Prevalence of Dal blood type and dog erythrocyte antigens (DEA) 1, 4, and 7 in canine blood donors in Italy and Spain

Data from potential feline blood donors presented at two university blood banks in Italy were recorded. Blood typing was performed using an immunochromatographic method. Over the three years of the study 357 cats representing 15 breeds, 45.3% female and 54.7% male, with a mean age of 3.8 years were evaluated. Of these 90.5% were blood type A, 5.6% type B, and 3.9% type AB. The majority of the cats (54.6%) were European DSH (92.3% were type A, 5.1% type B, and 2.6% type AB), and 21% were Maine Coon (MCO) cats (100% blood type A). The estimated frequencies of transfusion reactions following an unmatched transfusion between DSH (donors and recipients), MCO (donor and recipients), DSH donors and MCO recipients, and MCO donors and DSH recipients were 4.8%, 0%, 0%, and 5.1% for major reactions and 7.2%, 0%, 7.7%, and 0% for minor transfusions reactions, respectively. In a population of blood donors that includes DSH and MCO the risk of transfusion reaction is between 5% and 8% if typing is not performed on donor and recipient blood. Blood typing should therefore be performed before transfusion to remove the risk of transfusion reactions due to blood type incompatibilities.

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Classification of potential blood donors using machine learning algorithms approach

Jurnal Teknologi dan Sistem Komputer ◽

10.14710/jtsiskom.2020.13619 ◽

2020 ◽

Vol 8 (3) ◽

pp. 217-221

Author(s):

Merinda Lestandy ◽

Lailis Syafa'ah ◽

Amrul Faruq

Keyword(s):

Neural Network ◽

Machine Learning ◽

Blood Donor ◽

Blood Donors ◽

Naive Bayes ◽

Learning Algorithms ◽

Naïve Bayes ◽

Machine Learning Algorithms ◽

Blood Type ◽

The Neural Network

Blood donation is the process of taking blood from someone used for blood transfusions. Blood type, sex, age, blood pressure, and hemoglobin are blood donor criteria that must be met and processed manually to classify blood donor eligibility. The manual process resulted in an irregular blood supply because blood donor candidates did not meet the criteria. This study implements machine learning algorithms includes kNN, naïve Bayes, and neural network methods to determine the eligibility of blood donors. This study used 600 training data divided into two classes, namely potential and non-potential donors. The test results show that the accuracy of the neural network is 84.3 %, higher than kNN and naïve Bayes, respectively of 75 % and 84.17 %. It indicates that the neural network method outperforms comparing with kNN and naïve Bayes.

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Frequency of Minor Blood Group Antigens Among Hispanic-American Blood Donors in Southwest Texas.

Blood ◽

10.1182/blood.v114.22.4188.4188 ◽

2009 ◽

Vol 114 (22) ◽

pp. 4188-4188

Author(s):

Michael Silvey ◽

Rachel Beddard ◽

Yidong Chen ◽

Melissa Frei-Jones

Keyword(s):

