Clinician's Corner: Osteoarthritis: A Lifestyle Medicine Assessment of Risks, Prevention, and Treatment

2007 ◽  
Vol 1 (4) ◽  
pp. 256-259
Author(s):  
Clinton L. Greenstone
Keyword(s):  
Knee Injury ◽  
Country Risk ◽  
Musculoskeletal Health ◽  
Lifestyle Medicine ◽  
Sports Involvement ◽  
Increased Risk ◽  
Strengthening Exercises ◽  
History Of ◽  
High Level ◽  
Risks Prevention

The prevalence of symptomatic osteoarthritis after the age of 55 years ranges from about 30% to 50% in men and 40% to 60% in women. With the increasing age of the population, it is estimated that in 20 years, osteoarthritis will be the fourth leading cause of disability in this country. Risk factors for osteoarthritis include previous knee surgery, occupational bending and lifting, knee injury, and obesity. Many have suggested that recreational activity and high-level sports involvement are associated with increased risk of osteoarthritis. Although high-impact exercises increase the risk of osteoarthritis, physicians need to still recommend appropriate lower impact aerobic exercise and strengthening exercises for all of our patients to improve their general health, including cardiovascular and musculoskeletal health. Clearly, more research is needed to help us understand how to modify the natural history of this condition in more stringent evidence-based fashion. However, lifestyle medicine approaches combined with conventional therapies are effective in decreasing the disability associated with chronic osteoarthritis.

scholarly journals Evaluation of factor VIII value in normal women and whom encountered recurrent pregnancy loss: is there any significant difference?

2020 ◽  
Vol 9 (3) ◽  
pp. 1034
Author(s):  
Douaa Al Rez ◽  
Hasan Naser Eldine ◽  
Marwan Alhalabi
Keyword(s):  
Factor Viii ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Fetal Loss ◽  
Control Group ◽  
Increased Risk ◽  
Significant Difference ◽  
History Of ◽  
Normal Women ◽  
High Level

Background: Recurrent pregnancy loss (RPL) is a serious problem on the women, it defined as two or more consecutive pregnancy losses before the fetus has reached birth. The aim of this study is to evaluate the association between the elevation in the factor VIII and RPL. Because women who have thrombophilia have increased risk of fetal loss in most studies.Methods: A total 72 women were recruited in this case control study. They divided into two groups: the RPL group included 41 women with a history of recurrent pregnancy loss and the control group included 31 healthy women, who had at least one successful pregnancy and none of them had a history of fetal loss or complicated pregnancy.Results: A majority of the patients of this study didn't have a high level of factor VIII, 9 of 41 (22%) patients of RPL group in comparison with 21 of 32 (65,6%) of control group, that suffer from the increase rate of FVIII, this means that factor VIII doesn't effect on RPL.Conclusions: The present study showed that the serum elevation in the factor VIII is not significantly associated with RPL.

scholarly journals Assessment of SARS-CoV-2 Infection among Healthcare Workers of a German COVID-19 Treatment Center

2021 ◽  
Vol 18 (13) ◽  
pp. 7057
Author(s):  
Lionel Larribère ◽  
Jelizaveta Gordejeva ◽  
Lisa Kuhnhenn ◽  
Maximilian Kurscheidt ◽  
Monika Pobiruchin ◽  
...  
Keyword(s):  
Early Phase ◽  
Healthcare Workers ◽  
Treatment Center ◽  
Patient Exposure ◽  
Increased Risk ◽  
History Of ◽  
High Level ◽  
Low Prevalence

To date, more than 160 million people have been infected with COVID-19 worldwide. In the present study, we investigated the history of SARS-CoV-2 infection among 3067 healthcare workers (HCW) in a German COVID-19 treatment center during the early phase of the pandemic (July 2020) based on the seroprevalence of SARS-CoV-2 antibodies and self-reported previous PCR results. The results demonstrate a low prevalence of SARS-CoV-2 infection (n = 107 [3.5%]) with no increased risk for employees with a high level of patient exposure in general or working in COVID-19-confined areas in particular. This suggests that the local hygiene standards implemented in our hospital during the first wave of COVID-19 pandemic were effective in preventing patient-to-HCW transmission. No evidence for highly mobile staff serving as a vector for SARS-CoV-2 transmission could be found. In addition, impairment of smell and/or taste was strongly associated with SARS-CoV-2 history.

