Prevalence of depression, anxiety and stress in china during COVID-19 pandemic: A systematic review with meta-analysis

Background The novel coronavirus disease which is believed to have initially originated in Wuhan city of China at the end of 2019 was declared as pandemic by March 2020 by WHO. This pandemic significantly impacted the mental health of communities around the globe. This project draws data from available research to quantify COVID-19 mental health issues and its prevalence in China during the early period of the COVID-19 crisis. It is believed that this pooling of data will give fair estimate of the effects of the COVID-19 pandemic on mental health. Methods We conducted this study in accordance with PRISMA guidelines 2009. The protocol for this review is registered and published in PROSPERO (CRD42020182893). The databases used were Pubmed, Medline, Google scholar and Scopus. The studies were extracted according to pre-defined eligibility criteria and risk of bias assessment was conducted. The Meta-analysis was done using OpenMeta [analyst]. Results Total of 62382 participants in nineteen studies fulfilled the eligibility criteria. Stress was the most prevalent (48.1%) mental health consequence of Covid-19 pandemic, followed by depression (26.9%) and anxiety (21.8%). After performing subgroup analysis, prevalence of depression and anxiety in both females and frontline health care workers were high as compared to the prevalence in general Chinese population. Conclusion The prevalence of depression and anxiety is moderately high whereas pooled prevalence of stress was found to be very high in Chinese people during this Covid-19 crisis.

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Mental Health of Pregnant Women during Covid-19: A Systematic Review Study

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2021/v33i2131145 ◽

2021 ◽

pp. 156-174

Author(s):

God’s Favour Adediran ◽

Derma Dupuis ◽

Kasinda Fritz ◽

Olebogeng Leso ◽

Emeka Ike ◽

...

Keyword(s):

Mental Health ◽

Systematic Review ◽

Pregnant Women ◽

North American ◽

Geographical Location ◽

Depression And Anxiety ◽

Health Issues ◽

The North ◽

Prevalence Of Depression ◽

Novel Coronavirus

Background: The novel coronavirus (COVID-19) pandemic has created avenues for physical and mental stress on individuals worldwide. Pregnant women especially, with the onset of COVID-19 have been challenged greatly by an array of disorders, all with varying cognitive, emotional, and behavioral responses. The aim of our research is to conduct a review of the different mental health issues experienced by pregnant women in various geographical locations and analyze the prevalence of specific mental issues. Materials and Methods: A mixed-methods systematic review was conducted. Databases PubMed, Google Scholar, BioMed Central, CrossRef and British Medical Journal were thoroughly examined by the authors for the purpose of locating the relevant articles as per specific geographical location. Results: From the applicable studies identified, twenty-eight (28) were selected for review. As per the North American studies, levels of depression and anxiety in pregnant women at and around the time of the pandemic ranged from 33.2 to 70%. This differs in European countries where there were levels of 14.0 to 60%. Prevalence of stress among pregnant women in Asia was 32.7% while 17% of North American women reported the same. In the studies of Australia and South America, the prevalence of anxiety ranged 6% to 13.9% while studies in Africa reported severe and extremely stress, 7.2% (n=33) and 64% (n=29) respectively. Conclusion: The prevalence of depression and anxiety among pregnant women was shown to be relatively high in all regions as per the COVID-19 pandemic, owing to many factors. Based on the studies analyzed, adequate support, resources and better healthcare systems are imperative for ensuring that depression and anxiety levels be reduced among this demographic.

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Psychological distress among healthcare providers during COVID-19 in Asia: Systematic review and meta-analysis

PLoS ONE ◽

10.1371/journal.pone.0257983 ◽

2021 ◽

Vol 16 (10) ◽

pp. e0257983

Author(s):

Siew Mooi Ching ◽

Kar Yean Ng ◽

Kai Wei Lee ◽

Anne Yee ◽

Poh Ying Lim ◽

...

Keyword(s):

