scholarly journals E-diary use in clinical headache practice: A prospective observational study

Cephalalgia ◽  
2021 ◽  
pp. 033310242110103
Author(s):  
Daphne S van Casteren ◽  
Iris E Verhagen ◽  
Irene de Boer ◽  
Simone de Vries Lentsch ◽  
Rolf Fronczek ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Observational Study ◽  
Gold Standard ◽  
Prospective Observational Study ◽  
Medication Use ◽  
Acute Medication ◽  
Headache Clinic ◽  
Automated Algorithms ◽  
Migrainous Headache ◽  
Headache Patients

Aim To determine whether our E-diary can be used to diagnose migraine and provide more reliable migraine-related frequency numbers compared to patients’ self-reported estimates. Methods We introduced a self-developed E-diary including automated algorithms differentiating headache and migraine days, indicating whether a patient has migraine. Reliability of the E-diary diagnosis in combination with two previously validated E-questionnaires was compared to a physician’s diagnosis as gold standard in headache patients referred to the Leiden Headache Clinic (n = 596). In a subset of patients with migraine (n = 484), self-estimated migraine-related frequencies were compared to diary-based results. Results The first migraine screening approach including an E-headache questionnaire, and the E-diary revealed a sensitivity of 98% and specificity of 17%. In the second approach, an E-migraine questionnaire was added, resulting in a sensitivity of 79% and specificity of 69%. Mean self-estimated monthly migraine days, non-migrainous headache days and days with acute medication use were different from E-diary-based results (absolute mean difference ± standard deviation respectively 4.7 ± 5.0, 6.2 ± 6.6 and 4.3 ± 4.8). Conclusion The E-diary including algorithms differentiating headache and migraine days showed usefulness in diagnosing migraine. The use emphasised the need for E-diaries to obtain reliable information, as patients do not reliably recall numbers of migraine days and acute medication intake. Adding E-diaries will be helpful in future headache telemedicine.

Factors associated with frovatriptan response in patients with migraine: A prospective, observational study

Cephalalgia ◽  
2015 ◽  
Vol 36 (5) ◽  
pp. 493-498 ◽  
Author(s):  
Jong-Geun Seo ◽  
Sung-Pa Park
Keyword(s):  
Major Depressive Disorder ◽  
Risk Factor ◽  
Observational Study ◽  
Confidence Interval ◽  
Depressive Disorder ◽  
Odds Ratio ◽  
Prospective Observational Study ◽  
Major Depressive ◽  
Factors Associated ◽  
Headache Clinic

Background Almost one-third of patients with migraine do not adequately respond to triptans. We examined factors contributing to frovatriptan response in patients with migraine. Methods We enrolled new patients with migraine who consecutively visited our headache clinic. Eligible patients were instructed to take 2.5 mg of frovatriptan as soon as possible after migraine attack. The responsiveness was determined by whether headache was relieved or absent within 4 hours after the intake of frovatriptan. We assessed frovatriptan to be efficacious when headache responded to its administration in at least one of two successive migraine attacks and inefficacious when headache was not relieved in either attack. We included demographic, clinical and psychiatric variables in the analysis of factors associated with frovatriptan response. Results Of 128 eligible patients, 28 (21.9%) experienced frovatriptan inefficacy. In 24 patients with current major depressive disorder, 12 (50.0%) had frovatriptan inefficacy. Only current major depressive disorder was identified as a risk factor for inefficacy (odds ratio = 5.500, 95% confidence interval 2.103–14.382, p = 0.001). Conclusions Depression may be a risk factor of frovatriptan inefficacy in patients with migraine, even though half of patients with major depressive disorder respond to frovatriptan.

scholarly journals Comparison of blood loss in endoscopic powered adenoidectomy and conventional curettage

