scholarly journals Cerebral Venous Thrombosis: A Tunisian Monocenter Study on 160 Patients

2016 ◽  
Vol 23 (8) ◽  
pp. 1005-1009 ◽  
Author(s):  
Samia Ben Sassi ◽  
Nahla Touati ◽  
Hela Baccouche ◽  
Cyrine Drissi ◽  
Neila Ben Romdhane ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Common Symptom ◽  
Lateral Sinus ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Sagittal Sinus ◽  
Female Predominance

Objective: Data regarding cerebral venous thrombosis in North Africa are scarce. This study aims to identify the clinical features, risk factors, outcome, and prognosis of cerebral venous thrombosis in Tunisia. Methods: Data of 160 patients with radiologically confirmed cerebral venous thrombosis, hospitalized in Mongi Ben Hmida National Institute of Neurology (Tunis, Tunisia), were retrospectively collected and analyzed. Results: The mean age was 37.3 years with a female predominance (83.1%). The mode of onset was subacute in most cases (56.2%). Headache was the most common symptom (71.3%), and focal neurologic symptoms were the main clinical presentation (41.8%). The most common sites of thrombosis were the superior sagittal sinus (65%) and the lateral sinus (60.6%). More than 1 sinus was involved in 114 (71.2%) patients. Parenchymal lesions observed in 85 (53.1%) patients did not correlate with cerebral venous thrombosis extent. Major risk factors were obstetric causes (pregnancy and puerperium) found in 46 (38.6% of women aged <50 years) patients, followed by anemia (28.1%) and congenital or acquired thrombophilia (16.2%). Mortality rate was of 6.6%. Good outcome at 6 months (modified Rankin Scale ≤2) was observed in 105 (87.5%)of 120 patients available for follow-up. Predictors of poor outcome were altered consciousness and elevated plasma C-reactive protein levels. Conclusion: Clinical and radiologic presentation of cerebral venous thrombosis in Tunisia was quite similar to other parts of the world with, however, a particularly high frequency of obstetric causes. Plasma C-reactive protein level should be considered as a prognostic factor in CVT.

Association between diet, lifestyle, metabolic cardiovascular risk factors, and plasma C-reactive protein levels

Metabolism ◽  
2004 ◽  
Vol 53 (11) ◽  
pp. 1436-1442 ◽  
Author(s):  
Gunilla Nordin Fredrikson ◽  
Bo Hedblad ◽  
Jan-Åke Nilsson ◽  
Ragnar Alm ◽  
Göran Berglund ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

scholarly journals Joint evaluation of serum C-Reactive Protein levels and polygenic risk scores as risk factors for schizophrenia

2018 ◽  
Vol 261 ◽  
pp. 148-153 ◽  
Author(s):  
Vishwajit L. Nimgaonkar ◽  
Faith Dickerson ◽  
Jennie G. Pouget ◽  
Kodavali Chowdari ◽  
Colm O’Dushlaine ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Scores ◽  
C Reactive Protein ◽  
Polygenic Risk ◽  
Protein Levels ◽  
Reactive Protein ◽  
Joint Evaluation

scholarly journals SERUM ZINC AND C-REACTIVE PROTEIN LEVELS AS RISK FACTORS FOR MORTALITY IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROME

2018 ◽  
Vol 24 (1) ◽  
pp. 1
Author(s):  
Dwi Retnoningrum ◽  
Banundari Rachmawati ◽  
Dian Widyaningrum
Keyword(s):  
Risk Factors ◽  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Serum Zinc ◽  
Latex Agglutination ◽  
Systemic Inflammatory Response ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

Kondisi Systemic Inflammatory Response Syndrome (SIRS) berkebahyaan terjadinya sepsis dan kegagalan multi organ. Inflamasidapat menyebabkan terjadinya redistribusi zinc ke jaringan sehingga terjadi penurunan kadar zinc plasma. Kadar CRP pada SIRSmeningkat sebagai respons peningkatan protein tahap akut. Tujuan penelitian ini untuk mengetahui apakah kadar zinc dan CRP serummerupakan faktor kebahayaan kematian di pasien SIRS. Penelitian observasional analitik dengan pendekatan kohort prospektif di 30pasien SIRS berusia 27–64 tahun. Kadar zinc serum diperiksa dengan metode atomic absorbance spectrophotometer (AAS) dan CRPserum dengan metode latex agglutination immunoassay menggunakan alat autoanaliser. Kejadian kematian subjek dinilai setelah 28hari perawatan. Data dilakukan uji statistik Chi-Kwadrat, bila tidak memenuhi maka dilakukan uji alternatif Fisher. Besarnya nilaifaktor kebahyaan dilakukan perhitungan kebahayaan relatif. Rerata kadar zinc dan CRP berturut-turut 81,24 ± 8,72 μg/dL, dan 8,13± 8,12 mg/dL. Kematian dalam 28 hari adalah 33,3%. Penelitian ini menunjukkan bahwa kadar zinc plasma < 80 μg/dL bukanmerupakan faktor kebahayaan terjadinya kematian (p=0,114), sedangkan kadar CRP ≥ 10 mg/dL merupakan faktor kebahayaanterjadinya kematian di pasien SIRS (RR=3,28, 95% CI 1,33-8,13, p=0,015). Kadar zinc plasma bukan merupakan faktor kebahayaanterjadinya kematian pada SIRS, sedangkan kadar CRP merupakan faktor kebahayaan terjadinya kematian di pasien SIRS.

