cerebral aneurysms and previously published elastase-induced rabbit aneurysm models. Group A and Group B had the same morphology, but Group A had a higher mortality rate than Group B. Group B and Group C had different morphology. The aneurysm of Group C was more similar to human cerebral aneurysms but had a higher mortality rate than Group B. Group B was confirmed not only as an alternative method but also as a more safe and effective method for creating elastase-induced aneurysm models. Conclusion. Through analysis and comparison, the Group B is proven to be the simplest, reproducible, and most effective modeling method. The aneurysm model established by Group B can be used for basic research related to aneurysm mechanism. We have provided a new and effective method for basic research on aneurysm.

scholarly journals Intelligent Algorithm-Based Analysis on Ultrasound Image Characteristics of Patients with Lower Extremity Arteriosclerosis Occlusion and Its Correlation with Diabetic Mellitus Foot

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
YunShuang Wu ◽  
Yan Shen ◽  
Hailing Sun
Keyword(s):  
Lower Extremity ◽  
Doppler Ultrasound ◽  
Femoral Artery ◽  
Color Doppler ◽  
Color Doppler Ultrasound ◽  
Ultrasound Images ◽  
Diabetic Mellitus ◽  
Intelligent Algorithm ◽  
Group A ◽  
Group B

Objective. The study focused on the correlation between lower extremity arteriosclerosis and diabetic mellitus (DM) foot, and it was explored by virtue of ultrasound images processed by an intelligent algorithm. Methods. A total of 60 DM foot patients admitted to our hospital in the past three years were selected and divided into two groups according to their condition. Patients with DM foot alone were in group B (30 cases), and patients with DM foot combined with lower extremity arteriosclerosis occlusion were in group C (30 cases). 30 healthy people were in group A as a control. Color Doppler ultrasound was used to examine the arteries of the lower extremities of all subjects. It the intramedia thickness (IMT) from the femoral artery to the dorsal foot artery was recorded, whether there was plaque in the artery or knowing the size of the plaque, its echo, and distribution, and whether the artery had stenosis. Next, the stenosis percentage was calculated. Additionally, the general information of patients was analyzed. At the same time, an intelligent algorithm was used to process ultrasound images, and its effects on image quality were evaluated. Results. Doppler ultrasound images processed by Artificial Bee Colony (ABC) had less noise and better quality, and key information about the lesion was clearly displayed. There was no statistical difference between the general data of the three groups of patients; group B and group C had higher IMT value, plaque incidence, arterial stenosis incidence, and degree of stenosis versus group A, and there were statistically significant differences between groups B and C. In particular, the incidence of femoral artery stenosis and the degree of stenosis were significantly higher in group C than in group B. The rate of stenosis above grade I in group C was as high as 71%, while that in group B was only 19%; in Group C, the incidence of stenosis above grade II was 30%, and that in group B was 13.1%. Compared with group A, group B and group C had decreased peak arterial blood velocity (PSV), resistance index (RI), and pulse index (PI), and there were statistically significant differences between groups B and C. Conclusion. DM foot is a risk factor for arteriosclerosis occlusion; color Doppler ultrasound demonstrates good diagnostic effects on arteriosclerosis occlusion; the algorithm proposed in this study can improve the quality of Doppler ultrasound images and has a high application value.

scholarly journals Gestational diabetes mellitus: does treatment modality predict the obstetric and neonatal outcome?

2017 ◽  
Vol 7 (1) ◽  
pp. 262
Author(s):  
Lopamudra B. John ◽  
Reddi Rani P. ◽  
Seetesh Ghose
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Neonatal Outcome ◽  
Previous History ◽  
Treatment Modalities ◽  
History Of ◽  
Group A ◽  
Group B ◽  
The Impact

Background: Gestational diabetes mellitus (GDM) may be controlled with dietary modifications alone or may require insulin treatment. This study aims to find out the impact of these two treatment modalities on the maternal and neonatal outcomes.Methods: This retrospective observational study divided the GDM patients into two groups, A and B, treated with diet and insulin therapy respectively and the maternal and neonatal outcome parameters were compared.Results: 299 (6.7%) GDM patients over a period of two years were divided into group A (n=222) and group B (n=77). Need for induction of labour was significantly higher in group B (p=0.02). More number of history of previous abortions were seen in group A (p=0.1) and higher number of emergency Caesarean sections were observed in group B (p=0.1). Previous history of intrauterine deaths, gestational hypertension and hypothyroidism in the present pregnancy, meconium stained liquor, large for gestational age babies and need for neonatal intensive care were comparable in the two groups.Conclusions: There are no significant differences in the pregnancy outcomes of GDM treated with diet therapy alone or insulin except for a higher number of induced labours in the insulin treated group.

