Clinical and epidemiological features of heart-hand syndrome, an updated analysis in China

Abstract Background The purpose of this study was to prospectively recruit patients treated with limb malformation and to explore the prevalence and the clinical and epidemiological features of Heart-Hand Syndrome (HHS) in China. Methods The consecutive patients treated for congenital upper limb malformation in Beijing Ji Shui Tan Hospital from October 1st, 2016 to October 1st, 2019 were prospectively recruited. We reviewed the patients’ medical records and identified patients with abnormal electrocardiogram (ECG) and/or abnormal ultrasonic cardiogram as well as their basic demographic and clinical characteristics. Results A total 1653 (1053 male and 600 female) patients with congenital upper extremity malformations were prospectively recruited. Among them, 200 (12.1%) had abnormal ultrasonic cardiogram (181patients, 10.9%) and/or abnormal ECG (19 patients, 1.1%). The commonest type of abnormal heart structure was atrial septal defect (69/181 38.1%), and the commonest abnormal ECG was wave patterns (7/19, 36.8%). HHS patients had a higher comorbidity rate (11%) than non-HHS patients (6.9%). Patients with HHS were classified into four groups by the types of congenital upper extremity malformations, among which the most common group was thumb type (121/200, 60.5%). Conclusions HHS occurred frequently among patients with congenital upper extremity malformation in China, particularly for those with multiple congenital malformations. The commonest type of hand malformations of HHS patients was thumb malformation.

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Assessment of Risk Factors for Severe Coronavirus Disease 2019 among Iranian Patients

10.32592/ircmj.2020.22.9.72 ◽

2020 ◽

Keyword(s):

Risk Factors ◽

Immune System ◽

Medical Records ◽

Critical Role ◽

Diabetic Patients ◽

Medication History ◽

Epidemiological Features ◽

Hookah Smoking ◽

And Behavior ◽

Iranian Patients

Background: The outbreak of Coronavirus Disease 2019 (COVID-19) has led to a major concern for those who are more vulnerable to infections. Objectives: This study aimed to evaluate the most important risk factors for severe COVID-19 pneumonia. Methods: This retrospective study included information on clinical and epidemiological features of 105 patients with severe COVID-19 pneumonia hospitalized in Tajrish Hospital, Tehran, Iran. Initially, the medical records of the patients were investigated, and an interview was conducted based on a pre-prepared checklist to seek information about symptoms, past medical history, medication history, and behavior before hospitalization. Results: Out of 105 participants, 76 (72.5%) cases were male, and 54 (51.4%) patients were older than 54 years old. The majority of the patients (n=18; 17.1%) had both hypertension and diabetes (n=12; 11.4%). Metformin (n=36; 34.3%) was the most used medication amongst the studied patient. In addition, 24 (22.9%) patients were recreational hookah smokers, and the majority (75%) of them were under the age of 46 years old. Eventually, 19 patients were excluded from the study, of whom 11 individuals had diabetes, and 10 cases were using metformin. Conclusion: Apparently, hookah smoking played a critical role in the spread of COVID-19 in Iran and has made younger people more susceptible. In addition to older age, the immunosuppressive effects of Metformin seem to make diabetic patients with an impaired immune system more vulnerable to severe COVID-19 pneumonia. More studies on the immune system of vulnerable individuals by identifying their differences can help to protect them.

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Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province

BMC Infectious Diseases ◽

10.1186/s12879-021-05825-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Wen Wang ◽

Lei Chen ◽

Qiao He ◽

Mingqi Wang ◽

Mei Liu ◽

...

Keyword(s):

