Fetal Pathology in an Aborted Holstein Fetus Infected With Bovine Parainfluenza Virus-3 Genotype A

2018 ◽  
Vol 56 (2) ◽  
pp. 277-281 ◽  
Author(s):  
Melissa Macías-Rioseco ◽  
Santiago Mirazo ◽  
Francisco A. Uzal ◽  
Martín Fraga ◽  
Caroline Silveira ◽  
...  
Keyword(s):  
Small Intestine ◽  
Scientific Literature ◽  
Current Knowledge ◽  
Parainfluenza Virus ◽  
Respiratory Pathogen ◽  
Rt Pcr ◽  
Fetal Autopsy ◽  
Bovine Parainfluenza Virus ◽  
Fetal Pathology ◽  
Genotype A

Bovine parainfluenza virus-3 (BPIV-3) is a recognized respiratory pathogen of cattle, and it has also been identified in aborted fetuses. However, little is known of this agent as a reproductive pathogen and detailed descriptions of fetal pathology on natural cases are lacking in the scientific literature. This article describes and illustrates lesions in a fetus spontaneously aborted by a first-calving Holstein heifer, naturally infected with BPIV-3 genotype A, broadening the current knowledge on fetal pathology by this virus. Fetal autopsy revealed diffusely reddened, rubbery and unexpanded lungs. Histologically, there was necrotizing bronchiolitis/alveolitis with intraluminal fibrin exudate and syncytial cells in the bronchiolar/alveolar spaces, and non-suppurative peribronchiolitis and perivascular interstitial pneumonia. In the small intestine there was multifocal necrotizing cryptitis and occasional necrotic syncytial enterocytes. Intralesional and extralesional BPIV-3 antigen was detected by immunohistochemistry in the lung and small intestine, and BPIV-3a was identified in fetal tissues by RT-PCR and sequencing.

scholarly journals Isolation of a Divergent Strain of Bovine Parainfluenza Virus Type 3 (BPIV3) Infecting Cattle in China

Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 489 ◽  
Author(s):  
Élcio Leal ◽  
Cun Liu ◽  
Zhanzhong Zhao ◽  
Yong Deng ◽  
Fabiola Villanova ◽  
...  
Keyword(s):  
Virus Type ◽  
Immune Escape ◽  
Parainfluenza Virus ◽  
Chinese Isolate ◽  
Respiratory Pathogens ◽  
Adult Cattle ◽  
Mdbk Cells ◽  
Type 3 ◽  
Bovine Parainfluenza Virus ◽  
Genotype A

Bovine parainfluenza virus type 3 (BPIV3) is one of the most important known viral respiratory pathogens of both young and adult cattle. It is also named “heat stress in transport”, causing morbidity and mass death. New variants of BPIV3 have been detected or isolated in China since 2008. Here, we isolate one BPIV3 strain (named BPIV3 BJ) in Madin-Darby bovine kidney (MDBK) cells from nasal samples collected in China. Phylogenetic analysis showed that our isolate is related to BPIV3 of the genotype A. The comparison of BPIV3-BJ and the reference Chinese isolate NM09 showed that these strains are highly divergent. We found many differences in the amino acid composition in the nucleocapsid (NP) protein among these genotype A strains. Since the NP protein has been implicated in immunization studies, our BPIV3 isolate will be useful for the development of immune assays and vaccine studies. The diversity of BPIV3 lineages that we found in China indicated ongoing evolution for immune escape. Our study highlights the importance of genetic surveillance for determining the effect of BPIV3 variability on pathogen evolution and population-scale immunity.

scholarly journals Characterisation of the First Bovine Parainfluenza Virus 3 Isolate Detected in Cattle in Turkey

2019 ◽  
Vol 6 (2) ◽  
pp. 56 ◽  
Author(s):  
Harun Albayrak ◽  
Zafer Yazici ◽  
Emre Ozan ◽  
Cuneyt Tamer ◽  
Ahmed Abd El Wahed ◽  
...  
Keyword(s):  
Respiratory Diseases ◽  
Virus Isolation ◽  
Severe Pneumonia ◽  
Epidemiological Studies ◽  
Parainfluenza Virus ◽  
Kidney Cells ◽  
Rt Pcr ◽  
Cattle Farm ◽  
Bovine Respiratory Diseases ◽  
Bovine Parainfluenza Virus

