scholarly journals Age estimation based on Willems method versus country specific model in Saudi Arabia children and adolescents

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ali Alqerban ◽  
Muath Alrashed ◽  
Ziyad Alaskar ◽  
Khalid Alqahtani
Keyword(s):  
Children And Adolescents ◽  
Mean Absolute Error ◽  
Absolute Error ◽  
Specific Model ◽  
Permanent Teeth ◽  
Dental Age ◽  
Mean Error ◽  
Significant Difference ◽  
The Difference ◽  
Mandibular Teeth

Abstract Background The aims of this study were to create a method for estimation of dental age in Saudi children and adolescents based on the Willems model developed using the Belgian Caucasian (BC) reference data and to compare the ability of the two models to predict age in Saudi children. Methods Development of the seven lower left permanent mandibular teeth was staged in 1146 panoramic radiographs from healthy Saudi children (605 male, 541 female) without missing permanent teeth and without all permanent teeth fully developed (except third molars). The data were used to validate the Willems BC model and to construct a Saudi Arabian-specific (Willems SA) model. The mean error, mean absolute error, and root mean square error obtained from both validations were compared to quantify the variance in errors in the sample. Results The overall mean error for the Willems SA method was 0.023 years (standard deviation, ± 0.55), indicating no systematic underestimation or overestimation of age. For girls, the error using the Willems SA method was significantly lower but still negligible at 0.06 years. A small but statistically significant difference in total mean absolute error (11 days) was found between the Willems BC and Willems SA models when the data were compared independent of sex. The overall mean absolute error for girls was slightly lower for the Willems BC method than for the Willems SA method (1.33 years vs. 1.37 years). Conclusions The difference in ability to predict dental age between the Willems BC and Willems SA methods is very small, indicating that the data from the BC population can be used as a reference in the Saudi population.

scholarly journals The Effect of Training Sample Size on the Prediction of White Matter Hyperintensity Volume in a Healthy Population Using BIANCA

2022 ◽  
Vol 13 ◽  
Author(s):  
Niklas Wulms ◽  
Lea Redmann ◽  
Christine Herpertz ◽  
Nadine Bonberg ◽  
Klaus Berger ◽  
...  
Keyword(s):  
White Matter ◽  
Sample Size ◽  
Mean Absolute Error ◽  
External Validation ◽  
Similarity Index ◽  
Absolute Error ◽  
Training Sample ◽  
White Matter Hyperintensity ◽  
Training Sample Size ◽  
The Difference

Introduction: White matter hyperintensities of presumed vascular origin (WMH) are an important magnetic resonance imaging marker of cerebral small vessel disease and are associated with cognitive decline, stroke, and mortality. Their relevance in healthy individuals, however, is less clear. This is partly due to the methodological challenge of accurately measuring rare and small WMH with automated segmentation programs. In this study, we tested whether WMH volumetry with FMRIB software library v6.0 (FSL; https://fsl.fmrib.ox.ac.uk/fsl/fslwiki) Brain Intensity AbNormality Classification Algorithm (BIANCA), a customizable and trainable algorithm that quantifies WMH volume based on individual data training sets, can be optimized for a normal aging population.Methods: We evaluated the effect of varying training sample sizes on the accuracy and the robustness of the predicted white matter hyperintensity volume in a population (n = 201) with a low prevalence of confluent WMH and a substantial proportion of participants without WMH. BIANCA was trained with seven different sample sizes between 10 and 40 with increments of 5. For each sample size, 100 random samples of T1w and FLAIR images were drawn and trained with manually delineated masks. For validation, we defined an internal and external validation set and compared the mean absolute error, resulting from the difference between manually delineated and predicted WMH volumes for each set. For spatial overlap, we calculated the Dice similarity index (SI) for the external validation cohort.Results: The study population had a median WMH volume of 0.34 ml (IQR of 1.6 ml) and included n = 28 (18%) participants without any WMH. The mean absolute error of the difference between BIANCA prediction and manually delineated masks was minimized and became more robust with an increasing number of training participants. The lowest mean absolute error of 0.05 ml (SD of 0.24 ml) was identified in the external validation set with a training sample size of 35. Compared to the volumetric overlap, the spatial overlap was poor with an average Dice similarity index of 0.14 (SD 0.16) in the external cohort, driven by subjects with very low lesion volumes.Discussion: We found that the performance of BIANCA, particularly the robustness of predictions, could be optimized for use in populations with a low WMH load by enlargement of the training sample size. Further work is needed to evaluate and potentially improve the prediction accuracy for low lesion volumes. These findings are important for current and future population-based studies with the majority of participants being normal aging people.

