scholarly journals Anthill Inhibiting Bacteria, a Promising Source of Bio Efficacy

2020 ◽  
pp. 14-21
Author(s):  
A. A. Katun ◽  
A. R. Abdulmumin ◽  
M. U. Yahaya ◽  
N. K. Habeeb ◽  
A. Bala
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Salmonella Typhi ◽  
Biologically Active ◽  
Bacterial Strains ◽  
Active Metabolites ◽  
Bacillus Lentus ◽  
Total Prevalence ◽  
Promising Source ◽  
And Staphylococcus Aureus

The investigation into soil bacteria has been widely studied and becoming increasingly appreciated as an exceptional reservoir of unique naturally occurring biologically active metabolites with pharmaceutical applications. This article aimed to isolate, identify and biochemically characterize antibiotic-producing bacteria from anthill soils in the permanent site of Ibrahim Badamasi Babangida University, Lapai (IBBUL), Niger State, Nigeria. The sum of ten samples were collected from five sampling sites, the sampling was done in threefold (morning, noon and evening) and analyzed adopting standard microbiological protocols. The obtained result revealed that the total bacteria count in the morning ranges from 2.1×107 cfu/mL to 1.4×106 cfu/mL, noon count ranges from 3.1×107 to 2.6×106 cfu/mL while evening count was in the range of 2.1×107 cfu/mL to 1.7×106 cfu/mL. A total number of five (5) bacteria were isolated as Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Bacillus lentus and Micrococcus reseus. The total prevalence of the bacterial isolates in the morning, noon and evening were calculated as B. subtilis (109.08%), S. epidermidis (36.36%), M. reseus (36.36%), B. lentus (63.63%), and S. aureus (54.54%) respectively. These isolates were further assayed against Escherichia coli, Salmonella typhi, Klebsiella sp. and Staphylococcus aureus. The antibacterial outcome showed that two (2) (40%) anthill isolates exhibited antibacterial activity against three (3) tested bacteria (Escherichia coli, Salmonella typhi and Staphylococcus aureus). This research study has showcased that the production of inhibitory substances are common among some of the bacterial strains isolated from anthills.

Ferrocene-Based Antibacterial Agents: Synthesis, Characterization, and Biological Evaluation of Metal (II) Complexes with Glycine-Derived Compounds

2011 ◽  
Vol 339 ◽  
pp. 317-320 ◽  
Author(s):  
Yu Ting Liu ◽  
Xiao Ming Sun ◽  
Da Wei Yin
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Antibacterial Agents ◽  
Salmonella Typhi ◽  
Biological Evaluation ◽  
Bacterial Strains ◽  
Gram Negative ◽  
And Staphylococcus Aureus

A series of Ferrocene Schiff bases derived from glycine and their cobalt (II), copper (II), nickel (II), and zinc (II) metal complexes have been synthesized and characterized by IR, 1H NMR, MS and elemental analysis, the results conformed well with expected structures. The synthesized ligands, along with their metal (II) complexes, were screened in vitro for their antibacterial activity against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains. The results showed that the metal (II) complexes are more potent in antibacterial activity against one or more species in comparison with those of uncomplexed ligands.

Synthesis, Characterization and Antimicrobial Activity of Bis-Acetylferrocene Schiff Base

2011 ◽  
Vol 396-398 ◽  
pp. 1875-1878 ◽  
Author(s):  
Yu Ting Liu ◽  
Hai Long Guo ◽  
Da Wei Yin
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Salmonella Typhi ◽  
Bacterial Strains ◽  
Gram Negative ◽  
And Staphylococcus Aureus

Three bis-acetylferrocene schiff bases have been synthesized and characterized by IR, 1H NMR, and elemental analysis, the results conformed well with expected structures. The synthesized compounds were screened in vitro for their antimicrobial activity against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains. The results showed that these compounds are show excellent antimicrobia activities against Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi ,Bacillus subtilis,Staphylococcus aureus.