Blood Group ◽

Race And Ethnicity ◽

Retrospective Cohort ◽

Blood Donors ◽

Conflicts Of Interest ◽

South Texas ◽

Blood Type ◽

Blood Group Antigens ◽

Hispanic American ◽

Antigen Testing

Abstract Abstract 4188 The frequency of minor blood group antigens has not been described among Hispanic blood donors. A retrospective cohort study was performed using the South Texas Blood and Tissue Center (STBTC) donor database, LifeTrak. Blood donors self-identified race and ethnicity. Caucasian and Hispanic donors were eligible. Donors who did not have minor antigen testing performed were not included. The STBTC has a high proportion of Hispanic blood donors (299047/779409, 38%), who are primarily of Mexican ancestry. Minor antigen testing was performed in 10% (74140/779409) of all donors; 8% (25394/299407) of Hispanic donors and 11% (42891/392074) of Caucasian donors. Hispanic donors were significantly more like to express blood type O Rh+ than Caucasian donors (13920/25394, 55% v 14947/74140, 35%; p<0.001). The frequency of ABO and RhD blood groups were similar to those reported previously in Caucasian and Hispanic donors (Garraty, et al. Transfusion, 2004). Of the minor antigens, expression of Rh E also differed significantly between Hispanic and Caucasian donors (4706/11744, 40% v 5416/19497, 28%; p<0.001). The prevalence of the other minor antigens were more similar and are reported in Figure 1. Complete Rh haplotypes were available in 8296 Caucasian donors and 7176 Hispanic donors. The haplotype RhDce differed significantly in 36% of Caucasians and 50% of Hispanics (3022/8296 v 3589/7176). The haplotype RhDce was previously reported as most common in African-Americans at 44% (Avent, et al. Blood, 2000). Haplotype RhDCE was found in 8% of Caucasians and 10% of Hispanics (660/8296 v 643/7176); haplotype RhDcE in 16% of Caucasians and 15% of Hispanics (1354/8296 v 1041/7176); and haplotype RhDCe was found in 39% of Caucasians and 27% of Hispanics (3260/8296 v 1903/7176). Differences exist in the frequency of minor blood group antigens among Caucasian and Hispanic blood donors in Southwest Texas. Disclosures: No relevant conflicts of interest to declare.

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Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis

Parasite ◽

10.1051/parasite/2018037 ◽

2018 ◽

Vol 25 ◽

pp. 36 ◽

Cited By ~ 5

Author(s):

Taiwu Wang ◽

Yifang Han ◽

Zuanqin Pan ◽

Hengzhong Wang ◽

Meng Yuan ◽

...

Keyword(s):

Toxoplasma Gondii ◽

Educational Level ◽

Blood Donors ◽

Detection Method ◽

Meta Analysis ◽

Mainland China ◽

Blood Type ◽

Central China ◽

Toxoplasma Gondii Infection ◽

Northeast Of China

Toxoplasma gondii transmitted from blood donors to receiving patients has become a concern as numerous articles about the epidemiology of T. gondii infection in blood donors from different provinces have been published in China. This study aimed to evaluate the seroprevalence of T. gondii infection in Chinese blood donors using a meta-analysis. A total of 40 eligible studies, published from 1986 to 2017 and covering 18 provinces and municipalities were included. Among a total of 49,784 Chinese blood donors, the overall IgG seroprevalence of T. gondii infection was 6.26% (95% CI: 4.62%–8.13%). The highest prevalence was in the Northeast of China and the lowest in Central China. The infection rate increased slowly over the years, but not significantly. A statistically significant correlation was found between the seroprevalence of T. gondii infection and the detection method and educational level (p < 0.01). There was no relationship between age, gender, occupation and blood type and seroprevalence of T. gondii (p > 0.05). The prevalence of antibodies to T. gondii in Chinese blood donors was lower than in other countries, but the risk of transfusion-transmitted toxoplasmosis still exits. More concise methods are still needed to evaluate the possibility of transfusion-transmitted toxoplasmosis from blood donors.

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The breed prevalence of Dog Erythrocyte Antigen 1.1 in the Onderstepoort area of South Africa and its significance in selection of canine blood donors

Journal of the South African Veterinary Association ◽

10.4102/jsava.v73i2.555 ◽

2002 ◽

Vol 73 (2) ◽

Cited By ~ 6

Author(s):

L.L. Van der Merwe ◽

L.S. Jacobson ◽

J.G. Pretorius

Keyword(s):

South Africa ◽

Blood Group ◽

Blood Donors ◽

German Shepherd ◽

Animal Blood ◽

Breed Differences ◽

Life Threatening ◽

Erythrocyte Antigen ◽

N 93 ◽

Dog Erythrocyte

The blood group antigen Dog Erythrocyte Antigen (DEA) 1.1 is clinically the most important canine blood group as DEA 1.1 antibodies are capable of causing acute haemolytic, potentially life-threatening transfusion reactions. Dogs do not have naturally occurring antibodies to DEA 1.1 but are rapidly sensitised by the first incompatible transfusion. The prevalence of DEA 1.1 in the general dog population is estimated at 42-46 %. Canine blood donors registered with the Onderstepoort Animal Blood Bank (n = 93) as well as potential donors (n = 140) were typed for DEA 1.1 using a monoclonal antibody card kit. All dogs came from the Onderstepoort area, near Pretoria, Gauteng province, South Africa. Overall prevalence of DEA 1.1 was 47 %. Prevalence was 47 % in purebred dogs and 48 % in mongrels. Distinct breed differences were noted with less than 20 % of German shepherd dogs and Boxers and greater than 75 % of Rottweilers, Great Danes, St Bernards and Dalmations testing DEA 1.1 positive. Knowledge of local breed differences will increase effectiveness of blood donor recruitment.