Validating the usefulness of sectorwise regression of visual field in the central 10°

2021 ◽  
pp. bjophthalmol-2020-317391
Author(s):  
Takashi Omoto ◽  
Hiroshi Murata ◽  
Yuri Fujino ◽  
Masato Matsuura ◽  
Takehiro Yamashita ◽  
...  
Keyword(s):  
Visual Field ◽  
Mean Absolute Error ◽  
Open Angle Glaucoma ◽  
Absolute Error ◽  
Open Angle ◽  
Clustering Method ◽  
Significant Difference ◽  
The Mean ◽  
Test Points

AimTo evaluate the usefulness of the application of the clustering method to the trend analysis (sectorwise regression) in comparison with the pointwise linear regression (PLR).MethodsThis study included 153 eyes of 101 patients with open-angle glaucoma. With PLR, the total deviation (TD) values of the 10th visual field (VF) were predicted using the shorter VF sequences (from first 3 to 9) by extrapolating TD values against time in a pointwise manner. Then, 68 test points were stratified into 29 sectors. In each sector, the mean of TD values was calculated and allocated to all test points belonging to the sector. Subsequently, the TD values of the 10th VF were predicted by extrapolating the allocated TD value against time in a pointwise manner. Similar analyses were conducted to predict the 11th–16th VFs using the first 10 VFs.ResultsWhen predicting the 10th VF using the shorter sequences, the mean absolute error (MAE) values were significantly smaller in the sectorwise regression than in PLR. When predicting from the 11th and 16th VFs using the first 10 VFs, the MAE values were significantly larger in the sectorwise regression than in PLR when predicting the 11th VF; however, no significant difference was observed with other VF predictions.ConclusionAccurate prediction was achieved using the sectorwise regression, in particular when a small number of VFs were used in the prediction. The accuracy of the sectorwise regression was not hampered in longer follow-up compared with PLR.

scholarly journals COMPARISON OF DIFFERENT CRITERIA IN THE PREVALENCE OF METABOLIC SYNDROME IN STUDENTS FROM PARANAVAÍ, PARANÁ

2019 ◽  
Vol 37 (3) ◽  
pp. 332-337 ◽  
Author(s):  
Flávio Ricardo Guilherme ◽  
Matheus Amarante do Nascimento ◽  
Carlos Alexandre Molena-Fernandes ◽  
Vânia Renata Guilherme ◽  
Stevan Ricardo dos Santos ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Confidence Interval ◽  
Children And Adolescents ◽  
Diagnostic Criteria ◽  
Public And Private ◽  
Significant Difference ◽  
Low Hdl ◽  
The Difference

ABSTRACT Objective: To investigate the difference in the proportion of students with metabolic syndrome, diagnosed according to different criteria. Methods: The sample consisted of 241 students (136 boys and 105 girls) aged 10 to 14 years, from public and private schools in Paranavaí, Paraná. We used three distinct diagnostic criteria for metabolic syndrome, considering the presence of at least three of the following risk factors: increased waist circumference, hypertension, fasting hyperglycemia, low HDL-C, and elevated triglycerides. Results: The prevalence of metabolic syndrome found was 1.7% (confidence interval of 95% - 95%CI 0-3.3) for the IDF criterion; 3.3% (95%CI 1.0-5.6) for Cook; and 17.4% (95%CI 12.6-22.3) for Ferranti. Analyzing the criteria in pairs, the agreement between IDF and Cook was 97.5% (k=0.95); between IDF and Ferranti, 83.4% (k=0.67); and between Cook and Ferranti, 85.9% (k=0.72). Onlyone student (0.4%) was diagnosed with metabolic syndrome solely by the IDF criterion, while 34 (14.1%) were diagnosed exclusively by Ferranti. The comparison of the three criteria showed that Ferranti presented the highest proportion of metabolic syndrome (p<0.001), and Cook had a greater proportion than IDF (p<0.001). Conclusions: We found a significant difference in the proportion of metabolic syndrome in the three criteria. The choice of which criterion to use can compromise not only the percentage of metabolic syndrome prevalence but also interfere in strategies of intervention and prevention in children and adolescents with and without metabolic syndrome, respectively.

