Tobacco Smoking and the Association With First Incidence of Mood, Anxiety, and Substance Use Disorders: A 3-Year Prospective Population-Based Study

2021 ◽  
pp. 216770262095928
Author(s):  
Karin Monshouwer ◽  
Margreet ten Have ◽  
Ron de Graaf ◽  
Matthijs Blankers ◽  
Margriet van Laar
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Population Based ◽  
The Body ◽  
Dose Effect ◽  
Cross Sectional ◽  
Wide Range ◽  
Nationally Representative ◽  
Prospective Association

There is consistent evidence from cross-sectional studies that smoking is positively associated with mental disorders. The research on the prospective association, however, is inconsistent. In the present study, we aimed to further increase the knowledge of this association by addressing several issues in the body of research. Data used were from a nationally representative, population-based cohort study among 18- to 64-year-olds at baseline. Compared with nonsmokers, smokers at baseline were significantly more likely to experience first incidence of any mood, anxiety, or substance use disorder at 3-year follow-up while controlling for a wide range of confounding factors. The association with incident mood and anxiety disorders was particularly high among heavy smokers. The dose-effect analyses on later substance use disorders showed unclear results, warranting further research. Additional analyses showed that results at 6-year follow-up were very similar, except for a weaker relationship between smoking and substance use disorders.

scholarly journals Moral injury and substance use disorders among US combat veterans: results from the 2019–2020 National Health and Resilience in Veterans Study

2021 ◽  
pp. 1-7
Author(s):  
Shira Maguen ◽  
Brandon Nichter ◽  
Sonya B. Norman ◽  
Robert H. Pietrzak
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
National Health ◽  
Combat Veterans ◽  
Population Based ◽  
Moral Injury ◽  
Increased Risk ◽  
Assessment And Treatment ◽  
Multivariable Analyses ◽  
Nationally Representative

Abstract Background Exposure to potentially morally injurious events (PMIEs) is associated with increased risk for substance use disorders (SUDs), although population-based studies remain limited. The goal of this study was to better understand the relationships between PMIE exposure and lifetime and past-year alcohol use disorder (AUD), drug use disorder (DUD), and SUD. Methods Data were analyzed from the 2019–2020 National Health and Resilience in Veterans Study, which surveyed a nationally representative sample of 1321 combat veterans. Multivariable analyses examined associations between three types of PMIE exposure (perpetration, witnessing, and betrayal), and lifetime and past-year AUD, DUD, and SUD, adjusting for sociodemographic variables, combat exposure severity, prior trauma, and lifetime posttraumatic stress disorder and major depressive disorder. Results Perpetration was associated with increased odds of lifetime AUD (OR 1.15; 95% CI 1.01–1.31) and lifetime SUD (OR 1.18; 95% CI 1.03–1.35). Witnessing was associated with greater odds of past-year DUD (OR 1.20; 95% CI 1.04–1.38) and past-year SUD (OR 1.14; 95% CI 1.02–1.28). Betrayal was associated with past-year AUD (OR 1.20; 95% CI 1.03–1.39). A large proportion of the variance in past-year AUD was accounted for by betrayal (38.7%), while witnessing accounted for 25.8% of the variance in past-year DUD. Conclusions Exposure to PMIEs may be a stronger contributor to SUDs among veterans than previously known. These findings highlight the importance of targeted assessment and treatment of moral injury among veterans with SUDs, as well as attending to specific types of morally injurious experiences when conceptualizing and planning care.

scholarly journals Adequate sleep duration among children and adolescents: a review of the Brazil's Report Card

2021 ◽  
Vol 23 ◽  
Author(s):  
Luís Eduardo Argenta Malheiros ◽  
Margarethe Thaisi Garro Knebel ◽  
Marcus Vinicius Veber Lopes ◽  
Gabrielli Thais de Mello ◽  
Valter Cordeiro Barbosa Filho ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Sleep Duration ◽  
Random Sampling ◽  
Population Based ◽  
Original Research ◽  
Age Group ◽  
Cross Sectional ◽  
Wide Range ◽  
Nationally Representative ◽  
Brazilian Children

abstract – This study aimed to summarize existing research examining the prevalence of adequate sleep duration or meeting sleep recommendations among Brazilian children and adolescents. A systematic review was conducted on eight databases. The criteria for inclusion were original research, samples including Brazilian children and adolescents (age 0–18), studies that reported variables regarding sleep duration using both objective or subjective measures, school- or population-based surveys with random sampling, and cross-sectional or cohort studies. Of the 54 articles included, only 27 used data from different studies. Most of the studies were conducted in the southern region (n = 17) with only two studies having a nationally representative sample. Two studies included children below age five, and the age group most investigated was adolescents (>10 years old). A majority of the studies used a self-reported questionnaire and showed variability in the cutoff point applied for adequate sleep duration with the most reported being ≥8 hours. The proportion of adolescents who met recommendations or had adequate sleep duration ranged from 15% to 89%. Among children, the prevalence ranged from 17% to 95%. The least variability was observed among toddlers, ranging from 93% to 95%. No consistent gender differences were observed among the gender-stratified groups of children and adolescents across the studies. It can be observed that, because of the wide range of results and the lack of data with national representativeness, the prevalence of sufficient sleep among young people aged below 18 remains undefined in Brazil.

