Astrotricoumarin, an antiproliferative 4′-hydroxy-2′,3′-dihydroprenylated methylcoumarin from an Astrotrichilia sp. from the Madagascar dry forest[1]
2011 ◽
Vol 6
(9)
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pp. 1934578X1100600
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Keyword(s):
2D Nmr
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Bioassay guided fractionation of the ethanol extract of a new endemic species of the genus Astrotrichilia led to the isolation of the new antiproliferative 3-(4′-hydroxy-2′,3′-dihydroprenyl)-4,6-dimethoxy-5-methylcoumarin, named astrotricoumarin (8) with an IC50 value of 6.8 μM against the A2780 cell line. The structure of compound 8 was elucidated on the basis of its physical and spectroscopic data, including extensive 1D- and 2D-NMR analysis.
2012 ◽
Vol 7
(6)
◽
pp. 1934578X1200700
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2015 ◽
Vol 96
◽
pp. 209-217
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Keyword(s):
2016 ◽
Vol 11
(6)
◽
pp. 1934578X1601100
2015 ◽
Vol 10
(9)
◽
pp. 1934578X1501000
◽
2021 ◽
Keyword(s):