scholarly journals Convalescent Blood: Current Perspective on the Efficacy of a Legacy Approach in COVID-19 Treatment

2021 ◽  
pp. 1-14
Author(s):  
Roghayeh Sheervalilou ◽  
Milad Shirvaliloo ◽  
Saman Sargazi ◽  
Soraiya Bahari ◽  
Ramin Saravani ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Unknown Origin ◽  
Cost Effective ◽  
Viral Disease ◽  
The Novel ◽  
New Approach ◽  
Current Perspective ◽  
Antiviral Medication ◽  
Novel Coronavirus ◽  
Almost All

Since early 2020, COVID-19 has wreaked havoc in many societies around the world. As of the present, the SARS-CoV-2-borne disease is propagating in almost all countries, affecting hundreds of thousands of people in an unprecedented way. As the name suggests, the novel coronavirus, widely known as SARS-CoV-2, is a new emerging human pathogen. A novel disease of relatively unknown origin, COVID-19 does not seem to be amenable to the currently available medicines since there is no specific cure for the disease. In the absence of any vaccine or effective antiviral medication, we have no tools at our disposal, but the method of quarantine, be it domestic or institutional, to hinder any further progression of this outbreak. However, there is a record of physicians in the past who practiced convalescent blood transfusion. To their awe, the method seemed to be useful. It is anticipated that these contemporary methods will outdo any other vaccination process in the time being, as blood transfusion is instead a cost-effective and time-friendly technique. Following a successful trial, this new approach of contemporary nature to a viral disease may serve as an emergency intervention to intercept infectious outbreaks and prevent an impending epidemic/pandemic. In this review, we document the most recent evidence regarding the efficiency of convalescent plasma and serum therapy on SARS, MERS, and particularly COVID-19, while discussing potential advantages and possible risks of such practice.

scholarly journals Respiratory Care in Corona

2021 ◽  
Vol 58 (2) ◽  
pp. 613-620
Author(s):  
Mustafa Amdani, Dr. Swaroopa Chakole
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Human Life ◽  
The Body ◽  
Respiratory Care ◽  
The Novel ◽  
Specific Therapy ◽  
History Of ◽  
Novel Coronavirus ◽  
Almost All ◽  
The Impact

BACKGROUND The expanse of the coronavirus disease 2019 or COVID-19 is huge. The impact is multispectral and affected almost all aspects of human life. SUMMARY Respiratory impact of the COVID-19 is the most felt and widely reported impact. As the novel coronavirus maintained its history of affecting lungs as seen previously in severe acute respiratory syndrome (SARS) outbreak. Ventilators and oxygen support system are required mostly in comorbid patients particularly amongpatientsbearing illnesses like asthma, bronchial impairment and so on. CONCLUSION More study needs to be done in order to assess the impact on the respiratory functioning of the body. Respiratory care must be including proper instruments so that more efficient result can be obtained. Research is needed to promote the invention of specific therapy for targeted action for respiratory functioning improvement.

scholarly journals The Novel Coronavirus 2019 (COVID-19): A Narrative Review

2020 ◽  
Vol 1 (2) ◽  
pp. 15-52
Author(s):  
Baratali Rezapour ◽  
Sayed Jalil Musavi ◽  
Faezeh Shirzadeh Maleki
Keyword(s):  
Food Chain ◽  
Signs And Symptoms ◽  
Viral Disease ◽  
Zoonotic Diseases ◽  
The Body ◽  
Behavioral Characteristics ◽  
The Novel ◽  
Ecological Characteristics ◽  
Novel Coronavirus ◽  
Key Steps

One of the key steps in determining how to prevent the viral disease is to identify the virus. The virus lives in different ways and in different environments. It lives in the air, in the sea, on plants, animals and objects and humans. Some people put humans on the path of developing zoonotic diseases that are specific to animals but also involve people with unhealthy behaviors. In the food chain, each animal is hunted by other animals and feeds on other animals or plants and other objects. Bacteriophages are viruses that kill bacteria. And there are creatures that kill viruses and this is the biological struggle with viruses. When the virus enters the body, it performs a series of activities that lead to a series of symptoms in the patient. These symptoms include the behavior of viruses. These are among the ecological and behavioral characteristics of viruses that need to be fully understood in order to limit viruses and deal with epidemics and pandemics. In this study, we try to reach a conclusion by reviewing the articles that have information about the behavioral (signs and symptoms) and ecological characteristics of viruses and use these findings in order to combat viruses.