Impact of Reducing Water Fluoride on Dental Caries and Fluorosis

2020 ◽  
pp. 002203452097877
Author(s):  
P. James ◽  
M. Harding ◽  
T. Beecher ◽  
D. Browne ◽  
M. Cronin ◽  
...  
Keyword(s):  
Primary Teeth ◽  
Fluoride Concentration ◽  
Permanent Teeth ◽  
Caries Experience ◽  
Caries Prevalence ◽  
Fluoride Toothpaste ◽  
Significant Difference ◽  
Policy Measures ◽  
The Difference ◽  
Water Fluoride

Guidance intended to reduce fluoride toothpaste ingestion in early childhood was introduced in Ireland in 2002. In 2007, water fluoride concentration was adjusted from 0.8–1.0 to 0.6–0.8 ppm. The objective of this study was to determine the difference in caries and fluorosis levels following introduction of these 2 policy measures. A before-and-after study compared caries and fluorosis in random samples of 8-y-olds in Dublin ( n = 707) and Cork-Kerry ( n = 1148) in 2017 with 8-y-olds in Dublin ( n = 679) and Cork-Kerry ( n = 565) in 2002. Dentinal caries experience (primary teeth, d3vcmft(cde)) and fluorosis (permanent teeth, Dean’s index of very mild or higher) were clinically measured. Lifetime exposure to community water fluoridation (CWF) was classified as “full CWF”/“no CWF.” Effect of examination year on caries prevalence and severity and fluorosis prevalence was assessed using multivariate regression adjusting for other explanatory variables. There was little change in commencement of fluoride toothpaste use at ≤24 mo following introduction of toothbrushing guidance. Among children with full CWF, there was no statistically significant difference in caries prevalence or severity between 2017 and 2002. In 2017, caries prevalence was 55% in Dublin (full CWF) and 56% in Cork-Kerry (full CWF), and mean d3vcmft(cde) among children with caries was 3.4 and 3.7, respectively. Caries severity was less in 2017 (mean 4.2) than 2002 (mean 4.9) among children with no CWF ( P = 0.039). The difference in caries severity between children with full CWF and no CWF was less in 2017 than in 2002 (interaction P = 0.013), suggesting a reduced benefit for CWF in 2017. In 2017, fluorosis prevalence was 18% in Dublin (full CWF) and 12% in Cork-Kerry (full CWF). Fluorosis was predominantly “very mild” with no statistically significant difference between 2017 and 2002. CWF at 0.6 to 0.8 ppm is an effective caries-preventive measure. Results suggested low uptake of toothbrushing guidance, a reduced caries-preventive effect for CWF in primary teeth, and no reduction in fluorosis following introduction of the policy measures.

scholarly journals A Comparison of Later Stage Dental Maturation in a Small Group of Children from Chernobyl and British Children

2018 ◽  
Vol 15 (1) ◽  
pp. 1-6
Author(s):  
H. M. Liversidge ◽  
C. E. A. Rogers
Keyword(s):  
Small Group ◽  
Third Molar ◽  
Permanent Teeth ◽  
Dental Age ◽  
Cross Sectional ◽  
Dental Maturation ◽  
Nuclear Disaster ◽  
Caucasian Origin ◽  
The Difference ◽  
British Children

The aim of this study was to investigate the dental radiographic development of a small group of children born in Chernobyl, Ukraine, around the time of the nuclear disaster with an age matched group of British children. The design was a cross sectional non random retrospective study consisting of five boys and five girls from Chernobyl (age range 10.03 to 12.37) and 20 age and sex matched British children of white Caucasian origin. Developing permanent mandibular teeth were assessed from rotational tomograms using criteria described by Demirjian, Goldstein and Tanner (1973). Third molar formation was also assessed. Dental age was calculated and compared to real age using a t-test. The difference in dental age (DA) and real age (RA) was not significant when the two groups were compared. Dental age in both groups of children was advanced compared to the standards. These results suggest that the Chernobyl disaster has not affected root formation of late forming permanent teeth of these children.

scholarly journals Comparison of tendency and accuracy in predicted post-operative refraction and recommended IOL power between IOL Master and VERION before and after optimizing IOL-constant in the VERION