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Prevalence of dog erythrocyte antigens 1, 4, and 7 in galgos (Spanish Greyhounds)

Journal of Veterinary Diagnostic Investigation ◽

10.1177/1040638715592025 ◽

2015 ◽

Vol 27 (4) ◽

pp. 558-561 ◽

Cited By ~ 7

Author(s):

Eva Spada ◽

Daniela Proverbio ◽

Luis Miguel Viñals Flórez ◽

Maria del Rosario Perlado Chamizo ◽

Roberta Perego ◽

...

Keyword(s):

Blood Donors ◽

Blood Donation ◽

Jugular Vein ◽

Physical Characteristics ◽

Blood Samples ◽

Blood Types ◽

Cell Counts ◽

Erythrocyte Antigen ◽

Relative Prevalence ◽

Dog Erythrocyte

Galgos (Spanish Greyhounds), in common with other sighthounds, have higher hematocrits, hemoglobin concentrations, and red blood cell counts than other breeds. In addition to these hematological characteristics, the physical characteristics of these dogs (medium to large dogs with an easily accessible jugular vein and a good temperament) make galgos ideal blood donors. However, to date, there are only published reports concerning dog erythrocyte antigen (DEA) 1 in this breed. Information on DEAs 4 and 7 would be useful when recruiting blood donors to donation programs, as DEA 1 and 7–negative and DEA 4–positive dogs can be considered universal donors. Ethylenediamine tetra-acetic acid–anticoagulated jugular blood samples were collected from 205 galgos. Dogs were aged between 1 and 10 years, 102 were female (49.8%) and 103 male (50.2%), and all were living in South Madrid, Spain. All 205 blood samples were tested for DEA 1 by card agglutination, and 150 of these samples were tested for DEA 4 and DEA 7 by gel column agglutination using polyclonal anti-DEA antibodies. Of the 205 galgos blood samples typed, 112 out of 205 (54.6%) were positive for DEA 1. Of the 150 blood samples tested, all (150/150, 100%) were positive for DEA 4, and 12 out of 150 (8%) samples tested positive for DEA 7. Of these samples, 70 out of 150 (46.7%) were positive only for DEA 4. There was no relationship between blood types and sex. In addition to the hematological characteristics previously reported and the physical characteristics of these dogs, the relative prevalence of blood types DEA 1, 4, and 7 make galgos good candidates for blood donation in blood donor programs.

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Frequency of dog erythrocyte antigen 1 blood group and risk of incompatible transfusion in dogs of different breeds and mongrels from the city of Salvador - BA, Brazil

Brazilian Journal of Veterinary Research and Animal Science ◽

10.11606/issn.1678-4456.bjvras.2019.154865 ◽

2019 ◽

Vol 56 (3) ◽

pp. e154865

Author(s):

Suzana Cláudia Spínola dos Santos ◽

Mariane Melo dos Santos ◽

Wellington Francisco Rodrigues ◽

Roberto Meyer ◽

Maria de Fátima Dias Costa

Keyword(s):

