scholarly journals Objective assessment of alcohol consumption in early pregnancy using phosphatidylethanol: a cross‐sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Leonieke J. Breunis ◽  
Sophie Wassenaar ◽  
Barbara J. Sibbles ◽  
Ab A. Aaldriks ◽  
Hilmar H. Bijma ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Early Pregnancy ◽  
Gestational Age ◽  
Care Provider ◽  
Objective Assessment ◽  
Obstetric Care ◽  
Tertiary Hospital ◽  
Maternal Blood ◽  
Added Value ◽  
Cross Sectional

Abstract Background Alcohol consumption during pregnancy is associated with major birth defects and developmental disabilities. Questionnaires concerning alcohol consumption during pregnancy underestimate alcohol use while the use of a reliable and objective biomarker for alcohol consumption enables more accurate screening. Phosphatidylethanol can detect low levels of alcohol consumption in the previous two weeks. In this study we aimed to biochemically assess the prevalence of alcohol consumption during early pregnancy using phosphatidylethanol in blood and compare this with self-reported alcohol consumption. Methods To evaluate biochemically assessed prevalence of alcohol consumption during early pregnancy using phosphatidylethanol levels, we conducted a prospective, cross-sectional, single center study in the largest tertiary hospital of the Netherlands. All adult pregnant women who were under the care of the obstetric department of the Erasmus MC and who underwent routine blood testing at a gestational age of less than 15 weeks were eligible. No specified informed consent was needed. Results The study was conducted between September 2016 and October 2017. In total, we received 1,002 residual samples of 992 women. After applying in- and exclusion criteria we analyzed 684 samples. Mean gestational age of all included women was 10.3 weeks (SD 1.9). Of these women, 36 (5.3 %) tested positive for phosphatidylethanol, indicating alcohol consumption in the previous two weeks. Of women with a positive phosphatidylethanol test, 89 % (n = 32) did not express alcohol consumption to their obstetric care provider. Conclusions One in nineteen women consumed alcohol during early pregnancy with a high percentage not reporting this use to their obstetric care provider. Questioning alcohol consumption by an obstetric care provider did not successfully identify (hazardous) alcohol consumption. Routine screening with phosphatidylethanol in maternal blood can be of added value to identify women who consume alcohol during pregnancy.

scholarly journals Factors affecting stillbirth: prospective study

2021 ◽  
Vol 10 (3) ◽  
pp. 939
Author(s):  
Balaji Jadhav ◽  
Shweta Avinash Khade ◽  
Ganesh Shinde ◽  
Shilpa Chandan
Keyword(s):  
Antenatal Care ◽  
Gestational Age ◽  
Prospective Observational Study ◽  
Emergency Obstetric Care ◽  
Obstetric Care ◽  
Tertiary Hospital ◽  
Fetal Weight ◽  
Factors Affecting ◽  
Medical Disorders ◽  
Number Of Births

Background: Stillbirth is defined by WHO as the birth of a baby with a birth weight of 500 gm or more, 22 or more completed weeks of gestation or a body length of 25 cm or more, who died before or during labour and birth.Methods: This was prospective observational study of factors affecting stillbirth was conducted in tertiary hospital for a period of 1 year from 1st June 2014 to 31st May 2015. During the study period, 200 parturient of gestational age 28 weeks or more and fetal weight 1000 gm or more with or without medical disorders were included.Results: The total number of births during study period was 11,951. Stillbirth rate in the present study was 16.73 per 1000 births. Most of stillbirths were seen in the antepartum period (76%) when compared to intrapartum period (24%). Maximum stillbirths occurred in gestational age of 36 weeks and above (52%) and fetal weight between 2001-2500 gm (27.50%). Patients with inadequate antenatal care, less than three visits had 86% stillbirths.Conclusions: Proper antenatal care, prompt referral services and availability of emergency obstetric care will provide a pivotal role for reduction of stillbirths.

scholarly journals Gestational Age Specific Postnatal Growth Curves for Singleton Babies in Tertiary Hospital of Western Nepal

2017 ◽  
Vol 56 (207) ◽  
pp. 325-330
Author(s):  
Santosh Pathak ◽  
Nagendra Chaudhary ◽  
Prativa Dhakal ◽  
Shyam Kumar Mahato ◽  
Sandeep Shrestha ◽  
...  
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Economic Status ◽  
Tertiary Care ◽  
Growth Curves ◽  
Tertiary Hospital ◽  
Care Hospital ◽  
Cross Sectional ◽  
Intrauterine Growth ◽  
Geographical Regions

