Surgical Outcomes of Solid Pseudopapillary Neoplasm of the Pancreas: A Single Institution's Experience for the Last Ten Years

2012 ◽  
Vol 78 (2) ◽  
pp. 216-219 ◽  
Author(s):  
Jin Suk Lee ◽  
Hyung Joon Han ◽  
Sae Byeol Choi ◽  
Cheol Woong Jung ◽  
Tae Jin Song ◽  
...  
Keyword(s):  
Surgical Outcomes ◽  
Surgical Excision ◽  
Clinicopathological Characteristics ◽  
Good Prognosis ◽  
Pancreatic Tumors ◽  
Resection Margins ◽  
Solid Pseudopapillary Neoplasm ◽  
Complete Surgical Excision ◽  
Type Of Surgery

Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare neoplasm that accounts for about 1 to 2 per cent of all pancreatic tumors. The aim of this study was to delineate the clinicopathological characteristics and surgical outcomes of solid pseudopapillary neoplasm of the pancreas. We retrospectively reviewed the clinicopathological characteristics and surgical outcomes of 18 patients who underwent surgery for SPN of the pancreas between January 1, 2001 and November 1, 2010. The patient group was comprised of 14 females and four males and the median patient age at diagnosis was 32.4 years (range 10∼68 years). Eleven of the 18 patients were symptomatic at the time of diagnosis. The type of surgery was selected according to the location and presentation of the tumor. The resection margins were negative in all patients. One patient had distant metastasis and recurrent mass node repetitively. She underwent seven operations for recurrence of SPN during the follow-up period of 218 months. Complete surgical excision is the treatment of choice for SPN of the pancreas and can give a good prognosis. Although sometimes patients have repetitive metastases or recurrences, patients undergoing complete surgical excision of the tumor will have a good outcome.

scholarly journals Giant Cell Reparative Granuloma of the Orbit: Clinicopathological Characteristics and Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Álvaro Bengoa-González ◽  
Enrique Mencía-Gutiérrez ◽  
Beatriz Alonso-Martín ◽  
Bianca-Maria Laslău ◽  
Elena Salvador ◽  
...  
Keyword(s):  
Giant Cell ◽  
Surgical Excision ◽  
Clinicopathological Characteristics ◽  
Giant Cell Reparative Granuloma ◽  
First Case ◽  
Complete Surgical Excision ◽  
Cranial Fossa ◽  
Histopathologic Analysis ◽  
Fluid Levels

Giant cell reparative granuloma (GCRG) is a rare fibroosseous lesion uncommonly seen in the orbital area. Although benign, it is known to be recurrent and locally destructive. We report two cases of GCRG of the orbit. In both cases, computed tomography revealed a heterogeneously growing well-defined mass, arising from the roof of the orbit, affecting the cortex, and invading the orbit. In the first case, the mass extended into the anterior cranial fossa. Magnetic resonance imaging with gadolinium showed, in both cases, a cystic character of the lesion with fluid levels. The surgical treatment was performed via an upper crease incision. An ultrasonic aspirator system was used to remove the tumor tissue and its extension into cranial fossa. Careful histopathologic analysis established the diagnosis of GCRG. Symptoms resolved completely with no evidence of recurrence after a follow-up of 18 and 14 months, respectively. We present the clinicopathological and radiological findings, and we describe the surgical approach. As a rare entity, GCRG of the orbit should be considered in differential diagnosis of fibroosseous orbital masses. Complete surgical excision carries a low risk of recurrence.

scholarly journals Solid pseudopapillary tumor of the pancreas: clinical-pathological features and management of 13 cases

2017 ◽  
Vol 90 (2) ◽  
pp. 171-178 ◽  
Author(s):  
Ovidiu Vasile Bochis ◽  
Madalina Bota ◽  
Emilia Mihut ◽  
Rares Buiga ◽  
Dan Samoila Hazbei ◽  
...  
Keyword(s):  
Pathological Condition ◽  
Demographic Data ◽  
Surgical Excision ◽  
The Body ◽  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Young Females ◽  
Complete Surgical Excision ◽  
The Mean