Analysis of Perinatal Outcome of Normal Pregnant Women with Diabetes Mellitus

2021 ◽  
Vol 7 (5) ◽  
pp. 1378-1382
Author(s):  
Sitong Lin ◽  
Yushan Guo
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Pregnant Women ◽  
Perinatal Outcome ◽  
Adverse Pregnancy Outcome ◽  
Perinatal Complications ◽  
Group A ◽  
Group B

The perinatal outcome of normal pregnant women with gestational diabetes mellitus was analyzed. Methods: The subjects were 50 pregnant women admitted to our hospital from September 2018 to 2019. According to the control of blood glucose level, they were divided into two groups: group A and group B. 32 pregnant women in group A had ideal control of blood glucose and 18 in group B had unsatisfactory control of blood glucose. The adverse pregnancy outcome, comparison of blood lipid and lipoprotein, quality of life score, perinatal complications and other relevant conditions were observed. Result: The adverse pregnancy outcome of group A was significantly lower than that of group B (P < 0.05); the lipid and lipid protein of group A was significantly better than that of group B (P < 0.05); the quality-of-life score of group A was significantly better than that of group B (P < 0.05); the perinatal complications of group A was significantly lower than that of group B (P < 0.05). Conclusion: The control of blood bottle level of pregnant women with gestational diabetes mellitus is beneficial to the perinatal outcome, reduce the incidence of complications of pregnant women and newborns, and significantly improve the quality of life of pregnant women.

scholarly journals A study in Bundelkhand region of Madhya Pradesh, India to assess the risk factors and correlates of pre-eclamptic toxemia

2017 ◽  
Vol 6 (4) ◽  
pp. 1249
Author(s):  
Shikha Pandey ◽  
Ramesh Pandey
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Body Mass Index ◽  
Pregnant Women ◽  
Twin Pregnancy ◽  
Madhya Pradesh ◽  
College Hospital ◽  
Medical College ◽  
History Of ◽  
Family History Of Hypertension

Background: Pre-eclamptic toxemia is pregnancy-induced hypertension (PIH) manifesting in second trimester and affecting multiple systems. The objective was to study the factors of pre-eclampsia in pregnant women admitted for delivery in Bundelkhand Medical college hospital Sagar, Madhya Pradesh, India.Methods: A case-control study was conducted at Bundelkhand Medical College Hospital in Sagar, Madhya Pradesh, India. Criteria in selection of pregnant women with pre-eclampsia comprised those who had hypertension after the 20th week of gestation with associated proteinuria, and controls were pregnant women who were not diagnosed with pre-eclampsia. Total of 100 cases and 100 controls were selected for the year 2015. Factors in study included mother's age, parity, body mass index, history of chronic hypertension, history of diabetes, history of renal disease, family history of hypertension, and history of pre-eclampsia in earlier pregnancy. Crude and adjusted odds ratio with 95% CI and Chi-square test were used for statistical analysis.Results: Major risk factors identified in univariate analysis included before pregnancy body mass index (BMI >25) (OR=11.27), history of hypertension (OR=8.65), history of diabetes mellitus (OR=11.0), history of renal disorders (OR=7.98), familial history of hypertension (OR=5.4), history of PIH in earlier pregnancy (OR=9.63), and twin pregnancy (OR=4.85). As per multiple logistic regression analysis the pre-pregnancy BMI of >25 (OR=7.56), history of hypertension (OR=6.69), history of diabetes mellitus (OR=8.66), history of renal disease (OR=5.6), family history of hypertension (OR=5.48), and twin pregnancy (OR=5.73) are the significant risk factors of pre-eclampsia.Conclusions: The pregnant women at risk of pre-eclampsia should be identified early and high-quality antenatal care should be provided in order to minimize the complications of pre-eclampsia both for the mother and the fetus. 

