scholarly journals Human Papilloma Virus: Current Knowledge and Focus on Oral Health

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Luca Fiorillo ◽  
Gabriele Cervino ◽  
Giovanni Surace ◽  
Rosa De Stefano ◽  
Luigi Laino ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Human Papilloma Virus ◽  
Current Knowledge ◽  
Therapeutic Strategies ◽  
Papilloma Virus ◽  
Scientific Databases ◽  
Different Types ◽  
Oral Hpv ◽  
Type Of Injury

The human papilloma virus (HPV) is responsible for different pathological manifestations in humans. This agent gives rise to lesions of different types and in different areas of the organism, including the oral cavity. The aim of this study is to show which are the main diseases for which HPV is responsible and to bring to light some of the interceptive and therapeutic strategies. The analysis was conducted by consulting the major scientific databases with the aim of obtaining information on the characteristics of oral HPV and its management; furthermore, the literature was supported by some clinical cases proposed by the authors. The role of dentistry is essential in the early diagnosis of this type of pathologies and above all in knowing how to direct patients towards a path that can lead to patient management, especially in the event that these lesions have a malignant potential. Enhancing the knowledge and role of dentistry can lead to early diagnosis of this type of injury, intercepting a pathology that could have multiorgan implications.

A Synopsis on the Role of Human Papilloma Virus Infection in Cervical Cancer

2018 ◽  
Vol 19 (9) ◽  
pp. 798-805 ◽  
Author(s):  
Mohd Saeed ◽  
Fawaz D. Alshammari ◽  
Md. Jahoor Alam ◽  
Khan Mohd Sarim ◽  
Khurshid Ahmad ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Virus Infection ◽  
Human Papilloma Virus ◽  
Human Papilloma Virus Infection ◽  
Papilloma Virus

scholarly journals Prostate cancer and the human papilloma virus: causative association, role of vaccines, and the impact of the COVID-19 pandemic

2021 ◽  
Author(s):  
Naomi Morka ◽  
Joseph M. Norris ◽  
Mark Emberton ◽  
Daniel Kelly
Keyword(s):  
Prostate Cancer ◽  
Human Papilloma Virus ◽  
Hpv Vaccination ◽  
Significant Proportion ◽  
Vaccine Uptake ◽  
Papilloma Virus ◽  
Vaccination Campaigns ◽  
The Impact ◽  
Hpv Vaccine Uptake

AbstractProstate cancer affects a significant proportion of men worldwide. Evidence from genetic and clinical studies suggests that there may be a causal association between prostate cancer and the human papilloma virus (HPV). As HPV is a vaccine-preventable pathogen, the possibility of a role in prostate cancer causation may reinforce the importance of effective HPV vaccination campaigns. This is of particular relevance in light of the COVID-19 pandemic, which may have considerable effects on HPV vaccine uptake and distribution.

scholarly journals HUBUNGAN PENGETAHUAN, STATUS EKONOMI, PERAN PETUGAS KESEHATAN DAN PERAN KELUARGA TERHADAP VAKSINASI HPV (HUMAN PAPILLOMA VIRUS) DI KLINIK DARA JINGGA KOTA JAMBI TAHUN 2017

2018 ◽  
Vol 18 (1) ◽  
pp. 215
Author(s):  
Nia Nurzia
Keyword(s):  
Human Papilloma Virus ◽  
Health Personnel ◽  
Economic Status ◽  
Hpv Vaccination ◽  
P Value ◽  
Papilloma Virus ◽  
The Family ◽  
The Relationship ◽  
Hpv Human Papilloma Virus

