Liposuction and Serum Lipids

1997 ◽  
Vol 14 (3) ◽  
pp. 345-346 ◽  
Author(s):  
Bruce Hildreth
Keyword(s):  
Serum Lipids ◽  
Elevated Serum ◽  
Lipid Levels

The effect of liposuction on serum lipids is unknown. This study evaluated the reduction in lipid levels following suction-assisted lipectomy (SAL) in 23 patients with preoperative elevated serum lipids. Sixty-five percent (15 patients) had reduction in lipids following SAL. The mechanism of this change is unknown and further, better controlled, studies are necessary.

scholarly journals Frizzled-related proteins 4 (SFRP4) rs1802073G allele predicts the elevated serum lipid levels during acitretin treatment in psoriatic patients from Hunan, China

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4637 ◽  
Author(s):  
Xingchen Zhou ◽  
Wu Zhu ◽  
Minxue Shen ◽  
Yijing He ◽  
Cong Peng ◽  
...  
Keyword(s):  
Serum Level ◽  
Serum Lipid ◽  
Serum Lipids ◽  
Elevated Serum ◽  
Density Lipoprotein ◽  
Serum Triglyceride ◽  
Lipoprotein Cholesterol ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Related Proteins

Background Acitretin is a second-generation synthetic retinoid, and is widely used for treating the severe psoriasis vulgaris. However, it should be chosen with caution for its cardiovascular risk, and it is reported that acitretin may increase the serum lipids. The purpose of this study is to investigate the relationship between the Frizzled-related proteins 4 (SFRP4) rs1802073 polymorphism and the changes of serum lipids in Chinese psoriatic patients during the treatment with acitretin. Methods In our study, 100 psoriatic patients were recruited systematically treated with acitretin (30 mg/day) for at least eight weeks. Data of the patients’ demographic and clinical characteristics and the results of serum triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were collected pre- and post-treatment. Results A total of 84 psoriatic patients were enrolled and divided into three groups by SFRP4 rs1802073 genotypes. The patients who carried with TT genotype had maintained levels of TG and LDL-C after acitretin treatment, while patients with GG/GT genotypes had significantly elevated levels of serum TG and LDL-C compared to the TT genotype (ΔTG%: 27.53 ± 59.13 vs −1.47 ± 37.79, p = 0.026, ΔLDL-C%: 10.62 ± 26.57 vs −1.29 ± 17.07, p = 0.042). The association of rs1802073 with TG and LDL-C profiles remained significant after adjusting for age, gender, and body mass index. Although without significance, the pre-post change in serum level of TC across rs1802073 GG/GT genotypes demonstrated a trend similar to TG and LDL, and the serum level of HDL-C demonstrated a trend opposite to TG, TC and LDL. Conclusions Our results demonstrated that SFRP4 rs1802073 polymorphism was found to be associated with elevated serum lipid levels after acitretin treatment, and it may serve as a genetic marker of safe and precise treatment for individual psoriatic patients.

Comparative Studies of the Influence of Elevated Serum Lipid Levels on the Pharmacokinetics of Diazepam in rabbits and humans

1980 ◽  
Vol 14 (11) ◽  
pp. 765-768 ◽  
Author(s):  
Lesław M. Wichliński ◽  
Edmund Sieradzki
Keyword(s):  
Serum Concentration ◽  
Comparative Studies ◽  
Serum Lipid ◽  
Serum Lipids ◽  
Elevated Serum ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Elevated Lipid

The influence of elevated serum lipids on the pharmacokinetics of diazepam was investigated in rabbits. The results obtained were then compared with similar results of experiments carried out in humans. The changes in the pharmacokinetics of diazepam due to elevated lipid levels have similar characteristics in animals and humans. Elevated serum lipid levels cause a decrease in diazepam serum concentration.

scholarly journals Reference intervals for serum lipids and prevalence of dyslipidaemia in 6–12-year-old children: The Health Oriented Pedagogical Project (HOPP)

2018 ◽  
Vol 46 (21_suppl) ◽  
pp. 21-27 ◽  
Author(s):  
Martin Frank Strand ◽  
Per Morten Fredriksen ◽  
Ole Petter Hjelle ◽  
Morten Lindberg
Keyword(s):  
Total Cholesterol ◽  
Serum Lipids ◽  
Venous Blood ◽  
Elevated Serum ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Reference Intervals ◽  
Age And Gender ◽  
Norwegian Population ◽  
And Gender

Aims: Elevated serum lipid concentrations in childhood are thought to be risk factors for the development of cardiovascular disease later in life. The present study aims to provide age- and gender-related reference intervals for total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, and non-HDL cholesterol in healthy school children. We also investigated the prevalence of dyslipidaemia using the published criteria for these biomarkers. Methods: Venous blood and anthropometric data were collected from 1340 children in the HOPP study, aged between 6 and 12 years. Age- and gender-related reference intervals (2.5th and 97.5th percentiles) were established according to the IFCC recommendations, using the software RefVal 4.10. Results: Gender differences were observed for total cholesterol and non-HDL cholesterol, but not for HDL cholesterol. Age differences were observed for total cholesterol. The reference intervals were in the range of 3.1–5.9 mmol/L for total cholesterol, 1.0–2.4 mmol/L for HDL cholesterol and 1.4–4.2 mmol/L for non-HDL cholesterol. Dyslipidaemia prevalence was as follows: increased TC 9.6%, decreased HDL 1.6%, and increased non-HDL 5.6%. Conclusions: Age- and gender-related reference intervals in a Norwegian population are similar to those reported in other countries. The prevalence of dyslipidaemia among Norwegian children is significant, emphasising the importance of appropriate reference intervals in clinical practice.