Mechanical Ventilation ◽

Clinical Features ◽

Medical Records ◽

Clinical Characteristics ◽

Sichuan Province ◽

Chest Ct ◽

Shortness Of Breath ◽

Course Of Disease ◽

West China ◽

Radiologic Abnormality

Abstract Background The outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences between severe versus non-severe patients. Methods Patients admitted for COVID-19 between January 21 and February 11 from fifteen hospitals in Sichuan Province, China were included. Experienced clinicians trained with methods abstracted data from medical records using pre-defined, pilot-tested forms. Clinical characteristics between severe and non-severe patients were compared. Results Of the 169 patients included, 147 were laboratory-confirmed, 22 were suspected. For confirmed cases, the most common symptoms from onset to admission were cough (70·7%), fever (70·5%) and sputum (33·3%), and the most common chest CT patterns were patchy or stripes shadowing (78·0%); throughout the course of disease, 19·0% had no fever, and 12·4% had no radiologic abnormality; twelve (8·2%) received mechanical ventilation, four (2·7%) were transferred to ICU, and no death occurred. Compared to non-severe cases, severe ones were more likely to have underlying comorbidities (62·5% vs 26·2%, P = 0·001), to present with cough (92·0% vs 66·4%, P = 0·02), sputum (60·0% vs 27·9%, P = 0·004) and shortness of breath (40·0% vs 8·2%, P < 0·0001), and to have more frequent lymphopenia (79·2% vs 43·7%, P = 0·003) and eosinopenia (84·2% vs 57·0%, P = 0·046). Conclusions The symptoms of patients in west China were relatively mild, and an appreciable proportion of infected cases had no fever, warranting special attention.

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A triple combination of treatments on moderate COVID-19

Open Medicine ◽

10.1515/med-2021-0279 ◽

2021 ◽

Vol 16 (1) ◽

pp. 769-772

Author(s):

ChunMiao Bao ◽

BinBin Li ◽

YuFeng Zhou

Keyword(s):

Medical Records ◽

Clinical Characteristics ◽

Smoking Status ◽

Length Of Hospital Stay ◽

Convincing Evidence ◽

Triple Combination ◽

Viral Shedding ◽

Null Effect ◽

Treatment Start

Abstract Objective A triple combination of interferon (IFN) α-2b, lopinavir tablets, and umifenovir was used to treat COVID-19 patients. It is important to explore whether the benefit of this therapy is time dependent. Methods A cohort of moderate COVID-19 patients (n = 54) was admitted for hospitalization. The demographic (age, gender, and smoking status) and clinical characteristics (epidemiological trace and comorbidity) were collected from the digital medical records. The length of hospital stay (LOS) and the viral shedding time (VST) were set as the outcomes for COVID-19 cases. Results After control for age, sex, epidemiological trace, smoking, and comorbidity, the time of treatment start had null effect on VST (IRR = 1.09; 95% CI = 0.91–1.30; p = 0.33) or LOS (IRR = 1.10; 95% CI = 0.94–1.28; p = 0.23). Conclusion There is no convincing evidence to support a pivotal role of the timing of the therapy in the prognosis of moderate COVID-19 cases.

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COVID-19 outbreak in Jordan: Epidemiological features, clinical characteristics, and laboratory findings

Annals of Medicine and Surgery ◽

10.1016/j.amsu.2020.07.020 ◽

2020 ◽

Vol 57 ◽

pp. 103-108 ◽

Cited By ~ 3

Author(s):

Shaher M. Samrah ◽

Abdel-Hameed W. Al-Mistarehi ◽

Ali M. Ibnian ◽

Liqaa A. Raffee ◽

Suleiman M. Momany ◽

...

Keyword(s):

Clinical Characteristics ◽

Laboratory Findings ◽

Epidemiological Features

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Clinical characteristics and outcome of vasculitides

Journal of Patan Academy of Health Sciences ◽

10.3126/jpahs.v3i2.20267 ◽

2016 ◽

Vol 3 (2) ◽

pp. 3-9

Author(s):

Buddhi Prasad Paudyal ◽

Anjana Education Rajbhandari

Keyword(s):

Medical Records ◽

Clinical Characteristics ◽

Cross Sectional Study ◽

Health Sciences ◽

Small Vessel ◽

Small Vessel Vasculitis ◽

Cross Sectional ◽

The Mean ◽

Schonlein Purpura ◽

Overall Mortality

Introductions: Vasculitides can cause significant morbidity and mortality if not treated on time. There is lack of data locally. This study aims to define the pattern, clinical characteristics, and outcome of vasculitides.Methods: This was a cross sectional study between January 2011 and December 2015 at Patan Hospital, Patan Academy of Health Sciences, Lalitpur, Nepal. The medical records of patients diagnosed with vasculitides in adults rheumatology service of the hospital were reviewed.Results: Ninety six patients were diagnosed with vasculitides during the study period. The mean age was 42.2 years. Sixty nine (71.8%) patient had small vessel, 20 (20.8%) large vessel and five (5.2%) had variable vessel vasculitides. Seventy five patients (78.1%) had primary and 21 (21.8%) secondary vasculitides. Cutaneous leucocytoclasticangitis was seen in 27 (28.1%), Takayasu arteritis in 17 (17.7), Henoch-Schonlein purpura in 11 (11.4%) and Rheumatoid arthritis associated vasculitis in nine patients. Purpura was present in all 96 (100%). The overall mortality was 9 (9.3%).Conclusions: Primary vasculitides were more common than secondary forms. Small vessel vasculitis was the most common. Cutaneous symptoms were predominant features. The mortality was attributed to active disease, sepsis, and complications of the primary disease. Journal of Patan Academy of Health Sciences. 2016 Dec;3(2):3-9

