Advantages wth Using the Levonorgestrel-Releasing Intrauterine System in Females with Hemostatic Disorders.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 3303-3303
Author(s):  
Andrea S. Lukes ◽  
Gowthami Arepally
Keyword(s):  
Quality Of Life ◽  
Large Scale ◽  
Case Series ◽  
Factor V Leiden ◽  
Menstrual Bleeding ◽  
Effective Control ◽  
Bleeding Complications ◽  
Life Questionnaire ◽  
Hemostatic Disorders

Abstract BACKGROUND: The levonorgestrel-releasing intrauterine system (LNG-IUS) is a small device placed within the uterus that is used for both contraception and treatment of menorraghia. This system releases 20 micrograms of levonorgestrel every 24 hours over 5 years. We hypothesized that females with inherited or acquired bleeding disorders would have decreased menstrual bleeding with the LNG-IUS and improved quality of life. METHODS: A small, retrospective case series of females with hemostatic disorders who used the LNG-IUS within a 2 year period and who were seen at a tertiary medical center. RESULTS: Seven females were treated with the LNG-IUS for menorrhagia and contraception. We did not reverse anticoagulation for placement of the device and there were no bleeding complications associated with the LNG-IUS insertion. The average age was 36.7 years (range 28 – 48 years). Four females had von Willebrand’s disease (VWD). Four females were on antithrombotic therapy, 2 warfarin and 2 aspirin. One female with VWD was heterozygous for factor V Leiden and was on warfarin for treatment of deep venous thrombosis. Six females had menorrhagia and one had bleeding most of the time. The average days of menstrual bleeding prior to LNG-IUS was 8.3 days which improved to 4.5 days after placement of the LNG-IUS. Three of 7 females discontinued use of the LNG-IUS, yet one had the LNG-IUS removed because she no longer required contraception. This female became pregnant and after an uncomplicated normal spontaneous vaginal delivery elected to use the LNG-IUS again for contraception and the benefit of decreased menstrual bleeding. The other 2 females (2/7, 29%) discontinued use of the LNG-IUS because there was worsening of heavy menses or ‘failed’ therapy - one with VWD and one on anticoagulation. The female on anticoagulation in this case also had significant uterine fibroids. A ten item quality of life questionnaire developed by Kouides was administered, and showed overall improvement in quality of life. CONCLUSION: The levonorgestrel-releasing intrauterine system is an effective method of contraception and an effective treatment for heavy menses. For females with hemostatic disorders, this device has unique advantages: it is technically easy to use in females at increased bleeding risk, offers effective control of menorrhagia, and may likely improve overall quality of life. Additional prospective large scale studies are required to validate these findings.

Translation and Validation of the Thai Version of the Wisconsin Quality of Life Questionnaire (TH WISQoL) for Kidney Stone Patients

2020 ◽  
Vol 103 (11) ◽  
pp. 1194-1199
Keyword(s):  
Quality Of Life ◽  
Internal Consistency ◽  
Kidney Stone ◽  
Convergent Validity ◽  
Large Scale ◽  
Short Form ◽  
Outcome Measurement ◽  
Life Questionnaire ◽  
Sf 36

Objective: To develop and validate a Thai version of the Wisconsin Quality of Life (TH WISQoL) Questionnaire. Materials and Methods: The authors developed the TH WISQoL Questionnaire based on a standard multi-step process. Subsequently, the authors recruited patients with kidney stone and requested them to complete the TH WISQoL and a validated Thai version of the 36-Item Short Form Survey (TH SF-36). The authors calculated the internal consistency and interdomain correlation of TH WISQoL and compared the convergent validity between the two instruments. Results: Thirty kidney stone patients completed the TH WISQoL and the TH SF-36. The TH WISQoL showed acceptable internal consistency for all domains (Cronbach’s alpha 0.768 to 0.909). Interdomain correlation was high for most domains (r=0.698 to 0.779), except for the correlation between Vitality and Disease domains, which showed a moderate correlation (r=0.575). For convergent validity, TH WISQoL demonstrated a good overall correlation to TH SF-36, (r=0.796, p<0.05). Conclusion: The TH WISQoL is valid and reliable for evaluating the quality of life of Thai patients with kidney stone. A further large-scale multi-center study is warranted to confirm its applicability in Thailand. Keywords: Quality of life, Kidney stone, Validation, Outcome measurement

scholarly journals Visual Outcomes, Quality of Vision, and Quality of Life of Diffractive Multifocal Intraocular Lens Implantation after Myopic Laser In Situ Keratomileusis: A Prospective, Observational Case Series

