The Correlation Between Arterial Lactate and Venous Lactate in Patients With Sepsis and Septic Shock

2016 ◽  
Vol 33 (2) ◽  
pp. 116-120 ◽  
Author(s):  
Pongdhep Theerawit ◽  
Chalermpon Na Petvicharn ◽  
Viratch Tangsujaritvijit ◽  
Yuda Sutherasan
Keyword(s):  
Characteristic Curve ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Strongly Correlated ◽  
Cross Sectional ◽  
Arterial Lactate ◽  
Paired Samples ◽  
The Mean ◽  
Sepsis And Septic Shock ◽  
The Relationship

Background: Applying peripheral venous lactate instead of arterial lactate in clinical practice is questionable because of deviation between both values. We aimed to find the relationship between the arterial lactate and the peripheral venous lactate before reasoned that the venous lactate could be used in substitution to the arterial lactate in sepsis. Methods: We conducted a prospective, cross-sectional study at a university hospital. The patients with sepsis in ICU who required lactate level monitoring were enrolled in this research. The correlation and agreement between arterial lactate (A-LACT) and peripheral venous lactate (V-LACT) were the primary outcomes. Results: A total of 63 paired samples were collected. The A-LACT and V-LACT were strongly correlated ( r = .934, P < .0001, r2 = .873). The regression equation was A-LACT = (0.934 × V-LACT) − 0.236. The mean difference between V-LACT and A-LACT was 0.66 ± 1.53 mmol/L. The 95% limits of agreement were between −3.66 and 2.33 mmol/L. The V-LACT ≥ 4 mmol/L can predict A-LACT level ≥ 4 mmol/L with 87.5% sensitivity and 91.5% specificity, and the area under receiver operating characteristic curve was 0.948. Conclusion: The present study demonstrated a strong correlation between A-LACT and V-LACT, but an agreement between both parameters was poor. We suggest not to use the V-LACT in substitution to the A-LACT in sepsis regarding the absolute value and clearance rate, but the V-LACT ≥ 4.5 mmol/L may be used for predicting the A-LACT ≥ 4 mmol/L.

Psychopathological Factors Associated With Burnout in Intensive Care Nurses: A Cross-Sectional Study

2021 ◽  
pp. 107839032199972
Author(s):  
Erman Yıldız
Keyword(s):  
Intensive Care ◽  
Emotional Exhaustion ◽  
Cross Sectional Study ◽  
Personal Accomplishment ◽  
University Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Anxiety Depression ◽  
The Relationship

BACKGROUND: Although previous studies have separately revealed that parameters such as anxiety, depression, and secondary traumatic stress (STS) are associated with burnout, there is still a limited understanding of the relationship between anxiety, depression, and STS and burnout in intensive care unit (ICU) nurses. AIMS: To investigate the relationship between levels of burnout, anxiety, depression, and STS in ICU nurses. METHOD: A cross-sectional study was conducted with ICU nurses ( N = 164) from a university hospital in eastern Turkey. The participants completed the anxiety, depression, STS, and burnout scales along with the descriptive characteristics form. The data were analyzed using descriptive statistics, correlation, and logistic regression analysis. RESULTS: The mean scores for STS, anxiety, depression, and burnout were 40.60 ± 13.77, 17.14 ± 12.90, 13.28 ± 9.75 and 41.39 ± 14.87, respectively. The results showed that, in the ICU nurses, anxiety, depression, and STS components explained 61% of emotional exhaustion, 38% of depersonalization, and 13% of personal accomplishment. CONCLUSIONS: While the present findings supported the paradigm that burnout in ICU nurses is associated with STS, anxiety, and depression, they also revealed some details about the psychopathological factors associated with burnout. These details were as follows: (1) individuals who resorted to avoidance as a component of STS on a high level were more likely to experience emotional exhaustion and depersonalization, (2) individuals with severe depressive symptoms were more likely to experience a decrease in their personal accomplishment, and (3) individuals with anxiety symptoms were more likely to experience both emotional exhaustion and personal accomplishment.

scholarly journals Patients with pheochromocytoma exhibit low aldosterone renin ratio

