Abstract 153: Automated Angiographic Assessment Of Coronary Artery Vasomotion In Kawasaki Disease Patients

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Mitchel Benovoy ◽  
Farida Cheriet ◽  
Roch L Maurice ◽  
Nagib Dahdah
Keyword(s):  
Health Assessment ◽  
Assessment System ◽  
Vascular Health ◽  
Pressure Gradients ◽  
Intracoronary Imaging ◽  
Temporal Tracking ◽  
Vascular Physiology ◽  
The Mean ◽  
Spatio Temporal ◽  
Stiffness Characteristics

Background: Mechanical properties of coronary arteries (CA) hold clues to vascular health and viability. Traditionally assessed with intracoronary imaging, we present an angiography-based system to assess CA vasomotion using automatic vessel segmentation and spatio-temporal tracking. Elastic moduli computed from dynamic CA calibers are compared between non-KD patients (CTL), KD patients with no CA aneurysms (KDAN-), and those with aneurysms (KDAN+). Methods: Proximal CA angiograms are automatically segmented and tracked over a cardiac cycle. CA centerline is extracted and the mean caliber is computed from diameters along its length. The resulting caliber variation reflects the CA vasomotion (Figure 1a). We then calculated the Vasomotion Standard Deviation (VSD) and CA recoil with the mean constriction velocity (MCV). Finally, Elastic Pressure moduli were computed using trans-myocardium pressure gradients. Results: We analyzed 51 left CA segments from 23 patients (5 CTL, 5 KDAN-, 13 KDAN+). Data are mean ± SD normalized pixels (npx). VSD was significantly reduced ( p <0.01) in KDAN+ (0.25±0.05) and KDAN- (0.27±0.04) vs CTL (0.38±0.07 npx). Coronary recoil was significantly reduced (p<0.05) in KDAN+ vs CTL, with MCV 3.50±0.67 vs 4.59±1.94 npx/sec. Pressure-dependent stiffness characteristics were equally atypical (Figure 1b). Conclusion: The proposed angiography-based stiffness assessment system shows abnormal CA vascular physiology in our cohort of KD patients. These results concur with previous invasive studies. The potential usability of this system for vascular health assessment could be applied to previously recorded CA angiograms for risk stratification.

The Use of the International Caries Detection and Assessment System (ICDAS) in a National Health Service General Dental Practice as Part of an Oral Health Assessment

2010 ◽  
Vol os17 (4) ◽  
pp. 153-160 ◽  
Author(s):  
Charles Ormond ◽  
Gail Douglas ◽  
Nigel Pitts
Keyword(s):  
Oral Health ◽  
National Health Service ◽  
Health Service ◽  
Health Assessment ◽  
Assessment System ◽  
Caries Detection ◽  
Dental Practice ◽  
General Dental Practice ◽  
The Mean ◽  
Mean Time

Introduction The Scottish Dental Clinical Effectiveness Programme (SDCEP) is developing guidance for oral health assessment and review that is intended for use in National Health Service (NHS) general dental practice. One section of this guidance is assessment of the teeth, including their caries status. The detailed caries assessment method identified by the guidance group is the International Caries Detection and Assessment System (ICDAS). Aim The aim of this study was to investigate the implications of using the ICDAS in an NHS general practice and, in particular, the time taken to use the system. Method After online and in-practice training and calibration, 50 adult and 50 child patients were randomly allocated for assessment using the ICDAS detection codes. The ICDAS protocol states that the teeth should be clean and dry. For this study, all patients had their teeth brushed by the dentist before the assessment and the results were recorded on draft ICDAS clinical pro forma sheets. The time taken for the assessment was assessed with a stopwatch and recorded in a spreadsheet program. Results The results showed that the mean time for the assessment of an adult was 3.80 minutes, or 4.99 minutes if the time for pre-examination cleaning and drying was included. For a child, the mean time was 2.53 minutes, or 3.99 minutes if pre-examination brushing time was included. Conclusions These results indicate that with training and experience, it is possible to carry out an ICDAS assessment in a time that is practical in general dental practice.

