scholarly journals Variations in disease burden of laryngeal cancer attributable to alcohol use and smoking in 204 countries or territories, 1990–2019

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qiang-Wei Zhang ◽  
Jing-Yuan Wang ◽  
Xiao-Feng Qiao ◽  
Tong-Li Li ◽  
Xin Li
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Laryngeal Cancer ◽  
Disease Burden ◽  
Temporal Trends ◽  
Developed Countries ◽  
Average Percentage ◽  
Smoking Control ◽  
Global Increase ◽  
Disease Study

Abstract Background Alcohol consumption and smoking are the leading risk factors for laryngeal cancer (LC). Understanding the variations in disease burden of LC attributable to alcohol use and smoking is critical for LC prevention. Methods Disease burden data of LC were retrieved from the Global Burden of Disease Study 2019. We used estimated average percentage change (EAPC) to measure the temporal trends of the age-standardized mortality rate (ASMR) of LC. Results Globally, while the ASMR of LC decreased by 1.49% (95% CI, 1.41–1.57%) per year between 1990 and 2019, the number of deaths from LC has increased 41.0% to 123.4 thousand in 2019. In 2019, 19.4 and 63.5% of total LC-related deaths were attributable to alcohol use and smoking worldwide, respectively. The ASMR of alcohol- and smoking-related LC decreased by 1.78 and 1.93% per year, whereas the corresponding death number has increased 29.2 and 25.1% during this period, respectively. The decreasing trend was more pronounced in developed countries. In some developing countries, such as Guinea and Mongolia, the LC mortality has shown an unfavorable trend. Conclusion The ubiquitous decrease in LC mortality was largely attributed to the smoking control and highlighted the importance of smoking control policies. However, the disease burden of LC remained in increase and more effective strategies are needed to combat the global increase of alcohol consumption.

scholarly journals Temporal trends in incidence and mortality rates of laryngeal cancer at the global, regional and national levels, 1990–2017

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e050387
Author(s):  
Jing-Yuan Wang ◽  
Qiang-Wei Zhang ◽  
Kaixue Wen ◽  
Chen Wang ◽  
Xiaolin Ji ◽  
...  
Keyword(s):  
Laryngeal Cancer ◽  
Disease Burden ◽  
Temporal Trends ◽  
Mortality Rates ◽  
Population Based ◽  
Mortality Data ◽  
Average Percentage ◽  
Incidence And Mortality ◽  
Disease Study ◽  
Incident Cases

ObjectivesLaryngeal cancer is the most prevalent entity of head and neck cancer. Knowing the trends of incidence and mortality of laryngeal cancer is important for the reduction in related disease burden.DesignPopulation-based observational study.Main outcomes and measuresThe incidence and mortality data of laryngeal cancer were retrieved from the Global Burden of Disease study 2017 online database. The estimated average percentage change was used to quantify the trends of laryngeal cancer incidence and mortality at the global, regional and national levels.ResultsGlobally, the numbers of incident cases and deaths due to laryngeal cancer increased 58.7% and 33.9%, respectively, from 1990 to 2017. However, the overall age-standardised incidence rate (ASIR) and age-standardised mortality rate decreased by 0.99% (95% CI 0.83% to 1.14%) and 1.62% (95% CI 1.50% to 1.74%) per year, respectively. These decreases were ubiquitous worldwide. However, unfavourable trends in the ASIR of laryngeal cancer were also observed in a total of 51 developing countries.ConclusionsThe incidence and mortality rates of laryngeal cancer have significantly decreased at the global level and in most countries over the past three decades. The regions that showed an increasing incidence trend deserve more attention.

scholarly journals Trends in alcohol and tobacco use among Brazilian students: 1989 to 2010

2015 ◽  
Vol 49 (0) ◽  
Author(s):  
Zila M Sanchez ◽  
Mariangela Cainelli Oliveira Prado ◽  
Adriana Sanudo ◽  
Elisaldo A Carlini ◽  
Solange A Nappo ◽  
...  
Keyword(s):  
Public Schools ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
Tobacco Use ◽  
Temporal Trends ◽  
World Health ◽  
The Past ◽  
Epidemiological Surveys ◽  
Brazilian Students ◽  
Self Reporting Questionnaire