2020 ◽  
Author(s):  
Takeshi Teshigawara ◽  
Akira Meguro ◽  
Nobuhisa Mizuki
Keyword(s):  
Mean Absolute Error ◽  
Anterior Chamber Depth ◽  
Absolute Error ◽  
Rank Test ◽  
K Value ◽  
Signed Rank ◽  
Before And After ◽  
Signed Rank Test ◽  
Iol Power ◽  
The Difference

Abstract Background: We assessed the accuracy and tendency of the VERION image-guided system (Alcon) and the intra-ocular lens (IOL) Master 700 (Zeiss), by comparing mean refractive shift (MRS) of predicted post-operative refraction (PPR), mean absolute error (MAE) of PPR, recommended IOL power (RIP) and K-value before and after optimizing the IOL-constant in VERION, to show the importance of optimization.Methods: This retrospective study involved 72 eyes. K-value was measured with both biometers. Axial length (AL) and anterior chamber depth (ACD) measured by the IOL Master were applied to the VERION because it cannot measure these variables. The User group for Laser Interference Biometry (ULIB) IOL-constant for the IOL Master was applied to the VERION before optimizing the IOL constant, since no such official measure was established for it. MRS of PPR, MAE of PPR, RIP and K-value as measured by both biometers were compared before and after optimizing the IOL-constant in the VERION. Finally, correlations between the MRS, MAE, RIP, and K-value were analyzed in the VERION. The Wilcoxon signed-rank test was used for analysis.Results: Compared to the IOL Master, K-value was significantly higher in the VERION. Prior to optimization, MRS of PPR showed a significant myopic shift in the VERION, and MAE of PPR was significantly higher. Additionally, RIP in the VERION was significantly lower. After optimization, there were no significant differences in the MRS of PPR and RIP between the VERION and IOL Master. MAE of PPR in the IOL Master was significantly higher than in the VERION. No significant correlations were found between MRS and MAE of PPR and RIP with K-value in the VERION. Conclusions: Before optimization, the VERION was less reliable in MRS, MAE and RIP than the IOL Master. However, after optimization, the difference in MRS and RIP between the two devices became insignificant. This study indicates that optimization of IOL-constant in the VERION is vital. After optimization, the VERION is more accurate in PPR than the IOL Master.

scholarly journals Detection of Enterococcus faecalis in Necrotic Teeth Root Canals by Culture and Polymerase Chain Reaction Methods

2007 ◽  
Vol 01 (04) ◽  
pp. 216-221 ◽  
Author(s):  
Dilsah COGULU ◽  
Atac UZEL ◽  
Ozant ONCAG ◽  
Semiha d AKSOY ◽  
Cemal ERONAT
Keyword(s):  
Polymerase Chain Reaction ◽  
Enterococcus Faecalis ◽  
Permanent Teeth ◽  
Deciduous Teeth ◽  
Chain Reaction ◽  
Test Species ◽  
Root Canals ◽  
Significant Difference ◽  
Polymerase Chain ◽  
The Difference

ABSTRACTObjectives: The aim of this study was to investigate the presence of Enterococcus faecalis in endodontic infections in both deciduous and permanent teeth by culture and polymerase chain reaction (PCR) methods.Methods: A total of 145 children aged 5-13 years old were involved in this study. The presence of E. faecalis in necrotic deciduous and permanent teeth root canals was studied using culture and polymerase chain reaction methods.Results: Among 145 molar teeth, 57% (n=83) presented necrotic asymptomatic pulp tissues and were included in this study. Culture and PCR methods detected the test species in 18 and 22 of 83 teeth involved, respectively. E. faecalis was cultured from 8 (18%) of 45 necrotic deciduous teeth and from 10 (26%) of 38 necrotic permanent teeth. PCR detection identified the target species in 10 (22%) and 12 (32%) of necrotic deciduous and permanent teeth respectively. Statistically significant difference in the presence of E. faecalis in deciduous and permanent teeth was found by culture and PCR methods (P=0.03 and 0.02, respectively). The difference in the presence of E. faecalis between two different methods was not statistically significant (P>.05).Conclusions: The results of the present study confirm that both culture and PCR methods are sensitive to detect E. faecalis in root canals. (Eur J Dent 2007;1:216-221)

scholarly journals Análise e Correlação da Distância Percorrida no Teste de Caminhada de Seis Minutos com a Distância Prevista por Meio de Três Equações de Referência

