Logic Learning Machine and standard supervised methods for Hodgkin’s lymphoma prognosis using gene expression data and clinical variables

2016 ◽  
Vol 24 (1) ◽  
pp. 54-65 ◽  
Author(s):  
Stefano Parodi ◽  
Chiara Manneschi ◽  
Damiano Verda ◽  
Enrico Ferrari ◽  
Marco Muselli
Keyword(s):  
Gene Expression ◽  
Machine Learning ◽  
Support Vector Machine ◽  
Decision Tree ◽  
Hodgkin’S Lymphoma ◽  
Hodgkin's Lymphoma ◽  
Support Vector ◽  
Expression Data ◽  
Clinical Variables ◽  
Learning Machine

This study evaluates the performance of a set of machine learning techniques in predicting the prognosis of Hodgkin’s lymphoma using clinical factors and gene expression data. Analysed samples from 130 Hodgkin’s lymphoma patients included a small set of clinical variables and more than 54,000 gene features. Machine learning classifiers included three black-box algorithms ( k-nearest neighbour, Artificial Neural Network, and Support Vector Machine) and two methods based on intelligible rules (Decision Tree and the innovative Logic Learning Machine method). Support Vector Machine clearly outperformed any of the other methods. Among the two rule-based algorithms, Logic Learning Machine performed better and identified a set of simple intelligible rules based on a combination of clinical variables and gene expressions. Decision Tree identified a non-coding gene ( XIST) involved in the early phases of X chromosome inactivation that was overexpressed in females and in non-relapsed patients. XIST expression might be responsible for the better prognosis of female Hodgkin’s lymphoma patients.

scholarly journals Encrypted DNP3 Traffic Classification Using Supervised Machine Learning Algorithms

2019 ◽  
Vol 1 (1) ◽  
pp. 384-399 ◽  
Author(s):  
Thais de Toledo ◽  
Nunzio Torrisi
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Decision Tree ◽  
Smart Grids ◽  
Learning Algorithms ◽  
Electric Utility ◽  
Machine Learning Algorithms ◽  
Supervised Machine Learning ◽  
Support Vector ◽  
Communication Link

The Distributed Network Protocol (DNP3) is predominately used by the electric utility industry and, consequently, in smart grids. The Peekaboo attack was created to compromise DNP3 traffic, in which a man-in-the-middle on a communication link can capture and drop selected encrypted DNP3 messages by using support vector machine learning algorithms. The communication networks of smart grids are a important part of their infrastructure, so it is of critical importance to keep this communication secure and reliable. The main contribution of this paper is to compare the use of machine learning techniques to classify messages of the same protocol exchanged in encrypted tunnels. The study considers four simulated cases of encrypted DNP3 traffic scenarios and four different supervised machine learning algorithms: Decision tree, nearest-neighbor, support vector machine, and naive Bayes. The results obtained show that it is possible to extend a Peekaboo attack over multiple substations, using a decision tree learning algorithm, and to gather significant information from a system that communicates using encrypted DNP3 traffic.

scholarly journals Comparison of Support Vector Machine, Bayesian Logistic Regression, and Alternating Decision Tree Algorithms for Shallow Landslide Susceptibility Mapping along a Mountainous Road in the West of Iran

2020 ◽  
Vol 10 (15) ◽  
pp. 5047 ◽  
Author(s):  
Viet-Ha Nhu ◽  
Danesh Zandi ◽  
Himan Shahabi ◽  
Kamran Chapi ◽  
Ataollah Shirzadi ◽  
...  
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Logistic Regression ◽  
Decision Tree ◽  
Shallow Landslide ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Svm Algorithm ◽  
Alternating Decision Tree ◽  
Bayesian Logistic Regression

This paper aims to apply and compare the performance of the three machine learning algorithms–support vector machine (SVM), bayesian logistic regression (BLR), and alternating decision tree (ADTree)–to map landslide susceptibility along the mountainous road of the Salavat Abad saddle, Kurdistan province, Iran. We identified 66 shallow landslide locations, based on field surveys, by recording the locations of the landslides by a global position System (GPS), Google Earth imagery and black-and-white aerial photographs (scale 1: 20,000) and 19 landslide conditioning factors, then tested these factors using the information gain ratio (IGR) technique. We checked the validity of the models using statistical metrics, including sensitivity, specificity, accuracy, kappa, root mean square error (RMSE), and area under the receiver operating characteristic curve (AUC). We found that, although all three machine learning algorithms yielded excellent performance, the SVM algorithm (AUC = 0.984) slightly outperformed the BLR (AUC = 0.980), and ADTree (AUC = 0.977) algorithms. We observed that not only all three algorithms are useful and effective tools for identifying shallow landslide-prone areas but also the BLR algorithm can be used such as the SVM algorithm as a soft computing benchmark algorithm to check the performance of the models in future.

scholarly journals Modelos de machine learning para predição do sucesso de startups

2021 ◽  
Vol 12 (2) ◽  
pp. 28-55
Author(s):  
Fabiano Rodrigues ◽  
Francisco Aparecido Rodrigues ◽  
Thelma Valéria Rocha Rodrigues
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Random Forest ◽  
Decision Tree ◽  
Initial Public Offering ◽  
Gradient Boosting ◽  
Support Vector ◽  
Trade Offs ◽  
Extreme Gradient Boosting ◽  
Public Offering

