scholarly journals Effects of Hypertonic Stress on The Fine Structure of Sickled Erythrocytes

Blood ◽  
1970 ◽  
Vol 35 (4) ◽  
pp. 437-446 ◽  
Author(s):  
JAMES G. WHITE
Keyword(s):  
Fine Structure ◽  
Cell Membrane ◽  
Characteristic Feature ◽  
Dominant Factor ◽  
Hypertonic Stress ◽  
Erythrocyte Sickling ◽  
Relationship Of ◽  
The Relationship

Abstract The tendency of polymers of sickled hemoglobin (HbS) to align parallel and equidistant to each other has been pointed out in many investigations, and is considered a characteristic feature of erythrocyte sickling. A previous study on stroma-free solutions of sickled hemoglobin, however, suggested that polymers of HbS preferentially assumed radial rather than parallel relationships. Sickled erythrocytes were exposed to hypertonic stress in the present study in order to observe whether parallel bundles of polymers remained intact after removal of the cell membrane. Bundles of polymers in salicylate damaged sickled cells regularly developed branching and radial configurations similar to those found in stroma-free gels. Rotational stress appears to be the dominant factor influencing the relationship of HbS polymers, and the force generated by that tension may be an important factor in erythrocyte sickling.

scholarly journals DNA AND THE FINE STRUCTURE OF SYNAPTIC CHROMOSOMES IN THE DOMESTIC ROOSTER (GALLUS DOMESTICUS)

1964 ◽  
Vol 23 (1) ◽  
pp. 63-78 ◽  
Author(s):  
James R. Coleman ◽  
Montrose J. Moses
Keyword(s):  
Electron Microscopy ◽  
Heavy Metal ◽  
Fine Structure ◽  
Electron Microscope ◽  
Meiotic Prophase ◽  
Gallus Domesticus ◽  
Feulgen Staining ◽  
Synaptinemal Complex ◽  
Relationship Of ◽  
The Relationship

The indium trichloride method of Watson and Aldridge (38) for staining nucleic acids for electron microscopy was employed to study the relationship of DNA to the structure of the synaptinemal complex in meiotic prophase chromosomes of the domestic rooster. The selectivity of the method was demonstrated in untreated and DNase-digested testis material by comparing the distribution of indium staining in the electron microscope to Feulgen staining and ultraviolet absorption in thicker sections seen with the light microscope. Following staining by indium, DNA was found mainly in the microfibril component of the synaptinemal complex. When DNA was known to have been removed from aldehyde-fixed material by digestion with DNase, indium stainability was also lost. However, staining of the digested material with non-selective heavy metal techniques demonstrated the presence of material other than DNA in the microfibrils and showed that little alteration in appearance of the chromosome resulted from DNA removal. The two dense lateral axial elements of the synaptinemal complex, but not the central one to any extent, also contained DNA, together with non-DNA material.

Fine structure of granulated cells in the posterior cardinal and renal veins of Amia calva L.

1976 ◽  
Vol 54 (6) ◽  
pp. 843-851 ◽  
Author(s):  
John H. Youson
Keyword(s):  
Fine Structure ◽  
Secretory Granules ◽  
Immediate Release ◽  
Nerve Terminals ◽  
Renal Veins ◽  
Subendothelial Space ◽  
Secretory Products ◽  
Amia Calva ◽  
Relationship Of ◽  
The Relationship

Granulated cells located in the walls of the posterior cardinal and renal veins in the holostean fish Amia calva resemble cells of the adrenal medulla of higher vertebrates. The cells all contain similar electron-dense secretory granules, apparently originating from the Golgi apparatus, and are innervated by nerve terminals. These features suggest that the cells are involved in the production and release of catecholamines. The relationship of the cells to the endothelium of the large veins also suggests that the secretory products of the cells reach the circulation by traversing a complex subendothelial space and passing through the fenestrae of the endothelium. This appears to be an efficient means for the immediate release and distribution of catecholamines in this species of fish.

scholarly journals How to control the sexually transmitted diseases in Benjina?: qualitative studies on the practice of prostitution

2019 ◽  
Vol 10 (1) ◽  
pp. 58-66 ◽  
Author(s):  
Agung Dwi Laksono ◽  
Santi Dwiningsih
Keyword(s):  
Sex Workers ◽  
Transmitted Disease ◽  
Customary Law ◽  
Dominant Factor ◽  
Sexually Transmitted ◽  
Positive Law ◽  
Sexual Services ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

