Urinary Excretion of Inorganic Pyrophosphate by Normal Subjects and Patients with Renal Calculi in North-Western India and the Effect of Diclofenac Sodium upon Urinary Excretion of Pyrophosphate in Stone Formers

1992 ◽  
Vol 48 (4) ◽  
pp. 404-408 ◽  
Author(s):  
S. Sharma ◽  
S. Vaidyanathan ◽  
S.K. Thind ◽  
R. Nath
Keyword(s):  
Urinary Excretion ◽  
Diclofenac Sodium ◽  
Renal Calculi ◽  
Normal Subjects ◽  
Western India ◽  
Inorganic Pyrophosphate ◽  
Stone Formers ◽  
North Western

Study of Circadian Rhythmicity of Urinary Excretion of Glycosaminoglycans in Normal Subjects and Stone Formers

Urolithiasis ◽  
1989 ◽  
pp. 243-243
Author(s):  
H. Sidhu ◽  
S. Vaidyanathan ◽  
A. K. Hemal ◽  
S. K. Thind ◽  
R. Nath ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Normal Subjects ◽  
Circadian Rhythmicity ◽  
Stone Formers

The Influence of Glucose and Crude Fibre (Wheat Bran) on the Rate of Intestinal 47Ca Absorption The Influence of Glucose and Wheat Bran on Calcium Absorption

1979 ◽  
Vol 65 (3) ◽  
pp. 143-146
Author(s):  
M. A. Macleod ◽  
N. J. Blacklock
Keyword(s):  
Urinary Excretion ◽  
Wheat Bran ◽  
Calcium Absorption ◽  
Normal Subjects ◽  
Calcium Balance ◽  
Theoretical Possibility ◽  
Crude Fibre ◽  
Calcium Stone ◽  
Negative Calcium Balance ◽  
Stone Formers

AbstractWith evidence of induction of increased urinary excretion of calcium by the ingestion of glucose and sucrose there is the theoretical possibility in these circumstances of at least a transient negative calcium balance. In this study the ingestion of glucose or glucose equivalent was found to stimulate 47Ca absorption from the intestine both in normal subjects and in idiopathic calcium stone formers. This induced increase in the rate of 47Ca absorption by glucose can be negated by the addition of crude fibre in the form of wheat bran.

Chronobiology of urinary citrate excretion amongst stone-formers and healthy males from North Western India

1991 ◽  
Vol 19 (3) ◽  
pp. 203-206 ◽  
Author(s):  
D. Wangoo ◽  
S. K. Thind ◽  
G. S. Gupta ◽  
R. Nath
Keyword(s):  
Western India ◽  
Stone Formers ◽  
Urinary Citrate ◽  
North Western ◽  
Healthy Males

ÉTUDES IN VIVO SUR LE MÉTABOLISME DES ANDROGÉNES APRES ADMINISTRATION DE STÉROÏDES INHIBITEURS DE L'OVULATION

1965 ◽  
Vol 50 (1) ◽  
pp. 131-144 ◽  
Author(s):  
P. Mauvais-Jarvis ◽  
M. F. Jayle ◽  
J. Decourt ◽  
J. Louchart ◽  
J. Truffert
Keyword(s):  
Luteinizing Hormone ◽  
Urinary Excretion ◽  
Normal Subjects ◽  
Hormone Activity ◽  
Testosterone Production ◽  
Normal Men ◽  
Ethinyl Oestradiol

ABSTRACT Normal subjects and hirsute women with micropolycystic ovaries were treated with ethinyl-oestrenol + 3-methoxy-ethinyl-oestradiol (Lyndiol®), in view of studying the action of this compound on the production of androgens and on the urinary excretion of their metabolites. In normal men, the production of testosterone and the excretion of androsterone and aetiocholanolone are suppressed, whereas the excretion of other 17-ketosteroids and the production of dehydroepiandrosterone sulphate are unchanged. Moreover, the luteinizing hormone activity (LH) in plasma is depressed. It seems that the preparation inhibits specifically the testicular androgen production, by suppressing the hypothalamo-hypophyseal control of LH. Testosterone production and urinary 17-ketosteroid excretion are modified in the same way in women with Stein-Leventhal's syndrome. Physiopathological and therapeutical implications which come from these results are discussed.