Este estudo analisa resultados obtidos com modelos de machine learning para predição do sucesso de startups. Como proxy de sucesso considera-se a perspectiva do investidor, na qual a aquisição da startup ou realização de IPO (Initial Public Offering) são formas de recuperação do investimento. A revisão da literatura aborda startups e veículos de financiamento, estudos anteriores sobre predição do sucesso de startups via modelos de machine learning, e trade-offs entre técnicas de machine learning. Na parte empírica, foi realizada uma pesquisa quantitativa baseada em dados secundários oriundos da plataforma americana Crunchbase, com startups de 171 países. O design de pesquisa estabeleceu como filtro startups fundadas entre junho/2010 e junho/2015, e uma janela de predição entre junho/2015 e junho/2020 para prever o sucesso das startups. A amostra utilizada, após etapa de pré-processamento dos dados, foi de 18.571 startups. Foram utilizados seis modelos de classificação binária para a predição: Regressão Logística, Decision Tree, Random Forest, Extreme Gradiente Boosting, Support Vector Machine e Rede Neural. Ao final, os modelos Random Forest e Extreme Gradient Boosting apresentaram os melhores desempenhos na tarefa de classificação. Este artigo, envolvendo machine learning e startups, contribui para áreas de pesquisa híbridas ao mesclar os campos da Administração e Ciência de Dados. Além disso, contribui para investidores com uma ferramenta de mapeamento inicial de startups na busca de targets com maior probabilidade de sucesso.   

Comparison between support vector machine and deep learning, machine-learning technologies for detecting epiretinal membrane using 3D-OCT

2018 ◽  
Vol 39 (8) ◽  
pp. 1871-1877 ◽  
Author(s):  
Tomoaki Sonobe ◽  
Hitoshi Tabuchi ◽  
Hideharu Ohsugi ◽  
Hiroki Masumoto ◽  
Naohumi Ishitobi ◽  
...  
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Deep Learning ◽  
Epiretinal Membrane ◽  
Learning Technologies ◽  
Support Vector ◽  
Learning Machine

A Hybrid Kernel Extreme Learning Machine and Improved Cat Swarm Optimization for Microarray Medical Data Classification

2020 ◽  
pp. 779-814
Author(s):  
S. Chakravarty ◽  
R. Bisoi ◽  
P. K. Dash
Keyword(s):  
Gene Expression ◽  
Support Vector Machine ◽  
Extreme Learning Machine ◽  
Medical Data ◽  
Support Vector ◽  
Swarm Optimization ◽  
Cat Swarm Optimization ◽  
Kernel Extreme Learning Machine ◽  
Learning Machine ◽  
Small Sample Sizes

This paper presents the pattern classification of the binary microarray gene expression based medical data using extreme learning machine (ELM) and its variants like on-line sequential ELM (OSELM) and kernel based extreme learning machine (KELM). In the KELM category two variants namely the wavelet based kernel (WKELM) extreme learning machine and radial basis kernel extreme learning machine (RKELM) along with support vector machine (SVMRBF) and support vector machine polynomial (SVMPoly) are used to classify microarray medical datasets. Further to reduce the high dimensionality of Microarray medical datasets giving rise to high number of gene expression and small sample sizes, a modified evolutionary cat swarm optimization (MCSO) technique is adopted. The efficiency of the proposed algorithm is verified using a set of performance metrics for four binary medical datasets belonging to breast cancer, prostate cancer, colon tumor, and leukemia, respectively.

scholarly journals Spatial–Temporal Analysis of Land Cover Change at the Bento Rodrigues Dam Disaster Area Using Machine Learning Techniques

2019 ◽  
Vol 11 (21) ◽  
pp. 2548
Author(s):  
Dong Luo ◽  
Douglas G. Goodin ◽  
Marcellus M. Caldas
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Land Cover ◽  
Decision Tree ◽  
Machine Learning Algorithms ◽  
Training Data ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Disaster Area ◽  
Mine Sites

Disasters are an unpredictable way to change land use and land cover. Improving the accuracy of mapping a disaster area at different time is an essential step to analyze the relationship between human activity and environment. The goals of this study were to test the performance of different processing procedures and examine the effect of adding normalized difference vegetation index (NDVI) as an additional classification feature for mapping land cover changes due to a disaster. Using Landsat ETM+ and OLI images of the Bento Rodrigues mine tailing disaster area, we created two datasets, one with six bands, and the other one with six bands plus the NDVI. We used support vector machine (SVM) and decision tree (DT) algorithms to build classifier models and validated models performance using 10-fold cross-validation, resulting in accuracies higher than 90%. The processed results indicated that the accuracy could reach or exceed 80%, and the support vector machine had a better performance than the decision tree. We also calculated each land cover type’s sensitivity (true positive rate) and found that Agriculture, Forest and Mine sites had higher values but Bareland and Water had lower values. Then, we visualized land cover maps in 2000 and 2017 and found out the Mine sites areas have been expanded about twice of the size, but Forest decreased 12.43%. Our findings showed that it is feasible to create a training data pool and use machine learning algorithms to classify a different year’s Landsat products and NDVI can improve the vegetation covered land classification. Furthermore, this approach can provide a venue to analyze land pattern change in a disaster area over time.

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