Introduction: Measurement of birth weight (BW), crown heel length (CHL), head circumference (HC) and chest circumference used to assess the intrauterine growth of a baby vary with altitude, race, gender, socio economic status, maternal size, and maternal diseases. The study aimed to construct centile charts for BW, CHL and HC for new born at different gestational ages in western Nepal. Methods:  This was a descriptive cross sectional study done over a period of 15 months in a tertiary care hospital of western Nepal. BW, length, HC and CC were measured within 12-24 hours of birth. Gestational age was estimated from first day of last menstrual period, maternal ultrasonology and New Ballard’s scoring system. Microsoft 2007 Excel and SPSS-16 was used for data analysis. Cole’s Lambda Mu Sigma method was used for constructing centile curves. Results: Out of 2000 babies analysed, 1910 samples were used to construct smoothed intrauterine growth curve of BW, CHL, and HC from 33-42 weeks of gestation. 57.35% (1147) were male, mean gestational age was 38.13 ±2.44 weeks, where 21.5% were preterm and 1.7% post term. The means of BW, CHL, HC and CC were 2744.78 gm, 47.80 cm, 33.18 cm, and 30.20 cm with standard deviations of 528.29, 3.124, 1.78, and 2.35 respectively. These data vary as compared to the Kathmandu data, in case of birth weight for 10th and 90th centiles, and at 90th centile in case of length. Conclusions: This necessitates the update in the existing growth charts and develop in different geographical regions of a country.

scholarly journals Maternity handover in Kerala: a cross sectional study

2018 ◽  
Vol 5 (9) ◽  
pp. 3760 ◽  
Author(s):  
Aadil Sheikh ◽  
Jessica Dunphy ◽  
Claire Humphries ◽  
Christina MacArthur ◽  
Semira Manaseki-Holland
Keyword(s):  
Healthcare Provider ◽  
Tertiary Care ◽  
Obstetric Care ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Community Health Services ◽  
High Rate ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact

Background: The objective of the study was to explore the referral system from the community to hospital obstetric care in Kerala, India.Methods: Cross-sectional study. A total of 206 obstetric inpatients in 3 hospitals in Kerala, India completed an orally-administered questionnaire regarding referral and attitudes towards healthcare information.Results: Among 206 respondents, 19 (9%) had been referred from another healthcare provider.  In multivariate analysis, referral was independently associated with being in a tertiary hospital (p<0.001). At total of 17 referred women received a document containing hand-written notes from their previous healthcare provider. Just 3 of the documents available to view were formal referral documents; others were test results and/or hospital notes. A total of 170 (86%) of the 206 women thought that receiving documents such as referral letters was important; mostly because it helped them understand their condition and explain it to others (91%).Conclusions: A high rate of self-referral (91%) was reported by obstetric inpatients. It appears that some women who are referred do not receive a formal referral document. Participants thought that receiving referral documents was important. A strong health system requires transfer of information between primary and secondary/tertiary care services, which India is seeking to develop. Further research is needed into why women are not accessing community health services and the impact of the content of referral documents on patient care. 

scholarly journals Prevalence of iron deficiency and thalassemia in patients presenting Tertiary Care Hospital.

2020 ◽  
Vol 27 (12) ◽  
pp. 2618-2621
Author(s):  
Nadia Taj ◽  
Saba Javed ◽  
Munazza Munir ◽  
Anam Naz ◽  
Asma Sajid ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Gestational Age ◽  
Tertiary Care ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Contributing Factors ◽  
Cross Sectional ◽  
Iron Deficient ◽  
Tertiary Care Hospitals

Objectives: To find the frequency of iron deficient anemia and thalassemia in anemic patient reporting in tertiary hospital in Multan. Study Design: Cross Sectional study. Setting: Department of Obstetrics and Gynecology in Nishtar Hospital, Multan. Period: 20th October 2018 to 20th April 2019. Material & Method: In this study total 260 females with anemia HB<10.5g/dl were incorporated. Blood of all the patients were collected following the septic measures in CBC vial for counting of hemoglobin and blood investigation serum ferritin [<11ng/ml] and HB electrophoresis HBA [>6]. Gestational age was predicted depending upon last period of menstruation. Results: Age of patients in this study was between 24 to 34 year with the average age of 29.9±2.3 year, average gestational age 33.2±2.11 week, average parity 1.46±1.3. Iron deficient anemia was observed in 88.4 percent patient. Thalassemia was observed in 5.7 percent patient. Conclusion: The results of our study revealed that iron deficiency and thalassemia are significant contributing factors of anemia in patients reporting tertiary care hospitals Multan. General screening for carriers of thalassemia should be provided to all pregnant females attending prenatal care.