The Impact of COVID-19 on Stock Markets

2022 ◽  
pp. 250-262
Author(s):  
Aslı Aybars ◽  
Mehtap Öner
Keyword(s):  
Literature Review ◽  
Financial Markets ◽  
Stock Returns ◽  
Empirical Studies ◽  
The Novel ◽  
The World ◽  
Fast Pace ◽  
Novel Coronavirus ◽  
Almost All ◽  
The Impact

The novel coronavirus, COVID-19, which emerged at the end of 2019 and spread to the world at a very fast pace, resulted in a pandemic affecting the finance industry besides many other industries though at varying extents. Financial markets, which can be regarded as cornerstones of each and every country's economic success, have been adversely influenced due to the fear and uncertainty arising with the emergence of the novel coronavirus at different degrees. This chapter provides a summary of a literature review based on the impact of this pandemic on stock returns and volatility in the stock exchanges of different countries and regions of the world. What has been captured as a result of this literature review is that almost all of the financial markets around the world have been influenced due to the virus. Further, industry-wise empirical studies demonstrate that not all industries are affected at the same level or even in the same direction.

Damage Detection for Simply Supported Beams Using Mid-Span Displacement Indicator

2010 ◽  
Vol 29-32 ◽  
pp. 1532-1536
Author(s):  
S.J. Zhang ◽  
Z.J. Ma
Keyword(s):  
Damage Detection ◽  
Direct Relationship ◽  
Cost Effective ◽  
Small Region ◽  
The Novel ◽  
New Approach ◽  
Simply Supported ◽  
Detection Approach ◽  
Damaged Beams ◽  
Local Stiffness

This paper investigates the detection of damage for simply supported beams to ensure their safety. Based on the analysis of possible kinds of damage may occur, this paper presents a new approach which relies on the fact that any change in local stiffness caused by damage can be reflected by the change of mid-span displacement between the intact and damaged beams. Direct relationship between the change in local stiffness and the measured mid-span displacement values is developed. This approach can identify the geometric locations of damage and then inspection means are used as a complement to find the real damage phenomena within the obtained small region. A numerical example is given to illustrate the feasibility and the effectiveness of the approach. The novel content offered by authors provides a simple, convenient, cost-effective, and nondestructive damage detection approach for simply supported beams.

scholarly journals Nanotechnology in Battle against CoViD-19: The Prevention, Diagnosis, and Treatment

2021 ◽  
Vol 10 (4) ◽  
pp. 2637-2645
Keyword(s):  
Detection Methods ◽  
Public Healthcare ◽  
The Novel ◽  
Healthcare Organizations ◽  
Dangerous Situation ◽  
Global Pandemic ◽  
Protection Devices ◽  
The Many ◽  
Novel Coronavirus ◽  
Almost All

People worldwide are experiencing the most dangerous situation concerning the novel severe acute respiratory syndrome known as coronavirus-2 (SARS-CoV-2), commonly referred to as the novel coronavirus disease-2019 (CoViD-19). Since late December 2019, an epidemic of coronavirus disease 2019 (CoViD-19) occurred in Wuhan, China, and rapidly spread to almost all parts of China. With the growing global burden of the CoViD-19 pandemic, scientists, researchers, and healthcare-related organizations constantly work for a viable vaccine or therapeutics, scalable detection methods, personal protection devices, and novel effective medical solutions. Nanotechnology has recently considerably addressed the many clinical and public healthcare issues that have emerged from the CoViD-19 pandemic. The main focus of this current review article is to explore the possibility and potential of nanotechnology to combat this global pandemic and ongoing mitigation techniques and strategies. Furthermore, novel nanotechnology-based products are currently being developed for the prevention, diagnostic, treatment of CoViD-19, which various researchers or healthcare organizations invent.

