Abstract 1122‐000026: Factors Associated with Gender Differences in Patients with Lewy Body Dementia

Author(s):  
Chika P Onuoha ◽  
Lidadi Agbomi ◽  
Nneoma Madubuike ◽  
Oreoluwa Coker ◽  
Samuel I Nathaniel ◽  
...  

Introduction : Several studies have investigated gender differences in patients with Lewy Body Dementia (LBD), however, whether the observed differences are associated with demographic and pharmacological factors is not fully understood. The current study tested the hypothesis that specific demographic or pharmacological factors may contribute to the observed gender difference. Methods : A 5‐year data collected from a regional registry from 608 LBD patients including 332 men and 276 women were analyzed. Factors associated with men and women patients with LBD were determined using the logistic regression model. Multicollinearity was evaluated using variance inflation factors (VIFs), with values greater than five suggestive of multicollinearity Results : The results indicate that Caucasian men (94.3% vs 83.3%) were more likely to present with LBD. In the adjusted analysis, increasing age (OR = 1.042, 95% CI, 1.025‐ 1.058, P ˂ 0.001) was more likely to be associated with women with LBD, while olanzapine (OR = 2.871, 95% CI, 1.902‐4.334, P˂ 0.001), buspirone (OR = 2.388, 95% CI, 1.527‐3.735, P˂ 0.001), escitalopram (OR = 1.444, 95% CI, 1.079‐1.932, P = 0.014) and tobacco use (OR = 1.424, 95% CI, 1.075‐1.887, P = 0.014) were associated with men with LBD Conclusions : More men presented with LBD compared to women. Our findings reveal specific demographic and pharmacological factors that contribute to gender differences among LBD patients.

Author(s):  
Nneoma Madubuike ◽  
Lidadi L Agbomi ◽  
Chika P Onuoha ◽  
Oreoluwa Coker‐Ayo ◽  
Samuel Nathaniel ◽  
...  

Introduction : Gender differences in dementia patients and Parkinson’s Disease have been investigated extensively; however, factors that contribute to gender differences in Parkinson’s Disease with Dementia patients (PDD) is not fully understood. In this study, we tested the hypothesis that specific, demographic, and pharmacological factors may be associated with men and women patients with PDD, and contribute to gender differences. Methods : Data collected for 5 years from 7594 PDD patients was analyzed using univariate analysis to determine different factors associated with men or women with PDD. Multicollinearity interactions between independent variables in the model were examined using variance inflation factors Results : Overall, 55.22% of the PDD patients were men while 44.77% were women. In the adjusted analysis, Aripiprazole (OR = 0.581, 95% CI, 0.302‐1.118, P = 0.104), ETOH (OR = 0.371, 95% CI, 0.260‐0.531, P<0.001) African American (0.249, 95% CI, 0.088‐0.703, P = 0.009) with PD were more likely to be men. The use of Aripiprazole (OR = 0.195, 95% CI, 0.06‐0.631, P = 0.006), Escitalopram (OR = 0.651, 95% CI, 0.468‐0.906, P = 0.011), and Tobacco (OR = 0.620, 95% CI, 0.444‐0.866, P = 0.005) were associated with women. Conclusions : This study showed that women presented fewer cases of PDD than men. The current study reveals gender differences in PDD patients associated with specific demographic and pharmacological factors


Author(s):  
Lidadi L Agbomi ◽  
Nneoma T Madubuike ◽  
Oreoluwa Coker‐Ayo ◽  
Chika P Onuoha ◽  
Samuel I Nathaniel ◽  
...  

Introduction : Gender differences in dementia patients have been investigated extensively, however, demographic, risk, and pharmacological factors associated with gender differences in dementia patients associated with Lewy Body Dementia(LBD) and Parkinson’s disease with dementia (PDD) are not fully understood. We tested the hypothesis that specific factors may contribute to the observed gender differences in LBD and PDD patients. Methods : A 5‐year retrospective data analytical study was conducted using 4526 men and 3676 women collected from a regional hospital database. We performed logistic regression analysis to determine factors associated with gender differences in LBD and PDD patients. Multicollinearity and significant interactions between independent variables in the model were examined using variance inflation factors, while a Cox & Snell classification was applied to check the model fitness. Results : In the adjusted analysis, African‐American men (AAM) (OR = 0.249, 95% CI, 0.088‐0.703, P = 0.009) were more likely to present with PDD, while women with increasing age (OR = 1.042, 95% CI, 1.025‐1.058, P<0.002) were more likely to present with LBD. Escitalopram was associated with LBD in men (OR = 1.444, 95% CI, 1.079‐1.932, P = 0.014) and PDD in women (OR = 0.651, 95% CI, 0.468‐0.906, P = 0.011). Conclusions : Our findings revealed gender differences in LBD and PDD. More men presented with. PDD based on race, while women presented with LBD more based on age.


2017 ◽  
Vol 45 (6) ◽  
pp. 1029-1042 ◽  
Author(s):  
Na Zhang ◽  
Jian Zhang ◽  
Jing Wang

To expand the business ethics research field, and to increase society's understanding of Chinese insurance agents' business ethics, we investigated how gender differences are related to agents' business ethical sensitivity and whether or not these relationships are moderated by empathy. Through a regression analysis of the factors associated with the business ethical sensitivity of 417 Chinese insurance agents, we found that gender played an important role in affecting business ethical sensitivity, and empathy significantly affected business ethical sensitivity. Furthermore, empathy had a moderating effect on the relationship between gender and business ethical sensitivity. Both men and women with strong empathy scored high on business ethical sensitivity; however, men with strong empathy had higher levels of business ethical sensitivity than did women with little empathy. The findings add to the literature by providing insight into the mechanisms responsible for the benefits of empathy in increasing business ethical sensitivity.