P050 SUBSTANCE USE OCCURS FREQUENTLY IN PATIENTS WITH CROHN’S DISEASE

2020 ◽  
Vol 26 (Supplement_1) ◽  
pp. S66-S67
Author(s):  
Po-Hung Chen ◽  
Steven Miller ◽  
Steven Brant ◽  
Susan Hutfless
Keyword(s):  
United States ◽  
Substance Use ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Substance Use Disorders ◽  
The United States ◽  
Diagnostic Codes ◽  
Medicaid Eligibility ◽  
Nationally Representative

Abstract Background Crohn’s disease (CD) is an inflammatory disease of the gut with multiple psychosocial comorbidities, including lost wages, stress on loved ones, and psychiatric illnesses, all of which are associated with substance use disorders. While approximately 7.5% of individuals aged 12 or older in the United States have a substance use disorder, we know little about this issue among patients with CD. Using a nationally representative dataset, we examined the burden of alcohol, tobacco, and illicit drug use among patients with CD in the United States. Methods We queried the national Medicaid claims data from 2010 through 2014 using ICD-9-CM codes for CD and use of alcohol, tobacco, opioids, cocaine, amphetamine, and cannabis. We defined CD as having two or more CD diagnostic codes; all included individuals must have at least one continuous year of Medicaid eligibility. The primary outcomes of interest were the total and the substance-specific prevalence of use in patients with CD. Results During our five-year study period, there were 51,091 individuals with CD. Among them, 7.4% had at least one code to suggest substance use, and 1.3% had codes for two or more substance types. Non-users were 65% female, 39-years old at the first CD diagnosis, and had 1.7 years of median follow-up after the said diagnosis. Users were 62% female, 40-years old at the first CD diagnosis, and had 1.8 years of median follow-up after diagnosis. The frequencies of substance use codes by CD patients were tobacco (3.9%), opioids (2.2%), alcohol (1.6%), cannabis (0.4%), cocaine (0.3%) and psychostimulants (0.3%). Conclusion At least 1 in 13 patients with CD in the US Medicaid cohort noted substance use from 2010 through 2014. Our finding was comparable to the reported prevalence of substance use disorders in the general US population.

Caffeine intake, toxicity and dependence and lifetime risk for psychiatric and substance use disorders: an epidemiologic and co-twin control analysis

2006 ◽  
Vol 36 (12) ◽  
pp. 1717-1725 ◽  
Author(s):  
KENNETH S. KENDLER ◽  
JOHN MYERS ◽  
CHARLES O. GARDNER
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Externalizing Disorders ◽  
Population Based ◽  
Caffeine Intake ◽  
Control Analysis ◽  
Entire Sample ◽  
Wide Range ◽  
Broad Array ◽  
Adult Twins

Background. Although caffeine is the most commonly used psychoactive substance and often produces symptoms of toxicity and dependence, little is known, especially in community samples, about the association between caffeine use, toxicity and dependence and risk for common psychiatric and substance use disorders.Method. Assessments of lifetime maximal caffeine use and symptoms of caffeine toxicity and dependence were available on over 3600 adult twins ascertained from the population-based Virginia Twin Registry. Lifetime histories of major depression (MD), generalized anxiety disorder (GAD) and panic disorder, alcohol dependence, adult antisocial behavior and cannabis and cocaine abuse/dependence were obtained at personal interview. Logistic regression analyses in the entire sample and within monozygotic (MZ) twin pairs were conducted in SAS.Results. In the entire sample, measures of maximal caffeine use, heavy caffeine use, and caffeine-related toxicity and dependence were significantly and positively associated with all seven psychiatric and substance use disorders. However, within MZ twin pairs, controlling for genetic and family environmental factors, these associations, while positive, were all non-significant. These results were similar when excluding twins who denied regular caffeine use.Conclusions. Maximal lifetime caffeine intake and caffeine-associated toxicity and dependence are moderately associated with risk for a wide range of psychiatric and substance use disorders. Analyses of these relationships within MZ twin pairs suggest that most of the observed associations are not causal. Rather, familial factors, which are probably in part genetic, predispose to both caffeine intake, toxicity and dependence and the risk for a broad array of internalizing and externalizing disorders.

