scholarly journals The Effect of Surgery on the Concentration of Circulating Megakaryocytes and Platelets

Blood ◽  
1968 ◽  
Vol 32 (3) ◽  
pp. 393-401 ◽  
Author(s):  
ALEXANDER BRESLOW ◽  
RICHARD M. KAUFMAN ◽  
ALAN R. LAWSKY
Keyword(s):  
Maximal Level ◽  
Men And Women ◽  
The Third ◽  
Antecubital Vein ◽  
Platelet Concentration ◽  
The Mean ◽  
Normal Men ◽  
Mean Concentration

Abstract The mean concentration of megakaryocytes in antecubital vein blood of 43 normal men and women was 3.4/ml. (range 0-13). No circulating megakaryocytes were found in 6 patients with thrombocytopenia due to marrow failure. Following surgery the average maximal megakaryocyte level increased to 50/ml. (range 15-190) from a preoperative mean of 8/ml. The maximal level was reached on about the third postoperative day with the platelet concentration reaching maximal levels 3 to 6 days later.

PROTEIN BINDING OF CORTISOL IN HEALTH AND IN PREGNANCY

1961 ◽  
Vol 23 (1) ◽  
pp. 25-35 ◽  
Author(s):  
MOLLIE BOOTH ◽  
P. F. DIXON ◽  
C. H. GRAY ◽  
J. M. GREENAWAY ◽  
N. J. HOLNESS
Keyword(s):  
Pregnant Women ◽  
Binding Sites ◽  
Plasma Cortisol ◽  
Equilibrium Constants ◽  
Qualitative Difference ◽  
Mean Values ◽  
The Mean ◽  
Normal Men ◽  
Mean Concentration ◽  
In Pregnancy

SUMMARY The binding of plasma cortisol to transcortin at 37° c was studied in normal men and in non-pregnant and pregnant women. The mean concentrations of transcortin were 8, 11·5 and 14 × 10−7 moles/l. and the percentages of the binding sites occupied by cortisol were 45, 24 and 40%, respectively. The mean values of the equilibrium constants were 2·9, 1·8 and 4·6 × 107 l./mole, suggesting that there might be a qualitative difference in transcortin from the three groups. The mean concentration of diffusible cortisol was 1·12 μg./100 ml. in men and 0·65 μg./100 ml. in non-pregnant and pregnant women. The significance of these findings is discussed.

CORTISOL AND CORTISONE IN SALIVA OF PREGNANCY

1963 ◽  
Vol 26 (2) ◽  
pp. 189-195 ◽  
Author(s):  
M. S. GREAVES ◽  
H. F. WEST
Keyword(s):  
Rheumatoid Arthritis ◽  
Salivary Gland ◽  
Pregnant Women ◽  
Connective Tissues ◽  
Third Trimester ◽  
The Third ◽  
Reasonable Explanation ◽  
The Mean ◽  
Mixed Saliva ◽  
Mean Concentration

SUMMARY The concentration of cortisol and cortisone in mixed saliva has been measured in normal non-pregnant women, normal pregnant women in the third trimester of pregnancy and pregnant ones with mild toxaemia in the third trimester. The ratio of cortisol to cortisone was 1:4 for the non-pregnant and 1:5 for the pregnant women. The mean concentration of cortisol for the pregnant subjects was twice that of the non-pregnant and the mean concentration of cortisone three times that of the non-pregnant women. Filtration studies showed no significant binding of cortisol or cortisone in the saliva. It is concluded that the raised concentration of cortisol and cortisone in saliva indicates a raised concentration in the cells of the salivary gland. If this rise is common to the connective tissues generally it provides a reasonable explanation for the remission of rheumatoid arthritis experienced by some patients in the latter months of pregnancy.