Meta Analysis ◽

Healthcare Providers ◽

Random Effects Model ◽

Depression And Anxiety ◽

Cross Sectional ◽

Funnel Plot ◽

Health And Wellbeing ◽

Pooled Prevalence ◽

Increased Risk ◽

Prevalence Of Depression

Introduction COVID-19 pandemic is having a devastating effect on the mental health and wellbeing of healthcare providers (HCPs) globally. This review is aimed at determining the prevalence of depression, anxiety, stress, fear, burnout and resilience and its associated factors among HCPs in Asia during the COVID-19 pandemic. Material and methods We performed literature search using 4 databases from Medline, Cinahl, PubMed and Scopus from inception up to March 15, 2021 and selected relevant cross-sectional studies. Publication bias was assessed using funnel plot. Random effects model was used to estimate the pooled prevalence while risk factors were reported in odds ratio (OR) with 95% CI. Results We included 148 studies with 159,194 HCPs and the pooled prevalence for depression was 37.5% (95%CI: 33.8–41.3), anxiety 39.7(95%CI: 34.3–45.1), stress 36.4% (95%CI: 23.2–49.7), fear 71.3% (95%CI: 54.6–88.0), burnout 68.3% (95%CI: 54.0–82.5), and low resilience was 16.1% (95%CI: 12.8–19.4), respectively. The heterogeneity was high (I2>99.4%). Meta-analysis reported that both females (OR = 1.48; 95% CI = 1.30–1.68) and nurses (OR = 1.21; 95%CI = 1.02–1.45) were at increased risk of having depression and anxiety [(Female: OR = 1.66; 95% CI = 1.49–1.85), (Nurse: OR = 1.36; 95%CI = 1.16–1.58)]. Females were at increased risk of getting stress (OR = 1.59; 95%CI = 1.28–1.97). Conclusion In conclusion, one third of HCPs suffered from depression, anxiety and stress and more than two third of HCPs suffered from fear and burnout during the COVID-19 pandemic in Asia.

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Olfactory and gustatory dysfunction in 2019 novel coronavirus: An updated systematic review and meta-analysis

10.21203/rs.3.rs-44648/v1 ◽

2020 ◽

Author(s):

Marzieh Esmaeili ◽

Fatemeh Abdi ◽

Gita Shafiee ◽

Hadis Rastad ◽

Hamid Asayesh ◽

...

Keyword(s):

Systematic Review ◽

English Language ◽

Meta Analysis ◽

Random Effect ◽

Eligibility Criteria ◽

Language Studies ◽

Pooled Prevalence ◽

Comprehensive Search ◽

Novel Coronavirus

Abstract BackgroundEvidence showed that partial or complete loss of smell and taste might be a possible primary symptom of the 2019 novel coronavirus (COVID-19). This study aimed to systematically review and pool all available evidence on the olfactory and gustatory dysfunction in COVID-19 patients. MethodsIn this systematic review, a comprehensive search was carried out systematically through e-databases including PubMed, EMBASE, Scopus, and Web of Science (WoS); that was limited to English-language studies published from 2019 up to 6th May 2020. Afterward, all studies reported the taste and smell dysfunction in the COVID-19 patients were included. The quality of the studies was assessed by the Mixed Methods Appraisal Tool (MMAT). The pooled prevalence of olfactory and gustatory dysfunction was estimated using the random effects meta-analysis method.ResultsAmong 28 eligible included studies in this systematic review, finally, 22 studies met the eligibility criteria and were included in the meta-analysis. According to the random effect meta-analysis, the global pooled prevalence (95% confidence interval) of any olfactory dysfunction, anosmia, and hyposmia was 55% (40%-70%), 40% (22%-57%), and 40% (20%-61%) respectively. The pooled estimated prevalence of any gustatory dysfunction, ageusia, and dysgeusia was 41% (23%-59%), 31% (3%-59%), and 34% (19%-48%) respectively. ConclusionOlfactory and gustatory dysfunction is prevalent among COVID-19 patients. Therefore, olfactory and gustatory dysfunction seems to be part of important symptoms and notify for the diagnosis of COVID-19, especially in the early phase of the infection.

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The Psychological Impact of COVID-19 Pandemic on Health Care Workers: A Systematic Review and Meta-Analysis

Frontiers in Psychology ◽

10.3389/fpsyg.2021.626547 ◽

2021 ◽

Vol 12 ◽

Author(s):

Ping Sun ◽

Manli Wang ◽

Tingting Song ◽

Yan Wu ◽

Jinglu Luo ◽

...

Keyword(s):

