scholarly journals Low Levels of Physical Activity During Critical Illness and Weaning: The Evidence–Reality Gap

2017 ◽  
Vol 34 (10) ◽  
pp. 818-827 ◽  
Author(s):  
Bronwen A. Connolly ◽  
Jessica L. Mortimore ◽  
Abdel Douiri ◽  
Joleen W. Rose ◽  
Nicholas Hart ◽  
...  
Keyword(s):  
Physical Activity ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Prolonged Mechanical Ventilation ◽  
Physical Activity Behavior ◽  
Ventilator Weaning ◽  
Physical Rehabilitation ◽  
Activity Level ◽  
University Teaching ◽  
Activity Levels

Background: Physical rehabilitation can benefit critically ill patients during intensive care unit (ICU) admission, but routine clinical practice remains inconsistent nor examined in prolonged mechanical ventilation patients transferred to a specialist ventilator weaning unit (VWU). Behavioral mapping is a sampling approach that allows detailed reporting of physical activity profiles. The objective of this study was to characterize the physical activity profile of critically ill patients in a UK ICU and VWU. Methods: Single-center, prospective observational study in a university teaching hospital. Patient observations, conducted Monday through Sunday from 08:30 am to 08:00 pm and for 1 minute every 10 minutes, included data points of patient location, people in attendance, and highest level of activity. Descriptive statistics were utilized to analyze and report data. Results: Forty-two ICU and 11 VWU patients were recruited, with 2646 and 693 observations, respectively, recorded. In the ICU, patients spent a median (interquartile range) of 100% (96%-100%) of the day (10.5 [10.0-10.5] hours) located in bed, with minimal/no activity for 99% (96%-100%) of the day (10.4 [9.7-10.5] hours). Nursing staff were most frequently observed in attendance with patients irrespective of ventilation or sedation status, although patients still spent approximately two-thirds of the day alone. Bed-to-chair transfer was the highest activity level observed. In the VWU, patients spent 94% (73%-100%) of the day (9.9 [7.7-10.5] hours) in bed and 56% (43%-60%) of time alone. Physical activity levels were higher and included ambulation. All physical activities occurred during physical rehabilitation sessions. Conclusions: These profiles of low physical activity behavior across both patients in the ICU and VWU highlight the need for targeted strategies to improve levels beyond therapeutic rehabilitation and support for a culture shift toward providing patients with, and engaging them in, a multidisciplinary, multiprofessional environment that optimizes overall physical activity.

Cytokines in Chronically Critically Ill Patients After Activity and Rest

2007 ◽  
Vol 8 (4) ◽  
pp. 261-271 ◽  
Author(s):  
Chris Winkelman ◽  
Patricia A. Higgins ◽  
Yea Jyh Kathy Chen ◽  
Alan D. Levine
Keyword(s):  
Physical Activity ◽  
Mechanical Ventilation ◽  
Critical Illness ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Prolonged Mechanical Ventilation ◽  
Serum Levels ◽  
Inflammatory Factors ◽  
Chronically Critically Ill ◽  
Critically Ill Adults

Inflammation, a common problem for patients in the intensive care unit (ICU), frequently is associated with serious and prolonged critical illnesses. To date, no study has examined whether physical activity influences inflammatory factors in critically ill adults. The objectives of this study were to (a) examine the relationships between type and duration of physical activity and serum levels of interleukin 6 (IL-6), a proinflammatory cytokine; IL-10, an anti-inflammatory cytokine; and their ratio and (b) determine if there are associations between cytokines or their ratio and activity or outcomes. This descriptive feasibility study investigated the approaches to measuring levels of physical activity and its relationship to serum levels of IL-6 and IL-10 and the ratio between them in patients with prolonged mechanical ventilation during periods of activity and rest. Measurements included serum IL-6 and IL-10 levels, direct observation and actigraphy, and prospective chart review. Ten critically ill patients who were mechanically ventilated for an average of 10 days in a large, urban, teaching hospital were enrolled. The average ratio of IL-6 to IL-10 improved after an average of 14.7 min of passive physical activity, typically multiple in-bed turns associated with hygiene. IL-6, IL-10, and their ratio were not associated with patient outcomes of weaning success or length of stay. High levels of IL-6 were associated with mortality. Cytokine balance may be improved by low levels of activity among patients with prolonged critical illness. The pattern of cytokines produced after activity may improve patients' recovery from prolonged critical illness and mechanical ventilation.

scholarly journals Arterial Carboxyhemoglobin Levels In COVID-19 Critically Ill Patients

