scholarly journals Effects of Low-Frequency Cranial Electrostimulation on the Rest-Activity Rhythm and Salivary Cortisol in Alzheimer's Disease

2003 ◽  
Vol 17 (2) ◽  
pp. 101-108 ◽  
Author(s):  
Erik Scherder ◽  
Dirk Knol ◽  
Eus van Someren ◽  
Jan-Berend Deijen ◽  
Rob Binnekade ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Activity Rhythm ◽  
Low Frequency ◽  
Control Group ◽  
Positive Effects ◽  
Alternative Research ◽  
Positive Effect ◽  
Experimental Group ◽  
Rest Activity

Objective. In previous studies, cranial electrostimulation (CES) had positive effects on sleep in depressed patients and in patients with vascular dementia. The present study examined the effects of low-frequency CES on the rest-activity rhythm and cortisol levels of patients with probable Alzheimer's disease (AD). Method. It was hypothesised that a decreased level of cortisol would parallel a positive effect of low-frequency CES on nocturnal restlessness. Sixteen AD patients were randomly assigned to an experimental group (n = 8) or a control group (n = 8). The experimental group was treated with CES, whereas the control group received sham stimulation, for 30 minutes a day, during 6 weeks. The rest-activity rhythm was assessed by actigraphy. Cortisol was measured repeatedly in the saliva throughout the day by means of salivette tubes. Results. Low-frequency CES did not improve the rest-activity rhythm in AD patients. Moreover, both groups showed an increase instead of a decrease in the level of cortisol. Conclusions: These preliminary results suggest that low-frequency CES has no positive effect on the rest-activity rhythm in AD patients. An alternative research design with high-frequency CES in AD is discussed.

scholarly journals Effects of High-Frequency Cranial Electrostimulation on the Rest-Activity Rhythm and Salivary Cortisol in Alzheimer’s Disease

2006 ◽  
Vol 22 (4) ◽  
pp. 267-272 ◽  
Author(s):  
Erik Scherder ◽  
Dirk Knol ◽  
Marie-Jose van Tol ◽  
Eus van Someren ◽  
Jan-Berend Deijen ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Salivary Cortisol ◽  
High Frequency ◽  
Activity Rhythm ◽  
Rest Activity

scholarly journals Selected opportunities for access to geriatric clients from the perspective of assisting professions

2018 ◽  
Vol 9 (1) ◽  
pp. 89-95 ◽  
Author(s):  
Michal Vostrý
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Control Group ◽  
Average Life Expectancy ◽  
The Czech Republic ◽  
People With Dementia ◽  
Information And Communication ◽  
A Minor ◽  
Age Range ◽  
Experimental Group

Aim: The aim of the work was to find out what the influence of ICT use also on ICT (information and communication technology, in this case gaming console with motion sensor, which senses movements of the probanda body and thus is controlled by a fictional figure in the game) in the rehabilitation of cognitive functions on attention and orientation. Concept/methods: Alzheimer's disease is becoming increasingly the source of both professional and lay discourse. Statistical data show that increasing the average life expectancy increases the number of seniors and thus increases the number of people with dementia, with Alzheimer's disease being the most common type (up to 65% of all cases of dementia in the Czech Republic). This trend will continue to follow, and the number of people affected will increase. For guidance in 2006, 2231 people with Alzheimer's disease were registered, while in 2010 this number increased to 3148. For the research, 10 probands (100% of women) were used in the age range of 65-81 years, with the diagnosis of Alzheimer's disease - a light type. Probandi was divided into 5 groups, divided into 5 groups, into an experimental group that actively participated in the intervention and services provided by the institutions in which they were located, and a control group that participated only in the services and activities provided by institution. The research lasted half a year once a week and the activity itself lasted within 25 minutes. Results: Of the 10 probands in total, 5 of us participated actively in our intervention. Prior to the start of the intervention, the results in the assessment (using the Addenbrook Cognitive Assay) were at the same level, but there was visible change between the experimental and the control group during the outcomes assessment. Conclusion: Experimental group achieved better scores or better results. the results themselves stagnated, while the control group experienced a minor deterioration in the test areas.

scholarly journals The Effectiveness of CBTAC Protocol on Burdens of Alzheimer’s Disease on Caregivers and their Sense of Coherence

2020 ◽  
Vol 7 (2) ◽  
pp. 79-87
Author(s):  
Reza Shabahang ◽  
Seyed Javad Emadi ◽  
Farzin Bagheri Sheykhangafshe ◽  
Abbas Ali Hossien Khanzadeh ◽  
Seyedeh Maryam Mousavi
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sense Of Coherence ◽  
Behavioral Treatment ◽  
Analysis Of Covariance ◽  
Effective Intervention ◽  
Control Group ◽  
Cognitive Behavioral Treatment ◽  
The Impact ◽  
Experimental Group