scholarly journals An overview of treatment options for COVID-19

2020 ◽  
Vol 9 (11) ◽  
pp. 1770
Author(s):  
Madhusmita Mohanty Mohapatra ◽  
Manju Rajaram ◽  
Dharm Prakash Dwivedi ◽  
Vishnukant Govindraj ◽  
Pratap Upadhya
Keyword(s):  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Treatment Options ◽  
Unknown Origin ◽  
The Novel ◽  
Clinical Trial Registry ◽  
Repurposed Drugs ◽  
Novel Coronavirus ◽  
Meta Analyses ◽  
Effective Drugs

Severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2) which emerged in Wuhan initially as pneumonia of unknown origin in December 2019, later spread to whole world and became pandemic on 11th March, 2020. Many drugs have been proposed but are backed without clinical evidence. Scientific bodies are in the row to discover a reliable vaccine and effective drugs against the novel coronavirus. Many antiviral and anti-parasitic drugs which were thought to have some effect on Coronavirus disease 2019 (COVID-19) have been tried during the crisis but none have shown concrete evidence of action. Randomized clinical trials on the repurposed drugs are now registered under clinical trial registry to look at the safety profile and efficacy of the drugs to be used against SARS-CoV-2. Many meta-analyses are being conducted worldwide to frame evidence for the fight against this novel coronavirus. We are providing below a review of various drugs that have been tried for treatment of COVID-19 as well as different clinical trials which are underway.

scholarly journals COVID-19 in Africa: The cost of perceived low incidence rates

2021 ◽  
Vol 2 (1) ◽  
pp. 050-054
Author(s):  
David Olufemi Adesanya ◽  
Precious Chidozie Azubuike
Keyword(s):  
Viral Disease ◽  
Information Management System ◽  
Incidence Rates ◽  
The Novel ◽  
African Countries ◽  
Care Workers ◽  
Low Incidence ◽  
Novel Coronavirus ◽  
The Cost ◽  
The Impact

COVID-19 is a viral disease caused by the novel coronavirus and has hit many countries of the world heavily. The impact of COVID-19 in Africa, is contrary to the experts and professional predictions. Most African have very poor healthcare systems, water supply, sanitary environment and other factors that are requisite to combating the spread of the virus. Reports on COVID-19 incidence from Africa may not be a true reflection of the actual situation. The poor health information management system predominant in most African countries and the inability to carry out effective testing for cases could be responsible for this reported low incidence rates. The implications of perceived low incidence constitute a burden to governments of nations, health care workers, educational and other institutions, communities, women and girls; as well as members of the population. As the virus spreads across Africa, there is a need to improve active case finding and report same to enable effective planning and resource mobilization towards containing the spread of the virus.

scholarly journals Microsurgical Reconstruction During Covid-19 Pandemic Setting: A Systematic Review and Clinical Applications

2021 ◽  
Vol 8 (1) ◽  
pp. 48-57
Author(s):  
Parintosa Atmodiwirjo ◽  
Mohamad Rachadian Ramadan ◽  
Nadhira Anindita Ralena ◽  
Sara Ester Triatmoko
Keyword(s):  
Breast Surgery ◽  
Neck Surgery ◽  
The Novel ◽  
Microsurgical Reconstruction ◽  
Safety And Health ◽  
Reconstructive Microsurgery ◽  
Novel Coronavirus ◽  
Almost All ◽  
Based Medicine ◽  
Multi Disciplinary Team

