Abstract P396: Thirty Years of Cardiovascular Mortality in Quebec, is the Decline Slowing in the Younger Population?

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Claudia Blais ◽  
Denis Hamel
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Mortality Rate ◽  
Cardiovascular Mortality ◽  
Age Groups ◽  
Mortality Rates ◽  
Age Group ◽  
Annual Percentage Change ◽  
Specific Mortality ◽  
Adjusted Rate

Background: It has been demonstrated in many countries that cardiovascular mortality has decreased over recent decades and the decline was accelerating for people aged 35 years and older and slowing in the younger population. Coronary heart disease (CHD) and stroke were the major causes responsible of this decline. We hypothesized that this fall and deceleration of the decline has occurred also in Quebec, Canada and looked if other diseases, such as heart failure (HF) and high blood pressure (HBP) presented a similar decline. Methods: Age-adjusted and specific mortality rates were obtained with the Quebec registry of death for each year of 1978–2007 period for all cardiovascular diseases and divided into CHD, stroke, HF and HBP for people aged ≥35 years and for each 10 year-age groups respectively. Joinpoint regressions on these mortality rates were used to estimate the annual percentage change (APC) and to detect points in time at which significant changes in the trends occurred. Several methods of forecasting were compared to predict age-adjusted mortality rates for the next decade (2008–2017). Results: There were 542,712 cardiovascular deaths. All CHD age-adjusted mortality rates for both sexes combined declined with a marked acceleration in 1997 (APC 1978–1997 and 1997–2007 of −3.05 and −5.99 respectively) while stroke presented with a lower decline between years 1988 and 1997 and reaccelerated thereafter (APC 1978–1988: −4.72, 1988–1997: −2.22 and 1997–2007: −5.39). HF presented an increase between years 1978 and 1981 (APC: 6.28) followed by a decline (APC 1981–2007: −3.58). Death due to HBP in the same group showed a deceleration of the decline in 1992 (APC 1978–1992: −7.46 and APC 1992–2007: −1.97). In the group aged 35–44 years, when both sexes were combined, only HF presented an increase in the mortality rate (APC 1978–1992: −7.76 and 1992–2007: 4.97). CHD and stroke presented constant declines for this age group (APC 1978-2007: −5.17 and −4.73, respectively) while HBP had no mortality at all. CHD mortality for all ages is projected to decrease to an adjusted rate of 100 per 100,000 person-year in 2017 (−38% from 2007). Conclusions: Death due to HBP was the only cause responsible of a slowing of the decline in people aged 35 years and older. However, when looking at the younger population, HF is presenting not only a slowing of the decline but, more importantly, an increase in the mortality rate. The forecasting of cardiovascular deaths seems to get a constant decline for the principal cause, CHD.

scholarly journals Transport accident mortality in Chile: trends from 2000 to 2012

2016 ◽  
Vol 21 (12) ◽  
pp. 3711-3718 ◽  
Author(s):  
Tamara Otzen ◽  
Antonio Sanhueza ◽  
Carlos Manterola ◽  
Monica Hetz ◽  
Tamara Melnik
Keyword(s):  
Mortality Rate ◽  
Mortality Rates ◽  
Population Based ◽  
Study Data ◽  
Age Group ◽  
Annual Percentage Change ◽  
Population Based Study ◽  
Southern Zone ◽  
Relative Risks ◽  
Transport Accidents

Abstract The aim of this study is to describe the trends of transport accident mortality in Chile from 2000 to 2012 by year, geographic distribution, gender, age group, and type of accident. Population-based study. Data for transport accident mortality in Chile between 2000 and 2012 were used. The crude and adjusted per region transport accident mortality rates were calculated per 100,000 inhabitants. The annual percentage change (APC) of the rates and relative risks (RR) were calculated. The average transport accident mortality rate (TAMR) in Chile (2000-2012) was 12.2. The rates were greater in men (19.7) than in women (4.8), with a RR of 4.1. The rates were higher in the country's southern zone (15.9), increasing in recent years in the southern zone, with a significant positive APC in the northern and central zones. The Maule region had the highest rate (21.1), although Coquimbo was the region with the most significant APC (2.2%). The highest rate (20.3) was verified in the 25-40 age group. The highest rate (14.3) was recorded in 2008. The most frequent type of accident was pedestrian. In general the APC trends of the rates are increasing significantly. This, added to rapid annual automotive growth, will only exacerbate mortality due to transport accidents.