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
John S. M. Chang ◽  
Jack C. M. Ng ◽  
Vincent K. C. Chan ◽  
Antony K. P. Law
Keyword(s):  
Quality Of Life ◽  
Contrast Sensitivity ◽  
Intraocular Lens ◽  
Case Series ◽  
Visual Performance ◽  
Laser In Situ Keratomileusis ◽  
Life Questionnaire ◽  
Multifocal Intraocular Lens

Purpose. To report visual performance and quality of life after implantation of a bifocal diffractive multifocal intraocular lens (MIOL) in postmyopic laser in situ keratomileusis (LASIK) patients.Methods. Prospective, observational case series. Patients with prior myopic LASIK who had implantation of Tecnis ZMA00/ZMB00 MIOL (Abbott Medical Optics) at Hong Kong Sanatorium and Hospital were included. Postoperative examinations included monocular and binocular distance, intermediate and near visual acuity (VA), and contrast sensitivity; visual symptoms (0–5); satisfaction (1–5); spectacle independence rate; and quality of life.Results. Twenty-three patients (27 eyes) were included. No intraoperative complications developed. Mean monocular uncorrected VA at distance, intermediate, and near were0.13±0.15(standard deviation),0.22±0.15, and0.16±0.15, respectively. Corresponding mean values for binocular uncorrected VA were0.00±0.10,0.08±0.13, and0.13±0.10, respectively. No eyes lost >1 line of corrected distance VA. Contrast sensitivity at different spatial frequencies between operated and unoperated eyes did not differ significantly (allP>0.05). Mean score for halos, night glare, starbursts, and satisfaction were1.46±1.62,1.85±1.69,0.78±1.31, and3.50±1.02, respectively. Eighteen patients (78%) reported complete spectacle independence. Mean composite score of the quality-of-life questionnaire was90.31±8.50out of 100.Conclusions. Implantation of the MIOL after myopic LASIK was safe and achieved good visual performance.

scholarly journals Evaluation of quality of life and radiological parameters after hallux valgus correction

2019 ◽  
Vol 13 (1) ◽  
pp. 3-9
Author(s):  
Vinícius Trindade Cardoso ◽  
Henrique Mansur ◽  
Isnar Moreira Castro Junior
Keyword(s):  
Quality Of Life ◽  
Hallux Valgus ◽  
Case Series ◽  
Life Questionnaire ◽  
Level Of Evidence ◽  
Significance Level ◽  
Radiological Parameters ◽  
Sf 36 ◽  
Student’S T

Objective: To evaluate the quality of life of patients undergoing hallux valgus correction and maintenance of  radiographic parameters over time. Methods: The study included 38 patients who underwent hallux valgus correction surgery using different osteotomy techniques (Scarf, Chevron, Arciform, Proximal Chevron and Chevron-Akin) between January 2010 and December 2012. The patients were evaluated radiographically at 3 different periods (preoperatively and 1 year and 5 years postoperatively) and completed the SF-36 quality-of life questionnaire. Statistical analysis was performed using Student’s t-test and the nonparametric Wilcoxon and Friedman tests at a maximum significance level of 5%. Results: Among the main results obtained for the SF-36 questionnaire, the domain patients felt better about emotional aspects, physical limitations and social aspects, with a final mean of 74.9. The metatarsophalangeal and intermetatarsal angles and medial eminence exhibited significant reductions in the postoperative period (p<0.05), and only 1 patient presented with the loss of joint congruence. Conclusion: Different surgical osteotomy techniques used to correct moderate and severe hallux valgus provide improvements in the radiological parameters and quality of life of patients. Level of Evidence IV; Therapeutic Studies; Case Series.