A respiratory disease outbreak on a cattle farm in northern Turkey produced respiratory tract symptoms and severe pneumonia symptoms in 20 calves. Eight calves died, and a lung specimen from one carcass was analysed for bacteria and for viruses of the Bovine respiratory diseases complex. Bacteriological analysis was negative, but antigen detection ELISA and RT-PCR results indicated the presence of Bovine parainfluenza virus (BPIV). Virus isolation succeeded on Madin-Darby Bovine Kidney cells, and subsequent whole genome sequencing and phylogenetic analysis identified BPIV-3c. This is the first report of BPIV-3c isolation from cattle in Turkey, indicating the need for more virological and epidemiological studies.

scholarly journals Shedding course of bovine respiratory syncytial virus and bovine parainfluenza 3 virus in calves vaccinated intranasally

2013 ◽  
Vol 57 (4) ◽  
pp. 479-483 ◽  
Author(s):  
Wojciech Socha ◽  
Jerzy Rola ◽  
Dariusz Bednarek ◽  
Renata Urban-Chmiel ◽  
Jan F. Żmudziński
Keyword(s):  
Respiratory Syncytial Virus ◽  
Specific Antibody ◽  
Bovine Respiratory Syncytial Virus ◽  
Parainfluenza Virus ◽  
Rt Pcr ◽  
Nasal Swabs ◽  
Before And After ◽  
Antibody Titres ◽  
Syncytial Virus ◽  
Bovine Parainfluenza Virus

Abstract Shedding time of bovine respiratory syncytial virus (BRSV) and bovine parainfluenza virus 3 (BPIV3) in calves vaccinated intranasally with modified live Rispoval RS-PI3 vaccine was determined. Blood and nasal swabs were collected on selected days before and after vaccination. Antibodies against BRSV and BPIV3 were tested by Respiratory ELISA Pentakit and the viral RNA was detected by RT-PCR. Twenty eight days after administration of the vaccine, a marked increase of specific antibody titres to BRSV and BPIV3 was detected in vaccinated calves. All animals were RT-PCR positive both for BRSV and BPIV3. Both viruses were excreted with nasal discharges within 8 d after vaccination but the course of shedding in individual calves was variable.

scholarly journals RT-PCR for detection of bovine parainfluenza virus type 3 (bPIV-3)

2018 ◽  
Vol 36 (3) ◽  
pp. 215 ◽  
Author(s):  
Rodrigo de Almeida Vaucher ◽  
Amauri Braga Simonetti ◽  
Paulo Michel Roehe
Keyword(s):  
Virus Type ◽  
Parainfluenza Virus ◽  
Rt Pcr ◽  
Type 3 ◽  
Bovine Parainfluenza Virus

scholarly journals Identification and molecular characterisation of bovine parainfluenza virus-3 and bovine respiratory syncytial virus - first report from Turkey

2019 ◽  
Vol 63 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Mehmet Ozkan Timurkan ◽  
Hakan Aydin ◽  
Ahmet Sait
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Disease ◽  
Bovine Respiratory Disease ◽  
Bovine Respiratory Syncytial Virus ◽  
Parainfluenza Virus ◽  
Molecular Characterisation ◽  
Rt Pcr ◽  
First Report ◽  
Syncytial Virus ◽  
Bovine Parainfluenza Virus

AbstractIntroduction:Bovine parainfluenza virus-3 (BPIV3) and bovine respiratory syncytial virus (BRSV) are the cause of respiratory disease in cattle worldwide. With other pathogens, they cause bovine respiratory disease complex (BRDC) in ruminants. The aim of the study was the detection and molecular characterisation of BPIV3 and BRSV from nasal swabs and lung samples of cows in and around the Erzurum region of eastern Turkey.Material and Methods:In total, 155 samples were collected. Of animals used in the study 92 were males and 63 females. The age of the animals was between 9 months and 5 years, mean 1.4 years. Most males were in the fattening period and being raised in open sheds; females were in the lactating period and kept in free stall barns. All samples were tested for the presence of viral genes using RT-PCR. Gene-specific primers in a molecular method (RT-PCR) identified BRSV (fusion gene) and BPIV3 (matrix gene) strains at the genus level.Results:RNA from BRSV and BPIV3 was detected in two (1.29%) and three (1.93%) samples, respectively, one of each of which was sequenced and the sequences were aligned with reference virus strains. Phylogenetic analyses clustered the strains in genotype C/BPIV3 and subgroup III/BRSV.Conclusion:The results indicate that BRSV and BPIV3 contribute to bovine respiratory disease cases in Turkey. This is the first report on their detection and molecular characterisation in ruminants in Turkey.

