The BDNF Val66Met Polymorphism, Regular Exercise, and Cognition: A Systematic Review

2020 ◽  
Vol 42 (8) ◽  
pp. 660-673
Author(s):  
Tingting Liu ◽  
Hongjin Li ◽  
Joseph P. Colton ◽  
Song Ge ◽  
Changwei Li
Keyword(s):  
English Language ◽  
Research Evidence ◽  
Human Subjects ◽  
Regular Exercise ◽  
Journal Articles ◽  
Information Processing Speed ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism ◽  
Global Cognition ◽  
The Relationship

The purpose of this study was to synthesize research evidence from studies on the relationships among the BDNF Val66Met polymorphism, regular exercise, and cognition in human subjects. PubMed, CINAHL, and Web of Science were searched systematically. Search limiters applied in these databases included humans, English language, time limits from 2009 to 2019, and peer-reviewed journal articles. Eight studies were included in the current review. While there was some evidence to tentatively suggest that greater levels of exercise were associated with certain forms of memory in Val/Val homozygotes than Met carriers, more research is needed to corroborate these findings. Regarding attention/information processing speed, executive function as well as global cognition, the evidence is either inconsistent or sparse and does not allow for tentative conclusions. Compelling evidence from high-quality clinical trials is needed to re-examine the relationship between the BDNF Val66Met polymorphism, exercise, and cognition.

scholarly journals The BDNF Val66Met polymorphism moderates the relationship between cognitive reserve and executive function

2015 ◽  
Vol 5 (6) ◽  
pp. e590-e590 ◽  
Author(s):  
D D Ward ◽  
M J Summers ◽  
N L Saunders ◽  
K Ritchie ◽  
J J Summers ◽  
...  
Keyword(s):  
Executive Function ◽  
Cognitive Reserve ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism ◽  
The Relationship

scholarly journals DEMOCRACY AND DEMOCRATIZATION IN THE MUSLIM WORLD: AN EVALUATION OF SOME IMPORTANT WORKS ON DEMOCRATIZATION IN SOUTH/SOUTHEAST ASIA

2017 ◽  
Vol 2 (01) ◽  
pp. 79
Author(s):  
Tauseef Ahmad Parray
Keyword(s):  
Southeast Asia ◽  
South Asia ◽  
Central Asia ◽  
English Language ◽  
East Asian ◽  
Review Of The Literature ◽  
Journal Articles ◽  
Empirical Level ◽  
Comparative Methodology ◽  
The Relationship

Is Islam compatible with democratization in the context of Asian cultures? To address this important issue, a series of books have been published in the English language from 1990s (and especially from 2000s). Most of these books deal with the relationship between Islam, Muslims, and democratization with a sub-region in Asia: South Asia, Southeast Asia, and Central Asia. While others deal with same issues with a focus on the future, very few deal with the relationship between Islam, Muslims, and democratization in the context of Asian cultures from the perspectives of theory and empirical country studies from all three Asian regions. In this backdrop, this essay—by making an assessment and review of the literature, produced in the last decade, on this theme—focuses on the compatibility paradigm in South and South East Asian Muslim societies at the empirical level, with a focus on Pakistan, Bangladesh, Malaysia, and Indonesia. To achieve this objective, the essay follows the analytical and comparative methodology, and evaluates these four important books: Zoya Hasan (2007); Shiping Hua (2009); Mirjam Künkler and Alfred Stepan (2013); and John Esposito, Tamara Sonn, and John Voll (2016). A due support is taken from other related works (books and journal articles) as well in substantiating, supporting, and strengthening the argument(s) put forth in this essay.

scholarly journals Systematic Quantitative Literature Review on Criminological Theories in Asia

2017 ◽  
Author(s):  
Masahiro Suzuki ◽  
Chen-Fu Pai ◽  
Md. Jahirul Islam
Keyword(s):  
Social Learning ◽  
Literature Review ◽  
English Language ◽  
Empirical Work ◽  
Routine Activity ◽  
Journal Articles ◽  
English Language Journal ◽  
Asian Context ◽  
Criminological Theories ◽  
The Relationship

