scholarly journals Predicting Early Mortality of Acute Ischemic Stroke

Stroke ◽  
2019 ◽  
Vol 50 (2) ◽  
pp. 349-356 ◽  
Author(s):  
Thomas Gattringer ◽  
Alexandra Posekany ◽  
Kurt Niederkorn ◽  
Michael Knoflach ◽  
Birgit Poltrum ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Stroke Unit ◽  
Functional Disability ◽  
Area Under The Curve ◽  
Early Mortality ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Derivation Cohort ◽  
Temporal Validation

Background and Purpose— Several risk factors are known to increase mid- and long-term mortality of ischemic stroke patients. Information on predictors of early stroke mortality is scarce but often requested in clinical practice. We therefore aimed to develop a rapidly applicable tool for predicting early mortality at the stroke unit. Methods— We used data from the nationwide Austrian Stroke Unit Registry and multivariate regularized logistic regression analysis to identify demographic and clinical variables associated with early (≤7 days poststroke) mortality of patients admitted with ischemic stroke. These variables were then used to develop the Predicting Early Mortality of Ischemic Stroke score that was validated both by bootstrapping and temporal validation. Results— In total, 77 653 ischemic stroke patients were included in the analysis (median age: 74 years, 47% women). The mortality rate at the stroke unit was 2% and median stay of deceased patients was 3 days. Age, stroke severity measured by the National Institutes of Health Stroke Scale, prestroke functional disability (modified Rankin Scale >0), preexisting heart disease, diabetes mellitus, posterior circulation stroke syndrome, and nonlacunar stroke cause were associated with mortality and served to build the Predicting Early Mortality of Ischemic Stroke score ranging from 0 to 12 points. The area under the curve of the score was 0.879 (95% CI, 0.871–0.886) in the derivation cohort and 0.884 (95% CI, 0.863–0.905) in the validation sample. Patients with a score ≥10 had a 35% (95% CI, 28%–43%) risk to die within the first days at the stroke unit. Conclusions— We developed a simple score to estimate early mortality of ischemic stroke patients treated at a stroke unit. This score could help clinicians in short-term prognostication for management decisions and counseling.

scholarly journals Predictors of unfavorable outcome and in-hospital mortality after ischemic stroke

2021 ◽  
Author(s):  
Gustavo Di Lorenzo Villas Boas ◽  
Maiara Silva Tramonte ◽  
Ana Claudia Pires Carvalho ◽  
Ana Elisa Vayego Fornazari ◽  
Marcos Minicucci ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Hospital Mortality ◽  
Stroke Unit ◽  
Descriptive Study ◽  
Early Mortality ◽  
Unfavorable Outcome ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Main Factor ◽  
Significant Factors

Background: stroke is the second leading cause of death and disability worldwide. The most significant factors for early mortality are age, severity of stroke (NIH stroke scale), atrial fibrillation (AF) and hypertension. Objective: elucidate the factors correlated with unfavorable outcome and mortality after ischemic stroke. Design/Setting: retrospective descriptive study conducted at the Botucatu Medical School Hospital. Methods: this study included 515 stroke patients, aged at least 18, admitted to ICU and stroke-unit between January/2017-December/2018. Baseline data, comorbidities and risk factors were collected and relation to unfavorable outcome and in-hospital mortality were evaluated. Unfavorable outcome was defined as dependency (modified Rankin Scale mRs 4–5). Results: overall, in-hospital mortality rate was 15% (77) and unfavorable outcome 36.7% (189). The patients average age was 69.18±13.08, and NIHSS at admission 9.27±8.41. NIHSS at admission and pre-morbid mRs were independently associated with unfavorable outcome, as each NIHSS point was responsible for 22% outcome increase. Both higher NIHSS and AF were independently associated with in-hospital mortality, increasing the death risk 19% and 3.5 times respectively. Conclusion: the main factor associated with overall in-hospital mortality and unfavorable outcome was stroke severity.

scholarly journals A Simple Hospital Mobility Scale for Acute Ischemic Stroke Patients Predicts Long-term Functional Outcome