2021 ◽  
Author(s):  
Paul Paccaud ◽  
Diego Castanares-Zapatero ◽  
Ludovic Gerard ◽  
Virginie Montiel ◽  
Xavier Wittebole ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Retrospective Cohort ◽  
Prolonged Mechanical Ventilation ◽  
Progressive Increase ◽  
University Teaching ◽  
Single Center ◽  
Parallel Increase ◽  
Over Time

Abstract Objective : Oxidative stress conditions may be responsible for an up-regulation of the expression of heme oxygenase (HO), the enzyme synthesizing carbon monoxide (CO) in cells. Elevated levels of arterial carboxyhemoglogin (aCOHb) have been found in critically ill patients, including those suffering from acute lung injury. We aimed to investigate the changes of aCOHb levels in COVID-19 critically ill patients.Design : Single center retrospective cohort study between March 1 and December 31, 2020.Setting: University teaching hospital with 900 beds including 48 ICU beds.Patients: Consecutive adults requiring ICU admission for severe COVID-19 infection.Measurements and main results : After exclusion of 23 patients who required extracorporeal membranous oxygenation (ECMO), a total of 135 patients was considered, from whom 76 required mechanical ventilation (MV) that was prolonged for more than 20 days in 28 patients. Demographics, laboratory values, treatment and outcomes were recorded. The evolution of aCOHb over time was investigated among survivors and non-survivors and among patients with or without MV. The admission and peak aCOHb values did not differ among survivors or non-survivors. In the patients with MV, there was a significant increase of aCOHb with time, with a biphasic evolution for the patients ventilated for more than 20 days: a parallel increase of aCOHb and PaCO2 followed by a trend to a plateau of aCOHb during PaCO2 recovery.Conclusions : Progressive increase in aCOHb from endogenous source is observed in COVID-19 patients requiring prolonged mechanical ventilation. Decrease of aCOHb appears slower than PaCO2 recovery.

scholarly journals Later sleep timing predicts accelerated summer weight gain among elementary school children: a prospective observational study

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Jennette P. Moreno ◽  
Javad Razjouyan ◽  
Houston Lester ◽  
Hafza Dadabhoy ◽  
Mona Amirmazaheri ◽  
...  
Keyword(s):  
Physical Activity ◽  
Observational Study ◽  
Sleep Duration ◽  
Obesity Prevention ◽  
Prospective Observational Study ◽  
Light Exposure ◽  
Activity Level ◽  
Activity Levels ◽  
School Year ◽  
Children’S Sleep

Abstract Objectives and background Social demands of the school-year and summer environment may affect children’s sleep patterns and circadian rhythms during these periods. The current study examined differences in children’s sleep and circadian-related behaviors during the school-year and summer and explored the association between sleep and circadian parameters and change in body mass index (BMI) during these time periods. Methods This was a prospective observational study with 119 children ages 5 to 8 years with three sequential BMI assessments: early school-year (fall), late school-year (spring), and beginning of the following school-year in Houston, Texas, USA. Sleep midpoint, sleep duration, variability of sleep midpoint, physical activity, and light exposure were estimated using wrist-worn accelerometry during the school-year (fall) and summer. To examine the effect of sleep parameters, physical activity level, and light exposure on change in BMI, growth curve modeling was conducted controlling for age, race, sex, and chronotype. Results Children’s sleep midpoint shifted later by an average of 1.5 h during summer compared to the school-year. After controlling for covariates, later sleep midpoints predicted larger increases in BMI during summer, (γ = .0004, p = .03), but not during the school-year. Sleep duration, sleep midpoint variability, physical activity levels, and sedentary behavior were not associated with change in BMI during the school-year or summer. Females tended to increase their BMI at a faster rate during summer compared to males, γ = .06, p = .049. Greater amounts of outdoor light exposure (γ = −.01, p = .02) predicted smaller increases in school-year BMI. Conclusions Obesity prevention interventions may need to target different behaviors depending on whether children are in or out of school. Promotion of outdoor time during the school-year and earlier sleep times during the summer may be effective obesity prevention strategies during these respective times.

scholarly journals Choroidal Thickness and Volume Modifications Induced by Aerobic Exercise in Healthy Young Adults