Leukotriene B4 and late asthmatic reactions induced by toluene diisocyanate

1990 ◽  
Vol 68 (4) ◽  
pp. 1576-1580 ◽  
Author(s):  
E. Zocca ◽  
L. M. Fabbri ◽  
P. Boschetto ◽  
M. Plebani ◽  
M. Masiero ◽  
...  
Keyword(s):  
High Performance ◽  
Leukotriene B4 ◽  
Toluene Diisocyanate ◽  
Reverse Phase ◽  
The Third ◽  
Specific Radioimmunoassay ◽  
Asthmatic Reaction ◽  
The Mean ◽  
Late Asthmatic Reaction ◽  
Mean Concentration

We investigated whether leukotriene B4 (LTB4) is released from the lungs of sensitized subjects during asthmatic reactions induced by toluene diisocyanate (TDI). We examined three groups of TDI-sensitized subjects, one after no exposure to TDI, the second 8 h after an exposure to TDI that caused an early asthmatic reaction, and the third 8 h after an exposure to TDI that caused a late asthmatic reaction. We analyzed bronchoalveolar lavage (BAL) fluid by reverse-phase high-performance liquid chromatography and by specific radioimmunoassay. The mean concentration of LTB4 was higher [0.31 +/- 0.09 (SE) ng/ml, range 0.15-0.51] in BAL fluid of sensitized subjects who developed a late asthmatic reaction than in BAL fluid of subjects who developed an early asthmatic reaction (0.05 +/- 0.04 ng/ml, range 0-0.224), and no LTB4 was detectable in the control subjects. We also performed BAL 8 h after TDI exposure on four TDI-sensitized late-dual reactors who were on steroid treatment. In this group of subjects no LTB4 was detectable. These results suggest that LTB4 may be involved in late asthmatic reactions induced by TDI.

URINARY GONADOTROPHINS FOLLOWING CASTRATION OF MEN

1973 ◽  
Vol 74 (1) ◽  
pp. 79-87
Author(s):  
Peter Christiansen
Keyword(s):  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Maximal Level ◽  
The Mean ◽  
Normal Men ◽  
Stimulating Hormone

ABSTRACT The excretion of total hypophyseal gonadotrophins (HG), follicle stimulating hormone (FSH) and luteinizing hormone (LH) was studied in 13 castrated men aged 23 to 56 years, mean 38.8 years. All the men were castrated for legal reasons. The time from castration to the investigation varied from 4 weeks to 24 years. Four of the subjects were studied from the time before surgery until 4 weeks after castration. The mean excretion of HG, FSH and LH was statistically significantly higher than that of normal men of the same age i. e. by 8, 9 and 3 times higher respectively. The FSH/LH ratio was in the mean 2.8. Following orchiectomy FSH rose more rapidly and to a higher level than LH. The maximal level of FSH was reached within 1–2 weeks after castration in contrast to LH which did not consistently reach the maximal level within 4 weeks. This difference in FSH and LH levels after castration supports the concept that FSH and LH are regulated independently in man.

scholarly journals Effect of Inhibin-B hormone and its relationship with a number of sex hormones in men with Azoospermia

2019 ◽  
Vol 24 (3) ◽  
pp. 11
Author(s):  
Alaa Abdullah ali ◽  
Hadeel Abdulhadi Omear1 ◽  
Mazin Anwar alobaydi2
Keyword(s):  
Positive Relationship ◽  
Sperm Count ◽  
Feedback Mechanism ◽  
Inhibin B ◽  
Negative Feedback Mechanism ◽  
The Mean ◽  
Follicular Stimulation ◽  
Normal Men ◽  
The Relationship ◽  
Mean Concentration

Inhibin-B is produced by sertoli cells and acts as a negative feedback mechanism of follicular stimulation hormone (FSH). In order to evaluate the effect of Inhibin-B in men with Azoospermia, the study measured the concentrations of the following hormones: Inhibin-B, FSH, Luteinizing Hormone Prolactin (PRL), (LH) and Testosterone (Testo). Serum for 30 normal men semen and 50 men with Azoespermia (zero sperm count in sperm). The mean concentration of the hormone Inhibin-B in patients with Azoospermia was (135.7 ±87.6) pg/ml, while in normal men (175.6 ±47.9) Pg / ml with a significant value of the group of healthy patients at a significant level (p≤0.01). The mean serum FSH concentration in patients was (13.7 ± 12.27) lU / L whereas in normal men (4.1 ± 2.84) lU / L, the relationship was significant between patients and healthy at a significant level (P≤0.01) the correlation with the Inhibin-B  hormone is reversible relationship. The mean concentration of LH in patients was (12.8±11.87) IU/L and in the healthy (7.9±5.57) IU/L and the relationship between them was significant  (P≤0.05) and the correlation with the Inhibin-B hormone is positive relationship. The mean concentration of the  Testosterone In the patients was  (2.37 ± 1.22) IU / L and in the healthy (5.1 ± 1.96) IU/ L, the relationship was of significant value at P≤0.01 and the correlation with the Inhibin-B hormone is positive relationship, and there is a difference in the mean concentration of PRL between the patients and the healthy where it reaches (8.88 ±5.16) IU / L in patients and (8.03 ± 4.2) IU / L in the healthy. where the relationship was non-significant value between both patients and healthy and the correlation with the Inhibin-B hormone is positive relationship .   http://dx.doi.org/10.25130/tjps.24.2019.042

