A Comparison Between Self-Reported and Investigator-Measured Cardiovascular Risk-Related Biometric Numbers

2021 ◽  
pp. 019394592110135
Author(s):  
Sohye Lee ◽  
Catherine Pantik ◽  
Sree Duggirala ◽  
Ruth Lindquist
Keyword(s):  
Cardiovascular Risk ◽  
Fasting Blood Glucose ◽  
Health Assessment ◽  
Density Lipoprotein ◽  
Educational Interventions ◽  
Personal Knowledge ◽  
Future Research ◽  
Cardiovascular Risks ◽  
Convenience Sample ◽  
Glucose Levels

The purpose of this study was to examine individuals’ knowledge of cardiovascular risk-related biometric numbers and to compare self-reported and investigator-measured numbers in a convenience sample of adults in the Midwest region. Sociodemographic data and personal knowledge of cardiovascular risk-related biometric numbers were assessed using self-reported questionnaires. Investigators conducted health assessments to obtain biometric numbers. Among the 224 participants, participants’ reported knowledge about their cardiovascular risk-related biometric numbers was low, especially for high-density lipoprotein and fasting blood glucose levels. Participants’ knowledge was associated with education level and the recency of their last healthcare visit for health assessment. We found statistically significant mean differences between self-reported and investigator-measured blood pressure, and weight. This study found that there were discrepancies between self-reported and investigator-measured cardiovascular risk-related numbers. Future research is needed to develop educational interventions to improve personal knowledge of cardiovascular risks.

scholarly journals Distribution and Characteristics of Hypouricemia within the Japanese General Population: A Cross-Sectional Study

Medicina ◽  
2019 ◽  
Vol 55 (3) ◽  
pp. 61 ◽  
Author(s):  
Shin Kawasoe ◽  
Kazuki Ide ◽  
Tomoko Usui ◽  
Takuro Kubozono ◽  
Shiro Yoshifuku ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cardiovascular Risks ◽  
Cross Sectional ◽  
Glucose Levels ◽  
Body Mass Indexes ◽  
Estimated Glomerular Filtration Rates

Background and objectives: There is insufficient epidemiological knowledge of hypouricemia. In this study, we aimed to describe the distribution and characteristics of Japanese subjects with hypouricemia. Materials and Methods: Data from subjects who underwent routine health checkups from January 2001 to December 2015 were analyzed in this cross-sectional study. A total of 246,923 individuals, which included 111,117 men and 135,806 women, met the study criteria. The participants were divided into quartiles according to their serum uric acid (SUA) levels. We subdivided the subjects with hypouricemia, which was defined as SUA level ≤ 2.0 mg/dL, into two groups and compared their characteristics, including their cardiovascular risks. Results: The hypouricemia rates were 0.46% overall, 0.21% for the men and 0.66% for the women (P < 0.001). The number of the subjects with hypouricemia showed two distributions at SUA levels of 0.4–1.1 mg/dL (lower hypouricemia group), which included a peak at 0.7–0.8 mg/dL, and at SUA levels of 1.4–2.0 mg/dL (higher hypouricemia group). The men in the higher hypouricemia group had lower body mass indexes (BMI) and triglyceride (TG) levels and had higher fasting blood glucose levels than those in the lower hypouricemia group. The women in the higher hypouricemia group were younger; had lower BMI, total protein, TG, total cholesterol and low-density lipoprotein cholesterol levels; and had higher estimated glomerular filtration rates levels compared to those in the lower hypouricemia group. Conclusions: The characteristics of the individuals in the lower and higher hypouricemia groups differed significantly, indicating different pathophysiologies within each group.

scholarly journals ASSOCIATION BETWEEN BLOOD LIPID PROFILE AND BLOOD GLUCOSE LEVELS IN MEN WITH CORONARY HEART DISEASE, METABOLIC SYNDROME, AND TYPE 2 DIABETES MELLITUS

2013 ◽  
Vol 12 (5) ◽  
pp. 29-33
Author(s):  
S. A. Matveeva
Keyword(s):  
Blood Glucose ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
Lipoprotein Cholesterol ◽  
Blood Lipid Profile ◽  
Glucose Levels ◽  
Blood Glucose Levels