2020 ◽  
Author(s):  
Gema Insa-Sánchez ◽  
Lorena Fuentes-Broto ◽  
Alberto Cobos ◽  
Elvira Orduna Hospital ◽  
Francisco Segura ◽  
...  
Keyword(s):  
Physical Activity ◽  
Young Adults ◽  
Physical Exercise ◽  
Choroidal Thickness ◽  
Activity Level ◽  
Enhanced Depth Imaging ◽  
Activity Levels ◽  
Imaging Protocol ◽  
Post Exercise ◽  
Physical Activity Levels

<b><i>Introduction:</i></b> Our aim was to evaluate the changes in choroidal thickness (CT) and volume (CV) following aerobic physical exercise in healthy young adults. <b><i>Methods:</i></b> This study included 72 eyes from healthy volunteers between 22 and 37 years old. Using the International Physical Activity Questionnaire, total physical activity was computed. Measurements using an autorefractometer, ocular biometry, and spectral-domain optical coherence tomography using the Enhanced Depth Imaging protocol were taken. OCT was performed as a baseline measurement and after performing 10 min of dynamic physical exercise (3 and 10 min post-exercise). The choroidal layer was manually segmented, and the CT and CV in different areas from the Early Treatment Diabetic Retinopathy Study grid were obtained. <b><i>Results:</i></b> In healthy adults, at 3 min post-exercise, CT was higher in the subfoveal, the 3-mm nasal, and the 6-mm superior areas. Between 3 and 10 min post-exercise, the CT was reduced in all areas, and in some areas, the values were even smaller than the baseline measurements. The CV values showed changes after exercise similar to those of thickness. The total CV recovery after exercise was related to sex and physical activity level. <b><i>Conclusion:</i></b> Individuals with higher physical activity habits had greater CV at rest than those with lower physical activity levels. During exercise, healthy young people adjust CT and CV. At 3 min post-exercise, CT and CV increase. Women and individuals with greater physical activity levels reduce their total CV more than others during recovery.

scholarly journals Reduced level of physical activity during COVID-19 pandemic is associated with depression and anxiety levels: an internet-based survey

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Paulo José Puccinelli ◽  
Taline Santos da Costa ◽  
Aldo Seffrin ◽  
Claudio Andre Barbosa de Lira ◽  
Rodrigo Luiz Vancini ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mood Disorders ◽  
Physical Activity Level ◽  
Negative Impact ◽  
Mood State ◽  
Activity Level ◽  
Activity Levels ◽  
Depression And Anxiety ◽  
Social Distancing ◽  
Physical Activity Levels

Abstract Background The coronavirus disease 2019 (COVID-19) pandemic has resulted in a strong negative impact on economic and social life worldwide. It has also negatively influenced people’s general health and quality of life. The aim of the present study was to study the impact of social distancing on physical activity level, and the association between mood state (depression and anxiety level) or sex with actual physical activity levels, the change in physical activity caused by social distancing period, the adhesion level to social distancing, the adoption time of social distancing, family income and age. Methods A self-administered questionnaire with personal, quarantine, physical activity, and mood state disorders information’s was answered by 2140 Brazilians of both sex who were recruited through online advertising. Results The physical activity level adopted during the period of social distancing (3.5 ± 0.8) was lower than that the adopted prior to the pandemic period (2.9 ± 1.1, p < 0.001). Thirty percent of the participants presented symptoms of moderate/severe depression and 23.3% displayed moderate/severe anxiety symptoms. A greater presence of symptoms related to anxiety and depression were associated with low physical activity levels, low family monthly income, and younger age. A higher percentage of men who had no mood disorders was observed among those who were very active than among those less active. Conclusion The COVID-19 pandemic has a negative impact on physical activity. Those who reduced their level of physical activity had the highest levels of mood disorders. Therefore, physical activity programs should be encouraged, while respecting the necessary social distancing to prevent the spread of Severe Acute Respiratory Syndrome Coronavirus 2.

scholarly journals Physical activity level of adult cats with varied feeding frequency

2011 ◽  
Vol 106 (S1) ◽  
pp. S166-S169 ◽  
Author(s):  
Ping Deng ◽  
Ryan W. Grant ◽  
Kelly S. Swanson
Keyword(s):  
Physical Activity ◽  
Body Weight ◽  
Body Condition ◽  
Body Condition Score ◽  
Activity Level ◽  
Feeding Time ◽  
Activity Levels ◽  
Feeding Frequency ◽  
Condition Score ◽  
Adult Cats