Background and aim. Solid pseudopapillary tumor (SPT) of the pancreas is a rare pathological condition, representing less than 3% of all exocrine pancreatic tumors. SPT usually occurs in young females, without notable symptoms, with a low malignant potential and excellent prognosis.Method. We conducted a retrospective study during the period January 2005 - January 2015. SPT patients admitted in our institution were reviewed by describing demographic data, clinico-pathologic and radiological features, therapeutic management and prognosis records.Results. Thirteen patients with SPT were identified (10 females), with a median age of 30 years. The main clinical presentation was abdominal pain (92.3%). The tumor was mostly located in the body or tail of the pancreas (77%), and the mean size was 8.2 cm. Regarding the surgical approach there were 5 distal pancreatectomies with splenectomy, 3 body and tail pancreatectomies, 2 body and tail pancreatectomies with splenectomy, 2 pancreato-duodenectomy, 1 partial enucleation and of all only 2 partial resections. Postoperative hematoxylin- eosin staining and immunohistochemistry confirmed the diagnosis in all cases. None of the patients had lymph nodes metastases. Only one local invasion. There was one case of death due to postoperative complications. Four cases followed adjuvant systemic chemotherapy. The mean follow-up was 18 months, without evidence of recurrence during this period.Conclusion. SPT should always be considered in the differential diagnosis in young women with a pancreatic tumor. Complete surgical excision is the treatment of choice, and is usually curative. The decision to administer systemic therapy must be individualized. Malignant behavior and late recurrences mandates long-term follow-up for patients with SPT.

scholarly journals Chondrosarcoma of the Nasal Septum—A Rare Subsite: Case Report with Review of Literature

2021 ◽  
Vol 42 (05) ◽  
pp. 506-509
Author(s):  
Nidhi Gupta ◽  
Awadhesh Kumar Pandey ◽  
Kislay Dimri ◽  
Surinder K Singhal ◽  
Neeraj Rathee ◽  
...  
Keyword(s):  
Nasal Septum ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Metastatic Potential ◽  
Young Female ◽  
Resection Margins ◽  
Diagnostic Dilemma ◽  
Complete Surgical Excision ◽  
Grade Ii ◽  
Common Primary Malignant Bone

AbstractChondrosarcomas are the second most common primary malignant bone tumors. Head and neck chondrosarcomas constitute less than 10% of these tumors, rarely arising from the nasal septum. These are locally aggressive malignant tumors arising from the cartilaginous framework of the nasal septum. Rarity of the tumor coupled with nonspecific symptoms makes it a diagnostic dilemma. Diagnosis requires endoscopy, radiology, and final histopathology for confirmation. Treatment is mainly surgical, requiring complete surgical excision with clear margins. Radiation has a role in unresectable tumors or for tumors with positive margins after surgery. Survival depends on the grade of tumor that predicts the metastatic potential of the tumor. We present a rare case of chondrosarcoma arising from the nasal septum in a 29-year-old young female presenting with complaints of nasal obstruction. Computed tomography was suggestive of a calcified cartilaginous tumor arising from the nasal septum. Endoscopic excision was done and postoperative histopathology showed grade II chondrosarcoma with clear margins. No adjuvant treatment was given to our patient and 2 years post-excision patient is disease free.To conclude, chondrosarcoma of the nasal septum is a rare tumor, with nonspecific symptoms. Surgery with clear margins remains the treatment of choice. Prognosis depends on the extent of tumor at presentation, resection margins, and grade of tumor.

Piloleiomyosarcoma in Seven Ferrets

2001 ◽  
Vol 38 (6) ◽  
pp. 710-711 ◽  
Author(s):  
B. H. Rickman ◽  
L. E. Craig ◽  
M. H. Goldschmidt
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Immunohistochemical Staining ◽  
Smooth Muscle Actin ◽  
Surgical Excision ◽  
Muscle Actin ◽  
Mustela Putorius ◽  
Nuclear Pleomorphism ◽  
Complete Surgical Excision

In each of seven ferrets ( Mustela putorius furo) with leiomyosarcoma, a single dermal mass was identified and biopsied. Each mass consisted of a well-demarcated but nonencapsulated proliferation of large spindle- to strap-shaped cells arranged in interwoven bundles. The cells resembled the smooth muscle cells of the adjacent arrector pili muscles, but with marked nuclear pleomorphism. Immunohistochemical staining for smooth muscle actin, desmin, and vimentin was positive and staining for myoglobin and cytokeratin was negative. Follow-up on three of the ferrets indicates that the prognosis is good following complete surgical excision.

scholarly journals Neoplasia sólida pseudopapilar del páncreas. Reporte de un caso

2020 ◽  
Vol 50 (3) ◽  
Author(s):  
Ignacio Maldonado Schoijet ◽  
Javiera Vásquez Poblete ◽  
Sergio Álvarez Diaz ◽  
Javier González Moscoso
Keyword(s):  
Pancreatic Tumor ◽  
Abdominal Ultrasound ◽  
Good Prognosis ◽  
Cystic Mass ◽  
The Body ◽  
Pancreatic Tumors ◽  
Imaging Features ◽  
Solid Pseudopapillary Neoplasm ◽  
Resonance Imaging ◽  
The One