scholarly journals AB0189 ASSESSMENT OF POWER DOPPLER SYNOVITIS IN RHEUMATOID ARTHRITIS PATIENTS WITH CLINICAL REMISSION

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1394.2-1394
Author(s):  
R. Fakhfakh ◽  
N. El Amri ◽  
K. Baccouche ◽  
H. Zeglaoui ◽  
E. Bouajina
Keyword(s):  
Rheumatoid Arthritis ◽  
Functional Capacity ◽  
Clinical Remission ◽  
Power Doppler ◽  
Health Assessment ◽  
Disease Flare ◽  
Synovial Hypertrophy ◽  
The Mean ◽  
Grade 3 ◽  
Subclinical Synovitis

Background:Ultrasound-detected synovitis, mainly synovial Doppler signal, has shown predictive value in relation to radiographic damage progression and disease flare or relapse in rheumatoid arthritis (RA) patients with clinical remission.Objectives:The aim of the study was to analyze the correlation between power Doppler scores and clinical/laboratory and radiographic data in clinical remission RA patients.Methods:Cross-sectional study including patients with RA in clinical remission defined by: DAS28ESR ≤ 2.6, without disease flare or changes in therapy in the previous 6 months. Each patient underwent ultrasound: B-mode and PD assessments of 36 joints and 20 tendons in the Rheumatology Department over a period of 6 month. Synovitis and tenosynovitis were defined and scored according to the Outcome Measures in Rheumatology Clinical Trials (OMERACT). Radiological measurements included the modified Sharp/van der Heijde method (SHS). Functional capacity was assessed by the Health Assessment Questionnaire (HAQ).Results:Thirty two patients were enrolled, the mean age was 53.7±13.4 and 75% were female. The mean disease duration was 15 years ± 8.8. Subclinical synovitis were the most frequent in wrist (56.3%), 2ndmetacarpophalangeal joints (28.1%) and 2ndmetatarsophalangeal joints (29%). The mean subclinical synovitis/ tenosynovitis numbers was 4±3.1 per patient. Synovial hypertrophy and B mode tenosynovitis were detected in 93.8%: 71.3% had a grade = 2 and 9.8% had a grade= 3. Total B mode score was correlated only with the SHS score in the feet (r: 0.4, p: 0.03). PD signal was detected in 62.5% of patients: 37.5% had a grade =2 and 9.4% had a grade= 3. Total PD score was correlated with DAS28 (r:0.42, p:0.02), the SHS score in the hands (r:0.39, p:0.03) and in the feet (r:0.5, p:0.007), synovial hypertrophy (r:0.6, p:0.0001) and HAQ (r:0.32, p:0.06). No correlation was found with CDAI, SDAI, swollen joint counts, tender joint counts, patient global health assessment, erythrocyte sedimentation rate, C-reactive protein, rheumatoid factor and anti-cyclic citrullinated peptide, biologic treatment.Conclusion:Synovial hypertrophy and PD signal were frequent in RA remission. PD signal was associated with RA activity, radiologic damage and functional capacity.References:[1]Yan Geng & Jingjing Han & Xuerong Deng and al. Presence of power Doppler synovitis in rheumatoid arthritis patients with synthetic and/or biological disease-modifying anti-rheumatic drug-induced clinical remission: experience from a Chinese cohort. Clinical Rheumatology 2014. DOI 10.1007/s10067-014-2634-yDisclosure of Interests:None declared

Non-invasive determination of the systolic peak-to-peak gradient in children with aortic stenosis: validation of a mathematical model

2000 ◽  
Vol 10 (2) ◽  
pp. 115-119 ◽  
Author(s):  
Valter C. Lima ◽  
Evan Zahn ◽  
Christine Houde ◽  
Jeffrey Smallhorn ◽  
Robert M. Freedom ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Pulse Pressure ◽  
Linear Regression Analysis ◽  
Systolic Pressure ◽  
Pressure Gradients ◽  
Non Invasive ◽  
The Mean ◽  
Congenital Aortic Valvar Stenosis ◽  
Peak Gradient

AbstractDoppler derived systolic pressure gradients have become widely applied as noninvasively obtained estimates of the severity of aortic valvar stenosis. There is little correlation, however, between the Doppler derived peak instantaneous gradient and the peak-to-peak gradient obtained at catheterisation, the latter being the most applied variable to determine severity in children. The purpose of this study was to validate a mathematical model based on data from catheterisation which estimates the peak-to-peak gradient from variables which can be obtained by noninvasive means (Doppler derived mean gradient and pulse pressure), according to the formula: peak-to-peak systolic gradient=6.02+1.49*(mean gradient)−0.44*(pulse pressure). Simultaneous cardiac catheterization and Doppler studies were performed on 10 patients with congenital aortic valvar stenosis. Correlations between the gradients measured at catheter measured, and those derived by Doppler, were performed using linear regression analysis. The mean gradients correlated well (y=0.67 × + 11.11, r=0.87, SEE=6 mm Hg, p=0.001). The gradients predicted by the formula also correlated well with the peak-to-peak gradients measured at catheter (y=0.66 × + 14.44, r=0.84, SEE=9 mm Hg, p=O.002). The data support the application of the model, allowing noninvasive prediction of the peak-to-peak gradient across the aortic valvar stenosis.