2017 ◽  
Vol 19 (1) ◽  
pp. 25
Author(s):  
Ivete Alonso Bredda Saad ◽  
Laís Bacchin de Oliveira ◽  
Eliana Pereira de Melo Costa ◽  
Mariana Borges de Oliveira ◽  
Bruna Scharlack Vian
Keyword(s):  
Mean Squared Error ◽  
Mean Absolute Error ◽  
Absolute Error ◽  
Work Capacity ◽  
Work Capacity Evaluation ◽  
Walk Distance ◽  
Squared Error ◽  
Significant Difference ◽  
Minute Walk Distance ◽  
Minute Walk

O teste de caminhada de seis minutos - TC6’- é amplamente utilizado para avaliação da capacidade física e do prognóstico de diversas doenças, em que a distância percorrida no TC6’ (DTC6’) é uma das principais variáveis para interpretá-lo. Vários estudos desenvolveram equações para obter a distância predita no TC6’ - DPTC6’, porém as equações de predição mais conhecidas na literatura foram desenvolvidas com indivíduos saudáveis. O objetivo deste estudo foi analisar e correlacionar a DTC6’com a DPTC6’ por meio das equações de Enright et al. e Iwama et al. em pacientes com doenças do aparelho respiratório e/ou cardiovascular e verificar o comportamento da variável idade entre as diferentes faixas etárias da população estudada. Foram analisados 350 testes realizados em indivíduos de 18 a 86 anos, separados em seis grupos por faixa etária. Calculou-se a correlação, o erro quadrático médio e erro absoluto médio para comparar DTC6’ com a DPTC6’ pelas equações. Observou-se correlação média positiva entre as DTC6’ e DPTC6’. Houve diferença estatisticamente significante (p<0.0001) entre as DTC6’ entre jovens e idosos. Os menores valores totais de erro quadrático médio e erro absoluto médio foram de Iwama et al. Concluiu-se que as três equações se correlacionam em intensidades parecidas com as distâncias percorridas. A variável idade interferiu nos resultados. A equação de Iwama et al. foi a que melhor previu a DTC6’ nos indivíduos em questão até os 50 anos de idade se assemelhando a equação de Enright e Sherrill nos grupos mais velhos. A equação de Troosters et al. superestimou a DTC6’ em todos os grupos etários.Palavras-chave: Doenças Respiratórias. Testes Respiratórios. Avaliação da Capacidade de Trabalho.AbstractThe six-minute walk test (6MWT) is widely used for evaluation of physical capacity and prognosis of various diseases and the six-minute walk distance (6MWD) is one of the main variable to interpret it. Several studies have developed equations to obtain the six-minute walk distance predicted values (6MWDP), however, the most known prediction equations in the literature were developed with healthy subjects. The aim of this study was to analyze and correlate the 6MWD to 6MWDP by three references equations for prediction, Enright et al. and Iwama et al. 350 tests performed were analyzed in patients aged18 to 86 years old, divided into six groups. Correlation, mean squared error and mean absolute error were calculated to compare the 6MWD to 6MWDP by the equations. There was a positive correlation between the average of 6MWD and 6MWDP. There was a significant difference (p <0.0001) in 6MWD between young and elderly people. The lowest total values of mean squared error and mean absolute error were from Iwama et al. It was concluded that the three predictive equations correlate in similar intensities with the distances walked. Iwamaet al.’s equation was the one that best predicts the 6MWD in groups with individuals up to 50 years old and was similar to Enright and Sherrill equation in older groups. Troosters et al. equation overestimated the 6MWD in all age groups.Keywords: Respiratory Tract Diseases. Breathing Tests. Work Capacity Evaluation.

scholarly journals Prakiraan Usia Gigi Menggunakan Standar Blenkin (Modifikasi Metode Demirjian) pada Anak-Anak Etnik Jawa di Kabupaten Jember

2020 ◽  
Vol 17 (2) ◽  
pp. 60
Author(s):  
Dwi Kartika Apriyono
Keyword(s):  
Age Estimation ◽  
Accurate Estimate ◽  
Permanent Teeth ◽  
Chronological Age ◽  
Age Difference ◽  
Dental Age ◽  
Dental Age Estimation ◽  
Panoramic Radiographs ◽  
Significant Difference ◽  
Age Range

