scholarly journals Arsenic Content, Speciation, and Distribution in Wild Cordyceps sinensis

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Yuancan Xiao ◽  
Cen Li ◽  
Wei Xu ◽  
Yuzhi Du ◽  
Ming Zhang ◽  
...  
Keyword(s):  
Quality Control ◽  
Imaging Techniques ◽  
Arsenic Speciation ◽  
Chemical Form ◽  
Cordyceps Sinensis ◽  
Arsenic Content ◽  
Chemical Forms ◽  
Total Arsenic ◽  
Icp Ms ◽  
Source Studies

The excessive arsenic content in wild Cordyceps sinensis has caused great concerns on human health. The toxicity of arsenic depends on its concentration, chemical form, and valence. The source studies of arsenic in C. sinensis are essential for safety evolution and quality control. We used ICP-MS and HPLC-ICP-MS methods to determine the total arsenic amount and the arsenic speciation. Synchrotron-based XANES and micro-XRF imaging techniques were used to characterize arsenic valence and distribution. The total arsenic amount range in wild C. sinensis samples was 5.77–13.20 μg/g with an average of 8.85 ± 2.5 μg/g. As(III) and As(V) were the main species in wild C. sinensis samples. The iAs only accounts for 4.47–11.42% of the extracted arsenic. Trivalent and pentavalent forms were the dominant chemical forms of arsenic. Besides, we found that arsenic was accumulated at the digestive tract of the host larva.

scholarly journals Clinimetallomics: Arsenic Speciation in Urine from Patients With Arsenism by HPLC-ICP-MS

2021 ◽  
Vol 42 (5) ◽  
Author(s):  
Huiling Li
Keyword(s):  
Arsenic Speciation ◽  
Speciation Analysis ◽  
Arsenic Species ◽  
The Body ◽  
Urine Samples ◽  
Clinical Samples ◽  
Total Arsenic ◽  
Arsenic Poisoning ◽  
Icp Ms

Clinimetallomics is proposed as a branch of metallomics that focuses on the study of the metallome in clinical samples of urine, blood, and tissues. As the clinical diagnosis of arsenic poisoning is mainly based on the concentration of total arsenic in urine, the toxicity of arsenic varies greatly in different speciation. Analysis of arsenic speciation with excessive total arsenic in urine can provide a basis for precise treatment. It can also be used to understand the fate of arsenic in the body of patients with arsenic poisoning after treatment with sodium dimercaptopropane sulfonate. In this study, a HPLC-ICP-MS method was established for the determination of arsenic species in urine samples from patients diagnosed with arsenism. Use the established method to detect urine samples, which can be directly assayed after simple sample dilution with 20 mmol/L EDTA-2Na. With the concentration of arsenic speciation in the range of 1.0~100.0 ng/mL, the linear correlation coefficient was higher than 0.99996. The recoveries were between 92.4% and 109.0%. The precision of the concentration and retention time (n = 3) were less than 3.0% and 0.3%, respectively, and the detection limit was between 1.42 ng/mL and 1.86 ng/mL. This method can be applied to arsenic speciation in the urine of healthy people, in patients treated for arsenic poisoning, and in patients diagnosed with arsenism.

scholarly journals Determination of total arsenic content and arsenic speciation in different types of rice

2017 ◽  
Vol 26 (1) ◽  
pp. 293-298 ◽  
Author(s):  
Sang Ryun Yim ◽  
Ga Young Park ◽  
Kwang Won Lee ◽  
Myung-Sub Chung ◽  
Soon-Mi Shim
Keyword(s):  
Arsenic Speciation ◽  
Arsenic Content ◽  
Total Arsenic ◽  
Different Types

scholarly journals Characterization of arsenic in dried baby shrimp (Acetes sp.) using synchrotron-based X-ray spectrometry and LC coupled to ICP-MS/MS

2018 ◽  
Vol 33 (10) ◽  
pp. 1616-1630 ◽  
Author(s):  
Diana Guimarães ◽  
Austin A. Roberts ◽  
Mina W. Tehrani ◽  
Rong Huang ◽  
Louisa Smieska ◽  
...  
Keyword(s):  
Arsenic Content ◽  
Total Arsenic ◽  
Portable Xrf ◽  
X Ray ◽  
As Species ◽  
Icp Ms

Total arsenic content of dried baby shrimp was quantified using portable XRF and ICP-MS, and characterized further by SR-μXRF, with the major As species identified using μXANES, and confirmed by LC-ICP-MS/MS.

Determination of total arsenic and arsenic speciation in tobacco products: from tobacco leaf and cigarette smoke

2011 ◽  
Vol 26 (8) ◽  
pp. 1633 ◽  
Author(s):  
Sutthinun Taebunpakul ◽  
Chuan Liu ◽  
Christopher Wright ◽  
Kevin McAdam ◽  
Julien Heroult ◽  
...  
Keyword(s):  
Cigarette Smoke ◽  
Arsenic Speciation ◽  
Total Arsenic ◽  
Tobacco Products ◽  
Tobacco Leaf

scholarly journals Arsenic-Related Health Risk Assessment of Realgar-Containing NiuHuangJieDu Tablets in Healthy Volunteers Po Administration

2022 ◽  
Vol 12 ◽  
Author(s):  
Xiao Wu ◽  
Ruoning Yan ◽  
Rong Guan ◽  
Yi Du ◽  
Yuexin Liu ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Healthy Volunteers ◽  
Arsenic Speciation ◽  
Arsenic Exposure ◽  
Hydride Generation ◽  
Atomic Fluorescence Spectrometry ◽  
Total Arsenic ◽  
Atomic Fluorescence

