ARDS in Fulminant Ornithosis and Treatment with Extracorporeal Lung Assist

2000 ◽  
Vol 23 (6) ◽  
pp. 371-374 ◽  
Author(s):  
A. Wichert ◽  
P. Lukasewitz ◽  
M. Häuser ◽  
J. Bittersohl ◽  
H. Lennartz
Keyword(s):  
English Language ◽  
Distress Syndrome ◽  
Clinical Development ◽  
Severe Respiratory Failure ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
The Past ◽  
Extracorporeal Lung Assist ◽  
Infection Parameters ◽  
Language Literature

We report a 47-year-old male patient with fulminant ornithosis who developed severe respiratory failure leading to acute respiratory distress syndrome (ARDS) complicated by gastrointestinal, neurological and renal symptoms. ARDS was successfully treated by extracorporeal lung assist. As leukocytosis is typically absent in ornithosis, C-reactive protein, interleukin 6 and procalcitonin were used as infection parameters in order to monitor clinical development. The English-language literature on severe cases of ornithosis requiring respiratory support over the past 30 years is reviewed.

scholarly journals MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN: DIAGNOSTIC MARKERS AND FEATURES OF PHARMACOTHERAPY

2021 ◽  
Vol 17 (1) ◽  
pp. 24-28
Author(s):  
M.V. Кhaitovych ◽  
L.M. Voroniuk ◽  
G.Yu. Borisova ◽  
N.V. Diudenko ◽  
N.M. Miagka
Keyword(s):  
Distress Syndrome ◽  
The United States ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Markers Of Inflammation ◽  
Laboratory Markers ◽  
Mucous Membranes ◽  
Coronavirus Infection ◽  
Polymerase Chain ◽  
Inflammatory Syndrome

Relevance. In 2020, children were hospitalized with fever and multisystem inflammation throughout the world during the COVID-19 pandemic. In the United States, this condition is called MIS-C (Multisystem Inflammatory Syndrome in Children). This syndrome is thought to be similar to the severe course of COVID-19 in adults (cytokine storm). The objective of the work is to evaluate the features of the course and pharmacotherapy of multisystem inflammatory syndrome in children. Materials and methods. The study included 17 children (10 boys and 7 girls) aged 3-16 years (on average – 9.5±3.4 years). Diagnosis of coronavirus infection was performed by polymerase chain reaction with real-time detection, determined the level of immunoglobulins M and G before coronavirus infection. Results. The duration of fever in patients was 5-21 days (average 8.1±4.0 days), the duration of inpatient treatment – 7-35 days (average 15.7±7.0 days). Blood albumin levels were reduced in 53.8% of children; the level of fibrinogen was increased in 88.2% of children, the level of C-reactive protein, ferritin, and D-dimer – in all patients. 15 (88.2%) children had pathology of the digestive system, 13 (76.5%) – cardiovascular system (7 children were diagnosed with carditis, 2 – dilation of coronary arteries, 7 – cardiac arrhythmia). Acute respiratory distress -syndrome was found in a 13-year-old girl, shock - in an 11-year-old boy, 11 children (64.7%) were diagnosed with the pathology of the respiratory system (pleurisy, pneumonia), skin and mucous membranes, and 4 children (23.5%) there were manifestations of central nervous system disorders (meningism, decreased reflexes, ataxia), in 2 (11.8%) – renal failure. On average, each patient had lesions of 3.9 ±1.2 systems. Conclusions. MIS-C was manifested by prolonged fever, high levels of laboratory markers of inflammation, hypoalbuminemia, hypercoagulation, often – pathological manifestations of the cardiovascular, digestive, respiratory systems, skin, and mucous membranes. The treatment included intravenous immunoglobulin, steroids, anticoagulant, and antibacterial therapy and was effective.

Efficacy and Safety of Acupuncture with Western Medicine for Rheumatoid Arthritis: A Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Xinhui Huo ◽  
Lili Liang ◽  
Xia Ding ◽  
Angshaer Bihazi ◽  
Haiyan Xu
Keyword(s):  
Western Medicine ◽  
Analogue Scale ◽  
English Language ◽  
Meta Analysis ◽  
Chinese Language ◽  
Efficacy And Safety ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Randomized Controlled ◽  
Erythrocyte Sedimentation