Flow Cytometry ◽

Blood Group ◽

Blood Type ◽

Blood Transfusions ◽

Blood Typing ◽

Reaction Test ◽

Erythrocyte Antigen ◽

The City ◽

Dog Erythrocyte ◽

Group 1

The dog erythrocyte antigen 1 (DEA 1) is the most immunogenic blood group in dogs, and blood transfusions may trigger some undesirable effects in veterinary patients, which are directly associated with incompatible transfusions. The present study aimed to investigate the frequency of positive DEA 1 blood group in blood donor dogs from a blood bank in Salvador, Bahia, Brazil, and also to calculate the risk of managing incompatible blood in both first and second transfusion. A number of 203 dogs of different breeds, aged between 1 and 8 years, weighing 28 kg, with no degree of kinship and of both sexes in Salvador - BA, Brazil were evaluated to investigate the blood type DEA 1 frequency, by means of chromatography and flow cytometry tests for blood typing. The risk of incompatible blood transfusion in either a first or a second transfusion was also calculated. The frequency of the DEA 1 group ranged from 0% to 100% in various breeds, but with a mean positivity of 62.07% (126/203). And the lowest risk of an DEA 1 negative animal receiving DEA 1 positive blood within the group of animals evaluated was 0.92% at a first transfusion; and the risk of the same animal receiving incompatible blood for the DEA group 1 in the second transfusion was 0.008%. The highest risk of an DEA 1 negative animal receiving DEA 1 positive blood from these animals was 69.12%; and the risk of receiving incompatible blood for DEA 1 was 47.77%. In conclusion, the frequency of the DEA 1 group varied between the studied breeds and the risk of incompatible blood transfusions varies according to donor and recipiente breeds, but this can be overridden if blood typing tests are performed along with the cross-reaction test for compatibility.

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PROPORTION OF RHESUS BLOOD TYPE PHENOTYPES OF ROUTINE BLOOD DONORS AT BLOOD DONOR UNIT INDONESIAN RED CROSS IN BANDUNG CITY

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY ◽

10.24293/ijcpml.v25i2.807 ◽

2019 ◽

Vol 25 (2) ◽

pp. 155

Author(s):

Ivana Dewi ◽

Nadjwa Zamalek Dalimoenthe ◽

Anna Tjandrawati ◽

Nida Suraya

Keyword(s):

Blood Donor ◽

Blood Donors ◽

Blood Donation ◽

Ethylenediaminetetraacetic Acid ◽

Blood Type ◽

Red Cross ◽

Cross Sectional ◽

Matching Problems ◽

Routine Blood ◽

Hemolytic Transfusion Reaction

Blood type phenotype incompatibility including Rhesus between donors and patients may result in cross-matching problems, triggering alloimmunization, and caused Hemolytic Transfusion Reaction (HTR). Rhesus blood type incompatibility between mother and fetus may cause Hemolytic Disease of Fetus and Newborn (HDFN). Pretransfusion phenotypic blood groups matching also reduce cost efficiently which means antibody screening is no longer needed. The purpose of the study is to find the proportion Rhesus blood type phenotypes in routine blood donors at Blood Donor Unit, Indonesian Red Cross in Bandung city, Indonesia.The study is a descriptive and observational with cross sectional design. The study was done at Blood Donor Unit, Indonesian Red Cross in Bandung city from April 2016 to September 2017. The subjects were 142 routine blood donors, blood sampling was done simultaneously with blood donation. Rhesus antigen examination of ethylenediaminetetraacetic acid (EDTA) blood was done by gel method. Subjects characteristics were male (68%) and female (32%), with the mean age was 39 years. Examination of Rhesus antigen were found antigen D(100%), antigen e(98,6%), antigen C(97,9%), antigen c(38,7%) and antigen E(31,7%). Results of Rhesus phenotypes were DCe/DCe(61,3%), DCe/DcE(29,6%), DCe/dce(7%), DcE/DcE(1,4%) and DcE/dce(0.7%). The distribution of Rhesus blood type were affected by factors such as genetics, race, ethnicity, marriage, demography, and migration. Rhesus blood phenotypes proportion in routine blood donors at Blood Donor Unit, Indonesian Red Cross in Bandung city sorted from the most are DCe/DCe, DCe/DcE, DCe/dce, DcE/DcE and DcE/dce.Keywords: blood donor, phenotype, Rhesus

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Associations between seroprevalence of Helicobacter pylori and ABO/rhesus blood group antigens in healthy blood donors in southwest Iran

Journal of International Medical Research ◽

10.1177/03000605211058870 ◽

2021 ◽

Vol 49 (12) ◽

pp. 030006052110588

Author(s):

Azar Dokht Khosravi ◽

Mehrandokht Sirous ◽

Morteza Saki ◽

Sakineh Seyed-Mohammadi ◽

Seyed Reza Modares Mousavi ◽

...