Empirical work on criminological theories in Asia has been increasing. However, few comprehensive and systematic reviews on the application of criminological theories in Asia have been conducted. Using a systematic quantitative literature review method on peer-reviewed English-language journal articles, we aim to provide an overview of the use of five major criminological theories in Asia: (1) strain; (2) social learning; (3) control; (4) routine activity; and (5) developmental and life-course. In particular, we address the following four questions: (1) how often are these theories tested in which region of Asia?; (2) what methodology is used to test these theories?; (3) to what extent are these theories supported in the Asian context?; and (4) what cultural uniqueness in the Asian context is taken into account in testing these theories, and what role and effect do they play in analysis and outcome? Findings indicate that the relationship between these theories and the Asian regions is skewed; many studies do not employ rigorous methodologies; these theories are either fully or partially supported in the Asian context; and only a few studies have analyzed the cultural uniqueness of the Asian context, and no effect of cultural uniqueness of the Asian context was found. Research implications for developing criminology in Asia are discussed.

364. The BDNF Val66Met Polymorphism Moderates the Relationship between PTSD and Fear Extinction Learning

2017 ◽  
Vol 81 (10) ◽  
pp. S149 ◽  
Author(s):  
Kim Felmingham ◽  
Daniel Zuj ◽  
Ken Chia Ming Hsu ◽  
Emma Nicholson ◽  
Matthew Palmer ◽  
...  
Keyword(s):  
Fear Extinction ◽  
Extinction Learning ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism ◽  
The Relationship

BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia

2010 ◽  
Vol 25 (6) ◽  
pp. 311-313 ◽  
Author(s):  
G. Spalletta ◽  
D.W. Morris ◽  
F. Angelucci ◽  
I.A. Rubino ◽  
I. Spoletini ◽  
...  
Keyword(s):  
Aggressive Behavior ◽  
Neurotrophic Factor ◽  
Aggressive Behaviour ◽  
Brain Derived Neurotrophic Factor ◽  
Gene Variants ◽  
Bdnf Gene ◽  
Val66met Polymorphism ◽  
Schizophrenic Patients ◽  
Bdnf Val66met Polymorphism ◽  
The Relationship

AbstractBrain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.

scholarly journals Non-Motor Symptoms after One Week of High Cadence Cycling in Parkinson’s Disease

2019 ◽  
Vol 16 (12) ◽  
pp. 2104 ◽  
Author(s):  
Sara A. Harper ◽  
Bryan T. Dowdell ◽  
Jin Hyun Kim ◽  
Brandon S. Pollock ◽  
Angela L. Ridgel
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Depression Symptoms ◽  
Motor Cognition ◽  
Val66met Polymorphism ◽  
Main Effect ◽  
Bdnf Val66met Polymorphism ◽  
Global Cognition ◽  
Non Motor Symptoms ◽  
High Cadence

The objective was to investigate if high cadence cycling altered non-motor cognition and depression symptoms in individuals with Parkinson’s disease (PD) and whether exercise responses were influenced by brain-derived neurotrophic factor (BDNF) Val66Met polymorphism. Individuals with idiopathic PD who were ≥50 years old and free of surgical procedures for PD were recruited. Participants were assigned to either a cycling (n = 20) or control (n = 15) group. The cycling group completed three sessions of high cadence cycling on a custom motorized stationary ergometer. The primary outcome was cognition (attention, executive function, and emotion recognition were assessed via WebNeuro® and global cognition via Montreal Cognitive Assessment). Depression symptoms were assessed via Beck Depression Inventory-II. There was a main effect of time for emotional recognition (p = 0.048), but there were no other changes in cognition or depression symptoms. Regardless of intervention or Val66Met polymorphism, high cadence cycling does not alter cognition or depression symptoms after three sessions in one week.

Sign in / Sign up

Export Citation Format

Share Document