Aim.To study the associations between blood lipid profile and blood glucose levels in men with coronary heart disease (CHD), stable effort angina (SEA), metabolic syndrome (MS), and Type 2 diabetes mellitus (DM-2).Material and methods.The study included 82 men (mean age 50,5±0,9 years) with CHD, Functional Class I–III SEA, MS, and DM-2. The following lipid profile parameters were assessed: total cholesterol (TCH), triglycerides (TG), low-density lipoprotein cholesterol (LDL–CH), very low-density lipoprotein cholesterol (VLDL–CH), high-density lipoprotein cholesterol (HDL–CH), atherogenic index (AI), and triglyceride index (TGI), together with fasting blood glucose.Results.There were positive (direct) associations between higher levels (>90th percentile) of lipid profile parameters (TCH, TG, LDL–CH, VLDL– CH, HDL–CH, AI, TGI) and blood glucose, as well as between lower levels (≤10th percentile) of lipid profile parameters (TCH, TG, LDL–CH, VLDL– CH, AI, TGI) and blood glucose. At the same time, there were negative (inverse) associations between lower lipid levels (≤10th percentile of TCH, TG, LDL–CH, VLDL–CH, HDL–CH, AI, TGI) and higher glucose levels (>90th percentile), as well as between higher lipid levels (>90th percentile of TCH, TG, LDL–CH, VLDL–CH, HDL–CH, AI, TGI) and lower glucose levels (≤10th percentile).Conclusion.Dyslipidemia and hyperglycemia demonstrate synergetic proatherogenic effects in patients with CHD, SEA, MS, and DM-2, as suggested by significant heterogeneous (direct and inverse) associations between lipid profile parameters and fasting blood glucose. The results obtained provide an opportunity for the assessment of risk levels, prognosis, and need for pharmacological prevention and treatment in patients with combined cardiovascular pathology. 

scholarly journals Cardiovascular risk according to plasma apolipoprotein and lipid profiles in a Canadian First Nation

2010 ◽  
Vol 31 (1) ◽  
pp. 33-38 ◽  
Author(s):  
ND Riediger ◽  
SG Bruce ◽  
TK Young
Keyword(s):  
Cardiovascular Risk ◽  
First Nations ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Age Groups ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Apolipoprotein A1 ◽  
First Nation ◽  
Future Research

Introduction Despite high diabetes rates among Canadian First Nations people, little is known about their cardiovascular disease risk. Our aim was to describe the apolipoprotein profile with respect to cardiovascular risk in a Canadian First Nation community. Methods In 2003, a representative sample of adult members of a Manitoba First Nation (N = 483) participated in a screening study for diabetes and diabetes complications. We assessed their cardiovascular risk factors. Results Sixty percent of women were at increased cardiovascular risk because of low apolipoprotein A1 (apoA1) levels, compared with 35% of men. The proportion of women with low apoA1 levels decreased with age, but the proportion with low high-density lipoprotein levels remained stable across age groups. Both apoB and apoA1 were significantly associated with obesity when age, sex, diastolic blood pressure, homocysteine, diabetes, and insulin resistance were controlled for. Conclusion Apolipoprotein and lipid profiles in this First Nation population suggest high cardiovascular risk. Future research should characterize the lipoprotein particle size in this population.

Cardiovascular Risk in Patients With Fasting Blood Glucose Levels Within Normal Range

2010 ◽  
Vol 106 (11) ◽  
pp. 1602-1605 ◽  
Author(s):  
David Pereg ◽  
Avishay Elis ◽  
Yoram Neuman ◽  
Morris Mosseri ◽  
Michael Lishner ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Normal Range ◽  
Glucose Levels ◽  
Blood Glucose Levels

scholarly journals Increased Small Dense LDL and Decreased Paraoxonase Enzyme Activity Reveals Formation of an Atherogenic Risk in Streptozotocin-Induced Diabetic Guinea Pigs

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Mutay Aslan ◽  
Filiz Ozcan ◽  
Ertan Kucuksayan
Keyword(s):  
Guinea Pigs ◽  
Polyacrylamide Gel Electrophoresis ◽  
Fasting Blood Glucose ◽  
Cholesterol Acyltransferase ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Pon1 Activity ◽  
Small Dense Ldl ◽  
Glucose Levels ◽  
Significant Difference

This study aimed to investigate LDL subfraction distribution as well as serum cholesteryl ester transfer protein (CETP), lecithin-cholesterol acyltransferase (LCAT), and paraoxonase (PON1) activity in streptozotocin-induced diabetic guinea pigs.Materials/Methods. Guinea pigs were given a single intraperitoneal (ip) injection of streptozotocin (STZ) and animals having fasting blood glucose levels greater than 200 mg/dl, were considered diabetic. Protein levels of LCAT and CETP were determined via ELISA. Paraoxonase activity was measured kinetically by the formation of phenol while LDL subfraction analysis was done by disc polyacrylamide gel electrophoresis.Results. Plasma glucose and high-density lipoprotein (HDL) cholesterol were significantly increased while total cholesterol and LDL cholesterol were significantly decreased in diabetic guinea pigs compared to controls. LDL subfraction analysis revealed a significant decrease in nonatherogenic LDL-2 subfraction and a significant increase in atherogenic LDL-4 subfraction in diabetic guinea pigs compared to controls. Plasma CETP and PON1 levels were significantly decreased while LCAT showed no significant difference in diabetic guinea pigs compared to controls.Conclusion. Decreased non-atherogenic LDL-1, LDL-2 subfractions, increased small dense LDL-4 subfraction, and decreased PON1 activity, reveals formation of an atherogenic risk in diabetic guinea pigs. Decrease in CETP levels supports the observed increase in HDL cholesterol levels in diabetic guinea pigs.