Protein osmotic pressure gradients and microvascular reflection coefficients

1997 ◽  
Vol 273 (2) ◽  
pp. H997-H1002 ◽  
Author(s):  
R. E. Drake ◽  
S. Dhother ◽  
R. A. Teague ◽  
J. C. Gabel
Keyword(s):  
Reflection Coefficient ◽  
Pressure Gradient ◽  
Osmotic Pressure ◽  
Reflection Coefficients ◽  
Pressure Gradients ◽  
Fluid Filtration ◽  
The Mean ◽  
Osmotic Reflection Coefficient ◽  
New Equation ◽  
Osmotic Pressure Gradient

Microvascular membranes are heteroporous, so the mean osmotic reflection coefficient for a microvascular membrane (sigma d) is a function of the reflection coefficient for each pore. Investigators have derived equations for sigma d based on the assumption that the protein osmotic pressure gradient across the membrane (delta II) does not vary from pore to pore. However, for most microvascular membranes, delta II probably does vary from pore to pore. In this study, we derived a new equation for sigma d. According to our equation, pore-to-pore differences in delta II increase the effect of small pores and decrease the effect of large pores on the overall membrane osmotic reflection coefficient. Thus sigma d for a heteroporous membrane may be much higher than previously derived equations indicate. Furthermore, pore-to-pore delta II differences increase the effect of plasma protein osmotic pressure to oppose microvascular fluid filtration.

scholarly journals Collaborative Case-Based Reasoning for Knowledge Discovery of Elders Health Assessment System

2014 ◽  
Vol 8 (1) ◽  
pp. 68-74 ◽  
Author(s):  
Ping Hu ◽  
Dong-xiao Gu ◽  
Yu Zhu
Keyword(s):  
Single Case ◽  
Health Assessment ◽  
Assessment System ◽  
Gray Relational Analysis ◽  
Retrieval Algorithm ◽  
Case Based Reasoning ◽  
Knowledge Reuse ◽  
Case Retrieval ◽  
Case Library ◽  
Case Representation

The existing Elders Health Assessment (EHA) system based on single-case-library reasoning has low intelligence level, poor coordination, and limited capabilities of assessment decision support. To effectively support knowledge reuse of EHA system, this paper proposes collaborative case reasoning and applies it to the whole knowledge reuse process of EHA system. It proposes a multi-case library reasoning application framework of EHA knowledge reuse system, and studies key techniques such as case representation, case retrieval algorithm, case optimization and correction, and reuse etc.. In the aspect of case representation, XML-based multi-case representation for case organization and storage is applied to facilitate case retrieval and management. In the aspect of retrieval method, Knowledge-Guided Approach with Nearest-Neighbor is proposed. Given the complexity of EHA, Gray Relational Analysis with weighted Euclidean Distance is used to measure the similarity so as to improve case retrieval accuracy.

scholarly journals Tropospheric temperature variation over India and links with the Indian summer monsoon : 1971-2000

MAUSAM ◽  
2022 ◽  
Vol 53 (3) ◽  
pp. 289-308
Author(s):  
D. R. KOTHAWALE ◽  
K. RUPA KUMAR
Keyword(s):  
Summer Monsoon ◽  
Southern Oscillation ◽  
Monsoon Season ◽  
Temporal Variations ◽  
Mean Annual Temperature ◽  
Tropospheric Temperature ◽  
Temperature Variations ◽  
Annual Cycles ◽  
The Mean ◽  
Spatio Temporal