2020 ◽  
Author(s):  
Tomoko Yamada ◽  
Hidenori Fukuoka ◽  
Yusei Hosokawa ◽  
Yukiko Odake ◽  
Kenichi Yoshida ◽  
...  
Keyword(s):  
Operating Characteristic ◽  
Adrenal Adenoma ◽  
Characteristic Curve ◽  
Plasma Renin ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Adrenal Tumors ◽  
Cross Sectional ◽  
Plasma Aldosterone Concentration ◽  
Sensitive Marker

Abstract Background Plasma renin activity (PRA) is generally increased in patients with pheochromocytoma (PCC) due to low circulating plasma volume and activation of β-1 adrenergic receptor signaling. However, there has been no study on the aldosterone renin ratio (ARR) in patients with PCC. To elucidate the issue, this study aimed to determine the PRA, plasma aldosterone concentration (PAC), and ARR in patients with PCC and compare them with those in patients with subclinical Cushing’s syndrome (SCS) and non-functioning adrenal adenoma (NFA). Methods In this retrospective single-center, cross-sectional study, 67 consecutive patients with adrenal tumors (PCC (n =18), SCS (n =18), and NFA (n =31)) diagnosed at Kobe University Hospital between 2008 and 2014 were enrolled. Results PRA was significantly higher in patients with PCC than in those with SCS and NFA (2.1 (1.3~2.8) vs. 0.7 (0.5~1.8) and 0.9 (0.6~1.4) ng/mL/h; p =0.018 and p =0.025). Although PACs were comparable among the three groups, ARR was significantly lower in patients with PCC than in those with SCS and NFA (70.5 (45.5~79.5) vs. 156.0 (92.9~194.5) and 114.9 (90.1~153.4); p =0.001 and p <0.001). Receiver operating characteristic curve analysis demonstrated that, in differentiating PCC from NFA, PRA >1.55 ng/mL/h showed a sensitivity of 70.0% and specificity of 80.6%. Interestingly, ARR <95.4 showed a sensitivity of 83.3% and specificity of 86.7%, which were higher than those in PRA. Conclusions ARR decreased in patients with PCC, which was a more sensitive marker than PRA. Further study is necessary to understand the usefulness of this convenient marker in the detection of PCC.

scholarly journals Obesity in Pregnant Adolescents: Clinical Correlates, Maternal and Fetal Outcomes

2020 ◽  
pp. 17-25
Author(s):  
Cecília Ogando Alfama ◽  
Amanda Vilaverde Perez ◽  
Mariana Sbaraini ◽  
Marianna Sperb ◽  
Rafaela da Silveira Corrêa ◽  
...  
Keyword(s):  
Gestational Hypertension ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Sectional Study ◽  
Pregnant Adolescents ◽  
Fetal Outcomes ◽  
Cross Sectional ◽  
The Relationship ◽  
Weight Excess ◽  
Lower Adherence

Objective: To evaluate the relationship between pregestational obesity and maternal and fetal outcomes in pregnant adolescents. Methods: Cross-sectional study conducted among puerperal teenagers of a university hospital in Southern Brazil. Structured questionnaires on sociodemographic and obstetric data were applied. Results: We evaluated 500 puerperal adolescents with a mean age of 17.77± 1.36. Of these, 31.2% (n=156) had pregestational weight excess. Pregestational weight excess was significantly associated with gestational hypertension (p=0.037) and diabetes (p=0.045), cesarean delivery (p=0.040),and lower adherence to prenatal care (24.7%, p=0.007).

scholarly journals Lactate dehydrogenase level as an early predictor of transient tachypnea of the newborn duration and complications

2020 ◽  
Author(s):  
Mada Osefori ◽  
Leen Jamel Doya ◽  
Bana Nezha ◽  
Adnan Dayoub
Keyword(s):  
Intensive Care ◽  
Lactate Dehydrogenase ◽  
Neonatal Intensive Care ◽  
Lactate Dehydrogenase Level ◽  
Cross Sectional Study ◽  
Postnatal Period ◽  
University Hospital ◽  
Cross Sectional ◽  
Duration Of Hospitalization ◽  
The Relationship