Objectives: In the present study, we assessed the therapeutic qualities of the combination of acupuncture with Western medicine to determine further lines of clinical research. <br><br>Methods: We searched English-language databases and Chinese-language databases for randomized controlled trials (RCTs) published up to February 2020. Two reviewers performed a meta-analysis of the efficacy and toxicity of the use of acupuncture with Western medicine for RA measured by a visual analogue scale (VAS), rheumatoid factor (RF), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP). <br><br>Results: In total, 9 RCTs involving 698 patients were included for analysis. VAS, ESR, CRP, and RF were all shown to favor the combination of acupuncture with Western medicine compared to Western medicine alone. ST36 (Zusanli), EX-UE9 (Baxie), Ll11 (Quchi), GB34 (Yanglingquan), TE14 (Jianliao) and TE4(Yangchi) were frequently used in 9 clinical trials. <br><br>Conclusion: Treatment using acupuncture with Western medicine was associated with higher efficacy and lower risks than treatment with Western medicine alone. ST36 (Zusanli), EX-UE9 (Baxie), Ll11 (Quchi), GB34 (Yanglingquan), TE14 (Jianliao) and TE4 (Yangchi) were frequently used in treatment of RA and had been verified with effect in clinical practice

Pectoralis Major Rupture: Presentation of Two Cases and Review of 74 Cases

1997 ◽  
Vol 5 (2) ◽  
pp. 118-122
Author(s):  
Hubert YM Chao ◽  
Ralph T Manktelow
Keyword(s):  
Surgical Management ◽  
Conservative Management ◽  
English Language ◽  
Surgical Repair ◽  
Case Reports ◽  
Pectoralis Major ◽  
Review Of The Literature ◽  
The Past ◽  
Sporting Activities ◽  
Language Literature

Pectoralis major rupture is uncommon. Injury usually occurs from sporting activities. The incidence and management of pectoralis major rupture is not well known, despite 74 case reports in the English language literature over the past 34 years. Two cases of chronic pectoralis ruptures and their successful surgical management are described. A review of the literature shows that most injuries occur at the humeral insertion, and most are complete ruptures. Distinguishing between complete and partial ruptures is important. Complete ruptures are best treated surgically in the acute situation. When chronic complete ruptures present, surgical repair yields fair to good results. Acute partial ruptures can be effectively managed conservatively or with surgery. Chronic partial ruptures can be managed surgically with good results, following unsatisfactory conservative management in the acute situation.

scholarly journals Novel complication of an emerging disease: Invasive Klebsiella pneumoniae liver abscess syndrome as a cause of acute respiratory distress syndrome

2018 ◽  
Author(s):  
Anupam Gupta ◽  
Saad Bhatti ◽  
Anatoly Leytin ◽  
Oleg Epelbaum
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Klebsiella Pneumoniae ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Liver Abscess ◽  
English Language ◽  
Distress Syndrome ◽  
Pyogenic Liver Abscess ◽  
The Subject ◽  
Language Literature

Klebsiella pneumoniae is an increasingly recognized cause of a unique invasive syndrome manifesting as pyogenic liver abscess and hematogenous extrahepatic dissemination to a variety of sites, including the lung. Originally described only in Asia, this entity has now been reported across continents and ethnicities. Intrathoracic complications of invasive Klebsiella pneumoniae liver abscess syndrome (IKPLAS) have been characterized sporadically but have not been the subject of an all-encompassing investigation. Review of the English-language literature yields no reports of the acute respiratory distress syndrome as a consequence of IKPLAS. Herein we report what, to our knowledge, is the first such description.

scholarly journals Biomarkers: A Definite Plus in Pneumonia

2009 ◽  
Vol 2009 ◽  
pp. 1-9 ◽  
Author(s):  
Hanssa Summah ◽  
Jie-Ming Qu
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Proinflammatory Cytokines ◽  
Leukocyte Count ◽  
Diagnostic Biomarker ◽  
C Reactive Protein ◽  
Ongoing Research ◽  
Easy Task ◽  
Reactive Protein ◽  
The Past

During the past few years, biomarkers have emerged as an indispensible tool in the diagnosis of pneumonia. To find an ideal diagnostic biomarker for pneumonia is not an easy task. Not only should it allow an early diagnosis of the condition, but it should also allow differential diagnosis from other noninfectious conditions. Ongoing research is being done in this field so as to put an array of biomarkers at the disposal of doctors to improve the diagnosis of pneumonia when patients present to them with cough or nonspecific symptoms which could easily be misinterpreted as symptoms of other conditions. Procalcitonin and soluble triggering receptor expressed on myeloid cells-1 have emerged as reliable diagnostic markers in pneumonia, and are better when compared to other markers, namely, C-reactive protein, leukocyte count, and proinflammatory cytokines. Many other biomarkers are being studied for their probable use in diagnosing pneumonia but have yet to prove their benefit.