Keyword(s):

Helicobacter Pylori ◽

Blood Group ◽

Blood Donors ◽

Blood Groups ◽

Blood Type ◽

Enzyme Linked Immunosorbent Assay ◽

Blood Group Antigens ◽

Chi Square ◽

Cytotoxin Associated Gene A ◽

H Pylori

Objective To investigate correlations between ABO/rhesus (Rh) blood group antigens and anti- Helicobacter pylori and anti-cytotoxin-associated gene A (CagA) seropositivity in blood donors. Methods A total of 311 blood donors were enrolled. ABO and Rh blood groups were determined using hemagglutination tests. Specific anti- H. pylori IgG and anti-CagA IgG antibodies in sera were quantitated by enzyme-linked immunosorbent assay. Correlations between blood groups and anti- H. pylori and anti-CagA seropositivity were evaluated using the Chi-square test. Results O+ was the most frequent blood type (38%, n = 118). Anti- H. pylori IgG seropositivity was observed in 240 (77.2%) blood donors, while anti-CagA IgG seropositivity was observed in 132 (42.5%) blood donors. Although seropositivity rates for both anti- H. pylori and anti-CagA IgG were higher in individuals with blood type O, no statistically significant associations were observed between seropositivity and any ABO/Rh blood groups. Conclusion Individuals with blood type O may have higher rates of H. pylori seropositivity.

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The prevalence of antibodies to SARS-CoV-2 among blood donors in China

10.1101/2020.07.13.20153106 ◽

2020 ◽

Cited By ~ 3

Author(s):

Le Chang ◽

Wanghen Hou ◽

Lei Zhao ◽

Yali Zhang ◽

Yanbin Wang ◽

...

Keyword(s):

Blood Donors ◽

Blood Donation ◽

Cross Sectional Study ◽

Blood Type ◽

Igg Antibody ◽

Cross Sectional ◽

Viral Spread ◽

Independent Risk Factors ◽

Effective Public Health ◽

Central South

Objectives The prevalence of antibodies to SARS-CoV-2 among blood donors in China remains unknown. To reveal the missing information, we investigated the seroprevalence of SARS-CoV-2 antibodies among blood donors in the cities of Wuhan, Shenzhen, and Shijiazhuang of China. Design Cross-sectional study Setting Three blood centers, located in the central, south and north China, respectively, recruiting from January to April 2020. Participants 38,144 healthy blood donors donated in Wuhan, Shenzhen and Shijiazhuang were enrolled, who were all met the criteria for blood donation during the COVID-19 pandemic in China. Main outcome measures Specific antibodies against SARS-CoV-2 including total antibody (TAb), IgG antibody against receptor-binding domain of spike protein (IgG-RBD) and nucleoprotein (IgG-N), and IgM. Pseudotype lentivirus-based neutralization test was performed on all TAb-positive samples. In addition, anonymous personal demographic information, including gender, age, ethnicity, occupation and educational level, and blood type were collected. Results A total of 519 samples from 410 donors were confirmed by neutralization tests. The SARS-CoV-2 seroprevalence among blood donors was 2.29% (407/17,794, 95%CI: 2.08% to 2.52%) in Wuhan, 0.029% (2/6,810, 95%CI: 0.0081% to 0.11%) in Shenzhen, and 0.0074% (1/13,540, 95%CI: 0.0013% to 0.042%) in Shijiazhuang, respectively. The earliest emergence of SARS-CoV-2 seropositivity in blood donors was identified on January 20, 2020 in Wuhan. The weekly prevalence of SARS-CoV-2 antibodies in Wuhan's blood donors changed dynamically and were 0.08% (95%CI: 0.02% to 0.28%) during January 15 to 22 (before city lockdown), 3.08% (95%CI: 2.67% to 3.55%) during January 23 to April 7 (city quarantine period) and 2.33% (95%CI: 2.06% to 2.63%) during April 8 to 30 (after lockdown easing). Female and older-age were identified to be independent risk factors for SARS-CoV-2 seropositivity among donors in Wuhan. Conclusions The prevalence of antibodies to SARS-CoV-2 among blood donors in China was low, even in Wuhan city. According to our data, the earliest emergence of SARS-CoV-2 in Wuhan's donors should not earlier than January, 2020. As most of the population of China remained uninfected during the early wave of COVID-19 pandemic, effective public health measures are still certainly required to block viral spread before a vaccine is widely available.

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