Biologically Active Co(II) and Ni(II) Complexes of
N-(2-Thienylmethylene)-2-Aminothiadiazole
Keyword(s):
Co(II) and Ni(II) complexes Schiff base, N-(2-thienylmethylene)-2-aminothiadiazole have been prepared and characterized by their physical, spectral and analytical data. The title Schiff-base acts as NNS donor tridentate during the complexation reaction with these metal ions having a composition, [M(L)2]Xn where M=Co(II) or Ni(II), L=, X=NO3− , SO42− , C2O42− or CH3CO2− and n=1 or 2 and show an octahedral geometry. In order to evaluate the effect anions upon chelation, the Schiff-base and its new complexes have been screened for their antibacterial activity against bacterial strains e.g., Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa.
2020 ◽
pp. 14-21