A COMPARISON OF TWO METHODS FOR MEASUREMENT OF ALDOSTERONE SECRETION RATE IN MAN

1966 ◽  
Vol 53 (2) ◽  
pp. 177-188 ◽  
Author(s):  
P. Lund-Johansen ◽  
T. Thorsen ◽  
K. F. Støa
Keyword(s):  
Urinary Excretion ◽  
Normal Subjects ◽  
Secretion Rate ◽  
Aldosterone Secretion ◽  
Simple Method ◽  
Mean Values ◽  
Pathological Conditions ◽  
Significant Difference ◽  
Derivative Method ◽  
The Mean

ABSTRACT A comparison has been made between (A), a relatively simple method for the measurement of aldosterone secretion rate, based on paper chromatography and direct densitometry of the aldosterone spot and (B) a more elaborate isotope derivative method. The mean secretion rate in 9 normal subjects was 112 ± 26 μg per 24 hours (method A) and 135 ± 35 μg per 24 hours (method B). The »secretion rate« in one adrenalectomized subject after the intravenous injection of 250 μg of aldosterone was 230 μg per 24 hours (method A) and 294 μg per 24 hours (method B). There was no significant difference in the mean values, and correlation between the two methods was good (r = 0.80). It is concluded that the densitometric method is suitable for clinical purposes as well as research, being more rapid and less expensive than the isotope derivative method. Method A also measures the urinary excretion of the aldosterone 3-oxo-conjugate, which is of interest in many pathological conditions. The densitometric method is obviously the less sensitive and a prerequisite for its use is an aldosterone secretion of 20—30 μg per 24 hours. Lower values are, however, rare in adults.

Gastrointestinal Protective Effect of Zizyphus xylopyrus (Retz) Willd Leaf Extract Against Indomethacin and HCl-EtOH Induced Ulcers

2019 ◽  
Vol 5 (2) ◽  
pp. 140-146
Author(s):  
Shweta Jain ◽  
Sourabh Jain ◽  
Nagendra S. Chauhan ◽  
Ankur Vaidya
Keyword(s):  
Protective Effect ◽  
Ethanolic Extract ◽  
Negative Control ◽  
Gastric Epithelium ◽  
Gastric Ulcers ◽  
Western India ◽  
Skin Infections ◽  
Ulcer Index ◽  
Digestive Disorders ◽  
North Western

Background: Zizyphus xylopyrus (Retz.) Willd. (Rhamnaceae) is a straggling shrub or a small tree, armed with spines, found throughout north western India, Pakistan and China. Methods: The aerial and root barks, leaves and fruits of Zizyphus species are used in medicine for the treatment of various diseases such as weakness, liver complaints, obesity, diabetes, skin infections, fever, diarrhea, insomnia and digestive disorders. Ethanolic extract of leaves of Zizyphus xylopyrus (Retz) Willd was prepared by solvent extraction and subjected to study the protective effect against Indomethacin and HCl-EtOH induced ulcer using Ranitidine (100 mg/kg) and Omeprazole (8 mg/kg) as standard respectively. Results: Histopathological lesions with marked disorientation of the gastric epithelium was observed in negative control, while extract treated rats showed a better protected mucosa with intact epithelium in comparison to standard treated rats. Ulcer index and percentage ulcer protection also represent protecting effects of the extract. Conclusion: Ethanolic extract of Z. xylopyrus (Retz) Willd leaves extract was found to be significantly protective against gastric ulcers.

scholarly journals Excretion of urine extracellular vesicles bearing markers of activated immune cells and calcium/phosphorus physiology differ between calcium kidney stone formers and non-stone formers

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jiqing Zhang ◽  
Sanjay Kumar ◽  
Muthuvel Jayachandran ◽  
Loren P. Herrera Hernandez ◽  
Stanley Wang ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Calcium Oxalate ◽  
Extracellular Vesicles ◽  
Immune Cells ◽  
Kidney Stone ◽  
Fibroblast Growth Factor 23 ◽  
Pathogenic Mechanisms ◽  
Phosphorus Excretion ◽  
Stone Formers ◽  
Calcium Phosphorus