2019 ◽  
Vol 33 (8) ◽  
pp. 614-622 ◽  
Author(s):  
Iara Maso ◽  
Elen Beatriz Pinto ◽  
Maiana Monteiro ◽  
Marina Makhoul ◽  
Tassiana Mendel ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Functional Outcome ◽  
Characteristic Curve ◽  
Intraclass Correlation ◽  
Prognostic Indicator ◽  
National Institutes Of Health ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Derivation Cohort

Background. Stroke patients present restriction of mobility in the acute phase, and the use of a simple and specific scale can be useful to guide rehabilitation. Objective. To validate and propose a Hospital Mobility Scale (HMS) for ischemic stroke patients as well as to evaluate the HMS as a prognostic indicator. Methods. This study was performed in 2 phases: in the first, we developed the HMS content, and in the second, we defined its score and evaluated its psychometric properties. We performed a longitudinal prospective study consisting of 2 cohorts (derivation and validation cohorts). The data were collected in a stroke unit, and the following scales were applied during hospitalization: National Institutes of Health Stroke Scale to quantify stroke severity and the HMS to verify the degree of mobility. The primary outcome was the proportion of unfavorable functional outcomes, defined as a modified Barthel Index of <95. Results. We defined 3 tasks for HMS: sitting, standing, and gait. In the derivation cohort, the HMS presented an accuracy of 84.5% measured using the area under the receiver operating characteristic curve (95% CI = 78.3-90.7; P < .001), whereas in the validation cohort the accuracy was 87.8% (95% CI = 81.9%-93.7%; P < .001). The HMS presented a large standardized effect size (1.41) and excellent interexaminer agreement (intraclass correlation coefficient = 0.962; 95% CI = 0.917-0.983; P < .001). Conclusion. The HMS was able to predict accurately the functional outcome of poststroke patients, presented excellent interexaminer agreement, and was sensitive in detecting changes.

scholarly journals WMH and long-term outcomes in ischemic stroke

Neurology ◽  
2019 ◽  
Vol 92 (12) ◽  
pp. e1298-e1308 ◽  
Author(s):  
Marios K. Georgakis ◽  
Marco Duering ◽  
Joanna M. Wardlaw ◽  
Martin Dichgans
Keyword(s):  
Ischemic Stroke ◽  
Functional Impairment ◽  
Recurrent Stroke ◽  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Stroke Recurrence ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Increased Risk

ObjectiveTo investigate the relationship between baseline white matter hyperintensities (WMH) in patients with ischemic stroke and long-term risk of dementia, functional impairment, recurrent stroke, and mortality.MethodsFollowing the Meta-analysis of Observational Studies in Epidemiology and Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PROSPERO protocol: CRD42018092857), we systematically searched Medline and Scopus for cohort studies of ischemic stroke patients examining whether MRI- or CT-assessed WMH at baseline are associated with dementia, functional impairment, recurrent stroke, and mortality at 3 months or later poststroke. We extracted data and evaluated study quality with the Newcastle–Ottawa scale. We pooled relative risks (RR) for the presence and severity of WMH using random-effects models.ResultsWe included 104 studies with 71,298 ischemic stroke patients. Moderate/severe WMH at baseline were associated with increased risk of dementia (RR 2.17, 95% confidence interval [CI] 1.72–2.73), cognitive impairment (RR 2.29, 95% CI 1.48–3.54), functional impairment (RR 2.21, 95% CI 1.83–2.67), any recurrent stroke (RR 1.65, 95% CI 1.36–2.01), recurrent ischemic stroke (RR 1.90, 95% CI 1.26–2.88), all-cause mortality (RR 1.72, 95% CI 1.47–2.01), and cardiovascular mortality (RR 2.02, 95% CI 1.44–2.83). The associations followed dose-response patterns for WMH severity and were consistent for both MRI- and CT-defined WMH. The results remained stable in sensitivity analyses adjusting for age, stroke severity, and cardiovascular risk factors, in analyses of studies scoring high in quality, and in analyses adjusted for publication bias.ConclusionsPresence and severity of WMH are associated with substantially increased risk of dementia, functional impairment, stroke recurrence, and mortality after ischemic stroke. WMH may aid clinical prognostication and the planning of future clinical trials.