scholarly journals Vitamin D and Hospital Admission in Older Adults: A Prospective Association

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 616
Author(s):  
Avril Beirne ◽  
Kevin McCarroll ◽  
James Bernard Walsh ◽  
Miriam Casey ◽  
Eamon Laird ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Hospital Admission ◽  
Cross Sectional Study ◽  
Vitamin D Supplementation ◽  
Inverse Association ◽  
Cross Sectional ◽  
Prospective Association ◽  
Randomised Controlled

The health effects of vitamin D are well documented, with increasing evidence of its roles beyond bone. There is, however, little evidence of the effects of vitamin D on hospitalisation among older adults. This study aimed to prospectively determine the relationship of vitamin D status in older adults with hospital admission and emergency department (ED) attendance. Trinity University of Ulster Department of Agriculture (TUDA) is a large cross-sectional study of older adults with a community population from three disease-defined cohorts (cognitive dysfunction, hypertension, and osteoporosis). Participants included in this analysis were recruited between 2008 and 2012. ED and hospital admission data were gathered from the date of TUDA participation until June 2013, with a mean follow up of 3.6 years. Of the 3093 participants, 1577 (50.9%) attended the ED during the period of follow-up. Attendees had lower mean serum 25(OH)D concentrations than non-attendees (59.1 vs. 70.6 nmol/L). Fully adjusted models showed an inverse association between vitamin D and ED attendance (Hazard Ratio (HR) 0.996; 95% Confidence Interval (CI) 0.995–0.998; p < 0.001). A total of 1269 participants (41%) were admitted to hospital during the follow-up. Those admitted had lower mean vitamin D concentrations (58.4 vs. 69.3 nmol/L, p < 0.001). In fully adjusted models, higher vitamin D was inversely associated with hospital admission (HR 0.996; 95% CI 0.994–0.998; p < 0.001) and length of stay (LOS) (β = −0.95, p = 0.006). This study showed independent prospective associations between vitamin D deficiency and increased hospitalisation by older adults. The need for further evaluation of current recommendations in relation to vitamin D supplementation, with consideration beyond bone health, is warranted and should focus on randomised controlled trials.

scholarly journals Sex Difference in the Association between Electronic Cigarette Use and Subsequent Cigarette Smoking among U.S. Adolescents: Findings from the PATH Study Waves 1–4

2021 ◽  
Vol 18 (4) ◽  
pp. 1695
Author(s):  
Zongshuan Duan ◽  
Yu Wang ◽  
Jidong Huang
Keyword(s):  
Mental Health ◽  
Cigarette Smoking ◽  
Tobacco Use ◽  
Mental Health Problems ◽  
Cigarette Use ◽  
Tobacco Products ◽  
Estimation Equations ◽  
Nationally Representative ◽  
Prospective Association

E-cigarettes are the most-used tobacco products among U.S. adolescents. Emerging evidence suggests that adolescents using e-cigarettes are at elevated risk for initiating cigarette smoking. However, whether this risk may differ by sex remains unknown. This study analyzed data from Wave 1 to 4 of the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative longitudinal survey. Generalized estimation equations (GEE) were performed to estimate the associations between baseline e-cigarette use and subsequent cigarette smoking, controlling for sociodemographic characteristics, mental health conditions, and other tobacco use. Effect modifications by sex were examined. Multivariate analyses showed that, among baseline never cigarette smokers, past-30-day e-cigarette use at baseline waves was significantly associated with past-30-day cigarette smoking at follow-up waves (aOR = 3.90, 95% CI: 2.51–6.08). This association was significantly stronger for boys (aOR = 6.17, 95% CI: 2.43–15.68) than for girls (aOR = 1.10, 95% CI: 0.14–8.33). Additionally, using other tobacco products, older age, and having severe externalizing mental health problems at baseline were significantly associated with an increased likelihood of cigarette smoking at follow-up. The prospective association between e-cigarette use and cigarette smoking differs by sex among U.S. adolescents. Sex-specific tobacco control interventions may be warranted to curb the youth tobacco use epidemic.

scholarly journals Ultra-processed food consumption in Barbados: evidence from a nationally representative, cross-sectional study

2021 ◽  
Vol 10 ◽  
Author(s):  
Rachel M. Harris ◽  
Angela M. C. Rose ◽  
Suzanne Soares-Wynter ◽  
Nigel Unwin
Keyword(s):  
Communicable Disease ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Targeted Interventions ◽  
Sweetened Beverages ◽  
Group 4 ◽  
The Mean ◽  
Nationally Representative