Background: Alzheimer’s disease is predicted to increase dramatically in the near future. Alzheimer’s caregiving brings about severe problems for caregivers. Considering the corrosive consequences of Alzheimer’s disease on Alzheimer’s caregivers, finding an effective intervention is necessary. Thus, the present research conducted by the aim of investigating the effectiveness of cognitive-behavioral treatment for Alzheimer’s disease patients and their caregiver’s protocol on burdens of Alzheimer’s disease on caregivers and their sense of coherence (SOC). Methods: This study was a quasi-experimental research with a pretest-posttest control group design. The target population included all mild Alzheimer’s disease patients and their caregivers referred to the neurology ward of the hospitals in Rasht during summer 2018. According to the medical records and results of screening, 40 mild Alzheimer’s disease, patients and their caregivers recruited by convenience sampling method. After sampling, research participants randomly assigned into two experimental (n= 20) and waitlist control (n=20) groups. The Impact of Alzheimer’s Disease on Caregiver Questionnaire and SOC scale were used to measure the burdens of Alzheimer’s disease on caregivers and caregivers’ SOC. The CBTAC provided for the experimental group participants in 25 sessions of 90-minutes. In the end, the data analyze has done by multivariate analysis of covariance (MANCOVA) and using SPSS24 software. Results: The findings indicated that the CBTAC had a significant effect on the burdens and SOC of Alzheimer’s caregivers in the experimental group (P<0.01). In other words, the CBTAC decreases burdens and increase the SOC of Alzheimer’s caregivers significantly (P<0.01). Conclusion: Based on the research results, the CBTAC is an effective intervention in decreasing caregiving burden and the increasing SOC of Alzheimer’s caregivers. Therefore, CBTAC is a multicomponent intervention that can be used to improve the competency and mental health of Alzheimer’s caregivers.

scholarly journals Effect of Instructionally Embedded Formative Assessment on Students' Motivation to Learn at Higher Education Level

2020 ◽  
Vol V (I) ◽  
pp. 488-499
Author(s):  
Shumaila Hameed ◽  
Mumtaz Akhter
Keyword(s):  
Higher Education ◽  
Formative Assessment ◽  
Undergraduate Students ◽  
Education Level ◽  
Control Group ◽  
Control Group Design ◽  
Positive Effects ◽  
Post Test ◽  
Positive Effect ◽  
Experimental Group

Formative assessment is known for its positive effects it has on students' achievement. This study was designed to find out the effect of formative assessment on students' motivation at the higher education level. This study was experimental in nature; intact pre-test post-test control group design was used for data collection purpose. Sample of the study was selected conveniently, which comprised of undergraduate students. Students belonging to the experimental group were taught with instructional embedded formative assessment, whereas students belonging to the control group were taught with formal teaching methods. Students of both groups were required to fill a motivation questionnaire at the start and end of the study to check the level of intervention. Data collected through pre-test and post-test were analyzed using SPSS. The findings of the current study had suggested that instructional embedded formative assessment had a significant positive effect on students' motivation towards learning at the higher education level.

scholarly journals An Experimental Pilot Study of Global Postural Reeducation Concerning the Cognitive Approach of Patients With Alzheimer’s Disease

2019 ◽  
Vol 35 ◽  
pp. 153331751986782 ◽  
Author(s):  
Jasemin Todri ◽  
Orges Lena ◽  
José Luis Martínez Gil
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Repeated Measures ◽  
Therapeutic Option ◽  
Depression Scale ◽  
Control Group ◽  
Cognitive Approach ◽  
Positive Effects

Background: Several recent studies have examined the positive effects of physical exercise and equilibrium on individuals with neurodegenerative diseases. Objectives: In this sense, this study based on an experimental design, tested whether global postural reeducation (GPR) can affect equilibrium and cognition, life quality, and psychological symptoms of patients with Alzheimer’s disease (AD). Methods: One hundred thirty-five participants with mild and moderate AD diagnosis were assigned to 2 groups: experimental group (EG, n = 90) and control group (CG, n = 45). The GPR therapy was implemented in the EG for 6 months, while both groups underwent neuropsychological assessments prior and after the 6-month period. Results: According to the repeated measures of analysis of variance, significant differences between groups were found at the 6-month follow-up period, in benefit of the EG such as Mini-Mental State Examination ( P = .000), Geriatric Depression Scale ( P = .000), Neuropsychiatric Inventory ( P = .000), quality of life in AD/patient ( P = .000), quality of life in AD/caregivers ( P = .000), Barthel index ( P = .000), and Tinetti Scale ( P = .000), while the CG showed a low performance in the neuropsychological tests. Conclusions: We suggest that GPR is a therapeutic option, which can improve the psychological, physical, and cognitive aspects of patients with AD.