6129Temporal trends and patterns in cause-specific mortality and hospitalisations after incident heart failure: a longitudinal analysis of 86,000 individuals

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
N Conrad ◽  
A Judge ◽  
D Canoy ◽  
J G Cleland ◽  
J J V McMurray ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiovascular Mortality ◽  
Causes Of Death ◽  
Mortality Rates ◽  
Failure Diagnosis ◽  
The Past ◽  
Specific Mortality ◽  
Heart Failure Diagnosis ◽  
Respiratory Conditions ◽  
Overall Mortality

Abstract Background The past two decades have brought considerable improvements in heart failure care. Clinical trials have demonstrated effectiveness of several different treatments in reducing mortality and hospitalisations, and observational studies have shown that these treatments are increasingly being used in many countries. Little is known about whether these changes have been reflected in patient outcomes in routine clinical settings. Methods We used anonymised electronic health records that link information from primary care, secondary care, and the national death registry to investigate 86,000 individuals with newly diagnosed heart failure between 2002 and 2013 in the UK. We computed all-cause and cause-specific mortality rates and number of hospitalisations in the first year following diagnosis. We used Poisson regression models to calculate category-specific rate ratios and 95% confidence intervals, adjusting for patients' age, sex, region, socioeconomic status and 17 major comorbidities. Findings One year after initial heart failure diagnosis, all-cause mortality rates were high (32%) and did not change significantly over the period of study (adjusted rate ratio (RR) 2013 vs 2002: 0.94 [0.88, 1]). Overall rates masked diverging trends in cause-specific outcomes: a decline in cardiovascular mortality (RR: 0.74 [0.68, 0.81]) was offset by an increase in non-cardiovascular mortality (RR: 1.28 [1.17, 1.39]), largely due to infections and chronic respiratory conditions. Sub-group analyses further showed that overall mortality declined among patients under 80 years of age (RR 2013 vs 2002: 0.79 [0.71, 0.88]), although not in older age groups (RR 2013 vs 2002: 0.97 [0.9, 1.06]). After cardiovascular causes (43%), the major causes of death identified in 2013 were neoplasms (15%), respiratory conditions (12%), and infections (11%). Hospital admissions within a year of heart failure diagnosis were common (1.15 hospitalisations per patient-year at risk), changed little over time (RR: 0.96 [0.92, 0.99]), and were largely (60%) due to non-cardiovascular causes. Interpretation Despite increased use of life-saving interventions, overall mortality and hospitalisations following a new diagnosis of heart failure have changed little over the past decade. Improved prognosis among young and middle-aged patients marks an important achievement and attests of complex barriers to progress in elderly patients. The shift from cardiovascular to non-cardiovascular causes of death suggest that management of associated comorbidities might offer additional opportunities to improve patients' prognosis. Acknowledgement/Funding British Heart Foundation, National Institute for Health Research, UK Research and Innovation.

The Descriptive Epidemiology and Outcomes of Hospitalized Burn Patients in Southern Turkey: Age-specific Mortality Patterns

2020 ◽  
Author(s):  
Kayhan Gurbuz ◽  
Mete Demir
Keyword(s):  
Mortality Rate ◽  
Descriptive Analysis ◽  
Age Groups ◽  
Total Body Surface Area ◽  
Multivariate Regression Analysis ◽  
Inhalation Injury ◽  
Burn Patients ◽  
Age Group ◽  
Specific Mortality ◽  
Fire Flame

Abstract The current descriptive analysis was designed to document the common epidemiologic characteristics and outcomes of burn injuries, and age-specific mortality patterns covering all age groups admitted for treatment to the Burn Center of Adana City Training and Research Hospital (ACTRH). Medical records were retrospectively analyzed. The patients were stratified into two age groups as pediatric and adults, and then into ten sub-age groups. Among the 946 patients of the study population, there were 24 mortalities with a mortality rate of 2.5%. Patients within the age range of 70-79 years had the highest mortality rate of 33.3%; followed by 60-69, 80+, 18-29, 10-17, and <5 sub-age groups, whose mortality rates were, 13.0%, 7.8%, 7.2%, 2.4%, 0.5%, respectively. In terms of multivariate regression analysis of factors predicting mortality among burn patients in all age groups, fire-flame related burns, age ≥18 years, total body surface area burned ≥20 percent (TBSA ≥20%), the existence of inhalation injury, deep partially/full-thickness burns were found to be significant prognostic factors of mortality. The strongest association was seen in TBSA ≥60% segment (p<0.0001), which had 25.9 times more death risk. As expected, a similar trend was detected when the age groups stratified into age groups, and the strongest association was in the 60+ sub-age group (p<0.0001), whose had 5.84 times more likely death; followed by 29-59, 18-29 sub-age groups, with the ORs of 2.12 (95%CI=1.25-3.61), 2.08 (95%CI=1.90-4.05), respectively. Oppose to these findings; the 0-17 sub-age group was not found to have a statistically significant effect in predicting mortality.