High-Density Lipoprotein-Cholesterol Subfractions in Adolescent Twins

PEDIATRICS ◽  
1987 ◽  
Vol 79 (2) ◽  
pp. 181-189
Author(s):  
Joann N. Bodurtha ◽  
Richard Schieken ◽  
Jere Segrest ◽  
Walter E. Nance
Keyword(s):  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
Cardiovascular Death ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Increased Risk ◽  
History Of ◽  
High Level ◽  
Adolescent Twins

Data on the levels of high-density lipoprotein-cholesterol (HDL-C) and subfractions in 102 adolescent twin pairs and their parents are presented. Children with a family history of premature cardiovascular death had lower levels of HDL2-C than did those without such a history. White girls reporting a high level of physical activity had higher levels of HDL-C and HDL2-C than did their more sedentary peers. In general, children of mothers who smoked had lower HDL2-C than did children of nonsmoking mothers. These findings suggest that low levels of HDL2-C in children may identify families in which there is an increased risk of coronary heart disease and that parental smoking may contribute to changes in this risk factor in the children of smokers as well as in the smokers themselves.

scholarly journals Knee Pain and a Prior Injury Are Associated with Increased Risk of a New Knee Injury: Data from the Osteoarthritis Initiative

2015 ◽  
Vol 42 (8) ◽  
pp. 1463-1469 ◽  
Author(s):  
Jeffrey B. Driban ◽  
Grace H. Lo ◽  
Charles B. Eaton ◽  
Lori Lyn Price ◽  
Bing Lu ◽  
...  
Keyword(s):  
Knee Pain ◽  
Knee Injury ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Knee Injuries ◽  
Contralateral Knee ◽  
Increased Risk ◽  
History Of ◽  
Osteoarthritis Initiative ◽  
Prior Injury

Objective.We explored whether knee pain or a history of knee injury were associated with a knee injury in the following 12 months.Methods.We conducted longitudinal knee-based analyses among knees in the Osteoarthritis Initiative. We included both knees of all participants who had at least 1 followup visit with complete data. Our first sets of exposures were knee pain (chronic knee symptoms and severity) at baseline, 12-month, 24-month, and 36-month visits. Another exposure was a history of injury that we defined as a self-reported injury at any time prior to baseline, 12-month, 24-month, or 36-month visit. The outcome was self-reported knee injury during the past year at 12-month, 24-month, 36-month, and 48-month visits. We evaluated the association between ipsilateral and contralateral knee pain or history of injury and a new knee injury within 12 months of the exposure using generalized linear mixed model for repeated binary outcomes.Results.A knee with reported chronic knee symptoms or ipsilateral or contralateral history of an injury was more likely to experience a new knee injury in the following 12 months than a knee without chronic knee symptoms (OR 1.84, 95% CI 1.57–2.16) or prior injury (prior ipsilateral knee injury: OR 1.81, 95% CI 1.56–2.09. Prior contralateral knee injury: OR 1.43, 95% CI 1.23–1.66).Conclusion.Knee pain and a history of injury are associated with new knee injuries. It may be beneficial for individuals with knee pain or a history of injury to participate in injury prevention programs.

scholarly journals Prevalence of Knee Injury in East Java’s Puslatda Fencing Athletes