Latar Belakang: Prostitusi yang muncul bersamaan dengan industri besar menimbulkan masalah kesehatan, masalah sosial ekonomi, dan budaya. Artikel ini dimaksudkan untuk mengeksplorasi faktor-faktor yang berkaitan dengan praktik prostitusi di Benjina dan mengeksplorasi potensi untuk mengendalikan dampak penyakit penularan melalui hubungan seks. Metode: Penelitian kualitatif ini dilakukan dengan pendekatan etnografi. Wawancara mendalam dan observasi partisipatif dilakukan terhadap 30 informan yang terkait langsung dengan praktik prostitusi di Benjina. Hasil: Tidak ditemukan lokalisasi di Benjina. Praktik pelacuran ditemukan sebagai hal yang biasa di tempat yang disebut rumah karaoke yang menyediakan peralatan menyanyi sederhana, minuman keras, dan layanan seksual. Ada 46 pekerja seks perempuan yang bekerja di 12 rumah karaoke. Faktor ekonomi ditemukan sebagai faktor dominan yang mendorong para pelaku pelacuran, di samping balas dendam. Ada beberapa kendala dalam menggunakan kondom dalam praktik pelacuran ini. Di antara mereka adalah bentuk fisiologi penis yang mengalami modifikasi, dan hubungan pekerja seks khusus dengan kekasih mereka. Ada potensi Sasi yang dapat digunakan sebagai upaya untuk mengendalikan penyakit penularan melalui hubungan seks. Kesimpulan: Sasi sebagai hukum adat berpotensi menjadi hukum positif untuk menerapkan kondomisasi secara keseluruhan di Benjina. Kata kunci: Penyakit menular seksual, pelacuran, hukum adat, Sasi, adat istiadat.   Abstract Background: Prostitution that appears together with massive industry raises health problems, socioeconomic problems, and culture. This article was intended to explore factors related to prostitution practices in Benjina and explore the potential for controlling the impact of sex transmission disease. Methods: This qualitative study was carried out with an ethnographic approach. In-depth interviews and participatory observation were carried out on 30 informants who were directly related to the practice of prostitution in Benjina. Results: No localization was found at Benjina. The practice of prostitution was found to be commonplace in a place called karaoke houses that provided simple singing equipment, liquor, and sexual services. There were 46 female sex workers who worked in 12 karaoke houses. Economic factors were found to be the dominant factor driving the perpetrators of prostitution, in addition to revenge. There are some obstacles to using condoms in this practice. Among them were the forms of penile physiology that experience modification, and the relationship of special sex workers with their lovers. There was a Sasi potential that can be used as an effort to control sex transmission disease. Conclusion: Sasi as a customary law has the potential to be a positive law to implement condomization as a whole in Benjina. Keywords: sexually transmitted disease, prostitution, customary law, Sasi, traditional customs.

Conservatives and “Renewed Russia,” 1907-1914

Slavic Review ◽  
2002 ◽  
Vol 61 (4) ◽  
pp. 762-786 ◽  
Author(s):  
Mikhail Loukianov
Keyword(s):  
World War I ◽  
Characteristic Feature ◽  
Status Quo ◽  
Political Order ◽  
The Political ◽  
World War ◽  
The Third ◽  
The Status ◽  
Relationship Of ◽  
The Relationship

The article analyzes the relationship of conservatives to the political order that arose after the 1905 revolution. It suggests that by the start of World War I, a dissatisfaction with the status quo had become a characteristic feature of Russian conservatism. The archaic formula “orthodoxy, autocracy, nationality” was the quintessential conservative discourse, both for nationalist supporters of conservative reforms and for opponents of any innovation such as Dubrovin’s All-Russian Union of the Russian People. But this formula existed in sharp contradiction to the realities of “renewed Russia.” Conservatives continually underscored the lack of correspondence between reality and their conservative dogma. In conservative circles, the growth of social tensions on the eve of the war was also understood as evidence of the inadequacy of the new political order. Because of this, Russian conservatives did not aspire to preserve the Third of June system and did not try to restore it after February 1917.

scholarly journals Hubungan Higienitas Vagina, Kadar Gula Darah dan Kadar Hormon Estrogen dengan Kejadian Kandidiasis Vaginalis

2018 ◽  
Vol 18 (3) ◽  
pp. 601
Author(s):  
Silfina Indriani ◽  
Netti Suharti ◽  
Almurdi Almurdi
Keyword(s):  
Blood Sugar ◽  
Quantitative Research ◽  
Dominant Factor ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Hormone Levels ◽  
Analytical Research ◽  
Sugar Levels ◽  
Relationship Of ◽  
The Relationship