scholarly journals Mortality rate of gastric cancer in the population of Belgrade for 1990-2002 period

2005 ◽  
Vol 62 (9) ◽  
pp. 655-660 ◽  
Author(s):  
Sandra Sipetic ◽  
Hristina Vlajinac ◽  
Isidora Ratkov ◽  
Jelena Marinkovic
Keyword(s):  
Gastric Cancer ◽  
Mortality Rate ◽  
Age Groups ◽  
Mortality Rates ◽  
World Population ◽  
Age Group ◽  
The Past ◽  
Mortality Ratio ◽  
Trend Functions ◽  
Annual Decline

Background. Worldwide, gastric cancer is the fourth leading cause of diseases, and the second leading cause of cancer deaths. Aim. To analyze the differences between men and women in mortality rate of gastric cancer in Belgrade from 1990?2002. Methods. Mortality rates standardized directly to the ?World population?, and regression analysis were used. Results. In Belgrade population, 29.2% out the total number of deaths attributable to cancer were caused by gastric cancer. Gastric cancer was the second most common cause of death among digestive tract cancers. In women, in the period between 1990 and 1993, an average annual decline of mortality was 9.0% (95% confidence interval (CI) = 5.9?13.1), and between 1994 and 2002, an average annual increase was 10.3% (CI = 8.4?12.6). Mortality rate series of gastric cancer in men did not fit any of the usual trend functions. The male/female gastric cancer mortality ratio was 1.7 : 1. Mortality rates for gastric cancer rose with age in both sexes and they were highest in the age group of 70 and more years. From 1990?2002, in both sexes aged 70 years and more, mortality from gastric cancer rose by 67.2% (CI = 58.0?76.4) in men and by 69.6% (CI = 60.6?78.6) in women. During the same period, the death rates in men decreased by 75.9 % (CI = 67.5?84.4) in the age group of 30?39 years, and by 48.1% (CI = 38.4?57.9) in women aged 50?59 years. In both sexes mortality rate series of all other age groups did not fit any of the usual trend functions. Conclusions. The increase in mortality rate of gastric in women over the past few years, showed the necessity of instituting primary and secondary preventive measures.

scholarly journals Coronary heart disease incidence still decreased between 2006 and 2014 in France, except in young age groups: Results from the French MONICA registries

2020 ◽  
Vol 27 (11) ◽  
pp. 1178-1186 ◽  
Author(s):  
Aline Meirhaeghe ◽  
Michèle Montaye ◽  
Katia Biasch ◽  
Samantha Huo Yung Kai ◽  
Marie Moitry ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Age Groups ◽  
Coronary Event ◽  
Mortality Rates ◽  
Percentage Change ◽  
Age Group ◽  
Acute Coronary Event ◽  
Annual Percentage Change ◽  
Men And Women

Background Over the past few decades decreases in coronary heart disease morbidity and mortality rates have been observed throughout the western world. We sought to determine whether the acute coronary event rates had decreased between 2006 and 2014 among French adults, and whether there were sex and age-specific differences. Methods We examined the French MONICA population-based registries monitoring the Lille urban area in northern France, the Bas-Rhin county in north-eastern France and the Haute Garonne county in south-western France. All acute coronary events among men and women aged 35–74 were collected. Results Over the study period, the age-standardised attack rates decreased in both men (annual percentage change −1.5%, P = 0.0006) and women (annual percentage change −2.1%, P = 0.002). Also, the age-standardised incidence rates decreased in both men (annual percentage change −0.9%, P = 0.03) and women (annual percentage change −1.8%, P = 0.002) due to decreases in the 65–74 year age group. In men, age-standardised mortality rates decreased by 3.5% per year ( P = 0.0004), especially in the 55–64 and 65–74 year age groups. In women, these rates decreased by 4.3% per year ( P = 0.0009), particularly in the 35–44 and 65–74 year age groups. We also observed significant decreases in case fatality among both men (annual percentage change −1.7%, P < 0.0001) and women (annual percentage change −1.9%, P = 0.009). Conclusions Downward trends in acute coronary event attack, incidence and mortality rates were observed between 2006 and 2014 in men and women. This effect was age dependent and was primarily due to decreases in the 65–74 year age group. There were no substantial declines in the younger age groups except for mortality in young women. Prevention measures still need to be strengthened, particularly in young adults.