OBJECTIVE To analyze temporal trends of the prevalence of alcohol and tobacco use among Brazilian students. METHODS We analyzed data published between 1989 and 2010 from five epidemiological surveys on students from the 6th to the 12th grade of public schools from the ten largest state capitals of Brazil. The total sample consisted of 104,104 students and data were collected in classrooms. The same collection tool – a World Health Organization self-reporting questionnaire – and sampling and weighting procedures were used in the five surveys. The Chi-square test for trend was used to compare the prevalence from different years. RESULTS The prevalence of alcohol and tobacco use varied among the years and cities studied. Alcohol consumption decreased in the 10 state capitals (p < 0.001) throughout 21 years. Tobacco use also decreased significantly in eight cities (p < 0.001). The highest prevalence of alcohol use was found in the Southeast region in 1993 (72.8%, in Belo Horizonte) and the lowest one in Belem (30.6%) in 2010. The highest past-year prevalence of tobacco use was found in the South region in 1997 (28.0%, in Curitiba) and the lowest one in the Southeast in 2010 (7.8%, in Sao Paulo). CONCLUSIONS The decreasing trend in the prevalence of tobacco and alcohol use among students detected all over the Country can be related to the successful and comprehensive Brazilian antitobacco and antialcohol policies. Despite these results, the past-year prevalence of alcohol consumption in the past year remained high in all Brazilian regions.

scholarly journals Disease burden of liver cancer attributable to specific etiologies in China from 1990 to 2019: An age-period-cohort analysis

2021 ◽  
Vol 104 (2) ◽  
pp. 003685042110180
Author(s):  
Songxia Yu ◽  
Haowen Wang ◽  
Tingyang Hu ◽  
Chengbo Yu ◽  
Hanbo Liu ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Liver Cancer ◽  
Disease Burden ◽  
Cohort Analysis ◽  
Temporal Trends ◽  
Rapid Decline ◽  
Heavy Alcohol ◽  
Total Liver ◽  
Life Years ◽  
Heavy Alcohol Use

Temporal trends of total liver cancer have been well reported in China, especially the trends caused by hepatitis B (HBV); however, the trends of liver cancer attributable to specific etiologies have rarely been reported in China. Thus, this study aims to describe the temporal trends in the incidence, mortality and DALYs of total and etiology-specific liver cancer in China from 1990 to 2019. We extracted the incidence, mortality and disability-adjusted life years (DALYs) of total and etiology-specific liver cancer in China from 1990 to 2019 from global disease burden (GBD) 2019. We plotted the trends in the age-standardized rates for incidence, mortality, and DALYs using locally weighted regression (LOESS)-smoothed data from 1990 to 2019. The age-standardized rate for the incidence of liver cancer was analyzed with an age-period-cohort method. The age-standardized rates for incidence, death, and DALYs decreased by −58.8%, −63.8%, and −65.6%, respectively, between 1990 and 2019. The age-standardized rates of incidence, mortality, and DALYs of total liver cancer showed similar temporal patterns, presenting an overall decline, with the average annual percentage change (AAPC) ranging from −3.3% to −3.8%. People in the period before 2007 had a higher risk, and people after 2007 had a lower risk. The cohort risk ratios (RRs) showed decreasing patterns, with the most rapid decline observed in the 1910 to 1960 cohorts. Our study generally revealed favorable decreasing trends for total and etiology-specific liver cancer in China from 1990 to 2019. Despite the overall decline in liver cancer due to heavy alcohol use and obesity from 1990 to 2019, there have been apparent upward trends since 2006. Planned population-wide interventions targeting heavy alcohol use and obesity may mitigate the increasing trends in liver cancer attributable to alcohol use and NASH.