scholarly journals Glycemic Status and In-hospital Complications in Acute Ischemic Stroke

2018 ◽  
Vol 8 (2) ◽  
pp. 44-48
Author(s):  
Md Amir Hossain ◽  
MA Hannan ◽  
Ripon Barua ◽  
Mohammed Shahadat Hossain ◽  
Sharif Uddin Ahmed ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Urinary Tract Infection ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Electrolyte Imbalance ◽  
Glycemic Status ◽  
History Of ◽  
Group A ◽  
Group B ◽  
The Impact

Although on-admission high glycemic status in acute ischemic stroke (AIS) patients is associated with poor in-hospital outcome, the impact of on-admission different glycemic status in AIS is less clear. This prognostic cohort study was aimed to evaluate the association of on-admission high glycemic status with in-hospital complications of AIS patients. This study was conducted by measurement of random blood glucose (RBG) in 90 AIS patients within 24 hours of hospitalization. The patients were divided into three groups based on their RBG in mg/dl: Group A <120, Group B 120-180 and Group C >180. The average age was 59 years and 35.6% patients were diabetic. In AIS patients, higher RBG was associated with increased in-hospital complications regardless of a history of diabetes mellitus (p=0.047, 0.040, 0.003 and 0.015 for urinary tract infection, bed sore, electrolyte imbalance and mixed complications respectively). Optimal glucose targets in hospitalized patients with AIS are currently undetermined. Glycemic and nonglycemic interventions should be studied for their impact on in-hospital complications and cost.J Shaheed Suhrawardy Med Coll, December 2016, Vol.8(2); 44-48

Appreciation of the importance of pregravid preparation and reproductive attitudes of women of childbearing age in the city of Omsk

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 48-52
Author(s):  
E N Kravchenko ◽  
R A Morgunov
Keyword(s):  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Pregnancy And Childbirth ◽  
Perinatal Center ◽  
History Of ◽  
Group A ◽  
Group B ◽  
Complicated Pregnancy ◽  
The Relationship ◽  
The City

The aim of the study. Assess the importance of pregravid preparation and outcomes of pregnancy and childbirth, depending on the reproductive attitudes of women in the city of Omsk. Materials and methods. The study included 92 women who were divided into groups: group A (n=43) - women whose pregnancy was planned; group B (n=49) - women whose pregnancy occurred accidentally. Each group was divided into subgroups depending on age: from 18 to 30 and from 31 to 49 years. For each patient included in the study, a specially designed map was filled out. These patients were interviewed at the City Clinical Perinatal Center. Results. Comparative analysis revealed the relationship between the reproductive settings of women of childbearing age and the peculiarity of the course of pregnancy and childbirth in these patients. Summary. The majority of women of fertile age are married: in subgroup AA - 25 (96.2%), AB - 13 (76.5%), BA - 25 (92.6%), BB - 20 (91.0%). The predominant number of women of fertile age have one or more abortions: in subgroup AA - 12 (46.2%), AB - 6 (35.3%), in subgroups of comparison BA - 8 (29.6%), BB - 6 (27.3%). More than half of the women of fertile age surveyed have a history of untreated cervical pathology (from 40.8% to 64.7%). The course of pregnancy in women planning pregnancy in most cases proceeded without complications: in subgroup AA - 13 (50.0%), AB - 11 (64.7%). The most common cause of complicated pregnancy in women whose pregnancy occurred accidentally is the threat of spontaneous miscarriage: in subgroup BA - 15 (55.6%), BB - 16 (72.7%). The uncomplicated course of labor more often [subgroup AA - 19 (73.0%), AB - 12 (70.6%)] was observed in women whose pregnancy was planned and they were motivated to give birth to a healthy child.

scholarly journals myo-Inositol Supplementation and Onset of Gestational Diabetes Mellitus in Pregnant Women With a Family History of Type 2 Diabetes: A prospective, randomized, placebo-controlled study

Diabetes Care ◽  
2013 ◽  
Vol 36 (4) ◽  
pp. 854-857 ◽  
Author(s):  
R. D'Anna ◽  
A. Scilipoti ◽  
D. Giordano ◽  
C. Caruso ◽  
M. L. Cannata ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Family History ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Controlled Study ◽  
History Of
Sign in / Sign up

Export Citation Format

Share Document