Phylogenetic analysis of the bovine parainfluenza virus type 3 from cattle herds revealing the existence of a genotype A strain in China

Virus Genes ◽  
2012 ◽  
Vol 45 (3) ◽  
pp. 542-547 ◽  
Author(s):  
Yong-Jun Wen ◽  
Xin-Chuan Shi ◽  
Feng-Xue Wang ◽  
Wei Wang ◽  
Shu-Qin Zhang ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Virus Type ◽  
Parainfluenza Virus ◽  
Cattle Herds ◽  
Type 3 ◽  
Bovine Parainfluenza Virus ◽  
Genotype A

Workplace experience of parents coping with perinatal loss: A scoping review

Work ◽  
2021 ◽  
pp. 1-11
Author(s):  
Sophie Meunier ◽  
Francine de Montigny ◽  
Sabrina Zeghiche ◽  
Dominique Lalande ◽  
Chantal Verdon ◽  
...  
Keyword(s):  
Interpersonal Relationships ◽  
Scoping Review ◽  
Qualitative Methodology ◽  
Scientific Literature ◽  
Current Knowledge ◽  
Perinatal Loss ◽  
Quantitative Studies ◽  
Workplace Experience ◽  
Returning To Work ◽  
Perinatal Grief

BACKGROUND: Perinatal loss affects many parents in the workforce. Yet, current knowledge about their workplace experience while facing this difficult event is sparse. OBJECTIVES: The goal of this study was to review and synthesize the extent of scientific literature on the specific experiences of workers coping with perinatal loss and the resulting bereavement. METHODS: A scoping review was carried out using eight different databases. A total of 15 references, all using a qualitative methodology, were identified. Most of the references focused on the experience of mothers and on late perinatal loss (from the 20th week of pregnancy). RESULTS: All references highlighted the taboo and the non-recognition of perinatal grief and bereavement in both organizational practices and interpersonal relationships with colleagues and immediate supervisors. They also emphasized the difficulties associated with returning to work after the loss and the significant changes in the meaning attributed to work. CONCLUSIONS: While the studies included in this review clearly indicate that perinatal loss can affect working life, larger, quantitative studies are needed to quantify this phenomenon and its impact on employees and their organizations.

scholarly journals A Comprehensive Review of the Ethnotraditional Uses and Biological and Pharmacological Potential of the Genus Mimosa

2021 ◽  
Vol 22 (14) ◽  
pp. 7463
Author(s):  
Ismat Majeed ◽  
Komal Rizwan ◽  
Ambreen Ashar ◽  
Tahir Rasheed ◽  
Ryszard Amarowicz ◽  
...  
Keyword(s):  
Web Of Science ◽  
Scientific Literature ◽  
Therapeutic Potential ◽  
Current Knowledge ◽  
Folk Medicine ◽  
Nutritional Values ◽  
Biological Potential ◽  
The World ◽  
The Future ◽  
Pharmacological Potential

The Mimosa genus belongs to the Fabaceae family of legumes and consists of about 400 species distributed all over the world. The growth forms of plants belonging to the Mimosa genus range from herbs to trees. Several species of this genus play important roles in folk medicine. In this review, we aimed to present the current knowledge of the ethnogeographical distribution, ethnotraditional uses, nutritional values, pharmaceutical potential, and toxicity of the genus Mimosa to facilitate the exploitation of its therapeutic potential for the treatment of human ailments. The present paper consists of a systematic overview of the scientific literature relating to the genus Mimosa published between 1931 and 2020, which was achieved by consulting various databases (Science Direct, Francis and Taylor, Scopus, Google Scholar, PubMed, SciELO, Web of Science, SciFinder, Wiley, Springer, Google, The Plant Database). More than 160 research articles were included in this review regarding the Mimosa genus. Mimosa species are nutritionally very important and several species are used as feed for different varieties of chickens. Studies regarding their biological potential have shown that species of the Mimosa genus have promising pharmacological properties, including antimicrobial, antioxidant, anticancer, antidiabetic, wound-healing, hypolipidemic, anti-inflammatory, hepatoprotective, antinociceptive, antiepileptic, neuropharmacological, toxicological, antiallergic, antihyperurisemic, larvicidal, antiparasitic, molluscicidal, antimutagenic, genotoxic, teratogenic, antispasmolytic, antiviral, and antivenom activities. The findings regarding the genus Mimosa suggest that this genus could be the future of the medicinal industry for the treatment of various diseases, although in the future more research should be carried out to explore its ethnopharmacological, toxicological, and nutritional attributes.

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