scholarly journals Does clinical outcome of birch pollen immunotherapy relate to induction of blocking antibodies preventing IgE from allergen binding? A pilot study monitoring responses during first year of AIT

Author(s):  
Sara Huber ◽  
Roland Lang ◽  
Markus Steiner ◽  
Lorenz Aglas ◽  
Fatima Ferreira ◽  
...  
2005 ◽  
Vol 11 (1) ◽  
pp. 71-97 ◽  
Author(s):  
J. Paul Grayson

In order to test the general utility of models developed in the US for explaining university outcomes of Canadian and international students, a three year study is currently underway at four Canadian universities. As a first step in this research, a pilot study with two objectives was conducted at York University in Toronto. The first objective is to compare the experiences and outcomes of domestic and international students in their first year of study. The second objective is to test the applicability of a parsimonious general model of student outcomes derived from examinations of American students to Canadian and international students studying in Canada. The specific outcomes examined are academic achievement, credit completion, and program satisfaction in the first year of study.


Author(s):  
Bettina Nothegger ◽  
Norbert Reider ◽  
Claudia E. Covaciu ◽  
Valentina Cova ◽  
Linda Ahammer ◽  
...  
Keyword(s):  
Phase Ii ◽  

2021 ◽  
Vol 11 (6) ◽  
pp. 263
Author(s):  
Chris Campbell ◽  
Tran Le Nghi Tran

This paper reports on a pilot study that was conducted during a technical trial of a new ePortfolio system at a large Australian university. Students from a large (n = 325) first-year educational technology course were given the opportunity to use the new ePortfolio system weekly as part of their reflective practice at the end of the hands-on tutorial classes and also through a blogging assignment that required six posts throughout the semester. Although the students reflecting on their work and ePortfolios themselves are not new concepts, this paper reports how assessment practices can be improved using ePortfolios and how students can improve their reflective practice through simple and regular use throughout the 12-week semester that the study was conducted. From the class, 208 students responded to the survey with the results being positive. The students were able to use the system easily and did not report many problems with crashing or freezing. The lessons learnt form an important part of this study for future iterations with these reported in the paper.


2017 ◽  
Vol 117 (08) ◽  
pp. 1644-1650 ◽  
Author(s):  
Timo Bömicke ◽  
Christian Valina ◽  
Christian Stratz ◽  
Michael Amann ◽  
Franz-Josef Neumann ◽  
...  

SummaryIt is unknown whether the known association of high on-treatment platelet reactivity (HTPR) with worse clinical outcome in patients on clopidogrel following coronary stent implantation persists after planned discontinuation of clopidogrel. This study investigated the association of HTPR with major ischaemic events after planned discontinuation of clopidogrel. Consecutive patients undergoing elective coronary stent implantation after loading with clopidogrel 600 mg were followed for up to seven years (n=765). Platelet reactivity was tested on day 1 after coronary intervention. Clopidogrel was continued for six months after implantation of drug-eluting stents and for one month if only bare-metal stents were used. The combined primary endpoint was death of any cause or non-fatal myocardial infarction (MACE). HTPR was found in 217 of 765 patients (28%). During a median follow-up of 5.7 years, the primary endpoint occurred in 145 subjects after planned discontinuation of clopidogrel. Patients with HTPR showed a higher incidence of MACE after discontinuation of clopidogrel. There was a significant interaction of HTPR and time following discontinuation of clopidogrel beyond one year (p for interaction 0.08). Landmark analyses confirmed that the association of HTPR and MACE was only significant within the first year (HR: 2.93, 95%-CI 1.13–7.60, p=0.03), but not beyond the first year following discontinuation of clopidogrel (HR: 1.19, 95%-CI 0.82–1.72, p=0.37). In conclusion, patients with HTPR persist to be at high risk for death or myocardial infarction even following planned discontinuation of clopidogrel. However, this association was only significant for the first year following discontinuation of clopidogrel.


Author(s):  
Veena Thamban ◽  
Kavana G. Venkatappa ◽  
Swarnalatha P. K. ◽  
Sparshadeep E. M.

Background: Anemia among women causes many serious health problems and is pervasive in developing country. Many research studies have documented that malnutrition affects body growth and development, especially during the crucial period of adolescence. The association between anemia and body mass index (BMI) is a measure of nutrition and health status of adults. Aim was to study the association between anemia and BMI among female students.Methods: An observational study was conducted among first year medical and dental female students (n=109) aged 18-20years. Hemoglobin (Hb) levels (g/dL) by Sahli’s hemoglobinometer and BMI (kg/m2) were estimated. Anemia was defined as Hb content <12g/dL. Subjects were classified by BMI categories as underweight (BMI <18.5kg/m2), normal weight (BMI:18.5-24.99kg/m2), overweight (BMI ≥25kg/m2) and obesity (BMI ≥30kg/m2) according to WHO. Then the relation between anemia and BMI were statistically analyzed.Results: Overall, 48.62% female students were anemic. Of which 43.4% were underweight, 22.6% normal weight and 34.5% were above normal weight (over weight and obese). Mean value of hemoglobin was significantly decreased in underweight and overweight compared to normal weight (p<0.001). Anemia was significantly associated with BMI (χ2 =46.48, p=0.000).Conclusions: The study concludes the occurrence of anemia in both undernourished and over-nourished individuals which were significantly associated. Further studies are needed with larger sample size to document the factors that may be associated with anemia in females.


Author(s):  
Peter R. Johnston ◽  
Dianne J. Watters ◽  
Christopher L. Brown ◽  
Michael L. Williams ◽  
Wendy A. Loughlin

Author(s):  
Peter Watt ◽  
George Boak ◽  
Marija Krlic ◽  
Dawn Heather Wilkinson ◽  
Jeff Gold

This reflective case-history presents the findings of a 12-week pilot study of a collaborative organizational change project which oversaw the implementation of predictive policing technology (PPT) into a territorial police force in the North of England. Based on the first year of a two-year initiative, the reflections consider the impact on the future of the project and their potential future application and cultural embeddedness, beyond the organizational and time-bound specifics of this case.


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