Abstract W MP106: Clinical Effectiveness of Anticoagulation with Warfarin among Ischemic Stroke Patients with Atrial Fibrillation: Findings from the Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Ying Xian ◽  
Jingjing Wu ◽  
Emily C O’Brien ◽  
Gregg C Fonarow ◽  
DaiWai M Olson ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Ischemic Stroke ◽  
Warfarin Therapy ◽  
Stroke Severity ◽  
Stroke Survivors ◽  
Stroke Patients ◽  
Long Term Outcomes ◽  
Warfarin Treatment

Background: Oral anticoagulation is recommended for ischemic stroke patients with atrial fibrillation, based on clinical trials done in selected populations. However, little is known about whether the clinical benefit of warfarin is preserved outside the clinical trial setting, especially in older patients with ischemic stroke. Methods: PROSPER, a PCORI-funded research program designed by stroke survivors and stakeholders, used American Heart Association Get With The Guidelines (GWTG)-Stroke data linked to Medicare claims to evaluate the association between warfarin treatment at discharge and long-term outcomes among ischemic stroke survivors with atrial fibrillation (AF) and no contraindication to or prior anticoagulation therapy. The primary outcome prioritized by patients was home-time (defined as days spent alive and not in inpatient post-acute care facility) within 2-year follow-up after discharge. Results: Of 12,552 ischemic stroke patients with AF admitted from 2009-2011, 11,039 (88%) received warfarin treatment at discharge. Compared with those not receiving any anticoagulation, warfarin-treated patients were slightly younger (mean 80 vs. 83, p<0.001), less likely to have a history of prior stroke or coronary artery disease, but had similar stroke severity as measured by NIHSS (median 5 [IQR 2-12] vs. 6 [2-13], p=0.09). After adjustment for all observed baseline characteristics using propensity score inverse probability weighting method, patients discharged on warfarin therapy had 45 more days of home-time during 2-year follow-up than those not receiving any oral anticoagulant (513 vs. 468 days, p<0.001). Warfarin use was also associated with a lower risk of all-cause mortality, cardiovascular readmission or death, and ischemic stroke (Table). Conclusions: Among ischemic stroke patients with atrial fibrillation, warfarin therapy was associated with improved long-term outcomes.

scholarly journals Predictors of 30-day and 90-day mortality among hemorrhagic and ischemic stroke patients in urban Uganda: a prospective hospital-based cohort study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Gertrude Namale ◽  
Onesmus Kamacooko ◽  
Anthony Makhoba ◽  
Timothy Mugabi ◽  
Maria Ndagire ◽  
...  
Keyword(s):  
Cohort Study ◽  
Ischemic Stroke ◽  
Acute Phase ◽  
Hemorrhagic Stroke ◽  
Functional Disability ◽  
Stroke Severity ◽  
Protective Effects ◽  
Stroke Patients ◽  
Post Stroke ◽  
Gcs Score

Abstract Background We report here on a prospective hospital-based cohort study that investigates predictors of 30-day and 90-day mortality and functional disability among Ugandan stroke patients. Methods Between December 2016 and March 2019, we enrolled consecutive hemorrhagic stroke and ischemic stroke patients at St Francis Hospital Nsambya, Kampala, Uganda. The primary outcome measure was mortality at 30 and 90 days. The modified Ranking Scale wasused to assess the level of disability and mortality after stroke. Stroke severity at admission was assessed using the National Institute of Health Stroke Scale (NIHSS) and Glasgow Coma Scale (GCS). Examination included clinical neurological evaluation, laboratory tests and brain computed tomography (CT) scan. Kaplan-Meier curves and multivariate Cox proportional hazard model were used for unadjusted and adjusted analysis to predict mortality. Results We enrolled 141 patients; 48 (34%) were male, mean age was 63.2 (+ 15.4) years old; 90 (64%) had ischemic and 51 (36%) had hemorrhagic stroke; 81 (57%) were elderly (≥ 60 years) patients. Overall mortality was 44 (31%); 31 (23%) patients died within the first 30 days post-stroke and, an additional 13 (14%) died within 90 days post-stroke. Mortality for hemorrhagic stroke was 19 (37.3%) and 25 (27.8%) for ischemic stroke. After adjusting for age and sex, a GCS score below < 9 (adjusted hazard ratio [aHR] =3.49, 95% CI: 1.39–8.75) was a significant predictor of 30-day mortality. GCS score < 9 (aHR =4.34 (95% CI: 1.85–10.2), stroke severity (NIHSS ≥21) (aHR = 2.63, 95% CI: (1.68–10.5) and haemorrhagic stroke type (aHR = 2.30, 95% CI: 1.13–4.66) were significant predictors of 90-day mortality. Shorter hospital stay of 7–13 days (aHR = 0.31, 95% CI: 0.11–0.93) and being married (aHR = 0.22 (95% CI: 0.06–0.84) had protective effects for 30 and 90-day mortality respectively. Conclusion Mortality is high in the acute and sub-acute phase of stroke. Low levels of consciousness at admission, stroke severity, and hemorrhagic stroke were associated with increased higher mortality in this cohort of Ugandan stroke patients. Being married provided a protective effect for 90-day mortality. Given the high mortality during the acute phase, critically ill stroke patients would benefit from early interventions established as the post-stroke- standard of care in the country.