The prevalence of feline obesity is influenced by numerous factors, including inactivity and overconsumption of food. The objective of the present study was to evaluate the effect of feeding frequency on physical activity in adult cats. A total of twelve healthy adult cats were used in a cross-over study consisting of 32 d. In each of the two periods, six cats were fed either two meals or four meals daily. Throughout the study, cats were fed the same diet at amounts to maintain body weight and body condition score. Cats were individually housed 4 h/d at each scheduled feeding time, while for the other 20 h, cats were group-housed to allow for voluntary physical activity in the room with a 16 h light–8 h dark cycle. Voluntary activity levels were evaluated using Actical activity collars for seven consecutive days in each period. Daily average activity level for two-meal-fed cats (20·04 (sem 2·19), activity counts/epoch (15 s)) was not different from four-meal-fed cats (20·14 (sem 2·15), activity counts/epoch (15 s); P>0·05). In conclusion, when group-housed cats are fed to maintain their body weight and body condition score, varied feeding frequency between twice and four times daily may not affect activity levels.

scholarly journals How Much Observation Is Enough? Refining the Administration of SOPARC

2011 ◽  
Vol 8 (8) ◽  
pp. 1117-1123 ◽  
Author(s):  
Deborah A. Cohen ◽  
Claude Setodji ◽  
Kelly R. Evenson ◽  
Phillip Ward ◽  
Sandra Lapham ◽  
...  
Keyword(s):  
Physical Activity ◽  
Los Angeles ◽  
Interobserver Reliability ◽  
Intraclass Correlation ◽  
Activity Level ◽  
Activity Levels ◽  
User Characteristics ◽  
Systematic Observation ◽  
Robust Estimate ◽  
Neighborhood Parks

Background:The Systematic Observation of Play and Recreation in Communities (SOPARC) was designed to estimate the number and characteristics of people using neighborhood parks by assessing them 4 times/day, 7 days/week. We tested whether this schedule was adequate and determined the minimum number of observations necessary to provide a robust estimate of park user characteristics and their physical activity levels.Methods:We conducted observations every hour for 14 hours per day during 1 summer and 1 autumn week in 10 urban neighborhood parks: 2 each in Los Angeles, CA; Albuquerque, NM; Columbus, OH; Durham, NC; and Philadelphia, PA. We counted park users by gender, age group, apparent race/ethnicity, and activity level. We used a standardized Cronbach’s alpha and intraclass correlation coefficients to test the reliability of using fewer observations.Results:We observed 76,632 individuals, an average of 547/park/day (range 155−786). Interobserver reliability ranged from 0.80 to 0.99. Obtaining a robust estimate of park user characteristics and their physical activity required a schedule of 4 days/week, 4 times/day.Conclusion:An abbreviated schedule of SOPARC was sufficient for estimating park use, park user characteristics, and physical activity. Applying these observation methods can augment physical activity surveillance.

ANEMIA AND TRANSFUSIONS AMONG CRITICALLY ILL PATIENTS ON PROLONGED MECHANICAL VENTILATION

CHEST Journal ◽  
2006 ◽  
Vol 130 (4) ◽  
pp. 212S
Author(s):  
Andrew F. Shorr ◽  
Lee S. Stern ◽  
Monika K. Raut ◽  
Lisa R. Rosenblatt ◽  
Samir Mody ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Prolonged Mechanical Ventilation

Maximal Oxygen Uptake and Daily Physical Activity in 7- to 12-Year-Old Boys

1993 ◽  
Vol 5 (4) ◽  
pp. 357-366 ◽  
Author(s):  
Hazzaa M. Al-Hazzaa ◽  
Mohammed A. Sulaiman
Keyword(s):  
Physical Activity ◽  
Heart Rate ◽  
Oxygen Uptake ◽  
Maximal Oxygen Uptake ◽  
Open Circuit ◽  
Daily Physical Activity ◽  
Activity Level ◽  
Activity Levels ◽  
School Time ◽  
The Relationship

The present study examined the relationship between maximal oxygen uptake (V̇O2max) and daily physical activity in a group of 7- to 12-year-old boys. V̇O2max was assessed through the incremental treadmill test using an open circuit system. Physical activity level was obtained from heart rate telemetry outside of school time for 8 hrs during weekdays and during 40 min of physical education classes. The findings indicated that the absolute value of V̇O2max increased with age, while relative to body weight it remained almost the same across age, with a mean of 48.4 ml · kg−1 · min−1. Moreover, heart rate telemetry showed that the boys spent a limited amount of time on activities that raise the heart rate to a level above 160 bpm (an average of 1.9%). In addition, V̇O2max was found to be significantly related to the percentage of time spent at activity levels at or above a heart rate of 140 bpm, but not with activity levels at or above a heart rate of 160 bpm.

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