Abstract Background: Transient tachypnea of the newborn(TTNB) is a common cause of respiratory distress in the postnatal period. It is rarely associated with serious complications that need intensive care. Prediction of the complications during the first hours of hospitalization is very difficult, so the purpose of the current study is to investigate the relationship between lactate dehydrogenase (LDH) level in blood and the course of Transient tachypnea of the newborn (the duration of hospitalization, and the incidence of complications).Material and methods: In a cross-sectional study design included 120 neonates with Transient tachypnea of the newborn who had referred to the Neonatal Intensive Care Unit (NICU) at Tishreen University Hospital over 1 year period from January 2018 to January 2019. The neonates were classified according to Lactate dehydrogenase measurement as normal or high lactate dehydrogenase level in blood.Results: The results showed that there was a significant relationship between the level of lactate dehydrogenase and the duration of hospitalization, the incidence of complications, and the frequency of complications.Conclusions: lactate dehydrogenase might be useful for clinicians to predict the duration of hospitalization and the incidence of complications in neonates with TTNB.

scholarly journals Fibrinogen status in relapse and remission of childhood nephrotic syndrome

2016 ◽  
Vol 46 (4) ◽  
pp. 149
Author(s):  
Veronica Lily Limantara ◽  
Ida Bagus Mudita ◽  
I Ketut Suarta
Keyword(s):  
Nephrotic Syndrome ◽  
Serum Albumin ◽  
Cross Sectional Study ◽  
Fibrinogen Concentration ◽  
Strongly Correlated ◽  
Sectional Study ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Remission Status ◽  
The Mean

Objective To evaluate fibrinogen concentration of relapsing neph-rotic syndrome (NS) in children, and to investigate relationshipbetween fibrinogen with albumin and cholesterol.Methods A cross-sectional study among NS patients admitted topediatric outpatient clinic and pediatric ward at Sanglah Hospital,Denpasar, from November 1, 2003 to January 31, 2004. All pa-tients were evaluated for clinical and laboratory findings of relapseand remission, including edema, proteinuria, serum albumin, totalcholesterol, as well as total platelet count and fibrinogen concen-tration to evaluate coagulation parameters in nephrotic patients.Results There were 36 patients with the mean age of 7.4 (SD 2.3)years included in this study. Mean fibrinogen concentration in re-lapse state was 671.8 (SD 102.7) mg/dl, while in remission statewas 255.2 (SD 50.5 mg/dl); the mean difference was 416.6 mg/dl(95% CI 362.9;470.4; P<0.001). Fibrinogen was inversely andstrongly correlated with serum albumin concentrations (r=-0.91;P<0.001). Fibrinogen was positively and strongly correlated to to-tal cholesterol (r=0.80; P<0.001). Using multiple regression analy-sis, it was shown that only relapse/remission status was signifi-cantly associated with fibrinogen concentration (P<0.001).Conclusion Fibrinogen status is significantly correlated with re-lapse and remission status of NS in childhood patients.

scholarly journals Assessment of operative times of multiple surgical specialties in a public university hospital

2017 ◽  
Vol 15 (2) ◽  
pp. 200-205 ◽  
Author(s):  
Altair da Silva Costa Jr
Keyword(s):  
Operating Room ◽  
Operative Time ◽  
Cross Sectional Study ◽  
Public University ◽  
University Hospital ◽  
Cross Sectional ◽  
Mean Values ◽  
Operating Room Planning ◽  
Duration Of Surgery ◽  
The Mean

ABSTRACT Objective To evaluate the indicators duration of anesthesia, operative time and time patients stay in the operating rooms of different surgical specialties at a public university hospital. Methods It was done by a descriptive cross-sectional study based on the operating room database. The following stages were measured: duration of anesthesia, procedure time and patient length of stay in the room of the various specialties. We included surgeries carried out in sequence in the same room, between 7:00 a.m. and 5 p.m., either elective or emergency. We calculated the 80th percentile of the stages, where 80% of procedures were below this value. Results The study measured 8,337 operations of 12 surgical specialties performed within one year. The overall mean duration of anesthesia of all specialties was 178.12±110.46 minutes, and the 80th percentile was 252 minutes. The mean operative time was 130.45±97.23 minutes, and the 80th percentile was 195 minutes. The mean total time of the patient in the operating room was 197.30±113.71 minutes, and the 80th percentile was 285 minutes. Thus, the variation of the overall mean compared to the 80th percentile was 41% for anesthesia, 49% for surgeries and 44% for operating room time. In average, anesthesia took up 88% of the operating room period, and surgery, 61%. Conclusion This study identified patterns in the duration of surgery stages. The mean values of the specialties can assist with operating room planning and reduce delays.