scholarly journals Efficacy of Combined Antithrombotic, Statins and Anti-Hypertensive Drugs in Acute Ischemic Stroke

2015 ◽  
Vol 53 (197) ◽  
pp. 5-11 ◽  
Author(s):  
Ramesh Sharma Poudel ◽  
Lekhjung Thapa ◽  
Shakti Shrestha ◽  
Dipendra Khatiwada ◽  
Nijan Upadhyay ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Functional Disability ◽  
Antihypertensive Drugs ◽  
Functional Independence ◽  
Stroke Severity ◽  
Medical Sciences ◽  
Stroke Patients ◽  
Alcohol Consumer ◽  
First Time

Introduction: Anti-thrombotic, statins and antihypertensive drugs are commonly used for the management of acute ischemic stroke in Nepal but there is no evidence regarding their efficacy in our context. This study aims to explore the efficacy of these combined medications (anti-thrombotic, statins and antihypertensive drugs) in acute ischemic stroke patients for the first time and to assess the risk factors present in those patients. Methods: The study was conducted on 37 acute ischemic stroke patients admitted and treated at the Neurology Department of College of Medical Sciences-Teaching Hospital, Chitwan, Nepal and they were followed at three months (90±10 days). The initial stroke severity and functional disability were evaluated at admission and at 3 months using National Institute of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) respectively. The outcome parameters were functional independence (mRS≤2) and mortality at three months (mRS=6). Frequency distribution, Mann-Whitney U-test and χ2 test were performed for statistical analysis. Results: Out of 37 patients, 27 (73%) were Smoker, 22 (59.5%) had hypertension and 19 (51.4%) were alcohol consumer. The stroke severity on admission was statistically significant with functional independence (P=0.003) and mortality (P=0.015) at three month. Similarly, Rankin grade on admission was statistically significant with functional independence (P=0.001) and mortality (P=0.048) at three month. At three months, 20 (69%) survived patients were independent while mortality was seen in eight (21.6%) patients. Conclusions: The management of acute ischemic stroke with combined anti-thrombotic, statins and antihypertensive drugs seems promising and efficacious in mild to moderately severe ischemic stroke. Keywords: antihypertensive; anti-thrombotic; efficacy ; statins; stroke.

Abstract P282: First-ever Ischemic Stroke in the Very Elderly: Trends, Characteristics and Outcome in a National Registry

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Alex Y Gur ◽  
David Tanne ◽  
Natan M Bornstein ◽  
Ron Milo ◽  
Eitan Auriel ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Elderly Patients ◽  
Functional Disability ◽  
National Registry ◽  
Elderly Subjects ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Very Elderly ◽  
Old Patients ◽  
Very Old