scholarly journals The trend in the mortality rate and life expectancy of the employable age population in Kuzbass (2011–2018)

2021 ◽  
Vol 65 (3) ◽  
pp. 198-207
Author(s):  
Olga I. Baran ◽  
Natalya M. Zhilina ◽  
Valeriy A. Ryabov
Keyword(s):  
Mortality Rate ◽  
Life Expectancy ◽  
Rural Areas ◽  
Health Care Financing ◽  
Age Groups ◽  
Mortality Rates ◽  
Living Environment ◽  
Specific Mortality ◽  
Urban Settlements

The mortality rate and life expectancy are the most important characteristics of public health, depending on the country’s socio-economic development, living conditions, and the quality of the living environment. At the state level, excess mortality at the working-age is recognized as an important reason for the low life expectancy of Russians. The objective of the study is to analyze the trend in the mortality rate and life expectancy of the employable age population of the Kemerovo region during 2011-2018. Material and methods. To estimate the mortality rate, the general and age-specific mortality rates, mortality rates by significant classes and individual causes of death were used. The life expectancy of the employable age population was calculated using temporary mortality tables based on age-specific mortality rates. A graphic analysis of the dynamics of age-specific mortality rates and the life expectancy in men and women of employable age in urban settlements, rural areas and the entire population of the Kemerovo region was carried out over five-year age intervals for 2011-2018. Statistical data obtained on the website of Rosstat. Results. In 2018, in the Kemerovo region, the mortality rate of 40-44 year men in urban settlements, 35-44 years old in rural areas, and women 35-44 years old in urban settlements and rural areas exceeded the level of 2011, which negatively affected the dynamics of life expectancy. In rural areas, due to these age groups, the life expectancy in men decreased by 0.57, women - by 0.41 years. Losses in urban settlements were minor. Conclusion. When developing regional socio-demographic programs, it is necessary to consider the identified features of mortality of the employable age population. An increase in life expectancy is impossible without overcoming the socio-economic crisis, improving health care financing, and increasing the availability and quality of medical care. A person should be interested in improving his health, saving his life. It is necessary to raise the level of culture, education, change the mentality.

scholarly journals Temporal trend in adolescent mortality from aggression in Brazil, 2000 to 2017

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
V O M Pereira ◽  
E C Aquino ◽  
R B Corassa ◽  
M D M Mascarenhas ◽  
W M Ramalho ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Temporal Trend ◽  
Age Groups ◽  
Population Group ◽  
Social Situation ◽  
Mortality Rates ◽  
Percentage Change ◽  
Ecological Design ◽  
Annual Percentage Change ◽  
Upward Trend