Health Care ◽

Health Care Workers ◽

Meta Analysis ◽

Psychological Impact ◽

Frontline Workers ◽

General Mental Health ◽

Pooled Prevalence ◽

Care Workers ◽

Prevalence Of Depression ◽

Great Stress

Objective: The COVID-19 epidemic has generated great stress throughout healthcare workers (HCWs). The situation of HCWs should be fully and timely understood. The aim of this meta-analysis is to determine the psychological impact of COVID-19 pandemic on health care workers.Method: We searched the original literatures published from 1 Nov 2019 to 20 Sep 2020 in electronic databases of PUBMED, EMBASE and WEB OF SCIENCE. Forty-seven studies were included in the meta-analysis with a combined total of 81,277 participants.Results: The pooled prevalence of anxiety is 37% (95% CI 0.31–0.42, I2 = 99.9%) from 44 studies. Depression is estimated in 39 studies, and the pooled prevalence of depression is 36% (95% CI 0.31–0.41, I2 = 99.6%). There are 10 studies reported the prevalence of insomnia, and the overall prevalence of insomnia is 32% (95% CI 0.23–0.42, I2 = 99.5%). The subgroup analysis showed a higher incidence of anxiety and depression among women and the frontline HCWs compared to men and non-frontline HCWs respectively.Conclusions: The COVID-19 pandemic has caused heavy psychological impact among healthcare professionals especially women and frontline workers. Timely psychological counseling and intervention ought to be implemented for HCWs in order to alleviate their anxiety and improve their general mental health.

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Meta-Analysis of Prevalence of Depression in Dental Students during COVID-19 Pandemic

Medicina ◽

10.3390/medicina57111278 ◽

2021 ◽

Vol 57 (11) ◽

pp. 1278

Author(s):

Javier Santabárbara ◽

Naiara Ozamiz-Etxebarria ◽

Nahia Idoiaga ◽

Beatriz Olaya ◽

Juan Bueno-Novitol

Keyword(s):

Mental Health ◽

College Students ◽

Response Rate ◽

Negative Impact ◽

Meta Analysis ◽

Dental Students ◽

Random Effects Models ◽

Health And Wellbeing ◽

Pooled Prevalence ◽

Prevalence Of Depression

Background and Objectives: The COVID-19 pandemic has a negative impact on the mental health of the population in general, and in college students in particular. Dental students have seen their teaching altered and their clinical practice reduced. This study was aimed at conducting a systematic review and meta-analysis of studies reporting levels of depression among dental students during the COVID-19 and estimating the pooled prevalence of depression. Materials and Methods: Medline via PubMed and other databases were searched for studies on the prevalence of depression in dental undergraduates, published from 1 December 2019 to 1 September 2021. The pooled proportions of depression were calculated with random effects models. Results: We identified 13 studies from 9 countries. The pooled prevalence of depression in dental students was 37% (95% CI: 26–49%) with no variation due to gender, response rate or methodological quality. We only found a significantly higher prevalence of depression in studies from Asia compared to Europe and America. Conclusions: Our results suggest that dental students are suffering from higher levels of depression compared with the general population or other college students during the COVID-19 pandemic, with differences across regions. Measures to improve mental health and wellbeing of dental students during the pandemic are needed.

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Prevalence of common mental health issues among migrant workers: A systematic review and meta-analysis

PLoS ONE ◽

10.1371/journal.pone.0260221 ◽

2021 ◽

Vol 16 (12) ◽

pp. e0260221

Author(s):

Siti Idayu Hasan ◽

Anne Yee ◽

Ariyani Rinaldi ◽

Adlina Aisya Azham ◽

Farizah Mohd Hairi ◽

...

Keyword(s):

Mental Health ◽

Social Support ◽

Systematic Review ◽

Migrant Workers ◽

Meta Analysis ◽

Grey Literature ◽

Well Being ◽

Qualitative Assessment ◽

Depression And Anxiety ◽

Prevalence Of Depression

Previous literature has shown that migrant workers manifested higher common mental issues (especially depressive symptom) compared to local workers due to stressors such as financial constraint and lack of access to healthcare. The aim of this systematic review and meta-analysis is to summarize the current body of evidence for the prevalence of depression and anxiety among migrant workers as well as exploring the risk factors and the availability of social support for migrant workers. Seven electronic databases, grey literature and Google Scholar were searched for studies from 2015 to 2021 related to mental health, social support and migrant workers. Study quality was assessed using the Newcastle Ottawa Scale and the Joanna Briggs Institute Qualitative Assessment and Review Instrument (JBI-QARI). Study heterogeneity was evaluated using I2 statistics. Random effects meta-analysis results were presented given heterogeneity among studies. The search returned 27 articles and only seven studies were included in meta-analysis, involving 44 365 migrant workers in 17 different countries. The overall prevalence of depression and anxiety among migrant workers was 38.99% (95% CI = 0.27, 0.51) and 27.31% (95% CI = 0.06, 0.58), respectively. Factors such as age, biological (health issue, family history of psychiatric disorder), individual (poor coping skills), occupational (workplace psychosocial stressors, poor working condition, salary and benefits issue, abuse), environmental (limited access towards healthcare, duration of residence, living condition) and social factor (limited social support) were associated with a mental health outcome in migrant workers. The availability of social support for migrant workers was mainly concentrated in emotional type of support. A high prevalence of depression and anxiety was found among migrant workers across the globe. This finding warrants a collective effort by different parties in providing assistance for migrant workers to promote their mental well-being.

