scholarly journals Diabetes mellitus among patients attending TB clinics in Dar es Salaam: a descriptive cross-sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Patricia J. Munseri ◽  
Henrika Kimambo ◽  
Kisali Pallangyo

Abstract Background A bi-directional interaction between diabetes mellitus and tuberculosis is well established and has been likened to that between HIV and TB. Whereas HIV screening is standard of care test in sub Saharan Africa TB programs, the same is not true for diabetes mellitus (DM). Sub Saharan Africa, a region with high TB infection rates, is going through an epidemiological transition with rapidly rising prevalence of diabetes. We aimed at characterizing TB patients with DM in order to identify factors associated with TB-DM dual disease among patients attending TB clinics in Dar es Salaam. Methods A cross-sectional study was conducted between September 2016 and January 2017 among patients attending TB clinics in Dar es Salaam. We collected socio-demographic characteristics, anthropometric measurements and screened for diabetes by measuring fasting blood glucose that was followed by a 2 h postprandial glucose for participants with impaired fasting blood glucose. We examined for socio-demographic and clinical factors associated with diabetes using logistic regression analysis. Results Of the 660 enrolled participants with TB, 25 (3.8%) were on treatment for diabetes while 39 (6.1%) and 147 (23%) of the remaining 635 participants were ultimately diagnosed with DM and impaired fasting blood glucose respectively. The overall prevalence of DM was 9.7% (64/660). Independent risk factors for diabetes included: age > 44 years {OR 4.52, 95% CI: [1.28–15.89]}; family history of diabetes {OR 3.42, 95% [CI 1.88–6.21]}. HIV sero-positive TB patients were less likely to have DM compared to those who were HIV sero-negative {OR 0.35, 95% CI [0.17–0.73]}. Conclusions Screening for diabetes should be advocated for TB patients aged above 44 years and/or with a family history of diabetes. HIV sero-negative TB patients were more likely to have DM compared to those who were HIV sero-positive. Further studies are needed to confirm this observation and the underlying factors.

Author(s):  
Priyanka Inaniya ◽  
B S Meena ◽  
Mohan Lal Meena ◽  
Aparna Sharma ◽  
Shalini Rathore

Background: The present study aimed to study the demographic profile women with gestational diabetes mellitus Methods: This hospital based cross-sectional study Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur. Results: Mean age of patients was 27.68 ± 4.4 Yrs. Most of the study subjects in GDM group (54.7%) were Hindu. Study subjects in GDM group were almost equally from rural (50.7%).Most of the study subjects in both GDM group (88%) were housewives. Habit of smoking was found in only 6.7% females in GDM group. Habit of alcohol was found in 4% females in GDM group. Family history of diabetes was seen more in females with GDM (17.3%). Conclusion: This study concluded that the socio demographic factors influence the occurrence of GDM. Keywords: GDM, Age, Gravida


2020 ◽  
Vol 5 (2) ◽  

Background: Hypertension, the global first and third risk for mortality and disease burden respectively, is recording an increment in Sub-Saharan Africa countries. This study aimed to identify prevalence and its associated risk factor of Hypertension in the Assosa town. Objective: To identify prevalence and factors associated with hypertension in the study area to increase it’s prevention and control methods. Methods & materials: Institutional based cross sectional study design with quota non-probability sampling technique was conducted among patients visited OPD units ofAssosa General Hospital (AGH) andAssosa Health Center(AHC) fromMarch to June 2018. All outpatients were included. To collect data, pre-tested structured questionnaire and face to face interviews were used. Components ofstatisticalresearch software SPSS version-21 like frequency table, chi-square test of independence & logistic regression was used to enter, analyze, summarize and characterize disease and associated factors data. Result: The study was conducted among 194 participants(152 from AGH and 42 from AHC) with 102 males and 92 females. Prevalence of hypertension among patients visited outpatient units of Assosa General Hospital and Assosa Health Center was 17.5%, and was slightly highest in male than female. Associated factors for hypertension among patients visited OPD units of AGH & AHC were history of hypertension in the family (CI=95% and COR=4.497(1.133-17.844) and being private employee (CI=95% and COR=0.0017(0.001-0.407). Conclusion & recommendation: Prevalence of HTN in the Assosa town, was low and influenced by some risk factors like work status and previousfamily history of hypertension. Even if usual usage ofsalt and using vegetable oil was not associated factor, being private employee were independent factor of HTN. In-depth study is recommended for further investigation. To increase preventative methods of HTN, health education supported by mass media, illustrative posters and anotherstrategies at every government & non government work sector are recommended.


