scholarly journals Integrated Review of the Association of Cytokines With Fibromyalgia and Fibromyalgia Core Symptoms

2009 ◽  
Vol 11 (4) ◽  
pp. 387-394 ◽  
Author(s):  
Victoria Menzies ◽  
Debra E. Lyon

Fibromyalgia (FMS) is a chronic widespread pain (CWP) and fatigue syndrome that affects three to six million adults in the United States. Core symptoms of FMS include pain, fatigue, and mood and sleep disturbances. To date, consensus has not been reached among researchers regarding the pathogenesis of FMS nor the specific role of cytokine activation on the neuroendocrine—immune response patterns in persons with FMS. The purpose of this article is to describe and synthesize the results of research studies focused on the relationship between cytokines and FMS and among cytokines and core symptoms of FMS. There is some support in the literature for relationships among FMS symptoms and cytokines; however, there are discrepant findings related to whether proinflammatory and anti-inflammatory cytokines are elevated or reduced in persons with FMS and whether their levels correlate with the core symptoms of this disorder. Although the use of cytokine biomarkers must be considered exploratory at this time due to the lack of consistent empirical findings, biobehavioral research focused on understanding the relationship of FMS with cytokines may lead to a better understanding of this complex syndrome. This knowledge may ultimately contribute to the development of interventions for symptom management that address not only the symptom manifestation but also a biological mediator of symptoms.

Author(s):  
Don C. Postema

Understanding the role of ethics committees in providing ethics consultations, ethics education, and ethics-related policies is the context for exploring the relationship of ethics, psychiatry, and religious and spiritual beliefs. After a brief history of biomedical ethics in the United States since the mid-20th century, this chapter presents several case studies that exemplify frequently encountered tensions in these relationships. The central contention is that respecting these beliefs is not equivalent to acquiescing to ethical claims based on them. Rigorous critical reflection and psychiatric insight, coupled with the values embedded in the social practices of healthcare, provide the grounds for evaluating the weight and bearing of religious and spiritual beliefs in ethically complex cases. This is one contribution that ethics committees can make at the intersection of psychiatry and religion.


Author(s):  
Sam Gill

The Proper Study of Religion charts an innovative course of development for the academic study of religion by engaging the legacy of Jonathan Z. Smith (1938–2017), perhaps the field’s most influential and important scholar in the last several decades. Smith was the author’s teacher and mentor for fifty years. Their careers coincided with the explosive expansion of the study of religion in secular universities in the United States beginning in the mid-1960s. Building on Smith’s foundational legacy through creative encounters, the book explores an extensive range of engaging topics, including comparison as essential to academic technique and to human knowledge itself; the important role of experience, richly understood, to both academic studies of religion and to religions as lived; play, philosophically understood, as a core dynamic of Smith’s entire program; the relationship of academic document-based studies to the sensory-rich real world of religions; and self-moving as providing a biological and philosophical foundation on which to develop a proper academic study of religion with expansive potential. The foregrounding of human self-movement, new to the study of religion, is informed by the author’s considerable experience as a dancer and student of dancing in cultures around the world. The Proper Study of Religion honors the remarkable and challenging work of an unforgettable giant of a man while also offering critical assessments and innovative ideas in the effort to advance the remarkable legacy of Jonathan Z. Smith.


Author(s):  
IRWIN GARFINKEL

This article describes existing child support practice in the United States, giving attention to the establishment and enforcement of parental child support obligations as well as to publicly provided child support benefits. Effects of the current system on alleviating poverty are assessed. The article addresses several questions. Should low-income absent parents be excused from the obligation to support their children? Can child support provide more generous benefits to single-parent families while minimizing incentives for the formation of single-parent families? Should children in single-parent families be aided by a welfare program? What are the problems with the current child support system? Finally, a proposal for a new child support insurance system is described, along with estimates of the costs of the system and its effects on poverty and welfare dependence. The relationship of estimated benefits to costs is promising enough to warrant trying out the new system in selected jurisdictions.


Author(s):  
Bradley Curtis A

This chapter considers the status of treaties within the U.S. legal system. The focus is on international agreements concluded through the senatorial advice and consent process specified in Article II of the Constitution. The chapter describes that process, including the Senate’s ability to condition its consent through reservations and other qualifications. It also discusses the role of treaties as supreme law of the land, including the situations in which treaties will be considered “self-executing” and “non–self-executing,” as well as the later-in-time relationship of treaties to federal statutes. The chapter also discusses the relationship of treaties to constitutional limitations concerning the separation of powers and federalism, including the implications of the Supreme Court’s 1920 decision in Missouri v. Holland. The chapter concludes with a consideration of how the United States terminates treaties.