Abstract Backgrounds: Previous studies have demonstrated that excretion of urinary extracellular vesicles (EVs) from different nephron segments differs between kidney stone formers and non-stone formers (NSFs), and could reflect pathogenic mechanisms of urinary stone disease. In this study we quantified selected populations of specific urinary EVs carrying protein markers of immune cells and calcium/phosphorus physiology in calcium oxalate stone formers (CSFs) compared to non-stone formers (NSFs). Methods Biobanked urine samples from CSFs (n = 24) undergoing stone removal surgery and age- and sex- matched NSFs (n = 21) were studied. Urinary EVs carrying proteins related to renal calcium/phosphorus physiology (phosphorus transporters (PiT1 and PiT2), Klotho, and fibroblast growth factor 23 (FGF23); markers associated with EV generation (anoctamin-4 (ANO4) and Huntington interacting protein 1 (HIP1)), and markers shed from activated immune cells were quantified by standardized and published method of digital flow cytometry. Results Urine excretion of calcium, oxalate, phosphorus, and calcium oxalate supersaturation (SS) were significantly higher in CSFs compared to NSFs (P < 0.05). Urinary excretion of EVs with markers of total leukocytes (CD45), neutrophils (CD15), macrophages (CD68), Klotho, FGF23, PiT1, PiT2, and ANO4 were each markedly lower in CSFs than NSFs (P < 0.05) whereas excretion of those with markers of monocytes (CD14), T-Lymphocytes (CD3), B-Lymphocytes (CD19), plasma cells (CD138 plus CD319 positive) were not different between the groups. Urinary excretion of EVs expressing PiT1 and PiT2 negatively (P < 0.05) correlated with urinary phosphorus excretion, whereas excretion of EVs expressing FGF23 negatively (P < 0.05) correlated with both urinary calcium and phosphorus excretion. Urinary EVs with markers of HIP1 and ANO4 correlated negatively (P < 0.05) with clinical stone events and basement membrane calcifications on papillary tip biopsies. Conclusions Urinary excretion of EVs derived from specific types of activated immune cells and EVs with proteins related to calcium/phosphorus regulation differed between CSFs and NSFs. Further validation of these and other populations of urinary EVs in larger cohort could identify biomarkers that elucidate novel pathogenic mechanisms of calcium stone formation in specific subsets of patients.

Studies on the origin, evolution, and distribution of the Gramineae. III. The tribes of the subfamily Eragrostoideae

1960 ◽  
Vol 8 (3) ◽  
pp. 256 ◽  
Author(s):  
W Hartley ◽  
C Slater
Keyword(s):  
Wide Distribution ◽  
Western India ◽  
Distribution Maps ◽  
Winter Temperatures ◽  
Close Relationship ◽  
Hot Arid Climate ◽  
South West Africa ◽  
The Tropics ◽  
World Distribution ◽  
North Western

In further studies of grass distribution, maps are presented showing the world distribution of the Eragrosteae (sensu str.) and of the subfamily Eragrostoideae within which it is included. Both taxa show centres of high relative specific differentiation in inland Australia and in South West Africa, but in addition, the subfamily has centres of differentiation in the Sahara rekion, northern Mexico, and north-western India. The centres of differentiation are all in regions of hot, arid climate near the tropics of Cancer and Capricorn. The close relationship between climate and distribution is most apparent in the case of the subfamily Eragrostoideae, species of which are relatively abundant in the grass flora of all arid regions with high winter temperatures and summer or non-seasonal rainfall incidence. The distributions of most of the other tribes and subtribes which have been included in the Eragrostoideae show a similar relationship to climate. Some apparent exceptions to this are discussed, and it is shown that the geographical evidence supports conclusions from recent cytotaxonomic and anatomical studies that the taxa concerned should be removed from the subfamily. The very wide distribution of the subfamily and of its constituent taxa, as well as the close relationship between the distribution pattern and climate, suggests that the subfamily is a very old one. Geographical and taxonomic evidence indicates that it may have originated in tropical or subtropical Africa at least as early as the Oligocene.

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