Background. Solid pseudopapillary neoplasm of the pancreas is an uncommon exocrine pancreatic tumor of epithelial origin, which represents only 1% to 2% of all pancreatic tumors and mainly affects young women. Objective. To describe clinical and imaging features of these rare entity in a symptomatic young woman. Case report. 41-year-old female patient, without morbid history, consulted for intermittent epigastralgia of one-month evolution. Abdominal ultrasound and magnetic resonance imaging demonstrated the presence of a solid-cystic mass of neoplastic appearance in the body-tail of the pancreas. The case was presented to the institutional hepato-biliary committee where surgical resection was decided. Discussion. Although solid pseudopapillary neoplasm of the pancreas are very uncommon pancreatic tumors, it is necessary to keep them within the differential diagnosis on the one hand due to their low but existing malignant potential and on the other hand due to their good prognosis with surgical treatment.

scholarly journals Spinal osteoid osteoma: Surgical resection and review of literature

2020 ◽  
Vol 11 ◽  
pp. 308
Author(s):  
Abhinandan Reddy Mallepally ◽  
Rajat Mahajan ◽  
Sandesh Pacha ◽  
Tarush Rustagi ◽  
Nandan Marathe ◽  
...  
Keyword(s):  
Surgical Resection ◽  
Osteoid Osteoma ◽  
Surgical Excision ◽  
Presenting Symptoms ◽  
Complete Surgical Excision ◽  
Rare Benign Tumor ◽  
The Common ◽  
Optimal Approach ◽  
Posterior Elements

Background: Osteoid osteoma (OO) is a rare benign tumor of the spine that involves the posterior elements with 75% tumors involving the neural arch. The common presenting symptoms include back pain, deformity like scoliosis, and rarely radiculopathy. Methods: From 2011 to 2017, we evaluated cases of OO managed by posterior surgical resection while also reviewing the appropriate literature. Results: We assessed five patients (three males and two females) averaging 36.60 years of age diagnosed with spinal OOs. Two involved the lumbar posterior elements, two were thoracic, and one was in the C3 lateral mass. All patients underwent histopathological confirmation of OO. They were managed by posterior surgical resection with/without stabilization. No lesions recurred over the minimum follow-up period of 24 months. Conclusion: Surgical excision is the optimal treatment modality for treating spinal OOs. The five patients in this study demonstrated good functional outcomes without recurrences. Further, the literature confirms that the optimal approach to these tumors is complete surgical excision with/without radiofrequency ablation.

scholarly journals Basal Cell Carcinoma Surgery: Simple Undermining Approach in Two Patients with Different Tumour Locations

2017 ◽  
Vol 5 (4) ◽  
pp. 506-510
Author(s):  
Georgi Tchernev ◽  
Cristiana Voicu ◽  
Mara Mihai ◽  
Tiberiu Tebeica ◽  
Nely Koleva ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Surgical Excision ◽  
Good Prognosis ◽  
Complete Surgical Excision ◽  
Skin Cancers ◽  
Human Malignancy ◽  
Hedgehog Signalling Pathway ◽  
Cure Rates

Basal cell carcinoma (BCC) is the most common human malignancy, accounting for the majority of all non-melanoma skin cancers (NMSC). In the past several decades the worldwide incidence of BCC has constantly been increasing. Even though it is a slow growing tumour that, left untreated, rarely metastasizes, it has a distinctive invasive growth pattern, posing a considerable risk for local invasion and destruction of underlying tissues, such as muscle, cartilage, bone or vital structures. Advanced BCCs include such locally invasive or metastatic tumours. Complete surgical excision is the standard therapy for most uncomplicated BCC cases with good prognosis and cure rates. Treatment of advanced forms of BCCs poses significant therapeutic challenges, most often requiring complicated surgery, radiotherapy, and/or targeted therapies directed towards the sonic hedgehog signalling pathway (SHH). We present two cases of large BCCs located on the scalp and posterior thorax, which underwent surgical excision with clear margins, followed by reconstruction of the defect after extensive undermining of the skin.

scholarly journals A Rare Presentation of Schwannoma as a Purely-Cystic Superficial-Intermuscular Extra-Spinal Swelling over Upper Back.