Realgar, an arsenic-containing traditional Chinese medicine of As2S2, has significant therapeutic effects for hundreds of years. NiuHuangJieDu tablets (NHJDT) is one of the most commonly prescribed realgar-containing preparations for the treatment of sore throat, swelling, and aching of gums. However, realgar-containing TCMs raise great safety concerns due to the adverse effects reported by arsenic poisoning. In this study, the arsenic-related health risk assessment of NHJDT was conducted in healthy volunteers after single and multiple doses oral administration. Blood, plasma, and urine samples were collected after dosing at predetermined time points or periods. Simple, rapid, and sensitive methods were established for the quantification of total arsenic and arsenic speciation in biological samples. The total arsenic and arsenic speciation were determined by hydride generation-atomic fluorescence spectrometry (HG-AFS) and high-performance liquid chromatography–hydride generation–atomic fluorescence spectrometry (HPLC-HG-AFS), respectively. No significant fluctuation of total arsenic was observed in human blood, and no traces of arsenic speciation were found in human plasma. Dimethylarsenic acid was detected as the predominated arsenic species in human urine after dosing. Therapeutic dose administration of NHJDT was relatively safe in single dose for the limited blood arsenic exposure, but long-term medication may still pose health risks due to the accumulation of arsenics in blood and its extremely slow excretion rate. Therefore, arsenic exposure should be carefully monitored during realgar-containing TCM medication, especially for long-term regimen. The results obtained in this study will provide scientific references for the clinical application of realgar and its-containing TCMs.

scholarly journals Nano-sized zeolites as modulators of thiacloprid toxicity onChironomus riparius

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3525 ◽  
Author(s):  
Carla S. Lorenz ◽  
Anna-Jorina Wicht ◽  
Leyla Guluzada ◽  
Barbara Crone ◽  
Uwe Karst ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Imaging Techniques ◽  
Toxicity Tests ◽  
Biting Midge ◽  
Ms Imaging ◽  
Icp Ms ◽  
Small Primary ◽  
Acute Toxicity Tests ◽  
Investigation Period ◽  
Adsorption Rates

This study investigated whether zeolites of different size (Y30 (nano-sized) and H-Beta(OH)-III (forming large aggregates/agglomerates composed of 50 nm small primary particles)) exerted acute toxicity on larvae of the non-biting midge,Chironomus riparius, and whether such zeolites are able to modulate the toxicity of a common insecticide, thiacloprid, by means of adsorption of a dissolved toxicant. We conducted acute toxicity tests with fourth instar larvae ofC. riparius. In these tests, larvae were exposed to zeolites or thiacloprid solely, or to mixtures of both compounds. The mixtures comprised 1.0 µg/L thiacloprid in addition to low (5.2 mg/L), medium (18.2 mg/L), and high (391.7 mg/L) zeolite concentrations, resulting in different adsorption rates of thiacloprid. As biological endpoints, changes in mortality rates and in behavior were monitored every 24 h over a total investigation period of 96 h. Furthermore, we conducted chemical analyses of thiacloprid in the medium and the larvae and located the zeolite particles within the larvae by LA-ICP-MS imaging techniques. Our results demonstrate that both types of zeolites did not exert acute toxicity when applied as single-substances, but led to reduced acute toxicity of thiacloprid when applied together with thiacloprid. These results are in line with the sorption properties of zeolites indicating reduced bioavailability of thiacloprid, although our data indicate that thiacloprid can desorb from zeolites to some extent. While freely dissolved (i.e., non-sorbed) fraction of thiacloprid was a good parameter to roughly estimate toxic effects, it did not correlate with measured internal thiacloprid concentrations. Moreover, it was shown that both zeolite types were ingested by the larvae, but no indication for cellular uptake of them was found.

scholarly journals The use of L-ascorbic acid in speciation of arsenic compounds in drinking water

2009 ◽  
pp. 165-175 ◽  
Author(s):  
Aleksandar Stanic ◽  
Sasa Jovanic ◽  
Nikola Marjanovic ◽  
Zvonimir Suturovic
Keyword(s):  
Ascorbic Acid ◽  
Atomic Absorption Spectrometry ◽  
Atomic Absorption ◽  
Ph Value ◽  
Arsenic Speciation ◽  
Hydride Generation ◽  
Reaction Medium ◽  
Absorption Spectrometry ◽  
Arsenic Content ◽  
Arsonic Acid

Arsenic speciation, besides total arsenic content determination, is very important in analysis of water, foodstuffs, and environmental samples, because of varying degrees of toxicity of different species. For such purpose hydride generation atomic absorption spectrometry can be used based on the generation of certain types of hydride, depending on the pH value and pretreatment in different reaction media. In this study, we have investigated the effect of L-ascorbic acid as the reaction medium as well as the pre-reducing agent in speciation of arsenic by hydride generation-atomic absorption spectrometry in order to determine monomethyl arsonic acid (MMA) in the presence of inorganic forms of arsenic.

scholarly journals Silicon speciation in light petroleum products using gas chromatography coupled to ICP-MS/MS

2020 ◽  
Vol 35 (10) ◽  
pp. 2387-2394
Author(s):  
Raquel Sánchez ◽  
Fabien Chainet ◽  
Vincent Souchon ◽  
Sylvain Carbonneaux ◽  
Charles-Philippe Lienemann ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Petroleum Products ◽  
Chemical Form ◽  
Light Petroleum ◽  
Detector Response ◽  
Tandem Mass ◽  
Chromatography Method ◽  
Sample Matrix ◽  
Icp Ms

A gas chromatography method coupled to ICP-tandem mass spectrometry (GC-ICP-MS/MS) was validated for silicon speciation method for light petroleum products with a detector response independently of sample matrix and silicon chemical form.

Sign in / Sign up

Export Citation Format

Share Document