Abstract Background Mortality from aggression in adolescents reflects one of the symptoms of the Brazilian social situation, which makes this population group vulnerable, exposing them to situations that determine their death in an early and violent way. This work contributes to the analysis of the temporal trend of adolescent mortality due to aggression throughout Brazil from 2000 to 2017. Methods A ecological design time series was carried out on the mortality rate of adolescents due to aggression in Brazil, from 2000 to 2017. Data from the Mortality Information System (SIM) of the Ministry of Health of Brazil was used. Mortality rates were analyzed according to sex and age groups (10-14 and 15-19 years). The joinpoint regression method was used to calculate the annual trend in mortality rates. Results The mortality rate among female adolescents aged 10 to 14 years decreased from 1.81 to 1.74 deaths/100 thousand inhab., and in the group aged 15 to 19, increased from 6.64 to 7.87 deaths/100.000 inhab., from 2000 to 2017. The Average Annual Percentage Change (AAPC) of the rates showed a steady trend of mortality in the groups from 10 to 14 years (AAPC = -0.4; 95% CI -1.4-0.7) and 15 to 19 years (AAPC = 0.7; 95% CI -2.3-3.9). In males, the rate for the 10 to 14-year-old group increased from 4.56 to 6.64 deaths/100.000 inhab., and in the 15 to 19 year old group, increased from 73.06 to 122.78 deaths/100.000 inhab., from 2000 to 2017. The AAPC showed an upward trend in the groups between 10 and 14 years old (AAPC = 2.3; 95% CI % 0.2-4.4) and 15 to 19 years (AAPC = 2.8; 95% CI 2.1-3.5). In the 15 to 19-year-old group, the upward trend of the period between 2009 and 2017 stood out [Annual Percentage Change (APC) = 5.1; 95% CI 4.0-6.3)]. Conclusions This analysis can contribute with subsidies for the improvement of public policies and intersectoral actions that act on the vulnerabilities to which adolescents are exposed and that reduce the mortality rates due to aggressions. Key messages Mortality from aggression in adolescents aged 15-19 showed, in the female sex, an increase from 6.64 to 7.87 deaths/100.000 inhab., and in males, an increase from 73.06 to 122.78 deaths/100.000 inhab. The upward trend in the mortality rate in male adolescents aged 15 to 19 was highlighted in the period from 2009 to 2017 [Annual Percentage Variation (APC) = 5.1; 95% CI 4.0–6.3).

Outcome in an Urban Pediatric Trauma System with Unified Prehospital Emergency Medical Services Care

1995 ◽  
Vol 10 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Michael J. VanRooyen ◽  
Edward P. Sloan ◽  
John A. Barrett ◽  
Robert F. Smith ◽  
Hernan M. Reyes
Keyword(s):  
Head Injury ◽  
Mortality Rate ◽  
Trauma Center ◽  
Pediatric Trauma ◽  
Trauma System ◽  
Age Groups ◽  
Mortality Rates ◽  
Trauma Centers ◽  
Field Triage ◽  
Pediatric Trauma Center

AbstractHypothesis:Pediatric mortality is predicted by age, presence of head trauma, head trauma with a low Glasgow Coma Scale (GCS) score, a low Pediatric Trauma Score (PTS), and transport directly to a pediatric trauma center.Population:Studied were 1,429 patients younger than 16 years old admitted to or declared dead on arrival (DOA) in a pediatric trauma center from January through October, 1988. The trauma system, which served 3-million persons, included six pediatric trauma centers.Methods:Data were obtained by a retrospective review of summary statistics provided to the Chicago Department of Health by the pediatric trauma centers.Results:Overall mortality was 4.8% (68 of 1429); 32 of the patients who died (47.1%) were DOA. The in-hospital mortality rate was 2.6%. Head injury was the principal diagnosis in 46.2% of admissions and was a factor in 72.2% of hospital deaths. The mortality rate was 20.3% in children with a GCS≤10 and 0.4% when the GCS was >10 (odds ratio [OR] = 67.0, 95% CI = 15.0–417.4). When the PTS was ≤ 5, mortality was 25.6%; with a PTS > 5, the mortality was 0.2% (OR = 420.7, 95% CI = 99.3–2,520). Although transfers to a pediatric trauma center accounted for 73.6% of admissions, direct field triage to a pediatric trauma center was associated with a 3.2 times greater mortality risk (95% CI = 1.58–6.59). Mortality rates were equal for all age groups. Pediatric trauma center volume did not influence mortality rates.Conclusions:Head injury and death occur in all age groups, suggesting the need for broad prevention strategies. Specific GCS and PTS values that predict mortality can be used in emergency medical services (EMS) triage protocols. Although the high proportion of transfers mandates systemwide transfer protocols, the lower mortality in these patients suggests appropriate EMS field triage. These factors should be considered as states develop pediatric trauma systems.