2020 ◽  
Vol 7 (52) ◽  
pp. 3148-3152
Author(s):  
Labanyabati Pattanaik ◽  
Madhusmita Acharya ◽  
Manoj Kumar Yadav ◽  
Prafulla Kumar Mishra ◽  
Madhab Nayak

BACKGROUND Type 2 diabetes mellitus is a widely prevalent lifestyle disease associated with high morbidity and mortality due to dead end complications like acute coronary syndrome, chronic kidney failure and acute stroke. Diabetes mellitus patients frequently develop problems of dyselectrolytemia which is common among hospitalised patients with decompensated diabetes. But there is little information on the prevalence of electrolyte disturbances among diabetes patients. Our aim is to find out the pattern of dyselectrolytemia among type 2 diabetes patients and to know if there is any association of blood glucose level with dyselectrolytemia. METHODS An analytical cross-sectional study was done among type 2 diabetes patients admitted in the department of medicine. Fasting blood glucose (FBG), glycosylated haemoglobin level (HbA1c), blood sodium (Na+), potassium (K+) and calcium (Ca2+) were analysed. Occurrence of dyselectrolytemia was compared between patients of very much controlled versus uncontrolled blood glucose levels. RESULTS Out of 199 patients included in the study, 112 (56 %) had uncontrolled diabetes mellitus (DM) with HbA1c level > / = 7.0 %. Occurrence of hyponatremia, hypokalaemia, hyperkalaemia, hypocalcaemia and hypercalcemia were 35 %, 13 %, 7 %, 16 % and 2 % respectively. In diabetes patients, hyponatremia was seen more commonly in patients with uncontrolled DM than those with very much controlled blood glucose (52.67 % versus 12.64 %, p < 0.001). The extent of patients with hypokalaemia or hyperkalaemia didn't vary between the two groups. Patients on insulin treatment were more likely to have hyponatremia than noninsulin patients (p < 0.001). CONCLUSIONS Type 2 DM patients specifically those who have uncontrolled diabetes mellitus have an increased chance to develop dyselectrolytemia. The most well-known electrolyte disturbances seen were hyponatremia followed by hypocalcaemia in our study and they were generally predominant among patients with uncontrolled DM. KEYWORDS Type 2 Diabetes, Dyselectrolytemia, Hyperglycaemia, Fasting Blood Glucose, Hyponatremia


Author(s):  
Oumou Hawa Bah ◽  
Boubacar Alpha Diallo ◽  
Aboubacar Fode Momo Soumah ◽  
Boubacar Siddi Diallo

Background: Prevalence studies are still rare in sub-Saharan Africa on perineal tears. We conducted this cross-sectional study in a communal hospital in Guinea-Conakry, with the objective of this study was to determining the prevalence and characteristics of post-obstetric perineal lesions.Methods: All deliveries between March 1st and August 31st, 2014 were reviewed. We included in the analysis all the single deliveries with perineal tears. The Anglo-Saxon classification of perineal tears was used.Results: The prevalence of perineal tears was 5.7% with 5.4% benign lesions and 0.3% severe lesions. We did not register 4th degree lesions. The average age of parturient was 22 years. The majority (96.6%) of parturient had a history of genital mutilation and perineal scarring (60.3%).Conclusions: This prevalence appear low compared to those reported in other studies in Africa and point to the need for more sophisticated studies to have a better estimate of the prevalence of perineal tears in Guinea-Conakry.