scholarly journals The Relationship between Severity of Hearing Loss and Subjective Tinnitus Loudness among Patients Seen in a Specialist Tinnitus and Hyperacusis Therapy Clinic in UK

2019 ◽  
Vol 30 (08) ◽  
pp. 712-719 ◽  
Author(s):  
Hashir Aazh ◽  
Richard Salvi
Keyword(s):  
Hearing Loss ◽  
Regression Model ◽  
Pure Tone ◽  
Cross Sectional Study ◽  
Emotional Disturbances ◽  
Self Report ◽  
Strongly Correlated ◽  
Cross Sectional ◽  
The Impact ◽  
The Relationship

AbstractHearing loss is often associated with the phantom sound of tinnitus. However, the degree of the association between severity of hearing loss and tinnitus loudness taking into account the impact of other variables (e.g., emotional disturbances) is not fully understood. This is an important question for audiologists who are specialized in tinnitus rehabilitation as patients often ask whether the loudness of their tinnitus will increase if their hearing gets worse.To explore the relationship between tinnitus loudness and pure tone hearing thresholds.This was a retrospective cross-sectional study.445 consecutive patients who attended a Tinnitus and Hyperacusis Therapy Specialist Clinic in UK were included.The results of audiological tests and self-report questionnaires were gathered retrospectively from the records of the patients. Multiple-regression analysis was used to assess the relationship between tinnitus loudness, hearing loss and other variables.The regression model showed a significant relationship between the pure tone average (PTA) at the frequencies 0.25, 0.5, 1, 2, and 4 kHz of the better ear and the tinnitus loudness as measured via visual analogue scale (VAS), r (regression coefficient) = 0.022 (p < 0.001). Other variables significantly associated with tinnitus loudness were tinnitus annoyance (r = 0.49, p < 0.001) and the effect of tinnitus on life (r = 0.09, p = 0.006). The regression model explained 52% of the variance of tinnitus loudness.Although increased tinnitus loudness was associated with worse PTA, the relationship was very weak. Tinnitus annoyance and impact of tinnitus on life were more strongly correlated with tinnitus loudness than PTA.

Perfil de pacientes críticos com risco de olho seco: estudo transversal

2019 ◽  
Vol 17 (2) ◽  
Author(s):  
Jéssica Araújo Olímpio ◽  
Jéssica Naiara de Medeiros Araújo ◽  
Vanessa Pinheiro Barreto ◽  
Raianny Alves Costa Medeiros ◽  
Mércio Gabriel de Araújo ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Dry Eye ◽  
Invasive Mechanical Ventilation ◽  
Cross Sectional Study ◽  
Direct Care ◽  
University Hospital ◽  
Ocular Complications ◽  
Cross Sectional ◽  
The Mean

Aim: characterize the sociodemographic and clinical profile of patients with the diagnosis of dry eye risk nursing in intensive care unit. Methods: this is a cross-sectional study carried out at the intensive care unit of a university hospital located in the northeastern region of Brazil between January and July 2016. Results: it was observed that 51% of the patients were male, the mean age was 59.5 years, and 65.6% had a partner. Regarding the reasons for hospitalization, 53.1% were in the postoperative period and 46.9% were clinical patients; 49% were on invasive mechanical ventilation. Conclusion: to know the characteristics of patients with the diagnosis of dry-eye risk nursing in an intensive care unit becomes important in order to direct care for the prevention and early detection of the problem in order to reduce ocular complications

scholarly journals The relationship between body mass index before pregnancy and the amount of weight that should be gained during pregnancy: A cross-sectional study

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Resmiye Özdilek ◽  
Yılda Arzu Aba ◽  
Sena Dilek Aksoy ◽  
Bulat Aytek Şık ◽  
Yaşam Kemal Akpak
Keyword(s):  
Body Mass Index ◽  
Weight Gain ◽  
Pregnant Women ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean ◽  
The Relationship