Candida albicans is a normal flora in several areas of the human body and has opportunistic properties, so that if conditions support, it will be able to transform into pathogens (Ramali and Werdani, 2001). Candida can become pathogenic if there are predisposing factors, one of which is diabetes mellitus (DM), the frequency of underwear replacement (Anindita, 2006) and the use of contraceptives that affect the balance of estrogen hormones (Amelia, 2009). Researchers are interested in discussing the relationship of vaginal hygiene, blood sugar levels and estrogen hormone levels with vaginalis candidiasis.The purpose of this research was to determine the relationship of vaginal hygiene, blood sugar levels and estrogen hormone levels with vaginalis candidiasis.This research is a quantitative research with a type of analytical research studies. The research design used was a cross sectional comparative study. It was carried out at the Bhayangkara Hospital Polyclinic and Padang Pasir Health Center as well as Nanggalo. The population in this research were all women of fertile age who came to the obstetric polyclinic who conducted Visual Acetate Acid (IVA) Inspection. The sample in this research is the population that meets the inclusion and exclusion criteria. The hypothesis of this research is the relationship between vaginal hygiene, blood sugar levels and estrogen hormone with vaginalis candidiasis.There is a relationship between vaginal hygiene, blood sugar levels and estrogen hormone with vaginalis candidiasis.The conclusion of this research is that the dominant factor with vaginalis candidiasis is vaginal hygiene with an OR value of 11.37.

scholarly journals Pajanan pestisida dan kejadian anemia pada petani holtikultura di Garut

2018 ◽  
Vol 32 (7) ◽  
pp. 245 ◽  
Author(s):  
Nella Mutia Arwin ◽  
Suyud Suyud
Keyword(s):  
Pesticide Exposure ◽  
Dominant Factor ◽  
Bivariate Analysis ◽  
P Value ◽  
Cross Sectional ◽  
Future Studies ◽  
Biomarker Testing ◽  
Cross Sectional Design ◽  
Relationship Of ◽  
The Relationship

Pesticide exposure and anemia incidence among horticultural farmers in Cikajang district, Garut in 2016PurposeThis study aimed to determine the relationship of pesticide exposure with anemia.MethodsA cross-sectional design was used in this study. The population in this study were male horticulture farmers domiciled in Cikajang, Garut. A total of 106 farmers were selected as samples and blood samples were taken to determine hemoglobin concentration.ResultsAverage Hb farmer was 16.65 g/dL. Bivariate analysis showed no association between exposure to pesticides which consisted of working period (p = 0.440, OR = 1.944; 95% CI: 0.51 to 7.325), duration of spraying (p = 1.000),  spraying time (p value = 1.000), spraying frequency (p = 1.000, OR = 0.698; 95% CI: 0.091 to 5.334), the dose of pesticides (p = 1.000, OR = 1.244; 95% CI = 0.164 to 9.444), and mixing pesticides (p = 1.000, OR = 1.337; 95% CI: 0.176 to 10.181) with the incidence of anemia. Multivariate analysis showed that working period is the dominant factor affecting the incidence of anemia in horticulture farmers.ConclusionPesticide exposure was not associated with anemia. Therefore, in future studies, it is expected to perform the appropriate biomarker testing to detect the presence of pesticide exposure with the biological effect on the health of farmers.

The Influence of Fixation Upon the Fine Structure of The Z-Disk of Rat Striated Muscle

1970 ◽  
Vol 6 (1) ◽  
pp. 257-276
Author(s):  
D. N. LANDON
Keyword(s):  
Fine Structure ◽  
Osmium Tetroxide ◽  
Striated Muscle ◽  
Square Lattice ◽  
Cross Linking ◽  
Functional Implications ◽  
The Cross ◽  
Relationship Of ◽  
The Relationship ◽  
Lattice Pattern

The fine structure of the Z-disk in rat striated muscle has been found to be dependent upon the manner of its fixation. Material primarily fixed in osmium tetroxide shows a square or ‘woven’ lattice in transverse sections, with a spacing of around 22 nm, and with its axes off-set by 45° from the axes of alignment of the files of I-filaments prior to their entry into the Z-disk. In longitudinal sections the disk may have a zig-zag appearance with individual I-filaments of one sarcomere apparently linked obliquely to 2 or more I-filaments of the next. Transverse sections of Z-disks in muscle primarily fixed in glutaraldehyde show a square-lattice pattern with a spacing of about II nm, its axes coinciding with the axes of alignment of the adjacent I-filaments. In longitudinal sections oblique linkages of the ends of the I-filaments are not seen, and they appear either to interdigitate, or to be longitudinally continuous with those of the next sarcomere. This second fine structure is interpreted as being the consequence of the superimposition of 2 basic square lattices, each of 22-nm period, 50 % out of register along each axis, and each fort-ned from the lateral linkage of the ends of the interdigitating I-filaments with the ends of adjacent filaments from their own sarcomere. The relationship of this postulated structure to the lattice patterns previously described, the nature of the cross-linking material, and some possible functional implications are briefly discussed.

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