Abstract MP17: Relationship of Accelerometer-assessed Physical Activity and Sedentary Behavior with Predicted CVD Risk in Older Women: Results From the Objective Physical Activity and Cardiovascular Health (OPACH) Study

Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Michael J LaMonte ◽  
Eileen Rillamus-Sun ◽  
Kelly R. Evenson ◽  
I-Min Lee ◽  
Dori E. Rosenberg ◽  
...  

Background: Use of accelerometers to objectively measure physical activity (PA) and sedentary behavior (SB) in epidemiologic studies may improve understanding of associations with CVD, particularly in older adults. This cross-sectional study examined associations between accelerometer measures of PA and SB with cardiovascular health in 4870 race-ethnically diverse postmenopausal women, ages 63 to 99 years (mean 78.9) enrolled in OPACH, an ancillary study of the Women’s Health Initiative program. Methods: Vector magnitude counts per 15-sec epoch from hip worn triaxial accelerometers (minimum of 4 days with ≥10 hours/day wear time) were used to define time spent in SB (0-18 counts/15 sec), low light intensity (19-225), high light intensity (226-518), and moderate-to-vigorous intensity PA (MVPA; ≥519) based on count cutpoints determined from a laboratory calibration study among women of similar age. Predicted 10-year risk of CVD was computed using the Reynolds risk score (RRS), for which higher values reflect higher predicted CVD risk. Relationships between SB, PA and RRS were examined using generalized linear model analyses, adjusting for accelerometer wear time. Results: The mean RRS was 13.7±11.9 (range 0.8 to 94.3). Based on regression analysis, every hour/day spent in SB was associated with an average 2.3% increase in the RRS. In contrast, every hour/day spent in low-light, high-light, or MVPA resulted in an average 1.1%, 1.5%, and 5.2% reduction, respectively, in the RRS. A significant positive association was observed between SB and decile of RRS (trend, p<.0001); whereas, significant inverse gradients for time spent in each PA level were observed across decile of RRS (trend, p<.001 for all). Mean hours/day associated with the lowest and highest decile of RRS, respectively, were 12.0 and 13.1 for SB; 3.6 and 3.1 for low light; 1.9 and 1.4 for high light; and 1.3 and 0.6 for MVPA. These patterns of association for SB and PA with RRS were also observed when stratified by race-ethnicity and age. Conclusion: Based on objectively assessed SB and PA, this study confirms that prolonged SB is adversely related with cardiovascular health in older women. Results further suggest that even light intensity PA could have cardiovascular benefit in older women. Because a large proportion of daily activity time is spent at lower intensity among older adults, this finding has important public health implications. Prospective studies are needed to confirm these cross-sectional results.

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
John Bellettiere ◽  
Michael J LaMonte ◽  
Eileen Rillamas-Sun ◽  
Jacqueline Kerr ◽  
Kelly R Evenson ◽  
...  

Background: Evidence on sedentary behavior and cardiovascular disease (CVD) is largely based on self-reported sedentary time. Furthermore, how sedentary time is accumulated (in longer vs. shorter bouts) may be related to CVD risk but has not been tested. Methods: Women (n=5638, mean age=79±7) with no history of myocardial infarction or stroke wore accelerometers for 4-7 days and were followed for up to 4 years for incident CVD. Hazard ratios (HR) and 95% confidence intervals (CIs) for CVD and coronary heart disease (CHD) events were estimated across quartiles of sedentary time and mean sedentary bout duration using Cox proportional hazard models adjusting for covariates. Separate models evaluated associations after adding moderate-to-vigorous physical activity (MVPA) and possible mediators: body mass index, diabetes, hypertension, systolic blood pressure, fasting glucose, HDL-cholesterol, and triglycerides. We then tested whether mean bout duration was associated with increased risk for CVD and CHD among women with above median sedentary time (≥10hr/day). Results: Covariate-adjusted HRs for CVD and CHD increased across quartiles of both sedentary time and mean bout duration (Table). All CHD associations remained significant but attenuated after adjustment for possible mediators. After adjustment for MVPA, highest vs. lowest quartile HRs (CI) for CHD were 1.6 (0.7-3.4; p-trend = .08) for sedentary time and 1.8 (0.9-3.5; p-trend = .047) for mean bout duration. Among women with high sedentary time, the HRs (CI) comparing the 75 th vs. 25 th percentile of mean bout duration were 1.05 (0.95-1.15) for CVD and 1.16 (1.01-1.34) for CHD. Conclusions: Both sedentary time and mean bout duration showed independent, dose-response associations with increased risk of CVD and CHD events in older women. Among women with high sedentary time, longer mean bout duration was associated with higher CHD risk. Taken together, this provides evidence that both total sedentary time and the way it is accumulated are predictive of incident CHD.