Self-Reported Allergic Rhinitis Prevalence and Related Factors in Civil Aviation Aircrew of China

2021 ◽  
Vol 92 (1) ◽  
pp. 25-31
Author(s):  
Yin Bai ◽  
Mosheng Hu ◽  
Fengjie Ma ◽  
Ke Liu ◽  
Haijun Xu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Allergic Rhinitis ◽  
Large Scale ◽  
Civil Aviation ◽  
Life Questionnaire ◽  
Related Factors ◽  
Flight Duration ◽  
Nasal Symptoms

INTRODUCTION: Allergic rhinitis (AR) is a global health problem with gradually increasing prevalence. No large-scale, systematic, and comprehensive study on AR among civil aviation aircrew of China has been reported. We aimed to demonstrate the prevalence of and risk factors for self-reported AR among Chinese civil aviation aircrew.METHODS: This study randomly surveyed 4059 civil aviation aircrew members from 12 cities in mainland China. A structured questionnaire was tailored, designed, and electronically delivered to all participants. Based on self-reported results, prevalence of and risk factors for AR were calculated/analyzed.RESULTS: The prevalence of self-reported AR was 23.38%. Among aircrew members, 10.37% presented with ear barotraumas, whereas 9.95% reported symptom aggravation during flight. Of aircrew members, 10.32% had symptoms related to flight duration, whereas 4.43% of symptoms related to flight altitude. Significant differences between rhinorrhea and sneezing, as well as between nasal itching and sneezing, were observed in the Total Nasal Symptoms Scores (TNSS). The Rhino-conjunctivitis Quality of Life Questionnaire (RQLQ) showed significant correlation between each section. TNSS was significantly related to RQLQ. Both TNSS and RQLQ significantly correlated with flight time.CONCLUSIONS: The prevalence of self-reported AR among civil aviation aircrew is higher than the general population in China. The severity of nasal symptoms and complications are significantly associated with quality of life and flying duties.Bai Y, Hu M, Ma F, Liu K, Xu H, Wu X, Wang H. Self-reported allergic rhinitis prevalence and related factors in civil aviation aircrew of China. Aerosp Med Hum Perform. 2021; 92(1):2531.

scholarly journals Assessment of quality of life in a retrospective study of total oral rehabilitation of the upper jaw with transzygomatic fixation - Case series

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Luis Pinheiro
Keyword(s):  
Quality Of Life ◽  
Retrospective Study ◽  
Case Series ◽  
Life Questionnaire ◽  
Oral Rehabilitation ◽  
Time Points ◽  
Atrophic Maxilla ◽  
Zygomatic Implants ◽  
The Impact

Purpose: Zygomatic implants are becoming more common in oral rehabilitation of atrophic maxilla. Successful surgery and rehabilitation are mandatory for the achievement of a well-defined criteria of Quality of Life. However, there is a paucity of studies reporting on the Health-Related Quality of Life in patients undergoing oral rehabilitation. This article aims to developing a specific questionnaire for this particular surgical and rehabilitation procedure that could be an objective quality outcome measure of Quality of Life. This should improve our understanding of the impact of zygomatic implant placement on Quality of Life. Materials and Methods: The study was performed involving the Eastman Dental Institute - University College of London, the Faculty of Sciences - University of Lisbon, and two private practices in Portugal, C.E.R.O-Lisboa and Clitrofa. This was a retrospective study, evolving 30 patients undergoing TransZygomatic Surgery. A modification of the University of Washington – Quality of Life Questionnaire was designed for this work. The evaluation was made in three-time points: TP1 – Before surgery, TP2 - After surgery and TP3 - After final rehabilitation. Results: The means of the increased Quality of Life between the different time-points were found to be statistically significance at the level of 0.05, with a confidence interval of 95%. Conclusion: With this Questionnaire, important data was collected which should allow treatment developments to optimise patients Quality of Life.