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Comparing the Clinical Characteristics and Mortality of Residential and Non-Residential Older People with COVID-19: Retrospective Observational Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph19010483 ◽

2022 ◽

Vol 19 (1) ◽

pp. 483

Author(s):

Francesc X. Marin-Gomez ◽

Jacobo Mendioroz-Peña ◽

Miguel-Angel Mayer ◽

Leonardo Méndez-Boo ◽

Núria Mora ◽

...

Keyword(s):

Risk Factors ◽

Electronic Medical Records ◽

Medical Records ◽

Clinical Characteristics ◽

Fold Increase ◽

The Elderly ◽

Health Administration ◽

Epidemic Outbreak ◽

Risk Of Death ◽

Using Data

Nursing homes have accounted for a significant part of SARS-CoV-2 mortality, causing great social alarm. Using data collected from electronic medical records of 1,319,839 institutionalised and non-institutionalised persons ≥ 65 years, the present study investigated the epidemiology and differential characteristics between these two population groups. Our results showed that the form of presentation of the epidemic outbreak, as well as some risk factors, are different among the elderly institutionalised population with respect to those who are not. In addition to a twenty-fold increase in the rate of adjusted mortality among institutionalised individuals, the peak incidence was delayed by approximately three weeks. Having dementia was shown to be a risk factor for death, and, unlike the non-institutionalised group, neither obesity nor age were shown to be significantly associated with the risk of death among the institutionalised. These differential characteristics should be able to guide the actions to be taken by the health administration in the event of a similar infectious situation among institutionalised elderly people.

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RETROSPECTIVE ANALYSIS OF LEPTOSPIROSIS MORBIDITY IN IVANO-FRANKIVSK REGION (EPIDEMIOLOGICAL AND CLINICAL CHARACTERISTICS)

Wiadomości Lekarskie ◽

10.36740/wlek202007117 ◽

2020 ◽

Vol 73 (7) ◽

pp. 1397-1401

Author(s):

Oleksandra Ya. Pryshliak ◽

Tetiana O. Nikiforova ◽

Zoriana R. Tylishchak ◽

Oleksandr P. Boichuk ◽

Nadiya V. Vaskul ◽

...

Keyword(s):

Retrospective Analysis ◽

Medical Records ◽

Clinical Characteristics ◽

Clinical Observation ◽

State Enterprise ◽

Winter Period ◽

Prognostic Features ◽

The Past ◽

Regional Laboratory ◽

High Virulence

The aim: To perform a retrospective analysis of leptospirosis morbidity in Ivano-Frankivsk region, to give the etiological characteristics of leptospirosis according to clinicallaboratory parameters, to determine the peculiarities of the course, prognostic features. Materials and methods: Data of the State Enterprise “Ivano-Frankivsk Regional Laboratory Center of the Ministry of Health of Ukraine”, reports and abstracts of medical records of the Regional Clinical Infectious Diseases Hospital for 2009-2018 were used. Clinical observation of patients, analysis of general-clinical, biochemical, and serological indices were carried out. Results: The leptospirosis morbidity in Ivano-Frankivsk region during 2009-2018 was higher than in general in Ukraine. Activation of foci of leptospirosis L. pomona and grippotyphosa in 2009-2013, decrease of L. grippotyphosa and increase of L. pomona foci and “new” L. autumnalis, australis, bataviae, cynopteri in 2014-2018 were noted. The emergence of leptospirosis L. autumnalis, which had a high virulence and caused a severe course, was noted. Conclusions: The leptospirosis morbidity in the Ivano-Frankivsk region over the past 10 years has exceeded the incidence in Ukraine and varied within 0.62-2.2 per 100,000. During the last 5 years, the serological structure has changed: L. pomona (27.7%) prevailed, L. grippotyphosa decreased (2.1%), L. bataviae and cynopteri, autumnalis increased (by 8.5%). Seasonality is shifted in the autumn-winter period (November-February) (L. grippotyphosa, australis, pomona, canicola). According to forecasts, leptospirosis induced by L. autumnalis was most adverse. Leptospiroses of serogroups L. australis, bataviae, cynopteri had a mild course, there were fewer complications.