2020 ◽  
Vol 18 (2) ◽  
pp. 1847 ◽  
Author(s):  
Abdallah Y. Naser ◽  
Hassan Alwafi ◽  
Zahra Alsairafi

Objective: This study aims to estimate the length of stay and hospitalisation cost of hypoglycaemia, and to identify determinants of variation in the length of stay and hospitalisation cost among individual patients with type 1 or 2 diabetes mellitus.  Methods: A cross-sectional study was conducted using inpatients records for patients with diabetes mellitus who had been hospitalised due to hypoglycaemic events in two private hospitals in Amman, Jordan between January 2009 and May 2017. All hospitalisation costs were inflated to the equivalent costs in 2017. Hospitalisation cost was estimated from the patient’s perspective in Jordanian dinars (JOD). Descriptive analyses and correlation between sociodemographic or clinical characteristics with the cost and length of stay were explored. Predictors of hypoglycaemic hospitalisation cost and length of stay were determined using logistic regression. Results: During the study period a total of 126 patients with diabetes mellitus were hospitalised due to an incident of hypoglycaemia. The mean patient age was 64.2 (SD=19.6) years; half were male. Patients admitted for hypoglycaemia stayed in hospital for a median duration of two days (IQR=2 days). The median cost of hospitalisation for hypoglycaemia was 163.2 JOD (USD 230.1) (IQR=216.3 JOD). We found that the Glasgow coma score was positively associated with length of stay (0.345, p=0.008), and older age was correlated with higher hospitalisation cost (0.207, p=0.02). Patients with a family history of diabetes had higher hospitalisation costs and longer duration of stay (0.306 and 0.275, p<0.05). In addition, being a male patient (0.394, p<0.05) and with an absence of smoking history was associated with longer duration of stay (0.456, p<0.01), but not with higher hospitalisation cost. Conclusions: Costs associated with the incidence of hypoglycaemic events are not low and constitute a large cost component of managing and treating diabetes mellitus. Male patients and patients having a family history of diabetes should receive extra care and education on the prevention of hypoglycaemic events, and a treatment de-intensification approach should be considered if necessary, so we can prevent its associated hospitalisation costs and length of stay.


2015 ◽  
Vol 4 (1) ◽  
pp. 22-29
Author(s):  
Md Yunus Ali ◽  
Maksuda Begum ◽  
Sultan Sobnam Dipu

Objectives: This cross-sectional study was conducted to find out the prevalence of type 2 diabetes and pre-diabetes ((PD) (Impaired fasting glucose-IFG, impaired glucose tolerance-IGT)) and to see the associations with risk factors. Methods: Two villages were randomly selected from rural area of Mymensingh district. 125 study subjects (≥30 years) were selected with systematic procedure but 118 samples were participated in the study. Below 30 years, diagnosed case of diabetes and urban people were excluded from study. Socio-demographic data were collected on a pre-tested interview schedule through face to face interview. DM, PD were interpreted by estimating fasting blood glucose level and 2 hour after 75 gm glucose load. Obesity was assigned by BMI. SPSS program (version 11.5) used for data analysis. Results: Mean age of participants was 46.68 with SD ± 12.698. Female participation (66.9%) was double compare to male, literacy rate was (64.4%) with female illiteracy of 29.67%. House wives (61.9%) were more than other professions. Middle class people were nearly 73%, Poor 14.4%, sedentary life style 11% and depressives 14.4% evident in study. A 20.3% people did laborious works. 17.8% had the family history of diabetes. Smokers (53.4%) were more than the non-smokers. Majority (89.0%) of rural people eat rice thrice a day. Normal BMI 61.0%, underweight 31.4% and 7.6% overweight observed.  Overall prevalence of T2 DM was 11.0% showing increase trend of diabetes compared to 8.6% estimated in 2000 and higher than several studies of home and abroad. Female showed higher prevalence (7.6%) compare to male (P>0.05). The overall prevalence of PD was 16.1% evident in this study. The prevalence of IFG and IGT were 8.5% and 7.6% respectively. Female showed higher prevalence of IFG (5.1%) and IGT (5.9%) than male (P>0.05). House wives showed higher prevalence (5.6%) of DM compare to other professions (P>0.05). Illiterates showed more PD (10.3%) and less DM (1.7%) but literates showed more (9.3%) DM (P >0.05). DM (6.7%) and PD (11.8%) more were among the middle class (P=0.018). A high prevalence of PD (13.6%) and DM (9.3%) noticed among non-sedentary lifestyle (P >0.05). Smoker showed higher DM (8.5%) and PD (11.8%). (P-0.071). Prevalence of PD and DM were high among the people with physically less active (P =0.795). Depressives showed more prevalence of DM (8.5%) and PD (13.5%), (P=0.345). increased frequency of rice eating (P=0.004), people with normal BMI (P=0.081) and family history of DM (P=0.000) showed positive association with diabetes mellitus. CBMJ 2015 January: Vol. 04 No. 01 P: 22-29