Abnormal cervical is still  in high levels of  which marked by the outbreak of the Human Papilloma Virus, It is not offset by the use of vaccination (HPV) Human Papilloma Virus which as the primary prevention of the spread of Human Papilloma Virus . recorded in Dara Jingga clinic in  2015, there were 226 people in the state of the cervix abnormal while those who making vaccination extremely low at only 40 people. Likewise, in 2016 there were 301 people in a state of abnormal cervical and vaccinated only 16 people . Based on it, this research is the research which aimed to determine the relationship between knowledge, economic status, family role and the role of health personnel  against the Human Papilloma Virus vaccination in Dara Jingga Clinic  Jambi City. This research is descriptive analytic with cross sectional design, the data collected through questionnaires, with a population was 321 people. using  acidental sampling technique with  sample was 32 people, research has been conducted on 22 to 24 August 2016 using univariate  and bivariate analysis assisted by a computer program. The results of the univariate analysis of vaccination picture were 10 respondents (31.3%) take advantage of HPV vaccination and 22 respondents (68,8%) did not take advantage of the HPV vaccination, an overview of knowledge were five respondents (15,6%) have sufficient knowledge, 15 respondents (46,9%) had a good knowledge,12 respondents (37,5%) had poor knowledge, an overview of economic status,  13 respondents (40,6%) had high economic status and  19 respondents (59,4% ) have lower economic status, description of the role of health workers13 respondents (40,6%) have a good role of health personnel and  19 respondents (59,4%) has the role of health personnel is not good. Overview of the role of the family, 11 respondents (34,4%) has the role of a good family and  21 respondents (65,6%) had a family roles goodles. the result of these studies show a relationship between the mother's knowledge by vaccination with HPV (Human Papilloma Virus ) with a p value of 0,035, the relationship between economic status with vaccination HPV (Human Papilloma Virus with p value 0,002, their relationship with the role of HPV vaccination of health workers with p value 0,002, their relationship with the family role of HPV vaccination with a p value of 0,004.Keywords: Knowledge, Economic Status, Role of health personnel, Role of Family,HPV Vaccination (Human Papilloma Virus)

scholarly journals Mitochondrial Mechanisms of Apoptosis and Necroptosis in Liver Diseases

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Qingfei Chu ◽  
Xinyu Gu ◽  
Qiuxian Zheng ◽  
Jing Wang ◽  
Haihong Zhu
Keyword(s):  
Cell Death ◽  
Liver Cirrhosis ◽  
Liver Disease ◽  
Programmed Cell Death ◽  
Liver Diseases ◽  
Current Knowledge ◽  
Therapeutic Strategies ◽  
Cellular Energetics ◽  
Liver Cell Death

In addition to playing a pivotal role in cellular energetics and biosynthesis, mitochondrial components are key operators in the regulation of cell death. In addition to apoptosis, necrosis is a highly relevant form of programmed liver cell death. Differential activation of specific forms of programmed cell death may not only affect the outcome of liver disease but may also provide new opportunities for therapeutic intervention. This review describes the role of mitochondria in cell death and the mechanism that leads to chronic liver hepatitis and liver cirrhosis. We focus on mitochondrial-driven apoptosis and current knowledge of necroptosis and discuss therapeutic strategies for targeting mitochondrial-mediated cell death in liver diseases.

scholarly journals Multifaceted role of tensins in cancer

2019 ◽  
Author(s):  
Abdulaziz Alfahed ◽  
Teresa P Raposo ◽  
Mohammad Ilyas
Keyword(s):  
Cancer Biology ◽  
Focal Adhesions ◽  
Adaptor Proteins ◽  
Therapeutic Strategies ◽  
Cell Behavior ◽  
Surrounding Environment ◽  
Signaling Mechanisms ◽  
Different Types ◽  
Biochemical Signals

Tensins are structural adaptor proteins localized at focal adhesions. Tensins can act as mechanosensors and participate in the transduction of biochemical signals from the extracellular matrix to the cytoskeleton, acting as an interface able to alter cell behavior in responses to changes in their surrounding environment. This review aims to provide a concise summary of the main functions of the four known tensins in cell and cancer biology, their homology and recently unveiled signaling mechanisms. We focus specifically on how tensin 4 (TNS4/Cten) may contribute to cancer both as an oncogene supporting metastasis and as tumour suppressor in different types of tissue. A better understanding of the cancer mechanistics involving tensins may provide the rationale for development of specific therapeutic strategies.

scholarly journals The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas

2013 ◽  
Vol 2013 ◽  
pp. 1-15 ◽  
Author(s):  
Helen Könnecke ◽  
Ingo Bechmann
Keyword(s):  
Multiple Sclerosis ◽  
Matrix Metalloproteinases ◽  
Current Knowledge ◽  
Malignant Gliomas ◽  
Therapeutic Strategies ◽  
Glioma Invasion ◽  
Glia Limitans ◽  
And Migration

Matrix metalloproteinases (MMPs) are involved in the pathogenesis of neuroinflammatory diseases (such as multiple sclerosis) as well as in the expansion of malignant gliomas because they facilitate penetration of anatomical barriers (such as the glia limitans) and migration within the neuropil. This review elucidates pathomechanisms and summarizes the current knowledge of the involvement of MMPs in neuroinflammation and glioma, invasion highlighting microglia as major sources of MMPs. The induction of expression, suppression, and multiple pathways of function of MMPs in these scenarios will also be discussed. Understanding the induction and action of MMPs might provide valuable information and reveal attractive targets for future therapeutic strategies.

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