Cerebral Venous Thrombosis

2022 ◽  
pp. 113-119
Author(s):  
Ozcan Demetgul
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Clinical Symptoms ◽  
Rare Condition ◽  
Epileptic Seizures ◽  
Lateral Sinus ◽  
Younger Adults ◽  
Sagittal Sinus ◽  
Vital Functions ◽  
Visual Problems

Cerebral venous thrombosis (CVT) is a rare condition involving various symptoms that is mainly seen in younger adults. The most commonly involved are the superior sagittal sinus, lateral sinus, and simoid sinus. About 1% of all ischemic strokes are considered CVT. It is seen 3-fold more in young women. The incidence was estimated to be approx. 1/1000000. Cerebral venous sinuses are superficial and deep spaces, and they have vital functions. There are many symptoms. The most common complaint is headache (89%). Studies reported many different clinical symptoms. Neurological signs including motor and sensorial losses, impaired consciousness, speech disorder, epileptic seizures, visual problems (hemianopia, nystagmus, diplopia, and papilledema), and cranial nerve signs may be seen. The diagnosis is made primarily by suspecting the clinical condition and radiological presentation of thrombosis. The most basic diagnostic method is cranial imaging. Anticoagulants are the main method of treatment. The prognosis has improved over the last years thanks to early diagnosis.

L 028 COMPARISON AMONG SUBCLINICAL ATHEROSCLEROSIS, C-REACTIVE PROTEIN LEVELS AND CLASSICAL RISK FACTORS IN OBESE AND NON OBESE CHILDREN IN CHILE

2007 ◽  
Vol 8 (3) ◽  
pp. 24
Author(s):  
Pilar Arnaiz Gomez ◽  
Mónica Acevedo Blanco ◽  
Salesa Barja Yañez ◽  
Beatriz Guzman Alvarado ◽  
Jacqueline Carvajal Torrealba ◽  
...  
Keyword(s):  
Risk Factors ◽  
Subclinical Atherosclerosis ◽  
Obese Children ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

The role and efficacy of routine high-sensitivity troponin T screening in paediatric COVID-19

2022 ◽  
pp. 1-5
Author(s):  
Mehmet G. Ramoğlu ◽  
Selen Karagözlü ◽  
Özlem Bayram ◽  
Jeyhun Bakhtiyarzada ◽  
Alperen Aydın ◽  
...  
Keyword(s):  
Troponin T ◽  
Myocardial Dysfunction ◽  
High Sensitivity ◽  
Common Symptom ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
High Sensitivity Troponin ◽  
High Sensitivity Troponin T ◽  
Echocardiographic Findings

Abstract Objective: We aimed to evaluate the efficacy and role of high-sensitivity troponin T in children with a confirmed SARS-CoV-2 infection and also the correlation of troponin T levels with symptoms, and echocardiographic findings were analysed. Methods: Two hundred and fourteen patients with a confirmed SARS-CoV-2 infection between the dates of 28 March and 15 August 12020 were enrolled in this retrospective single-centre study. Patients with comorbidities and diagnosed as multisystem inflammatory syndrome in children were excluded. Demographic data, clinical and laboratory parameters were evaluated. The patients were classified and compared according to the troponin positivity. The correlation of troponin T with symptoms and echocardiographic findings was analysed. Results: The most common symptoms in the whole study group were fever (53.3%) and cough (24.8%). Troponin T levels were elevated in 15 (7%) patients. The most common symptom in patients with troponin positivity was also fever (73.3%). Troponin T positivity was significantly higher in patients under the age of 12 months and troponin T levels were negatively correlated with age. C-reactive protein levels were elevated in 77 (36%) of the patients in the whole group and 7 (46.7%) of 15 patients with troponin positivity. C-reactive protein levels were similar between groups. Conclusion: Routine troponin screening does not yield much information in previously healthy paediatric COVID-19 patients without any sign of myocardial dysfunction. Elevated troponin levels may be observed but it is mostly a sign of myocardial injury without detectable myocardial dysfunction in this group of patients.

Serum C-reactive protein levels and body mass index in children and adolescents with CHD

2016 ◽  
Vol 27 (6) ◽  
pp. 1083-1089 ◽  
Author(s):  
Maíra Ribas Goulart ◽  
Daniela Schneid Schuh ◽  
David W. Moraes ◽  
Sandra Mari Barbiero ◽  
Lucia Campos Pellanda
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Children And Adolescents ◽  
Body Mass ◽  
Heart Defects ◽  
Body Mass Index Percentile ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Significant Difference

AbstractBackgroundThe prevalence of overweight in children with CHD is about 26.9%. Increase in adipose tissue is related to the secretion of proinflammatory markers such as C-reactive protein. Assuming that children with CHD are exposed to other inherent risk factors for heart disease, our objective was to evaluate the correlation between levels of C-reactive protein and body mass index in children and adolescents with CHD.MethodsA cross-sectional study with 377 children and adolescents with CHD in a clinical setting of a reference hospital was carried out. C-reactive protein data were collected after 12 hours of fasting. Nutritional status was classified according to body mass index. The patients were divided into three groups: cyanotic, acyanotic, and minimal heart defects (controls).ResultsThe mean age was 9.9±4.2 years, and 53.6% of the sample included males. The cyanotic group represented 22.3%, acyanotic 42.2%, and minimal defects 35.5% of the sample. The average body mass index percentile was 57.23±32.06. The median values of C-reactive protein were as follows: cyanotic 0.340, acyanotic with clinical repercussion 0.203, and minimal defects 0.128. There was a significant difference between the minimal defects and the cyanotic groups (p=0.023). There was a significant correlation between C-reactive protein and body mass index percentile (r=0.293, p<0.01). C-reactive protein levels were higher in girls (p=0.034). There were no significant correlations between C-reactive protein and age or birth weight.ConclusionThe correlation between body mass index percentile and C-reactive protein was confirmed in this population. The prevention of overweight is paramount to avoid overlapping modifiable risk factors to those already inherent to the CHD.

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