The Relation of Physical Activity Changes to Changes in Serum Cholesterol and Body Weight in a Three-Year Follow-up of Population Sample

1981 ◽  
Vol 9 (3) ◽  
pp. 109-117 ◽  
Author(s):  
Jukka T. Salonen ◽  
Jaakko Tuomilehto ◽  
Pekka Puska
1991 ◽  
Vol 11 (2) ◽  
pp. 127-136 ◽  
Author(s):  
Antoine Schranz ◽  
Jaakko Tuomilehto ◽  
Bernard Marti ◽  
R.John Jarrett ◽  
Vilius Grabauskas ◽  
...  

1981 ◽  
Vol 23 (3) ◽  
pp. 545-555 ◽  
Author(s):  
E. A. Dunnington ◽  
J. M. White ◽  
W. E. Vinson

Randomly bred ICR mice were selected for five generations for high and low serum cholesterol (SC), voluntary physical activity, 56-day body weight and feed intake. An unselected, randomly bred control line was maintained with each pair of selection lines. Significant increases in mature body weight occurred in males of high weight and high intake lines and in females of high SC, high weight and high intake lines. Significant decreases in mature body weights occurred in males of low weight line and in females of low SC and low weight lines. Both high and low selected SC lines had greater (P<0.05) activity scores and consumed more feed than the SC control. Mice selected for high activity consumed more (P<0.05) feed than mice selected for low activity. Mice selected for high 56-day body weight consumed more (P<0.05) feed and had higher SC than mice selected for low 56-day body weight. Mice selected for high feed intake were heavier (P<0.05) and more active (P<0.05) than low feed intake mice but had significantly lower SC levels.


Medicines ◽  
2020 ◽  
Vol 7 (9) ◽  
pp. 48
Author(s):  
Chiaki Uehara ◽  
Nobuyuki Miyatake ◽  
Shuhei Hishii ◽  
Hiromi Suzuki ◽  
Akihiko Katayama

Background: Sedentary behavior (SB) is associated with adverse health outcomes. The aim of this study was to clarify seasonal changes in SB including continuous SB (CSB) in community-dwelling Japanese adults. Methods: In this secondary analysis, a total of 65 community-dwelling Japanese adults (7 men and 58 women, 69 (50–78) years) were enrolled. SB (%), including CSB (≥30 min) as well as physical activity, were evaluated using a tri-accelerometer. The differences in these parameters between baseline (summer) and follow-up (winter) were examined. Results: %CSB and %SB at baseline were 20.5 (4.0–60.9) and 54.0 ± 11.5, respectively. CSB was significantly increased (6.6%), and SB was also increased (5.1%) at follow-up compared with baseline. In addition, there were positive relationships between changes in CSB and SB, and body weight and body mass index. Conclusions: These results suggest that there were significant seasonal changes in CSB and SB in community-dwelling Japanese adults.


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Hawazen Atalla ◽  
Bledar Daka ◽  
Ulf Lindblad ◽  
Margareta I Hellgren

Background: Today, more people die because of obesity and it′s comorbidities than due to malnutrition and actions to prevent the development of overweight and obesity is urgently needed. Different measurements, such as body mass index and waist circumference (WC) may develop differently with age and play different roles in the development of cardiovascular and metabolic disease. Objective: The purpose of this study was to examine the development of anthropometric measures in men and women and to identify possible biochemical predictors for at least five percent weight increase over ten years, considering the modifying effect of physical activity. Methods: In the Vara Skövde Cohort, a longitudinal, prospective study, 1327 randomly selected individuals (35-75 years) participated in two examinations, 2002-2005 and 2012-2014. All participants (657 men, 670 women) were carefully examined with body weight and height, WC and fasting venous blood samples. Validated questionnaires about socioeconomic factors and lifestyle were completed. Physical activity was reported on a 4-graded scale and dichotomized into a high and low level of physical activity. Data are analyzed with T-Test and logistic regression and adjusted for age, sex, weight at baseline, smoking, education, physical activity, plasma glucose and triglycerides. Results: Mean age at baseline was 48.8 years. Mean body weight increased till the age of 55 years, 2.4 kg (SD 6.0, P &#8804 0.0001), and decreased significantly thereafter, -1.1 kg (SD 6.3, P= 0.001) without any difference between men and women. Contrary, WC increased continuously over the years in all age-groups, 4 cm (SD 7.4, P &#8804 0.001). Further, no normal weight person became obese at follow- up. Individuals who maintained or increased their level of physical activity to high had a significantly lower risk for weight increase as compared to those who remained or decreased their level of physical activity to a low level (OR 0.7, CI 0.7 - 0.9, P= 0.008). Serum concentration of LDL (low density lipoprotein) was inversely associated with 5% weight increase after ten years (OR 0.7, CI 0.6-0.7, P &#8804 0.001). We did not find that education level, psychological stress or sleep quality at baseline predicted body weight change. Conclusion: While body weight peaked at the age of 55 years, abdominal obesity increased continuously during the follow-up time. Maintained physical activity seems to limit this increase and emphasizes the importance of a high level of physical activity over the years. The risk of a low concentration of LDL for weight gain needs to be further examined.


Author(s):  
Bárbara de Barros Gonze ◽  
Thatiane Lopes Valentim Di Paschoale Ostolin ◽  
Evandro Fornias Sperandio ◽  
Rodolfo Leite Arantes ◽  
Marcello Romiti ◽  
...  