EFFECTS OF EPINEPHRINE ON THE PRODUCTION AND METABOLIC CLEARANCE OF CORTISOL IN NORMAL MEN AND WOMEN AND IN WOMEN WITH IDIOPATHIC HIRSUTISM

1966 ◽  
Vol 53 (4) ◽  
pp. 561-570 ◽  
Author(s):  
E. J. Segre ◽  
E. H. Friedrich ◽  
O. I. Dodek ◽  
C. W. Lloyd ◽  
J. Lobotsky ◽  
...  
Keyword(s):  
Constant Infusion ◽  
Metabolic Clearance ◽  
Metabolic Clearance Rate ◽  
Men And Women ◽  
Plasma Cortisol Concentration ◽  
Baseline Cortisol ◽  
Idiopathic Hirsutism ◽  
The Mean ◽  
Normal Women ◽  
Normal Men

ABSTRACT The influence of epinephrine on the metabolic clearance rate (MCR) and production rate (PR) of cortisol was determined in normal men and women and in women with idiopathic hirsutism. MCR was measured using a constant infusion of 3H-cortisol and PR calculated as the product of MCR and plasma cortisol concentration according to the model of Tait. After control observations 0.5 μg/kg epinephrine was injected intravenously in one minute followed by a constant infusion at a rate of 0.5 mg/h. The mean cortisol MCR was 10.3 litres/h in males and 7.9 litres/h in females. In neither sex was it altered by epinephrine. The mean baseline cortisol PR in males was 568 μg/h; it increased to 940 μg/h with epinephrine (P < .025 > .01). In hirsute females the mean baseline cortisol PR was 697 μg/h with an increase to 1067 μg/h with epinephrine. In normal females, the increase in cortisol PR was less (515 μg/h to 638 μg/h). Adrenal responsiveness to epinephrine, as measured by the production of cortisol, appears greater in hirsute than in normal women. Possible relationships between this difference and the development of hirsutism are discussed.

scholarly journals Distribution of Salivary Testosterone in Men and Women in a British General Population-Based Sample: The Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)

2017 ◽  
Vol 1 (1) ◽  
pp. 14-25 ◽  
Author(s):  
Brian G. Keevil ◽  
Soazig Clifton ◽  
Clare Tanton ◽  
Wendy Macdowall ◽  
Andrew J. Copas ◽  
...  
Keyword(s):  
General Population ◽  
National Survey ◽  
Sexual Attitudes ◽  
Geometric Mean ◽  
Sample Survey ◽  
Men And Women ◽  
Salivary Testosterone ◽  
The Third ◽  
Population Distributions ◽  
The Mean

Abstract Introduction: Measurement of salivary testosterone (Sal-T) to assess androgen status offers important potential advantages in epidemiological research. The utility of the method depends on the interpretation of the results against robustly determined population distributions, which are currently lacking. Aim: To determine age-specific Sal-T population distributions for men and women. Methods: Morning saliva samples were obtained from participants in the third National Survey of Sexual Attitudes and Lifestyles, a probability sample survey of the British general population. Sal-T was measured using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Linear and quantile regression analyses were used to determine the age-specific 2.5th and 97.5th percentiles for the general population (1675 men and 2453 women) and the population with health exclusions (1145 men and 1276 women). Results: In the general population, the mean Sal-T level in men decreased from 322.6 pmol/L at 18 years of age to 153.9 pmol/L at 69 years of age. In women, the decrease in the geometric mean Sal-T level was from 39.8 pmol/L at 18 years of age to 19.5 pmol/L at 74 years of age. The annual decrease varied with age, with an average of 1.0% to 1.4% in men and 1.3% to 1.5% in women. For women, the 2.5th percentile fell below the detection limit (&lt;6.5 pmol/L) from age 52 years onward. The mean Sal-T level was approximately 6 times greater in men than in women, and this remained constant over the age range. The Sal-T level was lowest for men and highest for women in the summer. The results were similar for the general population with exclusions. Conclusions: To our knowledge, this is the first study to describe the sex- and age-specific distributions for Sal-T in a large representative population using a specific and sensitive LC-MS/MS technique. The present data can inform future population research by facilitating the interpretation of Sal-T results as a marker of androgen status.