Cheers together, but not alone: Peer drinking moderates alcohol consumption following interpersonal stress

2021 ◽  
pp. 026540752199604
Author(s):  
Hannah R. Hamilton ◽  
Stephen Armeli ◽  
Howard Tennen
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Academic Stress ◽  
Interpersonal Stress ◽  
Need To Belong ◽  
Effective Strategy ◽  
Social Drinking ◽  
Interpersonal Stressors ◽  
Peer Drinking

In view of the importance of the need to belong in motivating behavior, we examined whether interpersonal and academic stress differentially influence social and solitary alcohol consumption and whether social and solitary alcohol consumption differentially predict next-day interpersonal and academic stress. Based on research suggesting that drinking with friends is related to increased alcohol consumption following belongingness threat, we also examined whether peer consumption moderates associations between daily interpersonal stress and social drinking. Each day for 30 days, 1641 undergraduates reported stress, alcohol consumption, and peer consumption. Academic stress was related to lower levels of social and solitary alcohol consumption. Interpersonal stress was associated with greater social alcohol consumption, but only when students reported being around others who were drinking greater than average peer quantities. However, although social drinking was related to lower next-day academic stress, it was unrelated to next-day interpersonal stress. Findings are consistent with the notion that individuals’ perceptions of peers’ alcohol use might serve as a signal to join in this behavior to reduce belongingness threats associated with interpersonal stressors, although this may not be an effective strategy.

scholarly journals Inequalities in the Global Burden of Chronic Kidney Disease Due to Type 2 Diabetes Mellitus: An Analysis of Trends from 1990 to 2019

2021 ◽  
Vol 18 (9) ◽  
pp. 4723
Author(s):  
Nóra Kovács ◽  
Attila Nagy ◽  
Viktor Dombrádi ◽  
Klára Bíró
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Chronic Kidney Disease ◽  
Type 2 Diabetes Mellitus ◽  
Kidney Disease ◽  
Data Exchange ◽  
Disease Burden ◽  
Socioeconomic Development ◽  
Developed Countries

The prevalence of type 2 diabetes mellitus (T2DM) and the burden of complications are increasing worldwide. Chronic kidney disease (CKD) is one serious complication. Our aim was to investigate the trends and inequalities of the burden of CKD due to T2DM between 1990 and 2019. Data were obtained from the Global Health Data Exchange database. Age-standardized incidence, mortality, and DALYs rates of CKD were used to estimate the disease burden across the Human Development Index (HDI). Joinpoint regression was performed to assess changes in trend, and the Gini coefficient was used to assess health inequality. A higher incidence was observed in more developed countries (p < 0.001), while higher mortality and DALYs rates were experienced in low and middle HDI countries in 2019 (p < 0.001). The trend of incidence has increased since 1990 (AAPC: 0.9–1.5%), while slight decrease was observed in low HDI countries in mortality (APC: −0.1%) and DALYs (APC: −0.2%). The Gini coefficients of CKD incidence decreased from 0.25 in 2006 to 0.23 in 2019. The socioeconomic development was associated with disease burden. Our findings indicate that awareness of complications should be improved in countries with high incidence, and cost-effective preventive, diagnostic, and therapeutic tools are necessary to implement in less developed regions.

scholarly journals Alcohol Use Disorder among Patients Suffered from Road Collisions in a Vietnamese Delta Province

2019 ◽  
Vol 16 (13) ◽  
pp. 2423 ◽  
Author(s):  
Hai Minh Vu ◽  
Tung Thanh Tran ◽  
Giang Thu Vu ◽  
Cuong Tat Nguyen ◽  
Chau Minh Nguyen ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Drinking Behavior ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Problematic Drinking ◽  
Current Context ◽  
Educational Campaign ◽  
Causes Of Deaths ◽  
The Relationship

Traffic collisions have continuously been ranked amongst the top causes of deaths in Vietnam. In particular, drinking has been recognized as a major factor amplifying the likelihood of traffic collisions in various settings. This study aims to examine the relationship between alcohol use and traffic collisions in the current context of Vietnam. A cross-sectional study was conducted on 413 traffic collisions patients in six health facilities in the Thai Binh Province to investigate the level of alcohol consumption and identify factors influencing alcohol use among these patients. The Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) scale was used to determine the problematic drinking behavior of the participants. The percentage of patients having problematic drinking was more than 30%. Being male, having a high household income, and working as farmer/worker were risk factors for alcohol abuse. People causing accidents and patients with a traumatic brain injury had a higher likelihood of drinking alcohol before the accidents. This study highlights the necessity of more stringent laws on reducing drink-driving in Vietnam. In addition, more interventions, especially those utilizing mass media like educational campaign of good behavior on social networks, are necessary to reduce alcohol consumption in targeted populations in order to decrease the prevalence and burden of road injuries.