Background: The incidence of ischemic stroke significantly increases with age. With increasing life expectancy, very old subjects will constitute the majority of stroke patients. However, epidemiological and clinical features of very elderly patients with stroke are still uncertain. Our aim was to study the patients' characteristics, outcome and trends in the very elderly (aged ≥ 85 years) in comparison with patients aged 65–84 years with a first-ever ischemic stroke in the National Acute Stroke Israeli Survey (NASIS) registry. Methods: The NASIS registry is a nationwide prospective hospital-based study performed triennially (2004, 2007, 2010). Patients with ischemic stroke aged ≥85 years were compared with those 65–84 years old regarding their baseline characteristics, stroke severity, etiology of stroke and stroke outcomes. Stroke severity was determined according to the National Institute of Health stroke scale (NIHSS) score and functional disability using the modified Rankin scale (mRS). Logistic regression analyses were used in the comparison of outcomes adjusting for potential confounders. Trends in patients' characteristics and stroke outcome were studied. Results: A first-ever ischemic stroke was diagnosed in 3125 patients. The proportion of very elderly (≥85 years) patients among the NASIS population increased from 18.3% in 2004 to 19.9% in 2007 and 24.5% in 2010 (p=0.005). The percentage of women was higher in patients aged ≥85 years (p<0.0001). Atrial fibrillation, congestive heart disease and prior disability were significantly more prevalent in the very elderly. The very elderly presented with more severe strokes: 36.3% of the ≥85 years-old patients had NIHSS≥11 compared with 22.0% in the younger age group. Adjusted rates of in-hospital complications [OR (95% CI=1.7 (1.3–2.2)] and severe disability or death (mRS>3) [1.4 (1.0–1.9)] were increased for very elderly patients. In the analysis of trends by registry period, rates of dyslipidemia increased from 25.4% in 2004 to 63.7% in 2010 (p for trend<0.0001) and hypertension increased from 74.8% in 2004 to 90.5% in 2010 (p for trend=0.0004). A significant decrease in the rate of in-hospital mortality among the very old patients is evident: rates decreased from 18.7% in 2004 to 5.7% in 2010 (p for trend=0.0005). Conclusions: There is an increasing proportion of very elderly subjects, mostly women, among first-ever ischemic stroke patients. Current information on age specific aspects of stroke in the very elderly is crucial to set up successful prevention pathways and implementing well-organized stroke care for this population.

scholarly journals Association of High Blood Homocysteine and Risk of Increased Severity of Ischemic Stroke Events

2018 ◽  
Vol 28 (01) ◽  
pp. 034-038 ◽  
Author(s):  
Al Rasyid ◽  
Mohammad Kurniawan ◽  
Taufik Mesiano ◽  
Rakhmad Hidayat ◽  
Salim Harris
Keyword(s):  
Ischemic Stroke ◽  
Cross Sectional Study ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Stroke Outcomes ◽  
Future Studies ◽  
Significant Difference ◽  
Short And Long Term

AbstractStroke is the leading cause of death and disability in the world as well as in Indonesia. Initial stroke severity is an important factor that affects short- and long-term stroke outcomes. This cross-sectional study was conducted in Cipto Mangunkusumo Hospital from July 2017 to January 2018 to investigate the factors that affect stroke severity. A total of 77 acute ischemic stroke patients were divided into three groups, which include low blood homocysteine levels (< 9 μmol/L), moderate blood homocysteine levels (9–15 μmol/L), and high blood homocysteine levels (> 15 μmol/L). The acquired data were analyzed using Kruskal–Wallis test and a significant difference of initial National Institute of Health Stroke Scale (NIHSS) and blood homocysteine levels (H = 13.328, p = 0.001) were seen, with a mean rank of 25.86 for low blood homocysteine levels, 33.69 for moderate blood homocysteine levels, and 48.94 for high blood homocysteine levels. The patients were then divided into two groups based on the NIHSS (≤5 and > 5) to calculate the risk correlation of blood homocysteine levels and NIHSS by using regression. We found that patients with high blood homocysteine levels had 14.4 times higher risk of having NIHSS > 5 compared with those with low blood homocysteine levels (p = 0.002, 95% confidence interval [CI] [2.714–76.407]), and 3.9 times higher risk compared with those with moderate blood homocysteine levels (p = 0.011, 95% CI [1.371–11.246]). We concluded that homocysteine is a risk factor for a higher stroke severity. Future studies to evaluate the usefulness of homocysteine-lowering therapy in stroke patients are recommended.

scholarly journals Does hemorrhagic transformation in patients with ischemic stroke predict worse functional outcomes?