2019 ◽  
Vol 6 (1) ◽  
pp. 96
Author(s):  
Saranya Nagalingam ◽  
Vaishnavi Murugaraj

Background: Babies born to mothers with GDM are at increased risk of complications, primarily growth abnormalities and chemical imbalances such as hypoglycemia, GDM is a reversible condition and women who have adequate control of glucose level scan effectively decrease the associated risks and give birth to healthy babies. The objective was to estimate the prevalence and the predictors of gestational diabetes mellitus.Methods: This study was conducted as a cross sectional study among the antenatal mothers at the outpatient department of the rural and urban health centers of the KG hospital and PG institute and its affiliated centers in Coimbatore. The study period was one year and during which 150 antenatal mothers participated in the study.Results: The prevalence of GDM was 76 (9%) and 74 (11%) in rural and urban health centers respectively. The maximum number of GDM Mothers to be 26-30years of age with a peak indicating 42% and 39% of GDM mothers were found to be in primigravida, 48% of GDM mothers were primipara. About 65% of GDM pre-pregnant mothers were overweight according to BMI, 53% of GDM mothers had positive family history of DM. Majority of the study population 100 (67%) had HBA1C less than 6% and the remaining 50 (33%) had more than 6% value. The variables like age, gravida, parity, family history of diabetes, pre-pregnant BMI, history of PCOS, history of hypertension, history of hypothyroidism was compared with the glycaemic status (HBA1C values) and it was found to be statistically significant at P<0.05.Conclusions: The commonest risk factors which increases the incidence of GDM were family history of diabetes mellitus, overweight pre-pregnant BMI, history of PCOS, hypothyroidism, increasing gravidity and parity respectively.


Author(s):  
K Sunil Kumar ◽  
Abhishek Sasidharan

Introduction: Billroth Gastrojejunostomy (GJ) is less invasive surgery as compared to Roux-en-Y Gastric Bypass (RYGB), which is performed for obesity and weight loss. There is sparse data on long term metabolic effects of GJ, which was performed frequently in the past. Aim: To determine the prevalence of obesity, dyslipidemia and Diabetes Mellitus (DM) in patients that had undergone GJ. Materials and Methods: This was a cross-sectional study conducted in the Department of Gastroenterology, Government Medical College, Calicut, Kerala, India, over a period of six years. All patients with history of GJ, done in past 15 years were included in the study. Presence of obesity, DM and dyslipidemia were noted among patients and was compared with their first degree relatives. Patients with family history of diabetes and without first degree relative were excluded from the study. Statistical analysis was performed using Chi-square test for qualitative variables and independent t-test for quantitative variables. Significance level was fixed as p-value of <0.05. Results: A total of 68 patients were studied. Mean age of patients was 64.01±10.2 years with males predominating the population (92.6%). The most common three reasons for presentation in gastroenterology were dyspeptic symptoms 32(47%), evaluation of anaemia 12 (17.6%), and history of malena 10(14.7%). Prevalence of diabetes was significantly less in patients with GJ (2.9% vs 22%). Obesity and dyslipidemia was also common in patients without GJ (7.3%), with p-value <0.05. Conclusion: Prevalence of obesity, DM and dyslipidemia is significantly lower in patients with GJ.