Introduction: The outbreak of the novel coronavirus disease 2019 (COVID-19) has taken almost all countries worldwide. This situation has compromised the safety and health of all medical workers, including microsurgeons. Given that there have been various articles published about the recommendations in microsurgical reconstruction during the COVID-19 pandemic, We felt compelled to compile all relevant studies about the microsurgical reconstruction in the COVID-19 pandemic setting, describe the various actions from different perspectives, as well as providing suggestions based on evidence-based medicine. Method: We did a systematic literature search using electronic databases such as PubMed, Embase, Medline, Wiley, and Cochrane using keywords reconstruction, Microsurgery, coronavirus, and COVID-19. All included studies were critically appraised and reviewed. Results: Nine relevant articles were included for the final review, four of them were qualitative studies, and 5 were guidelines. Studies look at various surgeon's experiences from different healthcare systems during the COVID-19 pandemic. The focuses of the included studies are also diverse from head and neck surgery, breast surgery, limb surgery, and general Reconstructive Microsurgery. Conclusion: Microsurgical reconstruction is not suggested to perform during the peak of the COVID-19 pandemic. It is indicated only if necessary after a rigorous review by the multi-disciplinary team. A full PPE, including a Powered Air Purifying Respirators (PAPR) system, fit-tested N95 respirator masks, face shield, and tight-fitting eye protection goggles, are recommended in performing the surgeries.

scholarly journals Nonlinear Markov Chain Modelling of the Novel Coronavirus (Covid-19) Pandemic

2020 ◽  
Author(s):  
Muammer Catak ◽  
Necati Duran
Keyword(s):  
Markov Chain ◽  
Markov Chains ◽  
Markov Chain Model ◽  
Chain Model ◽  
The Novel ◽  
The World ◽  
The Usa ◽  
Novel Coronavirus ◽  
Almost All ◽  
Markov Chain Modelling

Almost all countries around the world are struggling against the novel coronavirus (Covid-19) pandemic. In this paper, a nonlinear Markov chains model is proposed in order to analyse and to understand the behaviour of the Covid-19 pandemic. The data from China was used to build up the presented model. Thereafter, the nonlinear Markov chain model is employed to estimate the daily new Covid-19 cases in some countries including Italy, Spain, France, UK, the USA, Germany, Turkey, and Kuwait. In addition, the correlation between the daily new Covid-19 cases and the daily number of deaths is examined.

scholarly journals Short epidemiological overview of the current situation on COVID-19 pandemic in Southeast European (SEE) countries

2020 ◽  
Vol 14 (05) ◽  
pp. 433-437
Author(s):  
Edmond Puca ◽  
Rok Čivljak ◽  
Jurica Arapović ◽  
Corneliu Popescu ◽  
Iva Christova ◽  
...  
Keyword(s):  
Health Care ◽  
Case Fatality ◽  
Viral Disease ◽  
The Novel ◽  
Outbreak Response ◽  
First Case ◽  
Care Workers ◽  
Novel Coronavirus ◽  
Short Time ◽  
Index Cases

We are living in times where a viral disease has brought normal life in much of the world to a halt. The novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) started in December 2019 in Wuhan, China initially and in a short time crossed the European borders. After mitigating the epidemic in China, Italy became one of the most COVID-19 affected countries worldwide. International travelers are important sources of infectious diseases and a possible source of epidemic. Due to its political, geographic, and cultural similarities, Italy is one of the main economic partners of Southeast European (SEE) countries. Our data show that infection in index cases in all 11 SEE countries was travel-related with Italy being a source country for 8/11 countries. After the first case identifications on February 25, the number of cases in SEE countries is continually rising reaching the total number of 15,612 with 565 fatal cases and overall case fatality ratio (CFR) of 3.6 (median 3.8, range 0.8–5.5) by April 10, 2020. At a time when the COVID-19 pandemic is approaching its peak, apart from the problems with treatment of the disease and care for critically ill patients, there are other equally important problems, such as organization of outbreak response, provision of health care, lack of hospital personnel, disruption of personal protective equipment supply chains and health care workers (HCWs) protection. But what is more important is the heroic behavior of the HCWs who are showing their humanity by disregarding their lives.

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