2021 ◽  
Author(s):  
vã Taiuan Fialho Silva ◽  
Vinícius Bessa Mendez ◽  
Fernanda Ferreira de Abreu ◽  
Alice Monteiro Soares Cajaíba ◽  
Pedro Antonio Pereira de Jesus
Keyword(s):  
Ischemic Stroke ◽  
Functional Outcomes ◽  
Stroke Unit ◽  
Functional Disability ◽  
Hemorrhagic Transformation ◽  
Stroke Patients ◽  
Short Term ◽  
Relevant Variables ◽  
Patient Prognosis ◽  
The Impact

Background: Hemorrhagic transformation (HT) is a complication of stroke described as cause of early neurologic deterioration. Previous studies are discordant about the real impact of HT on stroke prognosis. Objectives: to describe the impact of HT in patient prognosis. Design and setting: Prospective cohort with acute ischemic stroke patients from a Stroke Unit, admitted between 2017 to 2020. Methods: All patients performed a brain computer tomography (CT) scan on their arrival and 24 hours later. Patients with or without HT were compared regarding functional 90-day outcome using the modified rankin scale (mRS). Functional disability was considered as mRS < 2. Results: 383 patients were included, mean age was 62,2 (±13,8), which 54,3% were male, 80,9% hypertensive, 33,1% diabetics and 27,2% were dyslipidemic. HT occurred in 11,5% patients (n= 44) increasing the risk of poorer functional outcome in discharge [RR= 1,47; (IC95% 1,25–1,72), in 30 days [RR = 1,54; (IC95% 1,01-1,92)], and in 90 days [RR= 1,39; (IC95% 1,01-1,92)]. Multivariate analysis HT was not associated with worse outcome in 90 days (mRS>2) [OR= 1,01; (IC95% 0,44–2,33) p= 0,987], when adjusted to age, sex, NIHSS, ASPECTS, trombolysis and other relevant variables. Conclusion: Although the occurrency of HT had been associated with worse short-term outcomes, patients seems to recover from disability over time.

scholarly journals Does hemorrhagic transformation in patients with ischemic stroke predict worse functional outcomes?

2021 ◽  
Author(s):  
Ivã Taiuan Fialho Silva ◽  
Vinícius Bessa Mendez ◽  
Fernanda Ferreira de Abreu ◽  
Alice Monteiro Soares Cajaíba ◽  
Pedro Antonio Pereira de Jesus
Keyword(s):  
Ischemic Stroke ◽  
Functional Outcomes ◽  
Stroke Unit ◽  
Functional Disability ◽  
Hemorrhagic Transformation ◽  
Stroke Patients ◽  
Short Term ◽  
Relevant Variables ◽  
Patient Prognosis ◽  
The Impact

Background: Hemorrhagic transformation (HT) is a complication of stroke described as cause of early neurologic deterioration. Previous studies are discordant about the real impact of HT on stroke prognosis. Objectives: to describe the impact of HT in patient prognosis. Design and setting: Prospective cohort with acute ischemic stroke patients from a Stroke Unit, admitted between 2017 to 2020. Methods: All patients performed a brain computer tomography (CT) scan on their arrival and 24 hours later. Patients with or without HT were compared regarding functional 90-day outcome using the modified rankin scale (mRS). Functional disability was considered as mRS < 2. Results: 383 patients were included, mean age was 62,2 (±13,8), which 54,3% were male, 80,9% hypertensive, 33,1% diabetics and 27,2% were dyslipidemic. HT occurred in 11,5% patients (n= 44) increasing the risk of poorer functional outcome in discharge [RR= 1,47; (IC95% 1,25–1,72), in 30 days [RR = 1,54; (IC95% 1,01-1,92)], and in 90 days [RR= 1,39; (IC95% 1,01-1,92)]. Multivariate analysis HT was not associated with worse outcome in 90 days (mRS>2) [OR= 1,01; (IC95% 0,44–2,33) p= 0,987], when adjusted to age, sex, NIHSS, ASPECTS, trombolysis and other relevant variables. Conclusion: Although the occurrency of HT had been associated with worse short-term outcomes, patients seems to recover from disability over time.

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