scholarly journals Dyslipidemia and cardiovascular risk in Afro-descendants: a study of the Quilombola communities in Maranhão, Brazil

2015 ◽  
Vol 10 (36) ◽  
Author(s):  
Maria do Carmo Lacerda Barbosa ◽  
José Bonifácio Barbosa ◽  
Luis Felipe Alves Guerra ◽  
Mirza Ferreira Lima Barbosa ◽  
Felipe Lacerda Barbosa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Lipoprotein Cholesterol ◽  
Cardiovascular Risks ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Prevalence

Objective: to evaluate the prevalence of cardiovascular risk factors associated with dyslipidemia in Quilombola communities in Maranhão, Brazil. Methods: a cross-sectional study was performed from February 2010 to November 2011. A total of 202 individuals belonging to the Quilombola communities in Codó, Maranhão were assessed. Risk factors associated with dyslipidemia and metabolic syndrome (MS) were evaluated. Results: the results showed a high prevalence of dyslipidemia (72.28%) and hypertension (43.07%). Isolated hypertriglyceridemia (38.61%) with normal levels of high-density lipoprotein cholesterol and low-density lipoprotein cholesterol was present in most individuals. Furthermore, the prevalence of MS and the estimated cardiovascular risks were low in this population. Conclusion: dyslipidemia, at the expense of triglycerides, and hypertension was highly prevalent. However, the frequency of other risk factors for cardiovascular events was low. A low prevalence of MS and cardiovascular risk according to the Framingham score for cardiovascular diseases was also identified.

scholarly journals Glycaemic, Lipidaemic and Antioxidant Profiles of Alloxan-Induced Diabetic Wistar Rats Treated with Glibenclamide and Aqueous Extract of Gongronema latifolium (Benth)

2016 ◽  
Vol 8 (4) ◽  
pp. 408-413
Author(s):  
Patrick Emeka ABA
Keyword(s):  
Wistar Rats ◽  
Combined Therapy ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Study Groups ◽  
Oral Route ◽  
Diabetic Rats ◽  
Glucose Levels ◽  
Male Wistar Rats

The current study investigated the ameliorative effects of combined therapy of glibenclamide and G. latifolium (GL) on several biochemical parameters of alloxaized Wistar rats. Thirty adult male Wistar rats assigned into 5 groups of 6 rats each were used for the study. Groups 2-5 were intraperitoneally injected with 160 mg/kg of alloxan monohydrate and upon establishment of diabetes (Fasting Blood Glucose (FBG) ≥ 126 mg/dl) were treated with 10 ml/kg distilled water (DW), 2 mg/kg glibenclamide, 200 mg/kg GL and 2 mg/kg glibenclamide and 200 mg/kg GL respectively. Rats in group 1 were not made diabetic and served as normal control. All the treatments were realized through daily oral route using gastric tube, for 21 days. Results indicated that the treatment of diabetic rats with a combination of glibenclamide and GL significantly reduced the elevated glucose levels, cholesterol, triacylglycerol, low density lipoprotein and malondialdehyde levels, along with increases in the high density lipoprotein, glutathione values and catalase activities, when compared to diabetic untreated group. It was concluded that the combined therapy of glibenclamide and GL showed superior antihyperglycemic, hypolipidaemic and antioxidant effects compared to either of them used alone.

An evaluation of the CARES® Dementia Basics Program among caregivers

2016 ◽  
Vol 29 (1) ◽  
pp. 45-56 ◽  
Author(s):  
Michelle L. Pleasant ◽  
Victor Molinari ◽  
John V. Hobday ◽  
Sam Fazio ◽  
Nancy Cullen ◽  
...  
Keyword(s):  
Educational Interventions ◽  
Future Research ◽  
Correct Identification ◽  
Dementia Caregivers ◽  
Convenience Sample ◽  
Formal Caregivers ◽  
Care Partners ◽  
Post Test ◽  
Centered Care