scholarly journals Pharmacological Role of Anions (Sulphate, Nitrate, Oxalate and Acetate) on the Antibacterial Activity of Cobalt(II), Copper(II) and Nickel(II) Complexes With Nicotinoylhydrazine-Derived ONO, NNO and SNO Ligands

1996 ◽  
Vol 3 (5) ◽  
pp. 211-217 ◽  
Author(s):  
Zahid Hussain Chohan ◽  
Abdur Rauf
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Metal Ion ◽  
Bacterial Species ◽  
Biologically Active ◽  
Schiff Base Ligands ◽  
Mixed Ligands ◽  
And Staphylococcus Aureus

Mixed ligands biologically active complexes of cobalt(II), copper(II) and nickel(II) with nicotinoylhydrazine-derived ONO, NNO and SNO donor schiff-base ligands having the same metal ion but different anions such as sulphate, nitrate, oxalate and acetate have been synthesised and characterised on the basis of their physical, analytical and spectral data. In order to evaluate the role of anions on their bioability, these ligands and their synthesised metal complexes with various anions have been screened against bacterial species such as Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus and the title studies have proved a definative role of anions in increasing the biological activity

scholarly journals Uji Aktivitas Antimikroba Ekstrak n-Butanol Madu Hutan (Apis nigrocincta) dari Kabupaten Selayar dengan Metode KLT-Bioautografi

2020 ◽  
Vol 1 (2) ◽  
pp. 41-45
Author(s):  
A.Suparlan Isya Syamsu
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Staphylococcus Epidermidis ◽  
Salmonella Typhi ◽  
Test Results ◽  
Butanol Extract ◽  
Apis Nigrocincta ◽  
And Staphylococcus Aureus

Preliminary research has been conducted on the antimicrobial activity of n-Butanol extract of forest honey (Apis nigrocincta). This study aims to determine the antimicrobial activity of forest honey from Selayar Regency on the growth of test microbes, using the method of solid dilution with the test microbial Bacillus subtilis, Staphylococcus aureus, Streptococcus mutans, Pseudomonas aeruginosa, Salmonella typhi, Escherichia coli, Vibrio sp, Staphylococcus epidermidis, and Candida albicans against n-butanol extract from forest honey (Apis nigrocincta) at 1 mg/ml. The results obtained showed that n-butanol extract inhibited the growth of bacteria Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus aureus. To estimate the compounds that provide antimicrobial activity, the TLC-Bioautography test is performed. Obtained the best results from the separation of compounds by TLC using Chlorophorom eluate: Acetone (3: 1). The TLC-Bioautographic test results showed that the spots with an Rf value of 0.29 gave activity to Bacillus subtilis, Escherichia coli, and Staphylococcus epidermidis, and gave positive results on the appearance of flavonoid compounds.

scholarly journals Antidiarrheal Activity of The Combination of Ethanol Extracts of Turmeric Rhizomes, Gall oak Leaves, Guava Leaves and Meniran Herbs

2017 ◽  
Vol 2 (3) ◽  
pp. 96-101
Author(s):  
Sumi Wijaya ◽  
Lisa Soegianto
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Diarrheal Disease ◽  
Shigella Flexneri ◽  
Salmonella Typhi ◽  
Shigella Dysenteriae ◽  
Antidiarrheal Activity ◽  
Guava Leaves ◽  
Oak Leaves ◽  
And Staphylococcus Aureus