In the context of the ever increasing interest in the regional aspects of global warming, understanding the spatio-temporal variations of tropospheric temperature over India is of great importance. The present study, based on the data from 19 well distributed radiosonde stations for the period 1971-2000, examines the seasonal and annual mean temperature variations at the surface and five selected upper levels, viz., 850, 700, 500, 200 and 150 hPa. An attempt has also been made to bring out the association between tropospheric temperature variations over India and the summer monsoon variability, including the role of its major teleconnection parameter, the El Niño/Southern Oscillation (ENSO).   Seasonal and annual mean all-India temperature series are analyzed for surface and five tropospheric levels.  The mean annual cycles of temperature at different tropospheric levels indicate that the pre-monsoon season is slightly warmer than the monsoon season at the surface, 850 hPa and 150 hPa levels, while it is relatively cooler at all intermediate levels.  The mean annual temperature shows a warming of 0.18° C and 0.3° C per 10 years at the surface and 850 hPa, respectively.   Tropospheric temperature anomaly composites of excess (deficient) monsoon rainfall years show pronounced positive (negative) anomalies during the month of May, at all the levels.  The pre-monsoon pressure of Darwin has significant positive correlation with the monsoon temperature at the surface and 850 hPa.

scholarly journals Comparison of Land Surface Temperature During and Before the Emergence of Covid-19 using Modis Imagery in Wuhan City, China

2020 ◽  
Vol 34 (1) ◽  
Author(s):  
Hamim Zaky Hadibasyir ◽  
Seftiawan Samsu Rijal ◽  
Dewi Ratna Sari
Keyword(s):  
Surface Temperature ◽  
Land Surface Temperature ◽  
Land Surface ◽  
Anthropogenic Activities ◽  
Temporal Analysis ◽  
The Past ◽  
Modis Imagery ◽  
Rapid Transmission ◽  
The Mean ◽  
Spatio Temporal

Coronavirus disease (COVID-19) was firstly identified in Wuhan, China. By 23rd January 2020, China’s Government made a decision to execute lockdown policy in Wuhan due to the rapid transmission of COVID-19. It is essential to investigate the land surface temperature (LST) dynamics due to changes in level of anthropogenic activities. Therefore, this study aims (1) to investigate mean LST differences between during, i.e., December 2019 to early March 2020, and before the emergence of COVID-19 in Wuhan; (2) to conduct spatio-temporal analysis of mean LST with regards to lockdown policy; and (3) to examine mean LST differences for each land cover type. MODIS data consist of MOD11A2 and MCD12Q1 were employed. The results showed that during the emergence of COVID-19 with lockdown policy applied, the mean LST was lower than the mean LST of the past three years on the same dates. Whereas, during the emergence of COVID-19 without lockdown policy applied, the mean LST was relatively higher than the mean LST of the past three years. In addition, the mean LST of built-up areas experienced the most significant differences between during the emergence of COVID-19 with lockdown policy applied in comparison to the average of the past three years.

scholarly journals Time-to-Boundary Function to Study the Development of Upright Stance Control in Children

2017 ◽  
Vol 11 (1) ◽  
pp. 49-58
Author(s):  
Carmen D'Anna ◽  
Maurizio Schmid ◽  
Andrea Scorza ◽  
Salvatore A. Sciuto ◽  
Luisa Lopez ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Postural Control ◽  
Postural Stability ◽  
Age Groups ◽  
Boundary Function ◽  
Mean Value ◽  
Upright Stance ◽  
Eyes Closed ◽  
The Mean ◽  
Spatio Temporal

Background: The development of postural control across the primary school time horizon is a complex process, which entails biomechanics modifications, the maturation of cognitive ability and sensorimotor organization, and the emergence of anticipatory behaviour. Postural stability in upright stance has been thus object of a multiplicity of studies to better characterize postural control in this age span, with a variety of methodological approaches. The analysis of the Time-to-Boundary function (TtB), which specifies the spatiotemporal proximity of the Centre of Pressure (CoP) to the stability boundaries in the regulation of posture in upright stance, is among the techniques used to better characterize postural stability in adults, but, as of now, it has not yet been introduced in developmental studies. The aim of this study was thus to apply this technique to evaluate the development of postural control in a sample population of primary school children. Methods: In this cross-sectional study, upright stance trials under eyes open and eyes closed were administered to 107 healthy children, divided into three age groups (41 for Seven Years' Group, Y7; 38 for Nine Years' Group, Y9; 28 for Eleven Years' Group, Y11). CoP data were recorded to calculate the Time-to-Boundary function (TtB), from which four spatio-temporal parameters were extracted: the mean value and the standard deviation of TtB minima (Mmin, Stdmin), and the mean value and the standard deviation of the temporal distance between two successive minima (Mdist, Stddist). Results: With eyes closed, Mmin and Stdmin significantly decreased and Mdist and Stddist increased for the Y7 group, at Y9 Mmin significantly decreased and Stddist increased, while no effect of vision resulted for Y11. Regarding age groups, Mmin was significantly higher for Y9 than Y7, and Stdmin for Y9 was higher than both Y7 and Y11; Mdist and Stddist resulted higher for Y11 than for Y9. Conclusion: From the combined results from the spatio-temporal TtB parameters, it is suggested that, at 9 years, children look more efficient in terms of exploring their limits of stability than at 7, and at 11 the observed TtB behaviour hints at the possibility that, at that age, they have almost completed the maturation of postural control in upright stance, also in terms of integration of the spatio-temporal information.