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Completeness of Pediatric TB Reporting in New York City

Public Health Reports ◽

10.1093/phr/118.2.144 ◽

2003 ◽

Vol 118 (2) ◽

pp. 144-153 ◽

Cited By ~ 4

Author(s):

Pablo San Gabriel ◽

Lisa Saiman ◽

Katherine Kaye ◽

Muriel Silin ◽

Ida Onorato ◽

...

Keyword(s):

New York ◽

New York City ◽

York City ◽

Medical Records ◽

Clinical Characteristics ◽

Gastric Aspirate ◽

Department Of Health ◽

Recent Transmission ◽

Pediatric Tb ◽

Completeness Of Reporting

Objectives. Accurate surveillance of tuberculosis (TB) in children is critical because such cases represent recent transmission, but surveillance is difficult as only 10% to 50% of cases are culture-confirmed. Hospital-based sources were used to develop alternative surveillance to assess completeness of reporting for pediatric TB in northern Manhattan and Harlem from 1993 through 1995. Methods. Alternative surveillance sources included ICD-9-CM hospital discharge codes for active TB and gastric aspirate reports. Cases identified by alternative surveillance were compared with cases previously reported to the New York City Department of Health (NYC DOH). Results. Alternative surveillance detected 25 cases of possible pediatric TB, of which four (16%) had never been reported to the NYC DOH and three (12%) had been reported as suspect cases, but had not fulfilled the criteria for a reportable case of pediatric TB. Of these seven newly counted cases, three were detected by ICD-9-CM codes, three by a gastric aspirate log book, and one by both. In contrast, 13 other cases had been reported to the NYC DOH, but were undetected by our alternative surveillance; eight of these could be verified with available medical records. Thus, the demographic and clinical characteristics of the 25 detected and the eight undetected cases with available medical records were evaluated in this study. Conclusions. Alternative surveillance proved effective, was complementary to the NYC DOH surveillance efforts, and increased the number of pediatric TB cases identified during the study period by 21%.

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Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20190108 ◽

2019 ◽

Vol 77 (9) ◽

pp. 632-637

Author(s):

Danyelle Sadala Reges ◽

Marcela Mazzeo ◽

Rafael Rosalino ◽

Vivian Dias Baptista Gagliardi ◽

Leandro Gama Cerqueira ◽

...

Keyword(s):

Medical Records ◽

Clinical Characteristics ◽

Rare Event ◽

Clinical Results ◽

Medical Professional ◽

Arterial Dissection ◽

Common Risk Factor ◽

Patients Âgés ◽

Number Of Patients ◽

Using Data

ABSTRACT Cervical arterial dissection accounts for only a small proportion of ischemic stroke but arouses scientific interest due to its wide clinical variability. Objective: This study aimed to evaluate its risk factors, outline its clinical characteristics, compare treatment with antiaggregation or anticoagulation, and explore the prognosis of patients with cervical arterial dissection. Methods: An observational, retrospective study using data from medical records on patients with cervical arterial dissection between January 2010 and August 2015. Results: The total number of patients was 41. The patients' ages ranged from 19 to 75 years, with an average of 44.5 years. The most common risk factor was smoking. Antiaggregation was used in the majority of patients (65.5%); 43% of all patients recanalized in six months, more frequently in patients who had received anticoagulation (p = 0.04). Conclusion: The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.

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Are clinical characteristics associated with upper-extremity hypertonia in severe ischaemic supratentorial stroke?

Acta Dermato Venereologica ◽

10.2340/16501977-0009 ◽

2007 ◽

Vol 39 (1) ◽

pp. 33-37 ◽

Cited By ~ 15

Author(s):

AA van Kuijk ◽

HT Hendricks ◽

JW Pasman ◽

BH Kremer ◽

AC Geurts

Keyword(s):

Upper Extremity ◽

Clinical Characteristics

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