Sacral electroacupuncture as a treatment for urge urinary incontinence: a prospective case series

2020 ◽  
pp. 096452842096884
Author(s):  
Shan Chen ◽  
Siyou Wang ◽  
Lihua Xuan ◽  
Fu Xu ◽  
Hanti Lu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Urinary Incontinence ◽  
Case Series ◽  
Urge Urinary Incontinence ◽  
Life Questionnaire ◽  
Improvement Rate ◽  
Significant Difference ◽  
Before And After ◽  
The Impact

Objective: To examine the impact of electroacupuncture (EA) at the ‘four sacral points’ on urge urinary incontinence (UUI). Methods: Twenty-five patients diagnosed with UUI or urgency-predominant mixed urinary incontinence (MUI) were treated by EA at the ‘four sacral points’. EA was performed in the sacrococcygeal region using disposable sterile 0.40-mm-diameter acupuncture needles that were either 100 or 125 mm in length. Treatments were delivered once every other day. Before and after treatment, a questionnaire measuring symptom severity and quality of life associated with UUI was administered. Results: The median total score (interquartile range) from the severity of symptoms and the quality of life questionnaire (Q-score) of the participants was significantly reduced from 12 (7.5, 15) before treatment to 3 (0, 6) after 6 (6, 12) EA treatments. The Q-score of urgency-predominant MUI and UUI was 8 (5, 14.5) and 12.5 (11, 15), respectively, before treatment; after treatment these were reduced to 2 (0, 7.5) and 4.5 (2, 6), respectively. There was no statistically significant difference in the Q-score between urgency-predominant MUI and UUI before and after treatment. Upon treatment completion, seven patients (28%) were ‘cured’ (improvement rate 100%). Treatments were considered ‘markedly effective’ (improvement rate 75% to <100%) in four patients (16%), ‘effective’ (improvement rate 50% to <75%) in eight patients (32%), ‘minimally effective’ (improvement rate 25% to <50%) in three patients (12%), and ‘ineffective’ (improvement rate <25%) in three patients (12%). The overall success rate (comprising ‘cured’, ‘markedly effective’ and ‘effective’ categories) was 76%, and no adverse effects associated with acupuncture treatment were reported. Conclusion: EA at the ‘four sacral points’ was associated with statistically significant improvements in UUI.

scholarly journals Acupuncture for Quality of Life of Patients with Defecation Dysfunction after Sphincter Preserving Surgery for Rectal Cancer: A Systematic Review

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Guixing Xu ◽  
Hanzhou Lei ◽  
Yuanfang Zhou ◽  
Liuyang Huang ◽  
Hao Tian ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Rectal Cancer ◽  
Large Scale ◽  
Risk Of Bias ◽  
Mean Difference ◽  
Original Research ◽  
Life Questionnaire ◽  
Medium Risk

Purpose. To evaluate the effectiveness and safety of acupuncture for quality of life of patients with defecation dysfunction (DD) after sphincter preserving surgery for rectal cancer. Methods. We searched nine online databases from inception to July 1, 2021, and did not restrict the type of language. Then, studies were independently selected by two research team members with screening criteria and risk bias assessment, and the data were extracted. The primary outcome was Quality of Life Questionnaire-Core 29 (QLQ-CR29). The data were then synthesized using the RevMan V.5.2 by random-effects model. Also, we used the standardized mean differences with 95% credible interval (CI) to describe the outcome of the analysis. Results. A total of 6 randomized controlled trials (RCTs) (with 439 patients) were included in the systematic review, and data from 2 RCTs (with 200 patients) were used in the meta-analysis. Five studies (83%) were judged to have a medium risk of bias, and one was at high risk of bias. For synthesis, data from two medium-risk studies found that acupuncture or electropuncture may improve the QLQ-CR29 with urination (mean difference, −0.39 points; 95%CI, −0.46 to −0.32; I2 = 34%), abdominal pain (mean difference, −0.71 points; 95%CI, −0.89 to −0.54; I2 = 9%), stool (mean difference, −0.49 points; 95%CI, −0.77 to −0.20; I2 = 57%), defecation (mean difference, −0.59 points; 95% CI, −0.85 to −0.33; I2 = 51%), sexual function (mean difference, 0.93 points; 95% CI, 0.48 to 1.38; I2 = 90%), and self-feelings (mean difference, 1.04 points; 95% CI, 0.36 to 1.73; I2 = 94%). Conclusion. Findings in this study indicate that acupuncture or electropuncture may be effective and safe for DD, but the quality of included studies was very low. So, more large-scale, multicenter, long-term, and high-quality original research is still expected in the future.