scholarly journals Characterisation of pH variations along the Ba River in Fiji utilising the GEF R2R framework during the 2019 sugarcane season

2021 ◽  
Vol 193 (12) ◽  
Author(s):  
Nicholas Metherall ◽  
Elisabeth Holland ◽  
Sara Beavis ◽  
Adi Mere Dralolo Vinaka
Keyword(s):  
Water Quality ◽  
Small Island ◽  
Sugar Mill ◽  
Rapid Sampling ◽  
Potential Source ◽  
Data Loggers ◽  
The Mean ◽  
Spatio Temporal ◽  
Measured Water ◽  
Ph Variations

AbstractWithin Pacific Small Island Developing States (Pacific SIDS), the ridge-to-reef (R2R) approach has emerged as a framework for monitoring river connectivity between terrestrial and marine ecosystems. The study measured water quality, including pH, over 88.40 km of the Ba River in Fiji. The sampling design focused on measuring spatio-temporal variability in pH throughout the sugarcane season with three rapid sampling periods (RSP1, 2 & 3) along the Ba River, together with continuous measurement of temperature and pH using stationary data loggers at two locations upstream and downstream of the sugar mill. Spatial variability in pH and water quality was characterised before (RSP1 and RSP2) and during (RSP3) the sugarcane season. Mean pH measured before the sugarcane crushing season for RSP1 and RSP2 were 8.16 (± 0.49) and 8.20 (± 0.61) respectively. During the sugarcane crushing season (RSP3), mean pH declined by 3.06 units to 6.94 within 42 m downstream of the sugar mill (P ≤ 0.001). The 3.06 unit decline in pH for RSP3 exceeded both the mean diurnal variation in pH of 0.39 and mean seasonal variation in pH of 2.01. This decline in pH could be a potential source of acidification to downstream coastal ecosystems with implications for coral reefs, biodiversity and fishery livelihoods.

scholarly journals Spatio-temporal variations of land surface temperature and precipitation due to climate change in the Jhelum river basin, India

MAUSAM ◽  
2021 ◽  
Vol 71 (4) ◽  
pp. 661-674
Author(s):  
HIMAYOUN DAR ◽  
ROSHNI THENDIYATH ◽  
MOHSIN FAROOQ
Keyword(s):  
Neural Network ◽  
Artificial Neural Network ◽  
21St Century ◽  
Temporal Variations ◽  
Average Increase ◽  
Temperature And Precipitation ◽  
Rcp 8.5 ◽  
The Mean ◽  
Spatio Temporal ◽  
Precipitation And Temperature

The present study investigated the spatio-temporal variations of precipitation and temperature for the projected period (2011-2100) in the Jhelum basin, India. The precipitation and temperature variables are projected under RCP 8.5 scenario using statistical down scaling techniques such as Artificial Neural Network (ANN) and Wavelet Artificial Neural Network (WANN) models. Firstly, the screened predictors were downscaled to predictand using ANN and WANN models for all the study stations. On the basis of the performance criteria, the WANN model is selected as an efficient model for downscaling of precipitation and temperature. The future screened predictor data pertaining to RCP 8.5 of CanESM2 model were downscaled to monthly temperature and precipitation for future periods (2011-2100) using WANN models. The investigation of the future projections revealed an average increase of 17-25% in the mean annual precipitation and 20-25% average increase in the monthly mean precipitation for all the selected stations towards the end of 21st century. The monthly mean temperature also showed an increase of 2-3 °C for all the study stations towards the end of 21st century. The mean seasonal temperature of the projected period is found to be increasing for all the four seasons in most parts of the basin.

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