The importance of thyroid microsomal antibodies in the development of elevated serum TSH in middle-aged women: associations with serum lipids

1993 ◽  
Vol 39 (3) ◽  
pp. 275-280 ◽  
Author(s):  
K. W. Geul ◽  
I. L. L. Sluisveld ◽  
D. E. Grobbee ◽  
R. Docter ◽  
A. M. Bruyn ◽  
...  
Keyword(s):  
Serum Lipids ◽  
Elevated Serum ◽  
Middle Aged ◽  
Thyroid Microsomal Antibodies ◽  
Serum Tsh

Histopathology and regression of retinal hard exudates in diabetic retinopathy after reduction of elevated serum lipid levels

Ophthalmology ◽  
2003 ◽  
Vol 110 (11) ◽  
pp. 2126-2133 ◽  
Author(s):  
Michael Cusick ◽  
Emily Y Chew ◽  
Chi-Chao Chan ◽  
Howard S Kruth ◽  
Robert P Murphy ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Serum Lipid ◽  
Elevated Serum ◽  
Lipid Levels ◽  
Hard Exudates ◽  
Serum Lipid Levels

scholarly journals Low cholesterol levels in children predict impulsivity in young adulthood

2019 ◽  
Vol 32 (4) ◽  
pp. 196-205
Author(s):  
Katrin Tomson-Johanson ◽  
Tanel Kaart ◽  
Raul-Allan Kiivet ◽  
Toomas Veidebaum ◽  
Jaanus Harro
Keyword(s):  
Young Adults ◽  
Birth Cohort ◽  
Young Adulthood ◽  
Serum Lipid ◽  
Serum Lipids ◽  
Ldl Cholesterol ◽  
Lipid Levels ◽  
Cholesterol Levels ◽  
Serum Lipid Levels ◽  
Low Levels

AbstractObjective:Severe behavioural issues such as impulsive action and suicide have since long been associated with low levels of cholesterol. While it is known that cholesterol plays a role in neural development and hence low levels of serum lipids could have long-term effects on behaviour, no longitudinal studies showed the association of serum lipids levels with impulsivity. We aimed to examine the prognostic properties of serum lipid levels during childhood and adolescence on measures of impulsivity during early adulthood in a representative birth cohort sample.Methods:We have investigated whether serum lipid levels measured at 9, 15, 18 and 25 years of age have an association with impulsivity in 25 years old young adults. This analysis was based on data of the birth cohort representative samples of the Estonian Children Personality Behaviour and Health Study (original n = 1238). Impulsivity was self-reported with the Adaptive and Maladaptive Impulsivity Scale.Results:Total and low-density lipoprotein (LDL) cholesterol measured in boys aged 9, 15 and 18 years predicted disinhibition and thoughtlessness in 25-year-old young adults. High scores of disinhibition were associated with low total and LDL cholesterol levels in males but, while less consistently, with high total and LDL cholesterol levels in females. Cross-sectional analysis did not result in systematic outcomes.Conclusions:Serum lipid levels could have an impact on the development of Maladaptive Impulsivity starting from an early age. This effect of cholesterol continues throughout adolescence into young adulthood.

scholarly journals The relationship between measures of obesity and atherogenic lipids among Nigerians with hypertension

2019 ◽  
Vol 31 (3) ◽  
pp. 193-197
Author(s):  
Olamoyegun A Michael
Keyword(s):  
Serum Lipid ◽  
Serum Lipids ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Advanced Age ◽  
Newly Diagnosed ◽  
Lipid Levels ◽  
Anthropometric Indices ◽  
Study Population ◽  
The Relationship

AimThis study aimed to determine the relationship between measures of obesity and serum lipid levels among hypertensive patients.MethodsThis was a cross-sectional study in which participants newly diagnosed with hypertension formed the study population. A range of demographic and anthropometric data was obtained, including weight, height, and waist and hip circumference. Fasting serum lipids were also measured, including total cholesterol, high density lipoprotein cholesterol (HDL-C) and triglycerides (TG). Low density lipoprotein cholesterol (LDL-C) was calculated using Friedewald formula. Statistical analysis was then carried out to determine the relationship between anthropometric indices and lipid profile levels. ResultsThe study population consisted of 124 male and 290 female subjects with a mean age of 66±16.95 years (range, 30–100 years).The female subjects were older than the male subjects (p=0.020). Our analysis showed that 85%, 58.5% and 30.7% of the study population had abnormal waist circumference (WC), abnormal waist-hip ratio (WHR) and a body mass index (BMI) >25 kg/m2, respectively. Decreased HDL-C (70.1%) was the commonest lipid abnormality detected, followed by elevated LDL (6.0%). None of the anthropometric indices were independent predictors of abnormal lipid levels. However, advanced age and female sex were independent predictors for at least one serum lipid abnormality.ConclusionNone of the measures of obesity could independently predict abnormal lipid levels in individuals newly diagnosed with hypertension. However, female sex, advanced age and systolic blood pressure were independently associated with abnormal serum lipids. Encouraging regular exercise, and the possible addition of statins, may be beneficial in addressing both obesity and dyslipidaemia.