Diarrheal disease is an endemic disease in Indonesia and also a potential disease that can cause death. In practice, the use of traditional medicines derived from plants still being considered by society due to its viability, economic factors and safety reasons. Several plants worked as antidiarrheal agents with the mechanism actions of (1) antibacterial (inhibited the growth of Escherichia coli, Shigella dysenteriae, Shigella flexneri, Staphylococcus aureus and Salmonella Typhi); (2) reduced the contraction of intestinal as results in the reduction of pain and the reduction of frequency of defecation or; (3) both mechanism of actions. Thus the purpose of the present study is to evaluate antidiarrheal activity of the combination of plant extracts which have been proved to have antidiarrheal activity.  Turmeric (Curcuma domestica) rhizomes, gall oak (Quercus lusitanica) leaves, guava (Psidium guajava) leaves and meniran (Phyllanthus niruri) herbs were used for this combination. The purpose of this combination was to minimize the doses (based on literature reviews turmeric at 5% and Meniran 10% inhibited the growth of Escherichia coli and Staphylococcus aureus, meanwhile guava leaves at 150 mg/kg BW and gall oak leaves at 10% reduced diarrhea in animal tested). Maceration was chosen for the extraction method using ethanol 96% as the solvent. Protection and transit intestinal method with loperamide HCl as comparison drug and castor oil for the induction of diarrhea were used for antidiarrheal activity, meanwhile diffusion and dilution methods using, inhibition zones, minimum inhibition concentration and minimum bactericidal concentration parameters were used for antibacterial activity. Tetracycline HCl with the concentration of 30 µg was used for the control. The results revealed that the combination of plant extract with the doses of 200 mg/KgBW (1:1:1:1) reduced diarrhea in mice with relaxation of smooth muscle and showed weak antibacterial effects on Eschericia coli and Staphylococcus aureus but strongly inhibited the growth of Salmonella Typhi.

Ferrocene-Based with Thiadiazole Antibacterial Agents: Synthesis, Characterization, and Biological Evaluation

2012 ◽  
Vol 189 ◽  
pp. 181-184
Author(s):  
Da Wei Yin ◽  
Xiao Ming Sun ◽  
Yu Ting Liu
Keyword(s):  
Escherichia Coli ◽  
Antibacterial Activity ◽  
Antibacterial Agents ◽  
Salmonella Typhi ◽  
Biological Evaluation ◽  
New Drugs ◽  
Bacterial Strains ◽  
Gram Negative ◽  
And Staphylococcus Aureus

A series of ferrocene schiff bases derived from Thiadiazole have been synthesized and characterized by IR, 1H NMR, and elemental analysis, the results conformed well with expected structures. The synthesized compounds were screened in vitro for their antibacterial activity against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains. The results showed that these compounds are a series potential new drugs in antibacterial activity against one or more species.

scholarly journals Modulating antibacterial activity against multidrugresistant Escherichia coli and Staphylococcus aureus of the flavonoid pectolinarin isolated from Lantana camara leaves

2021 ◽  
Vol 10 (6) ◽  
pp. 217-220
Author(s):  
Maria Regivânia Xavier ◽  
Aluísio Marques da Fonseca ◽  
Beatriz Gonçalves Cruz ◽  
Antonia Mayara dos Santos Mendes ◽  
Larissa Santos Oliveira ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Natural Compound ◽  
Multidrug Resistant ◽  
Antagonistic Effect ◽  
Antibacterial Drug ◽  
Bacterial Strains ◽  
Gram Positive ◽  
And Staphylococcus Aureus

The antibiotic potentiating activity against standard and multidrug-resistant Escherichia coli and Staphylococcus aureus bacterial strains of the natural compound 5”-O-α-L-raminopyranosyl-1’-β-D-glycopyranosyl-4’,6-dimethoxyflavone (pectolinarin) isolated from L. camara leaves was evaluated. Tests for antibacterial activity of the pure natural substance and analysis of the potentiation of antibacterial activity of pectolinarin associated with antibiotics were carried out against standard and multiresistant bacterial strains of Escherichia coli and Staphylococcus aureus by microdilution. Pectolinarin, when combined with the antibiotic gentamicin, showed synergism, potentiating growth inhibition against Gram-positive S. aureus strains. The pectolinarin flavonoid when combined with the gentamicin antibiotic potentiated its action Gram-positive S. aureus bacteria. Moreover, an antagonistic effect was observed when the pectolinarin was combined with the penicillin antibiotic against the multiresistant S. aureus 358 strain. This research suggests that pectolinarin is a compound with potential application as an antibacterial drug.

scholarly journals Antibacterial activity of the bacteriocins producing- lactic acid bacteria isolated from some processed meat products against selected indicator bacterial strains