Instant 99mTc-Labelled Glucoheptonate Kit for Kidney Imaging

1983 ◽  
Vol 22 (05) ◽  
pp. 246-250 ◽  
Author(s):  
M. Al-Hilli ◽  
H. M. A. Karim ◽  
M. H. S. Al-Hissoni ◽  
M. N. Jassim ◽  
N. H. Agha
Keyword(s):  
Sodium Hydroxide Solution ◽  
Normal Subjects ◽  
Organ Distribution ◽  
Stable Complex ◽  
Scintillation Camera ◽  
Ph Adjustment ◽  
The Mean ◽  
The Stability ◽  
Kidney Imaging ◽  
Mean Concentration

Gelchromatography column scanning has been used to study the fractions of reduced hydrolyzed 99mTc, 99mTc-pertechnetate and 99mTc-chelate in a 99mTc-glucoheptonate (GH) preparation. A stable high labelling yield of 99mTc-GH complex in the radiopharmaceutical has been obtained with a concentration of 40-50 mg of glucoheptonic acid-calcium salt and not less than 0.45 mg of SnCl2 2 H2O at an optimal pH between 6.5 and 7.0. The stability of the complex has been found significantly affected when sodium hydroxide solution was used for the pH adjustment. However, an alternative procedure for final pH adjustment of the preparation has been investigated providing a stable complex for the usual period of time prior to the injection. The organ distribution and the blood clearance data of 99mTc-GH in rabbits were relatively similar to those reported earlier. The mean concentration of the radiopharmaceutical in both kidneys has been studied in normal subjects for one hour with a scintillation camera and the results were satisfactory.

UPAYA MENINGKATKAN HASIL BELAJAR IPA MELALUI PENGGUNAAN VIDEO PEMBELAJARAN BAGI SISWA KELAS IV DI SDN 187/IV KOTA JAMBI

2015 ◽  
Vol 8 (2) ◽  
pp. 93
Author(s):  
Juniar Siregar
Keyword(s):  
Action Research ◽  
Research Method ◽  
Research Report ◽  
The Third ◽  
The Media ◽  
The Subject ◽  
The Mean ◽  
Classroom Action Research

This study presents a research report on improving students’ Learning results on IPA through Video. The objective was to find out whether students’ learning result improved when they are taught by using Video. It was conducted using classroom action research method. The subject of the study was the Grade IV students of SDN 187/IV Kota Jambi which is located on Jln. Adi Sucipto RT 05 Kecamatan Jambi Selatan, and the number of the students were 21 persons. The instruments used were test. In analyzing the data, the mean of the students’ score for the on fisrt sycle was 65,4 (42,85%) and the mean on cycle two was 68,5 (37,15%) and the mean of the third cycle was 81,4 (100%). Then it can be concluded that the use of video on learning IPA can improve the students’ learning result. It is suggested that teachers should use video as one of the media to improve students’ learning result on IPA.Keywords : IPA, students’ learning result, video

PROGESTERONE IN THE HUMAN PERIPHERAL BLOOD IN THE PREOVULATORY PERIOD OF THE MENSTRUAL CYCLE

1967 ◽  
Vol 55 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Benno Runnebaum ◽  
Josef Zander
Keyword(s):  
Menstrual Cycle ◽  
Corpus Luteum ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Progesterone Concentration ◽  
Plasma Progesterone ◽  
Progesterone Secretion ◽  
Graafian Follicle ◽  
The Mean ◽  
Mean Concentration

ABSTRACT Progesterone was determined and identified in human peripheral blood during the preovulatory period of the menstrual cycle, by combined isotope derivative and recrystallization analysis. The mean concentration of progesterone in 1.095 ml of plasma obtained 9 days before ovulation was 0.084 μg/100 ml. However, the mean concentration of progesterone in 1.122 ml of plasma obtained 4 days before ovulation was 0.279 μg/100 ml. These data demonstrate a source of progesterone secretion other than the corpus luteum. The higher plasma-progesterone concentration 4 days before ovulation may indicate progesterone secretion of the ripening Graafian follicle of the ovary.

Sign in / Sign up

Export Citation Format

Share Document