2019 ◽  
Vol 5 (3) ◽  
pp. 577
Author(s):  
Nithya Krishnakumar ◽  
N. K. Bashir ◽  
Girish Raj
Keyword(s):  
Radiofrequency Ablation ◽  
Standard Deviation ◽  
Blood Loss ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Conventional Technique ◽  
Nasal Endoscope ◽  
Medical College ◽  
Lower Blood ◽  
The Difference

<p class="abstract"><strong>Background:</strong> Adenoidectomy is one of the most common surgeries done in children. Over the years many techniques have evolved like powered adenoidectomy, radiofrequency ablation, electro cautery etc. Use of endoscopes has enabled surgeons to perform adenoidectomy under direct vision. The objectives of the study were to compare blood loss of conventional and endoscopic assisted powered adenoidectomy.</p><p class="abstract"><strong>Methods:</strong> In this a prospective observational study of 30 children attending ENT department in MES Medical College was done. In the conventional technique, adenoidectomy was done using St Claire Thomson adenoid curette. In powered adenoidectomy technique, micro debrider was used under guidance of 0<sup>0</sup> nasal endoscope (2.7 mm). Intra operatively blood loss during surgery were looked for and noted in both groups.  </p><p class="abstract"><strong>Results:</strong> In the study of 30 children divided in to 2 groups who are comparable statistically. Average blood loss in patients who underwent CA was 38.53 ml and in patients who underwent EAA was 28.27 ml, with standard deviation of 4.704 and 3.863 respectively. The difference in mean blood loss was 10.26 ml.</p><p class="abstract"><strong>Conclusions:</strong> Endoscopic assisted powered adenoidectomy has lower blood loss as compared to conventional adenoidectomy.</p>

scholarly journals Medication Use as a Contributor to Fluid Overload in the PICU: A Prospective Observational Study

2017 ◽  
Vol 07 (02) ◽  
pp. 069-074 ◽  
Author(s):  
Kelli Crowley ◽  
Carol Vetterly ◽  
Keito Hoshitsuki ◽  
Alaina Koval ◽  
Joseph Carcillo ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Fluid Intake ◽  
Fluid Overload ◽  
Medication Use ◽  
The Mean

AbstractIn this prospective observational study, we explored the association of daily fluid intake from medication use with fluid overload in 75 children beginning 24 hours after intubation. The mean percent daily fluid intake from medications was 29% in the overall cohort. Excess intake and inadequate output contributed significantly to fluid overload. In the 28 patients who became ≥10% fluid overloaded, the mean percent daily fluid intake from medications was 34%, but just 23% in the patients who did not. Awareness of volume contribution and maximized concentration of parenteral medications when able may lessen the burden of fluid overload.

scholarly journals Heart failure care and outcomes in a Tanzanian emergency department: A prospective observational study

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254609
Author(s):  
Sainikitha Prattipati ◽  
Francis M. Sakita ◽  
Godfrey L. Kweka ◽  
Tumsifu G. Tarimo ◽  
Timothy Peterson ◽  
...  
Keyword(s):  
Heart Failure ◽  
Emergency Department ◽  
Observational Study ◽  
Clinical Diagnosis ◽  
Prospective Observational Study ◽  
Medication Use ◽  
Sub Saharan Africa ◽  
Prior History ◽  
Heart Failure Patients ◽  
History Of