2018 ◽  
Vol 50 (5S) ◽  
pp. 209-210
Author(s):  
Luis Adriano Lima ◽  
Diana Carolina Gonzalez ◽  
João Pedro Silva Junior ◽  
Timóteo Leandro Araujo ◽  
Sandra Mahecha Matsudo ◽  
...  

Author(s):  
Giovana Z. Mazo ◽  
Felipe Fank ◽  
Pedro S. Franco ◽  
Bruna da Silva Vieira Capanema ◽  
Franciele da Silva Pereira

The objective was to analyze the impact of social isolation on moderate physical activity and factors associated with sedentary behavior of older adults during the COVID-19 pandemic. This was a cross-sectional study involving 111 older adults (aged 71.0 ± 6.87 years). The data were collected at two time points: in November 2019 and in June 2020. There was a decline in moderate physical activity when the minutes/week were compared before and during social isolation (p < .001). Sedentary behavior was associated with the condition of living alone. Older adults who lived alone were 3.29 times more likely to spend 4 hr or more in sedentary behavior than those who lived with a partner (95% confidence interval [1.01, 10.74]). Government agencies must establish PA-related health promotion strategies, especially in developing and low-income countries. Therefore, home exercises need to be encouraged to prevent the consequences of this pandemic period.


Author(s):  
Marcel Ballin ◽  
Peter Nordström ◽  
Anna Nordström

In this cross-sectional study, the authors investigated the associations of objectively measured physical activity (PA) with the prevalence of metabolic syndrome (MetS) in older adults. Accelerometer-derived light-intensity PA, moderate to vigorous PA, and steps per day were measured in (N = 4,652) 70-year-olds in Umeå, Sweden, during May 2012–November 2019. The MetS was assessed according to the American Heart Association/ National Heart, Lung and Blood Institute criteria. The prevalence of MetS was 49.3%. Compared with the reference, the odds ratios for MetS in increasing quartiles of light-intensity PA were 0.91 (0.77–1.09), 0.75 (0.62–0.89), and 0.66 (0.54–0.80). For moderate to vigorous PA, the corresponding odds ratios were 0.79 (0.66–0.94), 0.67 (0.56–0.80), and 0.56 (0.46–0.67). For steps per day, the odds ratios were 0.65 (0.55–0.78), 0.55 (0.46–0.65), and 0.45 (0.36–0.55). In summary, this study shows that greater amounts of PA, regardless of intensity, are associated with lower odds of MetS. With the limitation of being an observational study, these findings may have implications for the prevention of MetS in older adults.


BMJ Open ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. e034645
Author(s):  
Ming-Chun Hsueh ◽  
Ru Rutherford ◽  
Chien-Chih Chou ◽  
Jong-Hwan Park ◽  
Hyun-Tae Park ◽  
...  

ObjectivesTo objectively assess light physical activity (PA), moderate-to-vigorous PA (MVPA), step counts and number of 10 min MVPA bouts and their association with physical function among older adults.DesignCross-sectional design.SettingUrban community setting in Taiwan.Participants127 Taiwanese older adults aged over 65 years (mean age=70.8±5.3 years; 72% women).Primary and secondary outcome measuresTriaxial accelerometers were used to measure PA variables for 10 hours/day for seven consecutive days. Then, five physical function components (handgrip strength, single-leg stance, 5-metre walk speed, timed up and go and sit-to-stand test) were measured. Multiple linear regressions were used to perform separate analyses for older men and women.ResultsFor older women, daily MVPA time (β: 0.39, 95% CI: 0.12, 0.64; p=0.004), daily step counts (β: 0.46, 95% CI: 0.12, 0.78; p=0.009) and number of 10 min MVPA bouts (β: 0.27, 95% CI: 0.001, 0.53; p=0.049) were positively associated with handgrip strength after adjusting for accelerometer wear time, sedentary time and other confounders. Furthermore, daily MVPA time was positively associated with a single-leg stance (β: 0.25, 95% CI: 0.02, 0.49; p=0.036) and higher daily step counts were associated with shorter walking speed performance (β: −0.31, 95% CI: −0.57, −0.001; p=0.049). None of the variables of the objectively assessed PA patterns was associated with physical function outcomes among older men due to their small sample size.ConclusionsDaily MVPA, MVPA bouts of at least 10 min and accumulated daily steps are important for improving physical function among older women. Future prospective research should establish causal associations between PA patterns and functional ability among older adults.