Abstract P261: Intensive Systolic Blood Pressure Lowering Will Prevent Over 100,000 Deaths Annually

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Holly Kramer ◽  
Adam Bress ◽  
Srinivasan Beddhu ◽  
Paul Muntner ◽  
Richard S Cooper
Keyword(s):  
Blood Pressure ◽  
Mortality Rate ◽  
Systolic Blood Pressure ◽  
Mortality Rates ◽  
Mortality Data ◽  
Blood Pressure Lowering ◽  
Cvd Risk ◽  
Pressure Lowering ◽  
Annual Mortality ◽  
The U.S

Background: The Systolic Blood Pressure Intervention Trial (SPRINT) trial randomized 9,361 adults aged ≥50 years at high cardiovascular disease (CVD) risk without diabetes or stroke to intensive systolic blood pressure (SBP) lowering (≤120 mmHg) or standard SBP lowering (≤140 mmHg). After a median follow up of 3.26 years, all-cause mortality was 27% (95% CI 40%, 10%) lower with intensive SBP lowering. We estimated the potential number of prevented deaths with intensive SBP lowering in the U.S. population meeting SPRINT criteria. Methods: SPRINT eligibility criteria were applied to the National Health and Nutrition Examination Survey 1999-2006, a representative survey of the U.S. population, linked with the mortality data through December 2011. Eligibility included (1) age ≥50 years with (2) SBP 130-180 mmHg depending on number of antihypertensive classes being taken, and (3) presence of ≥1 CVD risk conditions (history of coronary heart disease, estimated glomerular filtration rate (eGFR) 20 to 59 ml/min/1.73 m 2 , 10-year Framingham risk score ≥15%, or age ≥75 years). Adults with diabetes, stroke history, >1 g/day proteinuria, heart failure, on dialysis, or eGFR<20 ml/min/1.73m 2 were excluded. Annual mortality rates for adults meeting SPRINT criteria were calculated using Kaplan-Meier methods and the expected reduction in mortality rates with intensive SBP lowering in SPRINT was used to determine the number of potential deaths prevented. Analyses accounted for the complex survey design. Results: An estimated 18.1 million U.S. adults met SPRINT criteria with 7.4 million taking blood pressure lowering medications. The mean age was 68.6 years and 83.2% and 7.4% were non-Hispanic white and non-Hispanic black, respectively. The annual mortality rate was 2.2% (95% CI 1.9%, 2.5%) and intensive SBP lowering was projected to prevent 107,453 deaths per year (95% CI 45,374 to 139,490). Among adults with SBP ≥145 mmHg, the annual mortality rate was 2.5% (95% CI 2.1%, 3.0%) and intensive SBP lowering was projected to prevent 60,908 deaths per year (95% CI 26, 455 to 76, 792). Conclusions: We project intensive SBP lowering could prevent over 100,000 deaths per year of intensive treatment.

scholarly journals Treatment of cyanotic heart diseases in children

2004 ◽  
Vol 132 (suppl. 1) ◽  
pp. 9-13
Author(s):  
Ida Jovanovic ◽  
Vojislav Parezanovic ◽  
Slobodan Ilic ◽  
Djordje Hercog ◽  
Milan Vucicevic ◽  
...  
Keyword(s):  
Heart Disease ◽  
Mortality Rate ◽  
Surgical Procedures ◽  
Heart Surgery ◽  
Heart Diseases ◽  
Arterial Switch Operation ◽  
Open Heart Surgery ◽  
Age Groups ◽  
Mortality Rates ◽  
Cyanotic Heart Disease

Cyanotic heart diseases are relatively rare, but they are severe and heterogeneous congenital heart diseases, which require complex surgery. Development of different advanced surgical procedures, such as arterial switch operation (ASO), Fontan and its modifications, Norwood etc. operations, as well as better perioperative care significantly improved survival rate and quality of life of these children. The study group included 308 children treated for cyanotic heart disease in Yugoslavia, in the period January 2000 to July 2004. Some of them (239, 77.6%) were treated at the University Children?s Hospital in Belgrade, and others (69, 22.4%) in different institutions abroad. The age of the operated patients varied between 1 day and 19 years (median 12 months). The patients (pts) were divided into four groups, according to the disease and type of the operation. In the whole group of 308 patients treated due to cyanotic heart disease, there were 232 (75.3%) cases with open heart surgery and 76 (24.7%) with closed procedures. The mortality rate was significantly different between disease/operation groups, and age groups. Average mortality rates differed from 11.8% for palliative procedures to 12.5% for complete corrections. Mortality rate and achieved surgical results in treatment of chil?dren with cyanotic heart diseases were significantly worse than those published by leading cardiac surgery centers in the world. However, there is a clear tendency in introducing new surgical procedures, lowering the age at which the operation is done and decreasing the mortality rates.

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