Nalmefene against alcohol use disorder: A report of one case

2017 ◽  
Vol 41 (S1) ◽  
pp. s866-s866
Author(s):  
M. Juncal Ruiz ◽  
O. Porta Olivares ◽  
L. Sánchez Blanco ◽  
R. Landera Rodríguez ◽  
M. Gómez Revuelta ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Opioid Receptor ◽  
Treatment Option ◽  
Withdrawal Syndrome ◽  
Alcohol Use Disorder ◽  
Alcohol Intake ◽  
Family Relationship ◽  
Heavy Drinking ◽  
Alcohol Withdrawal Syndrome

IntroductionAlcohol consumption represents a significant factor for mortality in the world: 6.3% in men and 1.1% in women. Alcohol use disorder is also very common: 5.4% in men and 1.5% in women. Despite its high frequency and the seriousness of this disorder, only 8% of all alcohol-dependents are ever treated. One potentially interesting treatment option is oriented toward reducing alcohol intake.AimsTo describe one case who has improved his alcohol consumption after starting treatment with nalmefene, an opioid receptor antagonist related to naltrexone.MethodsA 35-year-old male with alcohol use disorder since 2001 came to our consult in November 2015. He was in trouble with his family and he had a liver failure. We offer a new treatment option with nalmefene 18 mg to reduce alcohol consumption.ResultsBefore to start nalmefene he drank 21 drinks/week. Six-month later, he decreased alcohol intake until 5 drinks/week with better family relationship and liver function. After starting nalmefene he complained of nausea, so we recommend to take the middle of the pill for next 7 days. After this time he returned to take one pill with good tolerance and no more side effects or withdrawal syndrome.ConclusionsNalmefene appears to be effective and safe in reducing heavy drinking and in preventing alcohol withdrawal syndrome due to its opioid receptor antagonism. This case suggests nalmefene is a potential option to help patients, who do not want or cannot get the abstinence, in reducing their alcohol consumption.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Towards the characterization and validation of alcohol use disorder subtypes: integrating consumption and symptom data

2013 ◽  
Vol 44 (1) ◽  
pp. 143-159 ◽  
Author(s):  
K. M. Jackson ◽  
K. K. Bucholz ◽  
P. K. Wood ◽  
D. Steinley ◽  
J. D. Grant ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Model Comparison ◽  
Latent Class ◽  
Common Factor ◽  
Hybrid Approaches ◽  
Epidemiologic Survey ◽  
Alcohol Involvement ◽  
Best Fitting

BackgroundThere is evidence that measures of alcohol consumption, dependence and abuse are valid indicators of qualitatively different subtypes of alcohol involvement yet also fall along a continuum. The present study attempts to resolve the extent to which variations in alcohol involvement reflect a difference in kindversusa difference in degree.MethodData were taken from the 2001–2002 National Epidemiologic Survey of Alcohol and Related Conditions. The sample (51% male; 72% white/non-Hispanic) included respondents reporting past 12-month drinking at both waves (wave 1:n = 33644; wave 2:n = 25186). We compared factor mixture models (FMMs), a hybrid of common factor analysis (FA) and latent class analysis (LCA), against FA and LCA models using past 12-month alcohol use disorder (AUD) criteria and five indicators of alcohol consumption reflecting frequency and heaviness of drinking.ResultsModel comparison revealed that the best-fitting model at wave 1 was a one-factor four-class FMM, with classes primarily varying across dependence and consumption indices. The model was replicated using wave 2 data, and validated against AUD and dependence diagnoses. Class stability from waves 1 to 2 was moderate, with greatest agreement for the infrequent drinking class. Within-class associations in the underlying latent factor also revealed modest agreement over time.ConclusionsThere is evidence that alcohol involvement can be considered both categorical and continuous, with responses reduced to four patterns that quantitatively vary along a single dimension. Nosologists may consider hybrid approaches involving groups that vary in pattern of consumption and dependence symptomatology as well as variation of severity within group.

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