2021 ◽  
Vol 12 (2) ◽  
pp. 640-645
Author(s):  
Huda M Selman ◽  
Ahmed A Mahdi ◽  
Nagat A El Rofaei ◽  
Elnasri M Mutwali
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Meat Products ◽  
Salmonella Typhi ◽  
Diffusion Method ◽  
Processed Meat ◽  
Bacterial Strains ◽  
Central Public Health

In this study, a total of 25 Lactic Acid Bacteria (LAB) isolates from 15 samples [4 burgers, 4frankfurters, 3 pastramis, 2 sausages and 2baby faeces] were screened for their ability to produce inhibitory substances against three microorganisms which were isolated from meat products: (Salmonella typhi, Staphylococcus aureus and Escherichia coli). Other indicators (reference target organisms) were obtained from the Central Public Health Laboratory, Khartoum State, Sudan. These were: Salmonella typhi ATCC14023, Staphylococcus aureus ATCC29213 and Escherichia coli ATCC25922. The antagonistic activities of the isolates were screened by the direct spot-on-lawn method and well- diffusion method. A total of 25 isolates of LAB were obtained, 15 of which produced promising inhibition zones against all or some of the indicator bacterial strains.

scholarly journals Antibacterial Activity of Haematococcus pluvialis Crude Astaxanthin Extract

2021 ◽  
Vol 11 (2-S) ◽  
pp. 28-30
Author(s):  
Ashaq Hussain Rather ◽  
Surendra Singh ◽  
Sameer Choudhary
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Haematococcus Pluvialis ◽  
Salmonella Typhi ◽  
Vibrio Cholera ◽  
Potential Source ◽  
Crude Extracts ◽  
And Staphylococcus Aureus

H. pluvialis is the potential source of natural astaxanthin, which is considered as super antioxidant. In the present investigation, astaxanthin was extracted from the encysted cells of H. pluvialis with acetone, methanol, DMSO and hexane, the crude extracts were tested for four strain (Escherichia coli, Salmonella typhi, Vibrio cholera and Staphylococcus aureus)of bacteria for the antibacterial activity. Highest antibacterial activity was observed as 10.2 ±0.20 mm extracted with acetone on Escherichia coli while as least antibacterial activity was found as6.1±0.0 mm extracted with hexane on Vibrio cholera. Keywords: Haematoccoccus pluvialis; Astaxanthin; Antibacterial.

scholarly journals Phytochemical Evaluation and Antibacterial Activity of Fruit Extract of Solanum surattense Burm F. against Some Pathogenic Bacteria

2020 ◽  
Vol 13 (1) ◽  
pp. 79-87
Author(s):  
R Dhanalakshmi ◽  
J JaffarIqbal ◽  
Nausath Jabeen K ◽  
Noorul Zaithun Hidhaya M ◽  
K Meena ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacillus Subtilis ◽  
Inhibitory Concentration ◽  
Minimum Bactericidal Concentration ◽  
Salmonella Typhi ◽  
Bacterial Strains ◽  
Hydroalcoholic Extract ◽  
Solanum Surattense

The objective of this study was to evaluate phytochemical constituents and antibacterial activity of hydroalcoholic extract of Solanum surattense fruit against some grampositive and gram-negative bacterial strains. The evaluation of antibacterial activity was carried out by using the disc diffusion method, determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Ciprofloxacin was used as positive control. Hydroalcoholic extract of Solanum surattense fruit containing alkaloids, flavonoids, phenol, saponins, terpenoids, glycosides, sterols, proteins and tannins. Efficacy data analysis showed that hydroalcoholic extracts of fruit of Solanum surattense (1 mg/ml) inhibited the growth of Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi with mean diameters of inhibition zones being 24, 25, 28 and 30 mm respectively. On the other hand, minimum inhibitory concentration and minimum bactericidal concentration value of 0.062 and 0.25 mg/ml, 0.062 and 0.25 mg/ml, 0.312 and 0.125 mg/ml, 0.156 and 0.0312 mg/ml were recorded against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi respectively. Hydroalcoholic extracts of Solanum surattense fruit have potent antibacterial activity against the different tested bacterial strains. This activity supports their use in treatment of infections caused by such resistant bacteria.

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