Abstract Our objective was to describe, for the first time in an English-speaking Caribbean country, the contribution of ultra-processed foods (UPFs) to nutrients linked to non-communicable disease. Using a cross-sectional study design, dietary data were collected from two non-consecutive 24-h dietary recalls. Recorded food items were then classified according to their degree of processing by the NOVA system. The present study took place in Barbados (2012–13). A representative population-based sample of 364 adult Barbadians (161 males and 203 females) aged 25–64 years participated in the study. UPFs represented 40⋅5 % (838 kcal/d; 95 % CI 791, 885) of mean energy intake. Sugar-sweetened beverages made the largest contribution to energy within the UPF category. Younger persons (25–44 years) consumed a significantly higher proportion of calories from UPF (NOVA group 4) compared with older persons (45–64 years). The mean energy shares of UPF ranged from 22⋅0 to 58⋅9 % for those in the lowest tertile to highest tertile. Within each tertile, the energy contribution was significantly higher in the younger age group (25–44 years) compared with the older (45–64 years). One-quarter of persons consume ≥50 % of their daily calories from UPF, this being significantly higher in younger persons. The ultra-processed diet fraction contained about six times the mean of free sugars and about 0⋅8 times the dietary fibre of the non-ultra-processed fraction (NOVA groups 1–3). Targeted interventions to decrease the consumption of UPF especially in younger persons is thus of high priority to improve the diet quality of Barbadians.

scholarly journals Effects of lowered serotonin transmission on cocaine-induced striatal dopamine response: PET [11C]raclopride study in humans

2011 ◽  
Vol 199 (5) ◽  
pp. 391-397 ◽  
Author(s):  
Sylvia M. L. Cox ◽  
Chawki Benkelfat ◽  
Alain Dagher ◽  
J. Scott Delaney ◽  
France Durand ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Striatal Dopamine ◽  
Emission Tomography ◽  
Acute Tryptophan Depletion ◽  
Tryptophan Depletion ◽  
Comorbid Conditions ◽  
Drug Craving ◽  
Positron Emission ◽  
Wide Range

BackgroundLow serotonin transmission is thought to increase susceptibility to a wide range of substance use disorders and impulsive traits.AimsTo investigate the effects of lowered serotonin on cocaine-induced (1.0 mg/kg cocaine, self-administered intranasally) dopamine responses and drug craving.MethodIn non-dependent cocaine users, serotonin transmission was reduced using the acute tryptophan depletion method. Striatal dopamine responses were measured using positron emission tomography with [11C]raclopride.ResultsAcute tryptophan depletion increased drug craving and striatal dopamine responses to cocaine. These acute tryptophan depletion-induced increases did not occur in the absence of cocaine.ConclusionsThe results suggest that low serotonin transmission can increase dopaminergic and appetitive responses to cocaine. These findings might identify a mechanism by which individuals with low serotonin are at elevated risk for both substance use disorders and comorbid conditions.

Standard EMDR Protocol for Alcohol and Substance Dependence Comorbid With Posttraumatic Stress Disorder: Four Cases With 12-Month Follow-Up

2016 ◽  
Vol 10 (1) ◽  
pp. 33-46 ◽  
Author(s):  
Claire Kullack ◽  
Jonathan Laugharne
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Substance Use ◽  
Alcohol Dependence ◽  
Posttraumatic Stress ◽  
Substance Use Disorders ◽  
Substance Dependence ◽  
Stress Disorder ◽  
Case Series ◽  
Post Traumatic Stress

This report begins with a summary of the literature regarding the theoretical models behind the comorbid relationship between posttraumatic stress disorder and substance use disorders and the various modified addiction protocols formulated to assist in treating these disorders. This case series outlines the effect that the standard eye movement desensitization and reprocessing (EMDR) protocol had on alcohol and substance dependence for 4 patients who attended our Post Traumatic Stress Clinic in Fremantle, Western Australia, primarily for treatment for posttraumatic stress disorder. Patients were assessed for substance use disorders using the Mini International Neuropsychiatric Interview Plus prior to, immediately after, and 12 months after completing EMDR therapy. Results indicate that the standard EMDR protocol was successful in reducing alcohol and substance use. Prior to treatment, 3 patients met criteria for alcohol dependence and 1 met criteria for substance dependence. At 12-month follow-up, 3 out of 4 clients did not meet the diagnostic criteria for current alcohol dependence or current substance dependence. The implications of these findings are discussed with reference to theories of comorbid posttraumatic stress disorder and substance use disorder and the modified EMDR protocols developed for patients with substance dependence.

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