Effects of Melatonin in Two Individuals with Alzheimer's Disease

1998 ◽  
Vol 87 (1) ◽  
pp. 331-339 ◽  
Author(s):  
Girardin Jean-Louis ◽  
Ferdinand Zizi ◽  
Hans Von Gizycki ◽  
Harvey Taub
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Circadian Rhythm ◽  
Aging Process ◽  
Activity Rhythm ◽  
The Other ◽  
Beneficial Effects ◽  
Melatonin Administration ◽  
Activity Cycles ◽  
Rest Activity

Dementia has been associated with circadian rhythm disturbances expressed in several dimensions including body temperature, hormonal concentrations, sleep and wakefulness patterns, and rest-activity cycles. These disturbances may be the result of a dampening in the amplitude of the circadian rhythm. One of the symptoms associated with the aging process has been a decline in the amplitude of the melatonin rhythm. Here, the results of melatonin administration to two patients with Alzheimer's disease are presented. Melatonin administration enhanced and stabilized the circadian rest-activity rhythm in one of the patients along with some reduction of daytime sleepiness and an improvement in mood. The other patient, who was characterized by less cognitive impairment, showed no significant changes associated with melatonin ingestion. Interestingly, the acrophase of rest-activity was delayed for about one hour in both patients. These results suggest that melatonin may have beneficial effects in some patients with Alzheimer's disease

scholarly journals Positive effect of timed blue-enriched white light on sleep and cognition in patients with mild and moderate Alzheimer’s disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Seong Jae Kim ◽  
Sun Hee Lee ◽  
In Bum Suh ◽  
Jae-Won Jang ◽  
Jin Hyeong Jhoo ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sleep Time ◽  
Control Group ◽  
Dim Light ◽  
Sleep And Cognition ◽  
And Behavior ◽  
State Examination ◽  
Positive Effect ◽  
Dark Blue

AbstractConflicting results have been reported regarding the effectiveness of light treatment (LT) in patients with Alzheimer’s disease (AD). We investigated the effectiveness of blue-enriched white LT on sleep, cognition, mood and behavior in patients with mild and moderate AD. The treatment group (n = 14) sat about 60 cm away from a small (136 × 73 × 16 mm) LED light box for 1 h each morning for 2 weeks. The control group (n = 11) wore dark, blue-attenuating sunglasses during the 1 h exposures. The morning light started 9–10 h after each individual’s dim light melatonin onset (DLMO). Assessments were done at baseline (T0), immediate post-treatment (T1), and 4 weeks after the end of the 2 weeks of LT (T2). Sleep was measured by actigraphy. Blue-enriched LT had a significantly better effect on the Pittsburgh Sleep Quality Index at T2 compared to blue-attenuated LT, and a trend of better effectiveness on total sleep time at T2. There was a significant increase in Mini-Mental State Examination score at T2 after blue-enriched LT than that at T0. Our findings suggest that morning blue-enriched LT has a benefit in improving sleep and cognitive function in AD patients.

scholarly journals Circadian rest—activity rhythm disturbances in alzheimer's disease

1996 ◽  
Vol 40 (4) ◽  
pp. 259-270 ◽  
Author(s):  
Eus J.W. van Someren ◽  
Eveline E.O. Hagebeuk ◽  
Cees Lijzenga ◽  
Philip Scheltens ◽  
Sophie E.J.A. de Rooij ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Activity Rhythm ◽  
Rest Activity

scholarly journals LOS CAMBIOS DE PERSONALIDAD EN LA ENFERMEDAD DE ALZHEIMER

2016 ◽  
Vol 5 (1) ◽  
pp. 177
Author(s):  
Charles Rodrigues ◽  
Florencio Vicente Castro ◽  
Cruz Roja Española
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Day Care ◽  
Quantitative Assessment ◽  
Normal Aging ◽  
Personality Inventory ◽  
Cognitive Stimulation ◽  
Control Group ◽  
Experimental Group

Abstract.Previous scientific studies considered the existence of significant differences in the conditions of personality and cognition, in patients with Alzheimer’s disease. The aim of this work was to verify the existence of these differences between patients with Alzheimer’s disease and patients with normal aging. The sample consisted on 231 participants and was divided into two groups, experimental group (EG) with 103 participants with Alzheimer’s disease and a control group (CG), with 128 participants of normal aging. Both groups were subdividing in two subgroups with and without frequency in a day care, rather, with and without cognitive stimulation. The participants were underwent a quantitative assessment based on the application of the MME test and the personality inventory NEO-FFI. Results showed statistically significant differences in all trait of personality, well as in cognition, but it was not possible to establish a pattern of behavior in Alzheimer’s patients.Keywords: Alzheimer, normal aging, personality, cognition.Resumen.Investigaciones científicas anteriores consideran que existen diferencias significativas en las condiciones de cognición y personalidad en enfermos de Alzheimer. El objetivo de este trabajo es verificar la existencia de tales diferencias entre mayores con Alzheimer y mayores en fase de envejecimiento normal. Participaron en esta investigación 231 mayores, divididos por 2 grupos, el grupo experimental (GE) con 103 mayores con diagnóstico clínico de Alzheimer y el grupo de control (GC), con 128 mayores en fase de envejecimiento normal. Ambos grupos fueron subdivididos por 2 subgrupos, con y sin frecuencia en centro de día, es decir, con y sin estimulación cognitiva. Los participantes fueron evaluados a través de la aplicación del test MME y del inventario NEO-FFI. Los resultados presentaron diferencias estadísticamente significativas en todos los trazos de personalidad, bien como en la cognición, pero no fue posible establecer un patrón de comportamiento en los enfermos de Alzheimer.Palabras-clave: Alzheimer, envejecimiento normal, personalidad, cognición.

Sign in / Sign up

Export Citation Format

Share Document