C-reactive protein and respiratory distress syndrome

1993 ◽  
Vol 122 (1) ◽  
pp. 164
Author(s):  
Dursun Ali Senses ◽  
Mete F. Toppare ◽  
I. Safa Kaya ◽  
Uur Dilmen ◽  
Füsun Kitapçi
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
C Reactive Protein ◽  
Reactive Protein

The Role of Suppressing Inflammation in the Treatment of Atherosclerotic Cardiovascular Disease

2020 ◽  
Vol 54 (10) ◽  
pp. 1021-1029
Author(s):  
Yuani M. Roman ◽  
Adrian V. Hernandez ◽  
C. Michael White
Keyword(s):  
Cardiovascular Disease ◽  
High Risk ◽  
English Language ◽  
Atherosclerotic Cardiovascular Disease ◽  
C Reactive Protein ◽  
High Risk Patients ◽  
Reactive Protein ◽  
Risk Patients ◽  
Hs Crp ◽  
The Impact

Objective: To review the 3 anti-inflammatory drugs, canakinumab, colchicine, and methotrexate, that have been investigated in major clinical trials for treating patients with atherosclerotic cardiovascular disease (ASCVD). Data Sources: An Ovid MEDLINE literature search (1946 to February 2, 2020) was performed using search strategy [( C-reactive protein OR ASCVD OR cardiac disease OR cardiovascular disease) AND (canakinumab OR methotrexate OR Colchicine)]. Additional references were identified from the citations. Study Selection and Data Extraction: English-language studies assessing the impact of these 3 drugs on inflammation as measured by high-sensitivity C-reactive protein (hs-CRP) or the association with reducing ASCVD events were included. Data Synthesis: Canakinumab and colchicine significantly reduced ASCVD events in high-risk patients with median baseline hs-CRP levels of ~4.0 mg/L. Methotrexate was ineffective at reducing ASCVD events in high-risk patients, but their baseline hs-CRP concentrations were a median of <2 mg/L. In subgroup analyses of the Canakinumab Antiinflammatory Thrombosis Outcome Study (CANTOS), patients whose baseline hs-CRP was 2 to 4 mg/L had benefits from canakinumab therapy similar to those with baseline levels exceeding 4. Relevance to Patient Care and Clinical Practice: Even with the best current drug therapies, patients with underlying inflammation can benefit from the addition of both colchicine and canakinumab to further lower CV events. Given its cost, colchicine is a more attractive option. Conclusions: Patients at high risk of recurrent cardiovascular disease events with an hs-CRP of 2 mg/L or greater can reduce the occurrence of ASCVD events with canakinumab or colchicine therapy. Colchicine is the preferable option, in particular for those with myocardial infarction, given its more reasonable cost.

Second Tumors after Radiosurgery: Tip of the Iceberg or a Bump in the Road?

Neurosurgery ◽  
2003 ◽  
Vol 52 (6) ◽  
pp. 1436-1442 ◽  
Author(s):  
Jay S. Loeffler ◽  
Andrzej Niemierko ◽  
Paul H. Chapman
Keyword(s):  
Glioblastoma Multiforme ◽  
English Language ◽  
Malignant Tumors ◽  
Benign Tumors ◽  
Pathological Findings ◽  
The Road ◽  
The Past ◽  
Second Tumors ◽  
Prescription Volume ◽  
Language Literature

Abstract OBJECTIVE Radiosurgery-associated second tumors have been reported in four isolated patients during the past 2 years. In our own experience, we are aware of two additional patients. The purpose of this report is to call attention to this potentially emerging problem. METHODS A review of the English-language literature concerning patients with radiosurgery-associated second tumors was performed. In addition, we report on two patients in our own practice who were treated in the past year. RESULTS Four patients were found in the literature, and two additional patients were seen by the authors. Malignant tumors occurred as early as 6 years after radiosurgery. The pathological findings in three of these four malignant tumors were glioblastoma multiforme. Benign tumors developed between 16 and 19 years later. Tumors developed both within the full-dose prescription volume and in the lower-dose periphery. Of interest, three of the six patients experienced complications of the radiosurgery treatment before developing second tumors. CONCLUSION Although patients will increasingly be reported with second tumors after radiosurgery in the future, the overall incidence seems quite low and should not alter current radiosurgical practice. However, continual surveillance of treated patients should be considered.

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