2020 ◽  
Author(s):  
Srinjoy Saha
Keyword(s):  
Surgical Excision ◽  
Thoracic Vertebrae ◽  
Rare Presentation ◽  
Complete Surgical Excision ◽  
Rare Tumours ◽  
S 100 ◽  
One Year ◽  
Atypical Presentations ◽  
Upper Thoracic

Abstract Schwannomas are rare tumours arising from peripheral nerve sheath. Here, a 44-year-old lady came to our clinic with an asymptomatic progressively-enlarging swelling over her upper back. It was fluctuant, with an absence of pain and tenderness. MRI showed a benign, purely-cystic, superficial-intermuscular, extra-spinal swelling nearby upper thoracic vertebrae. Complete surgical excision proceeded smoothly through a well-defined plane between the swelling and the muscles. It was not attached to any identifiable nerve. A 6.5x5.0x2.5 cm ovoid lesion with a glistening whitish-grey capsule was excised and wound reconstructed in layers. Histopathology showed hypercellular areas with nuclear palisading or oval-shaped Verocay bodies. Only S-100 tested positive amongst the five-antigen immunohistochemistry, thus establishing the diagnosis of a schwannoma. Postoperatively, a one-year follow-up period was uneventful. Schwannomas can surprise clinicians by arising anywhere and with atypical presentations. It needs to be in the differential diagnoses of any asymptomatic slowly-growing lesion.

scholarly journals Nasolabial cyst: case report and review of management options

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Abdulhakeem Almutairi ◽  
Abeer Alaglan ◽  
Mazyad Alenezi ◽  
Sultan Alanazy ◽  
Osama Al-Wutayd
Keyword(s):  
Soft Tissue ◽  
Nasal Obstruction ◽  
Surgical Excision ◽  
Mass Effect ◽  
Treatment Modalities ◽  
Open Approach ◽  
Management Options ◽  
Case Presentation ◽  
Complete Surgical Excision

Abstract Background Nasolabial cysts are rare, non-odontogenic, soft-tissue cysts that develop between the upper lip and nasal vestibule with an overall incidence of 0.7% out of all maxillofacial cysts. The predominant presentation of a nasolabial cyst is a painless localized swelling with varying degrees of nasal obstruction. Several treatment modalities have described in the management of the nasolabial cyst. In this paper, we present a case of a nasolabial cyst in a 44 years old man with discussions of the treatment modalities in the lights of the literature. Case presentation We present a case of a nasolabial cyst in a 44-year-old man that slowly increased in size through a period of 3 years, with associated mild pain and nasal obstruction. It had caused a mass effect upon the maxilla, resulting in scalloping. The cyst was excised entirely with no evidence of recurrence at the two months follow up. Conclusions The nasolabial cyst is a rare soft-tissue cyst. Complete surgical excision using an open approach performed to our case, which considered with the complete endoscopic removal of the best treatment for the nasolabial cysts with a rare recurrence rate.

scholarly journals Clinicopathological characteristics and treatment outcomes of adult

2013 ◽  
Vol 6 (1) ◽  
pp. 42 ◽  
Author(s):  
Serkan Keskin ◽  
Mert Basaran ◽  
Isin Kilicaslan ◽  
Murat Tunc ◽  
Sevil Bavbek
Keyword(s):  
Surgical Excision ◽  
Local Relapse ◽  
Clinicopathological Characteristics ◽  
Survival Times ◽  
Single Institution ◽  
Retroperitoneal Lymphadenectomy ◽  
Distant Relapse ◽  
Group I ◽  
Retroperitoneal Node

Introduction: We report our experience with 8 consecutive adults treated for paratesticular rhabdomyosarcoma (RMS) at a single institution between 2000 and 2010.Methods: After primary surgical excision, 7 patients were classified into group I according to the Intergroup Rhabdomyosarcoma Study Group (IRSG) Postsurgical Grouping Classification, and 1 patient into group IIB. Retroperitoneal node dissection was not a required staging procedure. Adjuvant chemotherapy was administered to 7 of the 8 patients. No additional radiotherapy was administered.Results: The median age at diagnosis was 24 years (range: 18-60). Embryonal histology was the most common (75%) subtype. During follow-up, 3 patients experienced local relapse and 5 distant relapse. The median progression-free and overall survival times were 17.0 ± 9.9 months (range: 5-31) and 27.3 ± 1.3 months (range: 16-58), respectively.Conclusion: Paratesticular RMS is an uncommon malignancy inadults. We confirm that patients with localized paratesticular RMS may have different prognoses. Retroperitoneal lymphadenectomy can be avoided as a treatment for paratesticular RMS after radical inguinal orchiectomy.

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