Background: Sedentary behavior (SB) is an independent risk factor for cardiovascular diseases. We hypothesized that there may be benefits of replacing SB with light-intensity (LIPA) and moderate-to-vigorous (MVPA) physical activity. Substituting SB with LIPA and MVPA might be associated with body composition changes. Methods: We assessed body weight, body mass index (BMI), fat body mass (FBM), and physical activity level, as well as one-year changes, in 780 adults (EPIMOV Study). Results: We analyzed into 10-min blocks SB, LIPA, MVPA, and total wear time. After 14 ± 3 months of follow-up, there were 242 completed procedures. We reallocated time spent in SB to LIPA or MVPA and assessed cross-sectional and prospective associations with the outcomes using isotemporal substitution models. In cross-sectional analysis, substituting 10-min blocks of SB with MVPA led to significant decreases of 1.23 kg in body weight, 0.30 kg/m² in BMI, and 0.38% in FBM. 10-min blocks substituting SB with LIPA produced significantly lower body weight (1 kg) and BMI (0.1 kg/m²) values. In longitudinal analysis, reallocating SB to MVPA was only associated with FBM decline (−0.31%). Conclusions: Substituting SB with MVPA is associated with significant improvement in obesity indices in both cross-sectional and follow-up. Replacing SB with LIPA produced a less consistent impact.


2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Rebecca A. Seguin ◽  
Sara C. Folta ◽  
Miriam E. Nelson ◽  
Karla L. Hanson ◽  
Andrea Z. LaCroix

Background. The repeated loss and regain of body weight, referred to as weight cycling, may be associated with negative health complications. Given today’s obesity epidemic and related interventions to address obesity, it is increasingly important to understand contexts and factors associated with weight loss maintenance. This study examined BMI among individuals who had previously participated in a 12-week, evidence-based, nationally disseminated nutrition and physical activity program designed for overweight and obese middle-aged and older women.Methods. Data were collected using follow-up surveys. Complete height and weight data were available for baseline, 12-week program completion (post-program) and follow-up (approximately 3 years later) for 154 women (response rate = 27.5%; BMI characteristics did not differ between responders and nonresponders).Results. Mean BMI decreased significantly from baseline to post-program (−0.5,P<0.001) and post-program to follow-up (−0.7,P<0.001). Seventy-five percent of survey respondents maintained or decreased BMI post-program to follow-up. Self-efficacy and social support for healthy eating behaviors (but not physical activity) were associated with BMI maintenance or additional weight loss.Conclusions. These findings support the durability of weight loss following participation in a relatively short-term intervention.


1981 ◽  
Vol 23 (3) ◽  
pp. 533-544 ◽  
Author(s):  
E. A. Dunnington ◽  
J. M. White ◽  
W. E. Vinson

A five-generation selection experiment was conducted with randomly bred ICR mice. Lines were developed for high (CH) and low (CL) serum cholesterol (SC), voluntary physical activity (lines AH and AL), 56-day body weight (lines WH and WL), and feed intake (lines IH and IL). An unselected randomly bred control line was maintained with each pair of selection lines (CC, AC, WC and IC, respectively). Selection was based on individual performance in SC, activity and weight lines, and on within-sex, among full-sib family selection in intake lines. Genetic responses (selected line generation means deviated from control line generation means and regressed on generation number) were different from zero (P<0.05) in CH males and females, CL males, AH males and females, AL males, WH males and females, WL males and females, and IH females. Realized heritabilities which did not differ (P<0.05) between sexes were: 0.43±0.05 (line CH), 0.37±0.06 (line CL), 0.26±0.08 (line AH), 0.16±0.04 (line AL), 0.33±0.05 (line WH), 0.40±0.05 (line WL), 0.42±0.06 (line IH). In Line IL heritabilities of males and females differed (P<0.05) from each other (0.08±0.06 and 0.29±0.06, respectively).


2020 ◽  
Vol 4 (5) ◽  
pp. 308-313
Author(s):  
V.A. Akhmedov ◽  
◽  
A.S. Gudim ◽  

Obesity and its concomitant diseases preserve to be an urgent problem of modern medicine, as they are widespread worldwide and lead to negative medical, social and economic consequences that damage both patients and the state. The article presents statistical data reflecting the situation of obesity in Russia, describes the risk factors of obesity, highlights modern methods to follow-up of patients with obesity (e.g., correction of lifestyle and nutrition with the calorie control, change in physical activity, the use of pharmacological drugs and conducting various types of bariatric interventions). It is noted that the key factors that prevent the obesity development and control the body weight are rational nutrition (taking into account individual health problem), compliance with the principles of moderation, diversity, and dietary intake. Besides, it may be useful to practice wellness techniques (e.g., callanetics), which help to reduce and normalize body weight and develop concentration and stress tolerance. Special attention is paid to the obesity effect on the course of COVID-19 infection, which causes higher susceptibility and the development of severe complications. KEYWORDS: obesity, overweight, risk factor, rational nutrition, diet, physical activity. FOR CITATION: Akhmedov V.A., Gudim A.S. Modern methods to follow-up of obese patient. Russian Medical Inquiry. 2020;4(5):308–313. DOI: 10.32364/2587-6821-2020-4-5-308-313.


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