Background The burden of heart failure is growing in sub-Saharan Africa, but there is a dearth of data characterizing care and outcomes of heart failure patients in the region, particularly in emergency department settings. Methods In a prospective observational study, adult patients presenting with shortness of breath or chest pain to an emergency department in northern Tanzania were consecutively enrolled. Participants with a physician-documented clinical diagnosis of heart failure were included in the present analysis. Standardized questionnaires regarding medical history and medication use were administered at enrollment, and treatments given in the emergency department were recorded. Thirty days after enrollment, a follow-up questionnaire was administered to assess mortality and medication use. Multivariate logistic regression was performed to identify baseline predictors of thirty-day mortality. Results Of 1020 enrolled participants enrolled from August 2018 through October 2019, 267 patients (26.2%) were diagnosed with heart failure. Of these, 139 (52.1%) reported a prior history of heart failure, 168 (62.9%) had self-reported history of hypertension, and 186 (69.7%) had NYHA Class III or IV heart failure. At baseline, 40 (15.0%) reported taking a diuretic and 67 (25.1%) reported taking any antihypertensive. Thirty days following presentation, 63 (25.4%) participants diagnosed with heart failure had died. Of 185 surviving participants, 16 (8.6%) reported taking a diuretic, 24 (13.0%) reported taking an antihypertensive, and 26 (14.1%) were rehospitalized. Multivariate predictors of thirty-day mortality included self-reported hypertension (OR = 0.42, 95% CI: 0.21–0.86], p = 0.017) and symptomatic leg swelling at presentation (OR = 2.69, 95% CI: 1.35–5.56, p = 0.006). Conclusion In a northern Tanzanian emergency department, heart failure is a common clinical diagnosis, but uptake of evidence-based outpatient therapies is poor and thirty-day mortality is high. Interventions are needed to improve care and outcomes for heart failure patients in the emergency department setting.

A prospective, observational study of medication use among outpatients with common solid tumors.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 9055-9055
Author(s):  
M. Weiss ◽  
J. Manola ◽  
M. A. Thompson ◽  
M. L. Thomas ◽  
M. Fisch
Keyword(s):  
Observational Study ◽  
Solid Tumors ◽  
Prospective Observational Study ◽  
Medication Use

scholarly journals Is outpatient hysteroscopy the new gold standard? Results from an 11 year prospective observational study

2016 ◽  
Vol 57 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Tony Ma ◽  
Emma Readman ◽  
Lauren Hicks ◽  
Jenny Porter ◽  
Melissa Cameron ◽  
...  
Keyword(s):  
Observational Study ◽  
Gold Standard ◽  
Prospective Observational Study ◽  
Outpatient Hysteroscopy

scholarly journals Identifying Medication Errors in a Tertiary Care Teaching Hospital: A Prospective Observational Study

2019 ◽  
Vol 9 (6-s) ◽  
pp. 103-106
Author(s):  
Peddolla Sushma Reddy ◽  
Vidya Biju ◽  
Inuganti Bhavana
Keyword(s):  
Health Care ◽  
Observational Study ◽  
Medication Error ◽  
Medication Errors ◽  
Teaching Hospital ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Medication Use ◽  
Prescribing Errors ◽  
Tertiary Care Teaching Hospital

Background: Medication error is defined as any avertable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the health care professional, patient and consumer. Medication errors may occur at any stage of the medication use process including ordering, transcription, dispensing, administering and monitoring.  Objective: The objective of the study is to assess the medication errors in a tertiary care hospital and to categorize them based on their nature and type. Methodology: A prospective observational study was conducted over a period of 3 months in a tertiary care teaching hospital. This study was carried out among 240 inpatients, admitted in General Medicine department of the hospital, who were selected randomly. During the study, inpatients case records were reviewed, which includes patient’s case history, diagnosis, medication order sheets, progress chart, laboratory investigations. The data collected were analyzed for identifying medication errors such as prescribing errors and administration errors. Each reported medication error was assessed using the National Coordinating Council for Medication Error Reporting and Prevention (NCCMERP) proposed index for categorizing medication errors. Results: A total number of 240 inpatients were enrolled in the study, out of which 82 patients have developed medication errors. The overall percentage of observed medication error was 34.16%. In our study medication errors were found more in males (70.7%) than in the females (29.3%). Prescribing errors (62.19%) were the most frequently occurring type of error, which was followed by administration errors (37.8%). In our study, we found that medication errors were more with antibiotics (37) followed by NSAIDs (19). 96 prescriptions were found having drug interactions. Conclusion: This study concludes that the overall incidence of medication error was found to be 34.16%. Most of the medication errors are clinically significant and it can prevent by working together in a health care team.  

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