2016 ◽  
Vol 63 (13) ◽  
pp. 1777-1803 ◽  
Author(s):  
Jennifer Roark ◽  
Kelly E. Knight ◽  
Heather Olson ◽  
Heidi DeSandre

This article investigates how different factors of a domestic violence incident impact the likelihood of a child abuse charge within the context of domestic violence arrests. Data from 5,148 domestic violence arrests were used to test whether domestic violence-, incident-, and child-based predictors increased the likelihood of a child abuse charge. Logistic regression models of gender-stratified samples were employed to test for gender differences among domestic violence arrestees. The results demonstrated predictors affected men’s odds of a child abuse charge when compared with women. For men and women, children witnessing the domestic violence incident had the largest impact on a child abuse charge. These results contribute to the underdeveloped area of police response to child abuse in domestic violence cases.


2011 ◽  
Vol 56 (02) ◽  
pp. 215-237 ◽  
Author(s):  
YOKO NIIMI ◽  
BARRY REILLY

This paper investigates the role of gender in remittance behavior among migrants using the 2004 Vietnam Migration Survey data. The gender dimension to remittance behavior has not featured strongly in the existing literature and our findings thus contain novel appeal. In addition, we use estimates from both homoscedastic and heteroscedastic tobit models to decompose the raw gender difference in remittances into treatment and endowment components. We find little evidence that gender differences in remittances are attributable to behavioral differences between men and women, and this finding is invariant to whether the homoscedastic or heteroscedastic tobit is used in estimation.


Author(s):  
Samuel I Imeh‐Nathaniel ◽  
Oreoluwa O Coker‐Ayo ◽  
Liddy Agbomi ◽  
Nneoma Madubike ◽  
Chika Pamela ◽  
...  

Introduction : Alzheimer dementia (AD) has been reported in both men and women. However, factors contributing to gender differences are not fully understood. We tested the hypothesis that specific pharmacological, demographic, and risk factors contribute to gender difference in AD. Methods : A retrospective analytical approach was used to analyze data from 12,632 AD patients, comprising 4,584 men and 8,048 women. Univariate and multivariate analyses determined the factors contributing to the gender difference in AD patients. Results : About 36% of AD patients were men, and 64% were women. Citalopram (OR = 1.187, 95% CI, 1.044 – 1.350, P = 0.009) was associated with men, while escitalopram (OR = 1.213, 95% CI, 1.119 – 1.315, P<0.001) was associated with women. In both men and women, increasing age (OR = 1.075, 95% CI, 1.071 – 1.079, P<0.001/OR = 1.096, 95% CI, 1.093 – 1.100, P<0.001), tobacco use (OR = 1.150, 95% CI, 1.054 – 1.254, P = 0.002/OR = 1.150, 95% CI, 1.073 – 1.233, P<0.001), and black patients (OR = 2.380, 95% CI, 2.120 – 2.674, P<0.001/OR = 1.395, 95% CI, 1.268 – 1.535, P<0.001) were associated with AD. Conclusions : Our findings reveal similarities and differences in factors associated with both men and women AD patients, suggesting the development of management strategies for the care of AD.


2019 ◽  
Vol 100 (2) ◽  
pp. 151-172
Author(s):  
Eileen M. Ahlin

There is relatively little literature examining risk factors associated with sexual victimization among youth in custody. The current study explored whether risk of forced sexual victimization among youth in custody differs by gender or perpetrator. Using data from a sample of 8,659 youth who participated in the National Survey of Youth in Custody, multivariate logistic regression models were employed to investigate gender differences in risk factors associated with overall forced sexual victimization and staff-on-inmate and inmate-on-inmate forced sexual victimization. Findings suggest that gender differences are more pronounced when perpetrator type is considered.


2021 ◽  
Author(s):  
Steffen Andersen ◽  
Julie Marx ◽  
Kasper Meisner Nielsen ◽  
Lise Vesterlund

Abstract Negotiations over real estate show that men secure better prices than women. However, gender differences decrease when improving controls for the property's value, and is eliminated when controlling for unobserved heterogeneity in a repeated-sales sample. Rather than evidence of differences in negotiation, price differences result from men and women demanding different properties. Consistently, we find no gender difference in sales prices secured for inherited property. Provided appropriate controls, men and women fare equally well when negotiating over real estate. Our study demonstrates that inference on gender differences in negotiation relies critically on controlling for the value of the negotiated item.


2020 ◽  
Vol 64 (1) ◽  
pp. 79-83
Author(s):  
Łukasz Mazurek ◽  
Alfonso Carbonero ◽  
Maciej Skrzypczak ◽  
Stanisław Winiarczyk ◽  
Łukasz Adaszek

AbstractIntroductionThe aim of the study was to establish the prevalence of Bartonella spp. in cats in eastern Poland, and to determine the factors associated with the infection.Material and MethodsPCRs were performed to detect Bartonella DNA in the whole blood of 672 cats from four regions in eastern Poland (the Lublin, Podlasie, Masovian, and Subcarpathian provinces). The association between the previously selected variables and the dependent variable (presence of Bartonella DNA) was investigated using a logistic regression model.ResultsThe overall prevalence of infection was 40.48%. All PCR positive cats were infected with B. henselae. The living conditions of the animals (free outdoor roaming), mixed breed cats, Subcarpathian region, and absence of tick control were significant risk factors associated with Bartonella infection at a 95% confidence level.ConclusionCats in eastern Poland appear to be at risk of a bartonellosis epizootic. Factors which seem to impact the likelihood of infection in cats and factors which seem not to impact it have been suggested. We advocate additional research into the ways bartonellosis spreads, its geographical scope, and the factors that favour its development.


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