Chronological and dental age are necessary aspects of dental age estimation. Both have a close relationship. Chronological age reflects the age of the tooth, and vice versa. Dental age estimation aims to provide the data in the field of dentistry with an accurate dental age range. In order to get the value of an accurate estimate of dental age, needed a method of estimation that has a standard deviation as low as possible and validated in a specific population groups of an individual. Demirjian method is a method frequently used in the dental age estimation. It uses the classification stages of the seven permanent teeth of mandibular left side using panoramic radiographs. Application of its method in some countries showed vary results so it needed adjustment. Blenkin standard is an adjustment of its method that changes the score of maturity stages 0-H to 1-8 and calculate the dental age by regression formula. The study aimed to assess the dental age estimation using Blenkin standard on children of Javanese ethnic in Jember region. This was an analytic descriptive study design. The samples were panoramic radiographs. The subjects were 70 samples consisting of 29 boys and 41 girls with an age range 6-12 years, and they were divided into 7 groups based on chronological age. Each tooth of the sample was calculated using Blenkin standard. The Blenkin standard showed non-significant difference with the age difference in the amount of approximately -0.22 years for boys and -0.03 years for girls (underestimation).

scholarly journals DETERMINATION OF DENTAL AGE OF 10-13 YEAR-OLD CHILDREN OF THE CARPATHIAN REGION OF UKRAINE BY THE CAMERIERE METHOD IN COMPARISON WITH THEIR CHRONOLOGICAL AGE

2019 ◽  
pp. 63-70
Author(s):  
V.F. Makieyev ◽  
O.O. Isakova
Keyword(s):  
Age Groups ◽  
High Accuracy ◽  
Permanent Teeth ◽  
Chronological Age ◽  
Age Group ◽  
Dental Age ◽  
Ray Method ◽  
Significant Difference ◽  
Age Range

Purpose:  to evaluate the chronological and dental age of children in Lviv and the Lviv region aged 10-13 years with the help of the modified formula Cameriere.  Methods. Оrthopantomograms  46 children (26 boys and 20 girls) aged 10-13 years from Lviv and Lviv region have been used for this study. A questionnaire was developed for the submission of individual patient data and a standardized format for making their indicators derived from orthopantomograms (OPG). The examination of the area of the lower seven teeth on the left was done using the Cameriere method and the age of the child was evaluated, which was further compared with the chronological age.  Results.The obtained results of the study showed a high accuracy and reliability of the estimation of dental age in children up to 10-13 years with the help of the Cameriere formula modified by us. The research is based on the detection of physiological changes (the rate of formation of the roots) in the permanent teeth of children using the X-ray method.  Evaluating the results obtained by two methods, among girls and boys of the selected age group, a statistically significant strong correlation between the chronological age and the age calculated by the Cameriere method was revealed. Cameriere research has been carried out in many countries around the world and, in particular, in European countries, by implementing the general formula. Children in the period of occlusive bite remain the most critical in terms of age and, therefore, the determination of the correct time for dental interventions. In this age group, the development of permanent teeth passes through different stages and depends on many factors of the environment, genetic, geographical and food factors. The process of teething also affects many local factors, such as space and space for a permanent tooth in the dental artery and the loss of temporary precursors. Even with a large number of factors affecting the eruption and formation of permanent teeth in children, this method showed high accuracy and independence. In order to assess the Cameriere method among the children under study and its further practical application, a comparison was made between the age obtained using this methodology and the chronological age of the children under study in different age groups, both among boys and girls. Analyzing the obtained data, it was found that the mean of chronological age among the studied boys aged 10-11 (n = 14) was 11.02 ± 0.59 years, and the Cameriere method was 10.63 ± 1.03 years.  Student's assessment did not reveal a significant difference between the data (p = 0.22) for the age group of 10-11 years.  Further analysis among the studied boys revealed that in the age group 12-13 years the average chronological age was 12.94 ± 0.49 years, and the age was determined by the Cameriere method 12.59 ± 0.63 years, and no significant difference was established between them  (p = 0.14). The results of the studies have shown the suitability of the Cameriere formula modified during the process, based on the assessment of open tops and the number of teeth with completed root formation as a marker for the physiological development of the child and one that can be used to determine the child's age.Since studies had a limited age range on a particular sample of dental patients, further studies should evaluate the utility of this method in a larger sample of children in the extended age range of the given region of Ukraine and, if possible, adjust the formula we modified for the stability of the averaged indicators in different samples by age and sex. 

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