scholarly journals Factors Related to Serum Lipids Using Multilevel Quantile Mixed Model:  Analysis of Nationwide STEPs Survey 2016

2021 ◽  
Author(s):  
Parisa Mohseni ◽  
Davood Khalili ◽  
Shirin Djalalinia ◽  
Farshad Farzadfar ◽  
Yadollah Mehrabi
Keyword(s):  
Serum Lipids ◽  
Mixed Model ◽  
Communicable Disease ◽  
Random Effect ◽  
Vascular Diseases ◽  
Model Parameters ◽  
Lipid Levels ◽  
Related Factors ◽  
Cross Sectional ◽  
Mixed Model Analysis

Abstract Backgroundlipid disorder is a modifiable risk factor for diseases related to plaque formation in arteries such as heart attack, stroke and peripheral vascular diseases. Identifying related factors and diagnosis and treatment in time reduces the incidence of non - communicable diseases. The aim of this study was to determine factors associated with lipids based on a national survey data.MethodsData of 16757 individuals aged 25–64 years obtained from the Iranian national cross-sectional study of the risk factors of non-Communicable disease (STEPs) performed in 2016, through multi-stage random sampling, were analyzed. Because of clustered, hierarchical and skewed form of the data, factors related to total Cholesterol (TC), Triglycerides (TG), LDL-C, HDL-C, TG/HDL-C, TC/HDL-C, LDL-C/HDL-C were determined applying multilevel quantile mixed model. Parameters of the model were estimated on the basis of random effect of the province as well as urban or rural area for 10th, 25th, 50th, 75th and 90th quantiles. Statistical analyses were performed by R software version 4.0.2.ResultsSignificant relationship was found between age, BMI, waist circumference, diabetes, hypertension, smoking, physical activity, education level, and marital status with TC, LDL-C, HDL-C, LDL-C and LDL-C/HDL-C. With increasing BMI and WC, subjects had higher levels of serum lipids, especially in higher quantiles of lipid levels. Lipid levels were significantly increased among smokers and those with diabetes or hypertension. The random effects were also significant showing that there is a correlation between the level of lipids in provincial habitants as well as urban and rural areas.ConclusionThis study showed that the effect of each factor varies depending on the centiles of the lipids. Significant relationship was found between sociodemographic, Behaviors and anthropometric indices with lipid parameters.

scholarly journals A study of variation in serum lipid levels in patients with Plasmodium vivax malaria

2020 ◽  
Vol 7 (7) ◽  
pp. 1073
Author(s):  
Prashanth Kumar P. ◽  
Rashmi Amans Flora Nazareth
Keyword(s):  
Plasmodium Vivax ◽  
Vivax Malaria ◽  
Serum Lipid ◽  
Elevated Serum ◽  
Serum Triglyceride ◽  
Lipid Levels ◽  
College Hospital ◽  
Serum Triglycerides ◽  
Serum Lipid Levels ◽  
Plasmodium Vivax Malaria

Background: Malaria is a common protozoal infection. Plasmodium vivax malaria is the most common species distributed worldwide and in India. The vivax malarial infection is associated with various haematological and biochemical abnormalities, anaemia and thrombocytopenia among the frequently identified abnormal parameters. However vivax malaria is also associated with abnormal lipid levels including low cholesterol levels and normal to high serum triglyceride levels.Methods: This study is a cross-sectional observational study including 100 inpatients admitted to Medical College Hospital over a period of 18 months diagnosed with Plasmodium vivax malaria. The patients were selected based on inclusion and exclusion criteria. The relevant data was collected and analysed.Results: Vivax malaria infection was found to be more common among males (80%) and during third decade of life (51%). HDL Cholesterol was decreased in all cases, LDL Cholesterol and Total Cholesterol was also decreased in nearly all patients with only 1% cases having values above normal range. Serum Triglycerides was elevated more than 150 mg/dl in 69% cases with 25% cases having values above 200mg/dl. The hypocholestrolemia and hypertriglyceridemia were directly proportional to the thrombocytopenia, hyperbilirubinemia, elevated serum creatinine levels and parasite load.Conclusions: This study demonstrates the presence of altered serum lipid levels in the form of hypocholesterolemia and hypertriglyceridemia in cases of Plasmodium vivax malaria mono infection. This study also shows that the above lipid alterations were found to be deranged to greater extent in clinically, haematologically and biochemically severe form of infections.

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