2020 ◽  
Author(s):  
Francois Folefack Kaze ◽  
Seraphin Nguefack ◽  
Constantine Menkoh Asong ◽  
Jules Clement Nguedia Assob ◽  
Jobert Richie Nansseu ◽  
...  

Abstract Background A relationship exists between birth weight (BW) and glomerular filtration rate (GFR) in postnatal kidney. Willing to fill a gap of knowledge in sub-Saharan Africa, we assessed the effect of BW on blood pressure (BP), proteinuria and GFR among Cameroonians children.Methods This was a cross-sectional hospital-based study from January to April 2018 at the Yaounde Gynaeco-Obstetric and Paediatric Hospital (YGOPH). We recruited low BW (LBW) [<2500g], normal BW (NBW) [2500-3999g] and high BW (HBW) [>4000g] children, aged 5-10 years, born and followed-up at YGOPH. We collected socio-demographic, clinical (weight, height, BP), laboratory (proteinuria, creatinine), maternal and birth data. The estimated GFR was calculated using the Schwartz equation.Results We included 80 children (61.2% boys) with 21 (26.2%) LBW, 45 (56.2%) NBW and 14 (15.5%) HBW; the median (interquartile range) age was 7.3 (6.3-8.1) years and 17 (21.2%) were overweight/obese. Two (2.5%) children, all with a NBW (4.4%), had an elevated BP whereas 2 (2.5%) other children, all with a LBW (9.5%), had hypertension (p=0.233). Seven (8.7%) children had proteinuria with 19%, 2.2% and 14.3% having LBW, NBW and HBW, respectively (p=0.051). Equivalent figures were 18 (22.5%), 14.3%, 24.2% and 28.6% for decreased GFR, respectively (p=0.818). There was a trend towards an inverse relationship between BW and BP, proteinuria and GFR (p>0.05). Conclusion Proteinuria is more pronounced in childhood with a history of LBW and HBW while LBW children are more prone to develop hypertension. Regular follow-up is needed to implement early nephroprotective measures among children with abnormal BW.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Bruce Twinamasiko ◽  
Edward Lukenge ◽  
Stella Nabawanga ◽  
Winnie Nansalire ◽  
Lois Kobusingye ◽  
...  

Introduction. Globally, cardiovascular diseases (CVDs) and diabetes constitute over 50% of the noncommunicable disease (NCD) burden and projections indicate Sub-Saharan Africa will experience a larger burden. Urbanization on the continent is contributing to the change in lifestyle such as diet and physical activity, which may increase the risk for CVDs. There is lack of sufficient data from the African continent on hypertension and its association with sedentary lifestyle. Methods. We conducted a cross sectional study in periurban Uganda among adults aged at least 35 years. We administered questions on diet, physical activity, and smoking. We took anthropometric measurements, blood pressure, and fasting blood glucose. Hypertension was defined as systolic BP>=140 and/or diastolic BP>=90 and/or history of hypertension medications. Logistic regression was used to determine the crude and adjusted odds ratios for the factors associated with hypertension. Results. We enrolled 310 participants and 50% were female. The prevalence of systolic hypertension was 24.5%, diastolic hypertension was 31%, obesity was 46%, and diabetes was 9%. Of those with hypertension (n=76), 53 participants (69.7%) were not aware they had high BP. Sedentary lifestyle was significantly associated with hypertension even after adjusting for age and obesity. Conclusion. There is a high prevalence of obesity, hypertension, and diabetes and majority of participants with hypertension are not aware. Participants with a sedentary work style should be targeted for prevention and screening.


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