2021 ◽  
Vol 3 (2) ◽  
pp. 77
Author(s):  
Farah Yusrania ◽  
Damayanti Tinduh ◽  
Dwikora Novembri Utomo ◽  
Lilik Herawati
Keyword(s):  
High Risk ◽  
Knee Injury ◽  
Knee Injuries ◽  
Risk Profile ◽  
Training Center ◽  
Injury Site ◽  
Sports Events ◽  
Risk Of Injury ◽  
Strengthening Exercises ◽  
History Of

Background: Fencing is one of many sports that are held in major sports events, both nationally and internationally. Fencing also has a high risk of injury, and knee injury is the most common injury site according to the authors' observations. Even so, studies on knee injuries in fencing athletes are very scarce, especially in Indonesia.Aim: To ascertain the prevalence of knee injuries and its intrinsic risk profile in fencing athletes at East Java Puslatda (regional training center).Material and Methods: The method used in this study was descriptive observational based on athletes’ health screening data, which were obtained from Sport Clinic Dr. Soetomo Academic General Hospital and athletes’ fitness data obtained from KONI.Results: This research involved 14 fencing athletes that were active in the East Java regional training center. Out of the 14 athletes who were included in this study, it was found that 1 athlete (7.1%) had a knee injury and 13 athletes (92.9%) had no knee injury. The athlete who had injured was a senior overweight female, had history of knee injury, average VO2max, normal knee ROM and alignment, and did 1-2 times leg strengthening exercises every week.Conclusion: The prevalence of knee injuries in fencing athletes at East Java regional training center is 1 in 14 athletes.

The Survivor Moms’ Companion: Feasibility, Safety, and Acceptability of a Posttraumatic Stress Specific Psychoeducation Program for Pregnant Survivors of Childhood Maltreatment and Sexual Trauma

2011 ◽  
Vol 1 (2) ◽  
pp. 122-135 ◽  
Author(s):  
Mickey Sperlich ◽  
Julia S. Seng ◽  
Heather Rowe ◽  
Heather Cameron ◽  
Anna Harris ◽  
...  
Keyword(s):  
Posttraumatic Stress ◽  
Childhood Maltreatment ◽  
Self Report ◽  
Abuse Survivors ◽  
Increased Risk ◽  
Self Study ◽  
Women Abuse ◽  
Symptom Level ◽  
History Of ◽  
High Level

Pregnant women with history of abuse and posttraumatic stress disorder (PTSD) have increased risk of adverse mental health and childbearing outcomes. The Survivor Moms’ Companion (SMC) is a psychoeducation program designed to meet the needs of women abuse survivors affected by PTSD during the childbearing year. This article reports on the feasibility, safety, and acceptability findings of an open pilot. Participants completed 10 self-study modules and structured tutoring sessions, and completed self-report measures, including reports of tutor fidelity to the manual, repeated assessment of PTSD symptoms, Subjective Units of Disturbance (SUD) scores, and evaluation interviews. Results indicate that the intervention can be implemented within low-resource settings with high level of fidelity to the manual. Monitoring of PTSD symptom level and distress indicate that the intervention is safe. Participants report satisfaction with the format and content and appreciation for the tutoring component. The SMC appears to be feasible, safe, and acceptable.

A Confrontation between Two Doctrines: The Birth of Struggle for Hegemony in Hebrew Children's Literature during the 1930s and 1940s

2008 ◽  
Vol 1 (2) ◽  
pp. 139-155 ◽  
Author(s):  
YAEL DARR
Keyword(s):  
Children's Literature ◽  
Educational System ◽  
Single Channel ◽  
Children’S Literature ◽  
The Political ◽  
Literary Creation ◽  
History Of ◽  
High Level ◽  
First Time ◽  
Literary Quality

This article describes a crucial and fundamental stage in the transformation of Hebrew children's literature, during the late 1930s and 1940s, from a single channel of expression to a multi-layered polyphony of models and voices. It claims that for the first time in the history of Hebrew children's literature there took place a doctrinal confrontation between two groups of taste-makers. The article outlines the pedagogical and ideological designs of traditionalist Zionist educators, and suggests how these were challenged by a group of prominent writers of adult poetry, members of the Modernist movement. These writers, it is argued, advocated autonomous literary creation, and insisted on a high level of literary quality. Their intervention not only dramatically changed the repertoire of Hebrew children's literature, but also the rules of literary discourse. The article suggests that, through the Modernists’ polemical efforts, Hebrew children's literature was able to free itself from its position as an apparatus controlled by the political-educational system and to become a dynamic and multi-layered field.