scholarly journals Episiotomy and its relationship to various clinical variables that influence its performance

2016 ◽  
Vol 24 (0) ◽  
Author(s):  
Carmen Ballesteros-Meseguer ◽  
César Carrillo-García ◽  
Mariano Meseguer-de-Pedro ◽  
Manuel Canteras-Jordana ◽  
Mª Emilia Martínez-Roche
Keyword(s):  
Risk Factors ◽  
Epidural Analgesia ◽  
Gestational Age ◽  
Lower Incidence ◽  
Maternal Age ◽  
Tertiary Hospital ◽  
Lithotomy Position ◽  
Cross Sectional ◽  
Induced Labor ◽  
Clinical Variables

Objective: to understand the episiotomy rate and its relationship with various clinical variables. Method: a descriptive, cross-sectional, analytic study of 12,093 births in a tertiary hospital. Variables: Parity, gestational age, start of labor, use of epidural analgesia, oxytocin usage, position during fetal explusion, weight of neonate, and completion of birth. The analysis was performed with SPSS 19.0. Results: the global percentage of episiotomies was 50%. The clinical variables that presented a significant association were primiparity (RR=2.98), gestational age >41 weeks (RR=1.2), augmented or induced labor (RR=1.33), epidural analgesia use (RR=1,95), oxytocin use (RR=1.58), lithotomy position during fetal expulsion (RR=6.4), and instrumentation (RR=1.84). Furthermore, maternal age ≥35 years (RR=0.85) and neonatal weight <2500 g (RR=0.8) were associated with a lower incidence of episiotomy. Conclusions: episiotomy is dependent on obstetric interventions performed during labor. If we wish to reduce the episiotomy rate, it will be necessary to bear in mind these risk factors when establishing policies for reducing this procedure.

scholarly journals Alcohol consumption and binge drinking in early pregnancy. A cross-sectional study with data from the Copenhagen Pregnancy Cohort

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Mette Langeland Iversen ◽  
Nina Olsén Sørensen ◽  
Lotte Broberg ◽  
Peter Damm ◽  
Morten Hedegaard ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Binge Drinking ◽  
Early Pregnancy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Pregnancy Cohort

Characteristics and Surgical Success of Patients Presenting for Repair of Genitourinary Fistula in VVF Center of a Tertiary Hospital

2017 ◽  
Vol 31 (1) ◽  
pp. 34-39
Author(s):  
Rowshan Ara ◽  
Abu Taher Mohammad Nurul Amin ◽  
Md Shadiqul Hoque ◽  
Setara Binte Kasem
Keyword(s):  
Success Rate ◽  
Gestational Age ◽  
Surgical Repair ◽  
Mode Of Delivery ◽  
Tertiary Hospital ◽  
P Value ◽  
Fistula Repair ◽  
Cross Sectional ◽  
Genitourinary Fistula ◽  
Successful Repair

Objective(s): To carry out a prospective review of patients who had undergone surgical repair of genitourinary fistula to determine patients’ characteristics and to explore success of surgery in relation to aetilogy of fistula and attempt of surgery.Materials and Methods : This cross-sectional study was carried out in patients attending the Fistula centre in Dhaka Medical College and Hospital (DMCH) from April 27th to July25th, 2013. Out of 47 patients 27 were recruited for this study. Detailed history was taken about socio-demographic character, gestational age, duration of labour, mode of delivery, conduction of labour and foetal outcome. Causes of fistula, information about fistula repair and success rate were noted. Main outcome measures were successful repair and correlation of success with aetiology of fistula, attempt of surgery. Data were analyzed by SPSS package. A p value of <0.5 was considered as significant.Results: Mean age of the patients was 33.73± 10.73 years with a range of 17 to 58 years and mean height was 144.67±3.013cm. Most of the women (66.7%) were from lower social class. The most common fistula 19 (70.37%) was obstetric due to obstructed labour and in 8 (25.93%) cases it was due to consequence of gynaecological surgery. Mean gestational age of the foetus were 38.57±1.409 weeks and duration of labour was 34.83±14.618 hours. Out of 27 patients, 7 had prior fistula repair without success, 4 patients had prior 2 attempts and 3 had previous 3 and 4 attempts. In 21 patients surgical repair was done through vaginal route while 6 required abdominal approach. Local repair was done in 18 (66.67%) cases and grafting was done in 5(18.52%) cases. Fifteen (55.56%) patients had successful repair and success rate was more when it was first attempted (90%) and 20% in repeat attempt but it was statistically significant p<0.05. Success of repair was more when causes of fistula was gynaecological (87.50%) than when it was obstetrical (42.11%), p<0.05.Conclusion: Success of surgery of genitourinary fistula depends upon so many factors. Gynaecological fistula can be repaired more successfully than obstetrical one. First attempt of surgery is the best attempt, so must be done at skilled hand.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(1) : 34-39