Alexithyme Patientenmerkmale und Lebensqualität – Eine Querschnittsstudie an 79 ambulanten Patienten mit Angststörungen

2013 ◽  
Vol 61 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Katrin Leenen ◽  
Michael Rufer ◽  
Hanspeter Moergeli ◽  
Hans-Jörgen Grabe ◽  
Josef Jenewein ◽  
...  
Keyword(s):  
Quality Of Life ◽  
World Health ◽  
Life Questionnaire ◽  
World Health Organization Quality ◽  
Fand Sich ◽  
Quality Of Life Questionnaire ◽  
Organization Quality ◽  
Health Organization ◽  
Tas 20

Aus Untersuchungen in der Normalbevölkerung ist bekannt, dass Menschen mit erhöhten Alexithymiewerten eine verminderte Lebensqualität (LQ) aufweisen. Für Patienten mit psychischen Störungen wurde dieser Zusammenhang jedoch kaum untersucht. Ziel dieser Studie war es, den möglichen Zusammenhang zwischen alexithymen Patientenmerkmalen und der LQ bei Patienten mit Angststörungen zu überprüfen. Bei 79 ambulanten Patienten mit Angststörungen wurden alexithyme Charakteristika mit der Toronto Alexithymia Scale (TAS-20), die LQ mit der Kurzversion des World Health Organization Quality of Life Questionnaire 100 (WHOQOL-BREF) erfasst. Darüber hinaus fand eine Erhebung der psychischen Symptombelastung (SCL-90-R) und depressiven Symptomatik (MADRS) statt. Mittels hierarchischer Regressionsanalysen wurde der Zusammenhang zwischen der alexithymen Charakteristika und den unterschiedlichen LQ-Domänen berechnet. Die Patienten zeigten eine im Vergleich zur Normalbevölkerung deutlich verminderte LQ. Als Hauptergebnis fand sich, auch nach Kontrolle von Depression, Ängstlichkeit und Geschlecht, ein signifikanter Zusammenhang zwischen den beiden TAS-20 Subskalen Schwierigkeiten, Gefühle zu identifizieren und zu beschreiben und vor allem der psychischen LQ. Unsere Ergebnisse sprechen dafür, bei der Diagnostik und Therapieplanung von Patienten mit Angststörungen alexithyme Merkmale einzubeziehen. Im Falle von ausgeprägten alexithymen Merkmalen sollten psychotherapeutische Interventionen zur Verbesserung der Schwierigkeiten Gefühle wahrzunehmen und zu kommunizieren in Betracht gezogen werden.

Cathartic Effect of Suicide Attempts Not Limited to Depression

Crisis ◽  
2003 ◽  
Vol 24 (2) ◽  
pp. 73-78 ◽  
Author(s):  
Yves Sarfati ◽  
Blandine Bouchaud ◽  
Marie-Christine Hardy-Baylé
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Personality Traits ◽  
Rating Scales ◽  
Suicide Attempts ◽  
World Health ◽  
Life Questionnaire ◽  
Short Term

Summary: The cathartic effect of suicide is traditionally defined as the existence of a rapid, significant, and spontaneous decrease in the depressive symptoms of suicide attempters after the act. This study was designed to investigate short-term variations, following a suicide attempt by self-poisoning, of a number of other variables identified as suicidal risk factors: hopelessness, impulsivity, personality traits, and quality of life. Patients hospitalized less than 24 hours after a deliberate (moderate) overdose were presented with the Montgomery-Asberg Depression and Impulsivity Rating Scales, Hopelessness scale, MMPI and World Health Organization's Quality of Life questionnaire (abbreviated versions). They were also asked to complete the same scales and questionnaires 8 days after discharge. The study involved 39 patients, the average interval between initial and follow-up assessment being 13.5 days. All the scores improved significantly, with the exception of quality of life and three out of the eight personality traits. This finding emphasizes the fact that improvement is not limited to depressive symptoms and enables us to identify the relative importance of each studied variable as a risk factor for attempted suicide. The limitations of the study are discussed as well as in particular the nongeneralizability of the sample and setting.

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