Dental Implant Placement in Patients with a History of Medications Related to Osteonecrosis of the Jaws: A Systematic Review

2020 ◽  
Author(s):  
Judd Sher ◽  
Kate Kirkham-Ali ◽  
Denny Luo ◽  
Catherine Miller ◽  
Dileep Sharma
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Drug Therapy ◽  
Dental Implant ◽  
Case Series ◽  
Cochrane Central Register ◽  
Bisphosphonate Treatment ◽  
Implant Placement ◽  
Increased Risk ◽  
History Of

The present systematic review evaluates the safety of placing dental implants in patients with a history of antiresorptive or antiangiogenic drug therapy. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed. PubMed, Cochrane Central Register of Controlled Trials, Scopus, Web of Science, and OpenGrey databases were used to search for clinical studies (English only) to July 16, 2019. Study quality was assessed regarding randomization, allocation sequence concealment, blinding, incomplete outcome data, selective outcome reporting, and other biases using a modified Newcastle-Ottawa scale and the Joanna Briggs Institute critical appraisal checklist for case series. A broad search strategy resulted in the identification of 7542 studies. There were 28 studies reporting on bisphosphonates (5 cohort, 6 case control, and 17 case series) and one study reporting on denosumab (case series) that met the inclusion criteria and were included in the qualitative synthesis. The quality assessment revealed an overall moderate quality of evidence among the studies. Results demonstrated that patients with a history of bisphosphonate treatment for osteoporosis are not at increased risk of implant failure in terms of osseointegration. However, all patients with a history of bisphosphonate treatment, whether taken orally for osteoporosis or intravenously for malignancy, appear to be at risk of ‘implant surgery-triggered’ MRONJ. In contrast, the risk of MRONJ in patients treated with denosumab for osteoporosis was found to be negligible. In conclusion, general and specialist dentists should exercise caution when planning dental implant therapy in patients with a history of bisphosphonate and denosumab drug therapy. Importantly, all patients with a history of bisphosphonates are at risk of MRONJ, necessitating this to be included in the informed consent obtained prior to implant placement. The James Cook University College of Medicine and Dentistry Honours program and the Australian Dental Research Foundation Colin Cormie Grant were the primary sources of funding for this systematic review.

Family History of Diabetes Is Associated with Increased Risk of Recurrent DKA in Pediatric Patients in Rhode Island

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1378-P
Author(s):  
JANAKI D. VAKHARIA ◽  
SUNGEETA AGRAWAL ◽  
JANINE BACIC ◽  
LISA S. TOPOR
Keyword(s):  
Family History ◽  
Rhode Island ◽  
Pediatric Patients ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
History Of

A New Step in the Study of the History of the Russian Prosecutor’s Office

2019 ◽  
pp. 94-98
Keyword(s):  
Russian Federation ◽  
Russian Empire ◽  
Practical Significance ◽  
History Of ◽  
The Russian Federation ◽  
The Russian Empire ◽  
High Level ◽  
The University

The paper is a review on the textbook by A. V. Yeremin, «The History of the National Prosecutor’s office» and the anthology «The Prosecutor’s Office of the Russian Empire in the Documents of 1722–1917» (authors: V. V. Lavrov, A. V. Eremin, edited by N. M. Ivanov) published at the St. Petersburg Law Institute (branch) of the University of the Prosecutor’s office of the Russian Federation in 2018. The reviewers emphasize the high relevance and high level of research, their theoretical and practical significance. The textbook and the anthology will help the students increase their legal awareness, expand their horizons.

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