scholarly journals The influence of gestational age and birth weight in the clinical assesment of the muscle tone of healthy term and preterm newborns

2005 ◽  
Vol 63 (4) ◽  
pp. 956-962 ◽  
Author(s):  
Edla S. da Silva ◽  
Magda Lahorgue Nunes
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Muscle Tone ◽  
Objective Assessment ◽  
Fixed Time ◽  
Influential Factors ◽  
Cross Sectional ◽  
Postconceptional Age ◽  
Term Newborns ◽  
Preterm Newborns

OBJECTIVE: To evaluate the influence of gestational age (GA) and birth weight (BW) in the clinical assessment of the muscle tone of healthy term and preterm newborns. METHOD: Cross sectional study. The muscle tone of healthy 42 preterm and 47 term newborns was quantified and measured with a goniometer (an instrument for measuring angles) respectively between 7th-14th day of life and 24-48 hours of life. Newborns were grouped according to GA and BW and evaluated at fixed time intervals by one examiner. Preterm newborns were matched to term at 40 weeks postconceptional age (PCA). RESULTS: The evolution of muscle tone in the preterm occurred gradually, following PCA, independent of birth weight. Preterm newborns had lower scores in all muscle tone indicators when compared to term at the first assessment. Differences were observed among preterm small for GA and adequate to GA for the indicator heel to ear (p<0.001). When compared at 40 weeks PCA, except for posture, all other indicators were significantly different (p< 0.001) among groups. CONCLUSION: Prematurity and intrauterine malnutrition are influential factors in some indicators of the newborn muscle tone state. Muscle tone assessment of preterm infants does not seem to be influenced by birth weight, however evolution is clearly related to postconceptional age. When we compared term newborns AGA and SGA it seems to have a clear influence of the birth weight on some indicators of the muscle tone. The use of devices such as the goniometer allows the performance of a more objective assessment of muscle tone and helps to quantify findings.

scholarly journals Frequency of Neonatal Hypoglycemia Among Women Diagnosed with Maternal Hyperglycemia

2021 ◽  
Vol 15 (6) ◽  
pp. 1685-1687
Author(s):  
Humaira Ashraf ◽  
Mehreen Yousaf Rana ◽  
Afra Rehman ◽  
Anila Mahmood
Keyword(s):  
Blood Glucose ◽  
Pregnant Women ◽  
Gestational Age ◽  
Maternal Blood ◽  
Cross Sectional Study ◽  
Neonatal Hypoglycemia ◽  
Cross Sectional ◽  
Glucose Testing ◽  
Maternal Hyperglycemia ◽  
Glucose Estimation

Objective: To determine frequency of neonatal hypoglycemia, in maternal hyperglycemia Subject and Method: This cross-sectional study was conducted at department of Pathology with collaboration of gynae and OBS department of PNS SHIFA Karachi. Study duration was six months from March 2015 to August 2015. All pregnant women who reported at antenatal clinics of PNS SHIFA Hospital and diagnosed as the cases of hyperglycinemia were included in the study. Maternal blood glucose testing was done according to WHO guidelines i.e. fasting sample, ingestion of 75 g glucose, 01 h and 02 h sample for plasma glucose estimation. Neonatal blood glucose was checked immediately after birth by glucometer. All the data was collected via study proforma. Results: A total of 157 pregnant women were studied their average age was 28.20±4.67 years. Caesarean section was done in 62.4% cases and 58.6% babies were males. Neonatal hypoglycemia was observed among 24.8% of the cases. Neonatal hypoglycemia was statistically significant according to gestational age (p- 0.012), while statistically insignificant according to parity (p-0.184). Conclusion: As per study conclusion, the neonatal hypoglycemia was observed to be highly prevalent among neonates of diabetic mothers as 24.8%. It was found to be statistically significant according to gestational age. Keywords: Gestational diabetes mellitus, Neonates, Hypoglycemia

Sign in / Sign up

Export Citation Format

Share Document