Author(s):  
Bradley Curtis A

This chapter considers the status of treaties within the U.S. legal system. The focus is on international agreements concluded through the senatorial advice-and-consent process specified in Article II of the Constitution. The chapter describes that process, including the Senate’s ability to condition its consent through reservations and other qualifications. It also discusses the role of treaties as supreme law of the land, including the situations in which treaties will be considered “self-executing” and “non–self-executing,” as well as the later-in-time relationship of treaties to federal statutes. The chapter also discusses the relationship of treaties to constitutional limitations concerning the separation of powers and federalism, including the implications of the Supreme Court’s 1920 decision in Missouri v. Holland. The chapter concludes with a consideration of the president’s constitutional authority to withdraw the United States from treaties.


1994 ◽  
Vol 28 (4) ◽  
pp. 261-270 ◽  
Author(s):  
Inese Wheeler

The goal of this study was to explore the relationship of parental bereavement to meaning and purpose in life. Specifically, the study attempted to: 1) investigate the relationship of bereaved parents' perception of purpose in life, and specific parent, child, death, and grief characteristics; and 2) provide descriptive information on the role of meaning in parental bereavement. Two-hundred and three volunteers obtained through Compassionate Friends newsletters in seven cities in various parts of the United States completed a questionnaire consisting of the Purpose in Life Test, the Grief Experience Inventory and questions on meaning. Analysis of the results indicate that lower purpose in life for bereaved parents in this sample is related to less time since the death, loss by suicide, loss of an only child, and loss of more than one child. The descriptive data also indicates that a crisis of meaning may follow the death of a child. Implications for resolution are discussed.


2012 ◽  
Vol 18 (2) ◽  
pp. 263-271 ◽  
Author(s):  
Mei-Yee Ng ◽  
Wing-Sze Wong

This study aimed to examine the possible cross-sectional mediating role of sleep in the relationship of gratitude with depression and anxiety in patients with chronic pain. A total of 224 patients with chronic pain completed structured questionnaires assessing chronic pain, depression and anxiety symptoms, gratitude, and sleep disturbances. Results of multiple regression analyses yielded a modest mediating effect for sleep on the gratitude–depression link whereas a stronger mediating effect was found for sleep on the gratitude–anxiety link. These data show much of the effect of gratitude on depression was direct whereas sleep exerted a stronger mediating effect on the gratitude–anxiety link.


Author(s):  
Steven Conn

This essay examines the rise and role of ethnically specific museums in the United States. It explores the relationship of those museums to the larger questions of how to display American history in museums, how these museums function to create either a national or ethnic identity, and how these museums blur the line between a presentation of “history” and a celebration of “heritage.”


2013 ◽  
Vol 9 (2) ◽  
Author(s):  
Aaron Henry

This article theorizes the relationship of privacy to capital and projects of security and, in doing so, situates privacy in context to pacification. In particular, the article provides an interrogation of the contradictory structuring of privacy as both an object threatened by security and the role of privacy as a means to resist or limit projects of security. Through an analysis of Thomas Hobbes’ writings, this contradictory dual-deployment of privacy is unseated to reveal that far from challenging security, privacy has historically been presupposed and structured by security projects. Moreover, by acclimatizing us to our existence as atomized individuals, alienated from our collective social power, privacy in fact pacifies us. This process is explored through an examination of the Passenger Flight List agreement (PNR) between the United States and EU member states. The article concludes with a brief discussion of the implications of our reliance on privacy has for challenging the logics of security and pacification, especially with the emergent technology of Drones.


2020 ◽  
Vol 17 (6) ◽  
pp. 76-91
Author(s):  
E. D. Solozhentsev

The scientific problem of economics “Managing the quality of human life” is formulated on the basis of artificial intelligence, algebra of logic and logical-probabilistic calculus. Managing the quality of human life is represented by managing the processes of his treatment, training and decision making. Events in these processes and the corresponding logical variables relate to the behavior of a person, other persons and infrastructure. The processes of the quality of human life are modeled, analyzed and managed with the participation of the person himself. Scenarios and structural, logical and probabilistic models of managing the quality of human life are given. Special software for quality management is described. The relationship of human quality of life and the digital economy is examined. We consider the role of public opinion in the management of the “bottom” based on the synthesis of many studies on the management of the economics and the state. The bottom management is also feedback from the top management.


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