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A Longitudinal Study on the Mental Health of College Students in Jinan During the Peak Stage of the COVID-19 Epidemic and the Society Reopening

Biomedicine Hub ◽

10.1159/000519586 ◽

2021 ◽

pp. 102-110

Author(s):

Xiaolei Zheng ◽

Yuji Guo ◽

Wen Ma ◽

Hui Yang ◽

Liyan Luo ◽

...

Keyword(s):

Mental Health ◽

College Students ◽

Severe Depression ◽

Severity Index ◽

Depression And Anxiety ◽

Health Issues ◽

Mental Health Issues ◽

Prevalence Of Depression ◽

Patient Health ◽

Peak Versus

Introduction: COVID-19, a continuously emerging human-to-human infectious disease, has exerted a significant impact on the mental health of college students. However, little is known regarding the variations in the mental health issues experienced by college students during the peak versus reopening stages of the COVID-19 epidemic in China. Methods: To assess these issues, an online longitudinal survey was conducted via a WeChat applet. Undergraduates (n = 300) were recruited from 26 universities throughout Jinan in February 2020 (T1 – the epidemic peak stage) and in January 2021 (T2 – the society reopening stage). Their mental status was determined using the Patient Health Questionnaire-9, the Generalized Anxiety Disorder-7 item, and the Insomnia Severity Index. Results: Of the original 300 college students recruited for this survey, 294 responses at T1 and 285 at T2 were analyzed. Compared with responses obtained at T1, college students at T2 showed a greater prevalence of depression (65.3 vs. 51.0%; p = 0.001) and anxiety (47.7 vs. 38.1%, p = 0.019), and experienced more severe depression (p < 0.001) and anxiety (p < 0.001). Both males (p = 0.03) and females (p < 0.01) showed higher levels of depression at T2 versus T1, while no differences were obtained with regard to anxiety and insomnia. At T1, Grade 4 students showed greater levels of depression (p = 0.005) and anxiety (p = 0.008) than that of Grade 1 students. While at T2, only greater levels of depression (p = 0.004) were present when compared with that of Grade 1 students. Additionally, Grade 4 college students demonstrated a greater prevalence of depression at T2 versus T1 (p = 0.03), but no statistically differences were present for anxiety and insomnia. No statistically significant differences were obtained among the 4 grades of college students for insomnia at either the T1 or T2. Conclusion: With progression of the COVID-19 epidemic, college students showed increasing levels of depression and anxiety, with Grade 4 college students being most seriously affected. It is imperative that intervention strategies be implemented to mitigate against these mental health issues resulting from the COVID-19 epidemic.

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A hidden pandemic? An umbrella review of global evidence on mental health in the time of COVID-19

10.31234/osf.io/bzpvw ◽

2022 ◽

Author(s):

Marlee Bower ◽

Scarlett Smout ◽

Amarina Donohoe-Bales ◽

Lily Teesson ◽

Eleisha Lauria ◽

...

Keyword(s):

Mental Health ◽

General Population ◽

Health Outcomes ◽

Systematic Reviews ◽

Meta Analysis ◽

Mental Health Outcomes ◽

Eligibility Criteria ◽

Pooled Prevalence ◽

Meta Review ◽

Meta Analyses

Introduction: Vast available international evidence has investigated the mental health impacts of the COVID-19 pandemic. This review aims to synthesise evidence, identifying populations and characteristics associated with poor mental health.Methods: A meta-review of pooled prevalence of anxiety and depression, with subgroup analyses for the general population, healthcare workers (HCW) and COVID-19 patients; and a meta-synthesis of systematic reviews to collate evidence on associated factors and further mental disorders. Databases searched included Scopus, Embase, PsycINFO, and MEDLINE dated to May 2021. Eligibility criteria included systematic reviews and/or meta-analyses, published post-November 2019, reporting data in English on mental health outcomes during the pandemic.Results: Eighty-one systematic reviews were included, 51 of which incorporated meta-analysis. Meta-review overall anxiety prevalence was 29% (95%CI: 27–31%, I2: 99.83%), with subgroup prevalence as 35% (95%CI: 23–47%, I2: 97.4%) in COVID-19 patients, 29% in HCW (95%CI: 25– 32, I2: 99.8%) and 28% in the general population (95%CI: 25–31%, I2: 99.9%). Meta-review overall depression prevalence was 28% (95%CI: 26–30%, I2: 99.7), with subgroup prevalence as 30% (95%CI: 7–60%, I2: 99.8%) in COVID-19 patients, 28% (95%CI: 25–31%, I2: 99.7%) in HCW and 27% (95%CI: 25–30, I2: 99.8%) in the general population. Meta-synthesis found many experienced psychological distress and PTSD/PTSS during COVID-19, but pooled prevalence ranged substantially. Fear of, proximity to, or confirmed COVID-19 infection; undergoing quarantine; and COVID-19-related news exposure were associated with adverse mental health outcomes. Amongst other factors, people who are younger, female, LGBTIQ, pregnant, parents or experiencing low social support, financial issues or socio-economic disadvantage, tended to have poorer mental health during the pandemic period.Conclusions: Despite high volumes of reviews, the diversity of findings and dearth of longitudinal studies within reviews means clear links between COVID-19 and mental health are not available, although existing evidence indicates probable associations.