ABSTRACTBackground:In 2014, the state of Oregon established Oregon Care Partners to provide high quality, free training to all dementia caregivers. This study evaluated participants’ changes in knowledge, sense of competency in dementia caregiving, and ability to identify person-centered caregiving techniques after completing CARES® Dementia Basics online program, one of the educational resources available through this initiative.Methods:A convenience sample of informal and formal caregivers (N = 51) provided data at three points in time; pre-test, post-test, and a follow-up test after an additional 30-day period to determine sustained changes in knowledge, sense of competency, and person-centered care.Results:From pre-test to post-test, modest improvements were detected in sense of competence in performing dementia care (ps < 0.01) and dementia-based knowledge, F(2, 150) = 7.71, p < 0.001, a multivariate effect size of w2 = 0.09. Even though improvements in sense of competency were not universal, three out of five individual items demonstrated positive growth from pre-test to post-test as well as four out of the five items from pre-test to follow-up test. Importantly, gains observed in dementia-based knowledge from pre-test to post-test were largely maintained at the 30-day follow-up. No significant changes were found in the correct identification of person-centered techniques after the training F(5, 150) = 1.63, p = 0.19.Conclusions:Future research should investigate how best to maintain educational interventions within the caregiving environment and to assess subsequent skill change.

Lipid profiles in users of combustible and electronic cigarettes

2021 ◽  
pp. 1358863X2110093
Author(s):  
Sana Majid ◽  
Rachel J Keith ◽  
Jessica L Fetterman ◽  
Robert M. Weisbrod ◽  
Jessica Nystoriak ◽  
...  
Keyword(s):  
Electronic Cigarettes ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Lipid Profiles ◽  
Electronic Cigarette ◽  
Cardiometabolic Health ◽  
Cigarette Use ◽  
Glucose Levels

Electronic cigarette use has especially risen among adolescents and young adults. The aim of this study was to investigate fasting blood glucose and lipid profiles in chronic combustible cigarette and electronic cigarette users. We evaluated participants aged 21 to 45 ( n = 525, mean age 31 ± 7 years, 45% women) without established cardiovascular disease or risk factors who were combustible cigarette users ( n = 290), electronic cigarette users ( n = 131; 65 sole users and 66 dual users), or never users ( n = 104). In the first wave of enrollment (2014–2017), electronic cigarette users reported their products as first, second and third generation devices (e-cig users) and were all largely current (i.e. dual) or former (sole) combustible cigarette users, whereas in the second wave of enrollment (2019–2020), electronic cigarette users all reported pod-based device use (pod users) and included more sole users who were never smokers. In multivariable-adjusted analyses comparing to never users, both sole e-cig users and combustible cigarette users had higher glucose and triglycerides and lower high-density lipoprotein (HDL) cholesterol levels. Dual e-cig users showed higher triglycerides and very-low-density lipoprotein cholesterol, and lower HDL cholesterol compared to never users. In contrast, pod users (both sole and dual) had lipid profiles and glucose levels similar to never users. Overall, users of early generation electronic cigarettes display adverse metabolic profiles. In contrast, pod-based electronic cigarette users have similar lipid profiles to never users. Future studies are needed to understand the cumulative effects of electronic cigarette use on cardiometabolic health.

scholarly journals Cardiovascular risk in primary care: comparison between Framingham Score and waist circumference

2021 ◽  
Vol 11 (4) ◽  
pp. 53-60
Author(s):  
Nina Vitória de Souza Silva Andrade ◽  
Isis Marinho de Noronha ◽  
Larisse Xavier Almeida ◽  
Fernanda Siqueira ◽  
Tatiana Onofre
Keyword(s):  
Primary Care ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Waist Circumference ◽  
Density Lipoprotein ◽  
Weighted Kappa ◽  
Cross Sectional Study ◽  
Risk Category ◽  
Cardiovascular Risks ◽  
Cross Sectional

Objectives: To estimate and compare the cardiovascular risk using the Framingham risk score (FRS) and waist circumference (WC) in primary care individuals and, secondarily, determine the main factors associated with these scores. Methods: Cross-sectional study involving individuals of both sexes attended in a primary health unit and aging between 30 and 74 years. The cardiovascular risks (FRS and WC) were stratified as low, intermediate, and high. The weighted Kappa coefficient was used to assess agreements between scores. Results: Fifty-five individuals (52.8 ± 9.4 years, 70.9% women) were evaluated. Using the FRS, 40.0% of the sample presented a low risk, 45.5% intermediate risk, and 14.5% high risk of cardiovascular disease. Conversely, when analyzed using the WC score, the highest frequency (71%) was observed in the high-risk category. Also, no agreement (K= 0.36; p= 0.55) was found between scores. FRS was associated with hypertension (p<0.01), diabetes (p=0.01), and stress in women (p=0.01), while the WC score was associated with hypertension (p=0.02), obesity (p<0.01), and high-density lipoprotein cholesterol HDL-c (p=0.03). Conclusions: Primary care individuals presented intermediate cardiovascular risk in the FRS and high risk in the WC, with no agreement between scores. Hypertension, diabetes, stress, obesity, and HDL-c represented the factors that were most associated with these scores.

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