Objective: To investigate the adaptation of pregnant women to the recommended weight gain range according to body mass index (BMI) and to determine the factors affecting them. Methods: This cross-sectional study was performed in a university hospital’s obstetrics and gynecology unit (tertiary center) in Turkey. This study was conducted between March 2018 and August 2018 (6 months) in pregnant women. Pregnant women with chronic disease and receiving treatment during antenatal follow-up, with twin pregnancy, with a fetus with a congenital abnormality, and nutritional disturbance were excluded from the study. Eight hundred twelve pregnant women with normal antenatal follow-up and who volunteered to participate were included in the study. Results: The mean age of the participants was 27.66±5.05 years. The mean weight and BMI before pregnancy were near standard in all participants. The group with the highest rate of recommended weight gain according to BMI before pregnancy was the group with low weight pregnant women. The ideal weight gain rate in all groups was 32%. Conclusions: The groups with overweight and obese pregnant women according to BMI before pregnancy had the highest rates of weight gain, above the recommended limits. BMI before pregnancy directly affects weight gain during pregnancy and the importance of pre-pregnancy counseling and weight loss is emphasized once again. doi: https://doi.org/10.12669/pjms.35.5.133 How to cite this:Ozdilek R, Aba YA, Aksoy SD, Sik BA, Akpak YK. The relationship between body mass index before pregnancy and the amount of weight that should be gained during pregnancy: A cross-sectional study. Pak J Med Sci. 2019;35(5):---------.  doi: https://doi.org/10.12669/pjms.35.5.133 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Parental Knowledge, Attitudes, and Behaviors Toward Their Epileptic Children at King Abdulaziz University Hospital: Cross-Sectional Study (Preprint)

2018 ◽  
Author(s):  
Abdulelah Kinkar ◽  
Dalya Alqarni ◽  
Abdulaziz Alghamdi ◽  
Sahal Wali ◽  
Nasser Alghamdi ◽  
...  
Keyword(s):  
Educational Level ◽  
Parental Knowledge ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Sectional Study ◽  
Significant Relation ◽  
Cross Sectional ◽  
Epileptic Children ◽  
King Abdulaziz University ◽  
The Mean

BACKGROUND Epilepsy is a chronic disease characterized by periodic seizures that result from abnormal integrated firing impulses in the brain. It is one of the most common neurological disorders. Over the past few years, there has been increasing awareness about the effect that having a child with epilepsy has on parents and the reciprocal impact of parental knowledge and attitudes regarding epilepsy on the affected child. OBJECTIVE This study aimed to assess parental knowledge, attitudes, and behavior toward their epileptic children. METHODS A cross-sectional study was conducted in 2018 by the Pediatric Neurology Department of King Abdulaziz University Hospital, Jeddah, the Kingdom of Saudi Arabia. A sample size of 115 of 332 parents who have a child diagnosed with epilepsy and aged 18 years or younger were recruited for this study. Statistical analysis was performed using SPSS version 21. Data analysis was performed using an independent <italic>t</italic> test, a chi-square test, one-way analysis of variance, and correlation analysis. RESULTS A total of 115 participants answered the questionnaire; of these, 65 (56.5%) were men, with an average age of 40.3 years, and the mean age of the children was 9.0 years. Overall, 85 (85/115, 73.9%) children were taken care of by both of their parents. The mean parental knowledge score was 7.49 (SD 2.08) out of 12, and it was significantly related to the educational level of the parent (<italic>P</italic>=.004). The knowledge question that was most frequently answered incorrectly was “Diagnosis of epilepsy is usually made based on at least two unprovoked seizures.” As only 28.7% (33/115) of participants chose the correct answer, mean parental attitude score was 26.51 (SD 4.284) out of 35, and there was no significant relation with the educational level of parents (<italic>P</italic>=.13); however, it was negatively correlated with the child’s age (<italic>P</italic>=.045). Mean parental behavioral score was 23.35 (SD 4.121) out of 35, and there was no significant relation with the educational level of the parents (<italic>P</italic>=.24). The most negatively answered question for the behavior section was “I can leave my child without supervision,” with a mean score of 2.25 (SD 1.09) out of 5. Gender did not play a significant role in parental knowledge, attitudes, or behavior (<italic>P</italic>=.44, <italic>P</italic>=.77, and <italic>P</italic>=.99, respectively). CONCLUSIONS Parental knowledge in our sample still needs improvement. Therefore, more awareness campaigns should be made for the community and for the parents of affected children to create a supportive environment for the children and help them thrive and develop.

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