2020 ◽  
Author(s):  
Melker Staffan Johansson ◽  
Karen Søgaard ◽  
Eva Prescott ◽  
Jacob Louis Marott ◽  
Peter Schnohr ◽  
...  

Abstract Background: It is unclear whether walking can decrease cardiovascular disease (CVD) risk or if high intensity physical activity (HIPA) is needed, and whether the association is modified by age. We investigated how sedentary behaviour, walking, and HIPA, were associated with systolic blood pressure (SBP), waist circumference (WC), and low-density lipoprotein cholesterol (LDL-C) among adults and older adults in a general population sample using compositional data analysis. Specifically, the measure of association was quantified by reallocating time between sedentary behaviour and 1) walking, and 2) HIPA. Methods: Cross-sectional data from the fifth examination of the Copenhagen City Heart Study was used. Using the software Acti4, we estimated daily time spent in physical behaviours from accelerometer data worn 24 h/day for 7 days (i.e., right frontal thigh and iliac crest; median wear time: 6 days, 23.8 h/day). SBP, WC, and LDL-C were measured during a physical examination. Inclusion criteria were ≥5 days with ≥16 h of accelerometer recordings per day, and no use of antihypertensives, diuretics or cholesterol lowering medicine. The 24-hour physical behaviour composition consisted of sedentary behaviour, standing, moving, walking, HIPA (i.e., sum of climbing stairs, running, cycling and rowing), and time in bed. We used fitted values from linear regression models to predict the difference in outcome given the investigated time reallocations relative to the group-specific mean composition. Results: Among 1053 eligible participants, we found an interaction between the physical behaviour composition and age. Age-stratified analyses (i.e., </≥65 years; 773 adults, 280 older adults) indicated that less sedentary behaviour and more walking was associated with lower SBP among older adults only. For less sedentary behaviour and more HIPA, the results i) indicated an association with lower SBP irrespective of age, ii) showed an association with a smaller WC among adults, and iii) showed an association with a lower LDL-C in both age groups. Conclusions: Less sedentary behaviour and more walking seems to be associated with lower CVD risk among older adults, while HIPA types are associated with lower risk among adults. Therefore, to reduce CVD risk, the modifying effect of age should be considered in future physical activity-promoting initiatives.


2018 ◽  
Vol 15 (11) ◽  
pp. 811-818 ◽  
Author(s):  
Carla Elane Silva dos Santos ◽  
Sofia Wolker Manta ◽  
Guilherme Pereira Maximiano ◽  
Susana Cararo Confortin ◽  
Tânia Rosane Bertoldo Benedetti ◽  
...  

Background: To examine the level of physical activity and sedentary behavior (SB), measured with accelerometers, in older adults from a city in southern Brazil according to sociodemographic and health characteristics.Methods: The sample consisted of 425 older adults (≥63 y) from the EpiFloripa Aging Study. Light physical activity (LPA), moderate to vigorous physical activity (MVPA), and SB were measured with accelerometers over a period of 7 days.Results: The older adults spent two-thirds of the time of use in SB, one-third in LPA, and only 2.1% (95% confidence interval, 1.8–2.2) in MVPA. In the final adjusted model, lower levels of MVPA were observed for women, as well as higher SB and lower LPA and MVPA for those with higher age. There were also trends toward prolonged SB and lower LPA when participants had a higher educational level and toward lower MVPA with higher body mass index.Conclusions: Constant monitoring of physical activity levels and SB using objective measures is recommended and interventions should be directed at the groups most exposed to excessive SB and low levels of MVPA.


2017 ◽  
Vol 14 (2) ◽  
pp. 204-215
Author(s):  
Beate Henschel ◽  
Anna M. Gorczyca ◽  
Andrea K. Chomistek

Sedentary behavior is highly prevalent despite growing evidence of adverse effects on the cardiovascular and metabolic system that are independent of the level of recreational physical activity (PA). We present results for the association between sitting time and cardiovascular disease (CVD) from selected cohort and cross-sectional studies published in or after the year 2010 according to the domains where sitting time is accumulated during the day. These include TV viewing, occupational sitting, and sitting during transportation as well as overall sitting. The outcomes considered in this review are total CVD, coronary heart disease, and stroke as well as CVD risk factors—namely, hypertension, hypercholesterolemia, and type 2 diabetes and their associated biomarkers. Finally, several current issues with regard to studying the effects of sitting time on CVD are discussed, including how sedentary behavior is assessed, isotemporal substitution modeling, examination of joint associations for sitting and PA, and benefits of breaks in sitting time. Overall, the scientific evidence supports public health recommendations that encourage adults to limit their sedentary time in order to improve their cardiovascular health.


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