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A meta-analysis examining the association between maternal perfectionism and perinatal depression and anxiety

10.31234/osf.io/2x8jr ◽

2021 ◽

Author(s):

Clare Evans ◽

Jana Kreppner ◽

Peter J Lawrence

Keyword(s):

Mental Health ◽

Perinatal Depression ◽

Mental Health Problems ◽

Meta Analysis ◽

Perinatal Period ◽

Perinatal Mental Health ◽

Depression And Anxiety ◽

Eligibility Criteria ◽

Prior Review ◽

Mental Health Difficulties

Background: Perfectionism is an important feature of adult psychopathology. In the absence of a prior review of the role of perfectionism in perinatal psychopathology, we aimed to ascertain whether perfectionism was associated with symptoms of maternal perinatal depression and anxiety. Method: We followed PRISMA guidance (PROSPERO: 42019143369 ), estimated weighted effect sizes and tested possible moderators: timing (pre or post- natal), scales used to measure constructs, infant gender, temperament and age; and rated study quality. Results: 14 studies met eligibility criteria. Perfectionism as a whole, and the perfectionistic concerns dimension, were moderately correlated with common maternal perinatal mental health difficulties r= 0.32 (95% Confidence Interval = 0.23 to 0.41). In sub-group analyses, perfectionistic concerns were associated with depression (r=.35, 95% CI = 0.26 – 0.43). We found no evidence of significant moderation of associations. Limitations: Included studies had methodological and conceptual limitations. Studies inconsistently examined both perfectionistic concerns and strivings, nor anxiety as well as depression. Conclusions: Perfectionism, especially perfectionistic concerns, appears to be an important feature of common maternal perinatal mental health problems. While further research is warranted, screening and identification of perfectionism in the perinatal period may help focus resources for intervention, reducing the prevalence of perinatal mental health difficulties.

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Prevalence of depression among school going adolescents in India: a systematic review and meta-analysis of cross-sectional studies

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20210248 ◽

2021 ◽

Vol 8 (2) ◽

pp. 833

Author(s):

Prashanthi Kamath ◽

Sushma Marita Dsouza ◽

Subhransu Mahapatra ◽

Sruthi Jayakumar

Keyword(s):

Mental Health ◽

High School ◽

Systematic Review ◽

Meta Analysis ◽

Random Effect ◽

Cochrane Library ◽

Cross Sectional ◽

School Based ◽

Pooled Prevalence ◽

Prevalence Of Depression

The objective of this systematic review was to estimate the pooled prevalence of depression among schoolgoing adolescents in India by using Beck’s Depression Inventory (BDI 1 or BDI 2). A systematic literature search was conducted in PubMed, Ovid MEDLINE, Ovid EMBASE, CINAHL, Cochrane Library, PsycINFO and Google Scholar to identify cross-sectional school-based studies published during 1990-2020. Studies with pre-identified mental illness were excluded. Heterogeneity between studies were examined and estimates were pooled using a random-effects model. Subgroup and sensitivity analysis were performed. Publication bias was evaluated using funnel plot and Egger’s test. We included 13 studies in the meta-analysis. The random effect meta-analysis revealed that the pooled prevalence of depression among school going adolescents was 53% (95% CI: 41% - 65%). By gender, the prevalence was 50% (95 % CI: 38%–62%) in males and 57% (95% CI: 46% - 69%) in females. The subgroup analysis revealed that the pooled prevalence increased with the education levels (High school: 42%; High school and pre-university: 55%; and Pre-university: 67%). In this review we found that more than half of the school going adolescents in India suffered from depression that ranged from mild to severe. These results draw attention to re-look at the mental health policy and newer public health approaches to address depression. Further, strengthening school-based mental health services, along with the community and center-based care is crucial to prevent and effective management of depression among adolescents.

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